公开(公告)号：US09504754B2

公开(公告)日：2016-11-29

申请号：US14213063

申请日：2014-03-14

Applicant: South Dakota Board of Regents

Inventor： Hemachand Tummala ,  Sunny Kumar

IPC: A61K47/48 ,  A61K31/12

CPC classification number: A61K47/48176 ,  A61K31/12 ,  A61K47/58

Abstract: Methods and materials relating to a medicament preparation comprising a curcuminoid component and a euradit component provided as a curcuminoid-eudragit complex, which enhance the bioavailability of the curcumin component and are useful for the treatment of various diseases including cancer, neurodegeneration, inflammation, and immunodeficiency. In some aspects, the curcuminoid component comprises curcumin to prepare a curcumin-eudragit complex and a medicament comprising curcumin-eudragit complexes.

Abstract translation: 涉及一种药物制剂的方法和材料，所述药物制剂包含姜黄素组分和作为姜黄素 - 黑曲霉复合物提供的euradit组分，其增强姜黄素组分的生物利用度，并且可用于治疗各种疾病，包括癌症，神经变性，炎症和免疫缺陷 。 在一些方面，姜黄素组分包含姜黄素以制备姜黄素 - udragit复合物和包含姜黄素 - udragit复合物的药物。

公开(公告)号：US20160263227A1

公开(公告)日：2016-09-15

申请号：US15065723

申请日：2016-03-09

Applicant: South Dakota Board of Regents

Inventor： Ying Deng ,  Bo Yang

IPC: A61K47/34 ,  A61K31/4745 ,  A61K31/155

CPC classification number: A61K31/4745 ,  A61K31/155

Abstract: A method of producing a drug-loaded Poly (Glycerol Sebacate) (PGS) comprising providing PGS; dissolving at least one drug in a solvent; incubating the PGS in the solvent; and evaporating the solvent.

Abstract translation: 包括提供PGS的药物负载聚（癸二酸甘油酯）（PGS）的制备方法; 将至少一种药物溶解在溶剂中; 在溶剂中培养PGS; 并蒸发溶剂。

公开(公告)号：US20150311504A1

公开(公告)日：2015-10-29

申请号：US14696435

申请日：2015-04-25

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： Haiping Hong ,  David R. Salem ,  Gregory Lee Christensen ,  Ruidong Yang

IPC: H01M4/36 ,  H01M4/525 ,  H01M4/505 ,  H01M4/04 ,  H01M4/583 ,  H01M4/38 ,  H01M4/62 ,  H01M10/052 ,  H01M4/52 ,  H01M4/485

CPC classification number: H01M4/133 ,  B82Y30/00 ,  H01M4/0404 ,  H01M4/0419 ,  H01M4/0471 ,  H01M4/131 ,  H01M4/134 ,  H01M4/1391 ,  H01M4/1393 ,  H01M4/362 ,  H01M4/364 ,  H01M4/38 ,  H01M4/386 ,  H01M4/387 ,  H01M4/485 ,  H01M4/505 ,  H01M4/52 ,  H01M4/523 ,  H01M4/525 ,  H01M4/583 ,  H01M4/587 ,  H01M4/62 ,  H01M4/622 ,  H01M4/623 ,  H01M4/661 ,  H01M4/70 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0585 ,  H01M2004/028

Abstract: An electrode comprises carbon nanoparticles and at least one of metal particles, metal oxide particles, metalloid particles and/or metalloid oxide particles. A surfactant attaches the carbon nanoparticles and the metal particles, metal oxide particles, metalloid particles and/or metalloid oxide particles to form an electrode composition. A binder binds the electrode composition such that it can be formed into a film or membrane. The electrode has a specific capacity of at least 450 mAh/g of active material when cycled at a charge/discharge rate of about 0.1C.

Abstract translation: 电极包括碳纳米颗粒和金属颗粒，金属氧化物颗粒，准金属颗粒和/或准金属氧化物颗粒中的至少一种。 表面活性剂将碳纳米颗粒和金属颗粒，金属氧化物颗粒，准金属颗粒和/或准金属氧化物颗粒附着以形成电极组合物。 粘合剂结合电极组合物，使得其可以形成膜或膜。 当以约0.1C的充电/放电速率循环时，电极具有至少450mAh / g的活性材料的比容量。

公开(公告)号：US20150302948A1

公开(公告)日：2015-10-22

申请号：US14577552

申请日：2014-12-19

Applicant: SOUTH DAKOTA BOARD OF REGENTS ,  GEORGIA TECH RESEARCH CORPORATION

Inventor： Haiping Hong ,  G.P. (Bud) Peterson ,  David R. Salem

IPC: H01B1/24 ,  H01F1/01

CPC classification number: H01B1/24 ,  C08K3/04 ,  C08K3/041 ,  C08K3/042 ,  C08K3/045 ,  C08K3/046 ,  C08K3/08 ,  C08K3/22 ,  C08K2003/2265 ,  C08K2003/2272 ,  C08K2003/2275 ,  C08K2003/2289 ,  C08K2003/2293 ,  C08K2201/011 ,  H01B1/04 ,  H01F1/01 ,  H01F1/447 ,  C08L63/00

Abstract: Magnetically aligned carbon nanoparticle composites have enhanced electrical properties. The composites comprise carbon nanoparticles, a host material, magnetically sensitive nanoparticles and a surfactant. In addition to enhanced electrical properties, the composites can have enhanced mechanical and thermal properties.

Abstract translation: 磁性排列的碳纳米颗粒复合材料具有增强的电性能。 复合材料包括碳纳米颗粒，主体材料，磁敏纳米颗粒和表面活性剂。 除了增强的电学性能，复合材料可以具有增强的机械和热性能。

公开(公告)号：US12280057B2

公开(公告)日：2025-04-22

申请号：US17447101

申请日：2021-09-08

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： Hunter Moyer ,  Daniel Heglund

IPC: A61K31/522 ,  A61K31/21 ,  A61K31/5415 ,  A61K31/655 ,  A61K33/06 ,  A61K47/44 ,  A61P7/08 ,  A61P9/08

Abstract: The present disclosure relates to compositions and systems for improving tissue perfusion such that blood flow is increased, improving tissue healing time and reducing or eliminating tissue necrosis. In a preferred embodiment, the compositions comprise a phosphodiesterase inhibitor, a calcium channel blocker, a nitric oxide producer, and an α-adrenergic antagonist. Methods of making the compositions and using the compositions are also disclosed.

公开(公告)号：US20250024774A1

公开(公告)日：2025-01-23

申请号：US18776858

申请日：2024-07-18

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： Ali Mirzakhani Nafchi

IPC: A01C21/00 ,  A01C7/06 ,  A01C7/08 ,  A01C7/10 ,  A01C19/02

Abstract: A precision planter having a frame configured to transport the precision planter through a crop area, at least one hopper coupled to the frame, and a seed dispersion system coupled to the frame. The seed dispersion system comprises a first seed meter, a funnel, and a seed dispersion tube, each configured to receive a first seed mix, which may include one or more types of seeds and/or fertilizer. The system also includes a fan, a seed dispersion tube, a seed dispersion head, and a plurality of seed hoses configured to deliver the first seed mix to the crop area. The seed dispersion system is configured to implement a prescription map of the crop area including at least two cover crop zones corresponding to seed mix(es) and or fertilizer prescriptions, which are determined based on location data. The seed dispersion system is configured to dispense the first seed mix at a first seed dispersion rate in the first cover crop zone.

公开(公告)号：US20240417296A1

公开(公告)日：2024-12-19

申请号：US18706315

申请日：2022-11-03

Applicant: South Dakota Board of Regents

Inventor： Maryam Amouamouha ,  Travis W. Walker

IPC: C02F3/00 ,  C02F1/44 ,  C02F1/461 ,  C02F1/66 ,  C02F3/28

Abstract: An anaerobic bioreactor with electrolytic regeneration system, method and apparatus for monitoring pH levels which is simultaneously efficient in both anaerobic digestion and optimized filtration process is disclosed. To maintain the pH stability of an anaerobic bioreactor, an electrolysis process is integrated with the bioreactor. The integration of an electrolysis process with the bioreactor sustains the pH in the optimized range for anaerobic process while enhancing the removal of contaminants in the bioreactor, augmenting biogas production, and mitigating fouling.

公开(公告)号：US20240316583A1

公开(公告)日：2024-09-26

申请号：US18733412

申请日：2024-06-04

Applicant: South Dakota Board of Regents

Inventor： Christian Widener ,  Victor Champagne ,  Matthew Trexler ,  Dennis Helfritch ,  Rob Hrabe

IPC: B05B7/16 ,  B05B7/14 ,  C23C24/04

CPC classification number: B05B7/1693 ,  B05B7/1486 ,  B05B7/1613 ,  C23C24/04

Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.

公开(公告)号：US12084193B2

公开(公告)日：2024-09-10

申请号：US17657534

申请日：2022-03-31

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： Haiping Hong ,  Christian Widener ,  Gregory Lee Christensen

IPC: B64D31/06 ,  B64D31/04 ,  B64D31/08 ,  B64D43/00 ,  C08K3/04 ,  C08K3/38 ,  C09D5/24 ,  C09D7/61 ,  C09D133/02 ,  C09D163/00 ,  C09D175/04 ,  G05D1/00

CPC classification number: B64D31/06 ,  B64D31/04 ,  B64D31/08 ,  B64D43/00 ,  C08K3/04 ,  C08K3/38 ,  C08K2201/001 ,  C09D5/24 ,  C09D7/61 ,  C09D133/02 ,  C09D163/00 ,  C09D175/04 ,  G05D1/0661

Abstract: Disclosed herein is a conductive coating composition that includes a functionalized carbon nanomaterial and/or boron nanomaterial and a fluid component. The nanomaterial and fluid component forms hydrogen bond network in the disclosed composition. Because of the formed hydrogen bonds, the disclosed coating exhibits enhanced thermal or electrical conductivity. Also disclosed is a method to improve thermal or electrical conductivity of an existing coating composition.

公开(公告)号：US11998942B2

公开(公告)日：2024-06-04

申请号：US17684921

申请日：2022-03-02

Applicant: South Dakota Board of Regents

Inventor： Christian Widener ,  Victor Champagne ,  Matthew Trexler ,  Dennis Helfritch ,  Rob Hrabe

IPC: B05B7/16 ,  B05B7/14 ,  C23C24/04

CPC classification number: B05B7/1693 ,  B05B7/1486 ,  B05B7/1613 ,  C23C24/04

Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.