公开(公告)号：US20140074059A1

公开(公告)日：2014-03-13

申请号：US13612506

申请日：2012-09-12

申请人： Frances Wilson HOWELL ,  Janice MACLEOD ,  David RODBARD

发明人： Frances Wilson HOWELL ,  Janice MACLEOD ,  David RODBARD

IPC分类号： A61M5/168

CPC分类号： A61M5/14244 ,  A61M5/1723 ,  A61M2005/14208 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3592 ,  G06F19/3468

摘要： Various methods and system to provide insight into how certain commands to a patient's infusion pump impact glycemic control of the subject. These patterns help to identify very specific areas of glycemic excursions, enable patients and HCPs to more easily identify patterns of hypoglycemia and hyperglycemia in order to take steps to improve glycemic control of the person with diabetes.

摘要翻译： 各种方法和系统提供洞察患者输液泵的某些命令如何影响受试者的血糖控制。 这些模式有助于识别非常具体的血糖偏移范围，使患者和HCPs能够更容易地识别低血糖和高血糖模式，以采取措施来改善糖尿病患者的血糖控制。

公开(公告)号：US08556867B2

公开(公告)日：2013-10-15

申请号：US13203697

申请日：2010-01-27

申请人： Peter Krulevitch ,  Robert Wilk ,  Ulrich Kraft ,  Donna Savage ,  Nick Foley ,  James Glencross ,  David Shepherd ,  Zara Sieh ,  David Price

发明人： Peter Krulevitch ,  Robert Wilk ,  Ulrich Kraft ,  Donna Savage ,  Nick Foley ,  James Glencross ,  David Shepherd ,  Zara Sieh ,  David Price

IPC分类号： A61M5/315 ,  A61M5/178 ,  A61M5/00

CPC分类号： A61M5/315 ,  A61B5/002 ,  A61B5/14532 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/3146 ,  A61M5/31525 ,  A61M5/31551 ,  A61M2005/3126 ,  A61M2005/3142 ,  A61M2205/14 ,  A61M2205/18 ,  A61M2205/215 ,  A61M2205/3317 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3569 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/584 ,  A61M2205/6054 ,  A61M2205/6081 ,  A61M2205/8212 ,  A61M2209/04 ,  G01D5/1655 ,  G06F19/00 ,  G06F19/3468

摘要： Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reuse of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.

摘要翻译： 提供了“智能”药物递送系统的各种实施例，其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。 附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传送与胰岛素相关的信息 剂量和注射到数据管理单元，提供提醒，错误警告或关于针的不正确使用或重复使用的信息，笔上留下的药物的轨迹量或笔的使用持续时间，关于药物到期的时间，或 提供用于定位放错的笔和模块的声音报警器。 还描述了使用药物递送系统的方法。

公开(公告)号：US08551320B2

公开(公告)日：2013-10-08

申请号：US12464935

申请日：2009-05-13

申请人： Alastair M. Hodges ,  Ronald C. Chatelier

发明人： Alastair M. Hodges ,  Ronald C. Chatelier

IPC分类号： G01F1/64 ,  G01N17/00 ,  G01N27/26

CPC分类号： G01N27/3274

摘要： Methods for calculating an analyte concentration of a sample are provided. In one exemplary embodiment the method includes steps that are directed toward accounting for inaccuracies that occur as a result of temperature variations in a sample, a meter, or the surrounding environment. In another exemplary embodiment the method includes steps that are directed toward determining whether an adequate sample is provided in a meter because insufficient samples can result in inaccuracies. The methods that are provided can be incorporated into a variety of mechanisms, but they are primarily directed toward glucose meters for blood samples and toward meters for controls solutions.

摘要翻译： 提供了用于计算样品的分析物浓度的方法。 在一个示例性实施例中，该方法包括针对由于样品，仪表或周围环境中的温度变化而发生的不准确性的步骤。 在另一示例性实施例中，该方法包括以下步骤：针对确定在仪表中是否提供了足够的样品，因为不足的样品可导致不准确。 所提供的方法可以并入多种机制中，但是它们主要针对血液样品的血糖仪和用于对照溶液的米。

公开(公告)号：US08486245B2

公开(公告)日：2013-07-16

申请号：US13076413

申请日：2011-03-30

申请人： Neil Roberts ,  Gary Smeaton

发明人： Neil Roberts ,  Gary Smeaton

IPC分类号： G01N27/327

CPC分类号： G01N27/3274

摘要： Electrochemical measurement techniques for measuring the concentration of an analyte in a physiological fluid sample are described. More particularly, the present invention relates to techniques for distinguishing a signal caused by an extraneous event from a desired information providing signal such as one indicative of a measurement error.

摘要翻译： 描述了用于测量生理流体样品中分析物浓度的电化学测量技术。 更具体地，本发明涉及用于区分由外部事件引起的信号与期望的信息提供信号（例如表示测量误差的信号）的技术。

公开(公告)号：US08439837B2

公开(公告)日：2013-05-14

申请号：US11928560

申请日：2007-10-30

申请人： Sharbel E. Noujaim ,  David Horwitz ,  Manoj Sharma ,  Joseph Marhoul

发明人： Sharbel E. Noujaim ,  David Horwitz ,  Manoj Sharma ,  Joseph Marhoul

IPC分类号： A61B51/14532 ,  A61B51/14503

CPC分类号： A61B5/14532 ,  A61B5/746 ,  G06F19/00

摘要： The present invention is directed to a method of reducing false readings in a hypoglycemic detector that includes establishing a predetermined hypoglycemic threshold, a predetermined critical threshold, a predetermined rate of change in glucose concentration where the predetermined critical threshold is below the predetermined hypoglycemic threshold. A first sampling rate is then calculated based upon said predetermined hypoglycemic threshold, said predetermined critical threshold, and said predetermined rate of change in glucose concentration.

摘要翻译： 本发明涉及减少低血糖检测器中的错误读数的方法，其包括建立预定的低血糖阈值，预定临界阈值，预定临界阈值低于预定低血糖阈值的葡萄糖浓度的预定变化率。 然后基于所述预定的低血糖阈值，所述预定临界阈值和所述预定的葡萄糖浓度变化率来计算第一采样率。

公开(公告)号：US08404102B2

公开(公告)日：2013-03-26

申请号：US12829599

申请日：2010-07-02

申请人： Sherry Guo ,  Alastair M. Hodges ,  Ronald C. Chatelier ,  Bin Zhang

发明人： Sherry Guo ,  Alastair M. Hodges ,  Ronald C. Chatelier ,  Bin Zhang

IPC分类号： G01N27/327 ,  G01N27/26

CPC分类号： A61B5/14532 ,  A61B5/1486 ,  A61B2562/0295 ,  G01N27/3273

摘要： Methods and apparatus for electrochemically determining an analyte concentration value in a physiological sample are disclosed. The methods include using a test strip in which two time-current transients are measured by a meter electrically connected to an electrochemical test strip. Integrative current values are derived from the time-current transients and used in the calculation of analyte concentration.

摘要翻译： 公开了用于电化学测定生理样品中分析物浓度值的方法和装置。 这些方法包括使用测试条，其中通过电连接到电化学测试条的仪表测量两个时间电流瞬变。 积分电流值来自时间 - 电流瞬变，并用于计算分析物浓度。

公开(公告)号：US20130002266A1

公开(公告)日：2013-01-03

申请号：US13170947

申请日：2011-06-28

申请人： Ulrich KRAFT

发明人： Ulrich KRAFT

IPC分类号： G01R29/26

CPC分类号： A61B5/14532 ,  A61B2560/0242 ,  A61B2562/0295 ,  A61B2562/18 ,  G01N33/48785

摘要： A hand-held test meter for use with an analytical test strip in the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) includes a housing, a test meter control circuit block, and an electromagnetic interference detection circuit block with an antenna configured to sense electromagnetic fields of a predetermined frequency. The electromagnetic interference detection circuit block is configured to generate a signal representative of an electromagnetic field sensed by the antenna and to provide that signal to the test meter control circuit block. In addition, the test meter control circuit block is configured to interrupt operation of the hand-held test meter when the signal received from the electromagnetic interference detection circuit block is represents an electromagnetic field that interferes with the hand-held test meter's operation.

摘要翻译： 在测定体液样品（例如全血样品）中的分析物（例如葡萄糖）时，与分析测试条一起使用的手持式测试仪包括壳体，测试仪表控制电路块和 具有被配置为感测预定频率的电磁场的天线的电磁干扰检测电路块。 电磁干扰检测电路块被配置为产生表示由天线感测的电磁场的信号，并将该信号提供给测试仪控制电路块。 此外，当从电磁干扰检测电路块接收的信号表示干扰手持式测试仪的操作的电磁场时，测试仪表控制电路块被配置为中断手持式测试仪的操作。

公开(公告)号：US20130001103A1

公开(公告)日：2013-01-03

申请号：US13611703

申请日：2012-09-12

申请人： Ronald C. Chatelier ,  Alastair M. Hodges

发明人： Ronald C. Chatelier ,  Alastair M. Hodges

IPC分类号： G01N27/28

CPC分类号： C12Q1/001 ,  G01N27/3274 ,  G01N33/5438 ,  G01N33/96

摘要： Methods for distinguishing between an aqueous non-blood sample (e.g., a control solution) and a blood sample. In one aspect, the methods include using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or an aqueous non-blood sample based on at least two characteristics (e.g., amount of interferent present and reaction kinetics). The method can also include calculating a discrimination criteria based upon at least two characteristics. Various aspects of a system for distinguishing between blood samples and an aqueous non-blood sample are also provided herein.

摘要翻译： 用于区分水中非血液样品（例如对照溶液）和血液样品的方法。 在一个方面，所述方法包括使用测试条，其中通过电连接到电化学测试条的仪表测量多个电流瞬变。 基于至少两个特征（例如，存在的干扰物和反应动力学的量），使用电流瞬变来确定样品是血液样品还是水性非血液样品。 该方法还可以包括基于至少两个特征来计算鉴别标准。 本文还提供了用于区分血液样品和水性非血液样品的系统的各个方面。

公开(公告)号：US08313237B2

公开(公告)日：2012-11-20

申请号：US12603137

申请日：2009-10-21

申请人： Thomas Jetter ,  Klaus Neubert ,  Thomas M. Weber ,  Mahyar Z. Kermani

发明人： Thomas Jetter ,  Klaus Neubert ,  Thomas M. Weber ,  Mahyar Z. Kermani

IPC分类号： G01K3/00 ,  G01K13/00 ,  G01K7/00

CPC分类号： G01K13/00 ,  A61B5/14532 ,  G01K7/427 ,  G01N27/3274

摘要： The present invention is directed to, inter alia, systems and methods for calculating a temperature associated with an analyte measurement component of a biosensing instrument (such as a blood glucose monitor), with a test strip that is inserted in a biosensing instrument, or both. The present systems and methods may employ at least two temperature sensors, and the acquired temperature information may be used to modulate data regarding an analyte in a biological sample, thereby providing a more accurate measurement of the analyte.

摘要翻译： 本发明特别涉及用于计算与生物传感仪器（例如血糖监测器）的分析物测量部件相关联的温度的系统和方法，其中插入生物传感仪器中的测试条或两者 。 本系统和方法可以使用至少两个温度传感器，并且获取的温度信息可用于调制关于生物样品中的分析物的数据，从而提供对分析物的更精确的测量。

公开(公告)号：US08173008B2

公开(公告)日：2012-05-08

申请号：US12491026

申请日：2009-06-24

申请人： Koon-wah Leong

发明人： Koon-wah Leong

IPC分类号： G01N27/26 ,  G01N33/50

CPC分类号： G01N33/48771

摘要： A method for determining an analyte in a bodily fluid sample includes inserting the analyte test strip into a test meter. The insertion is such that an electrical connector pin of the test meter travels along an electrical contact pad of the analyte test strip, and across a meter identification feature disposed on the electrical contact pad, during the insertion. Moreover, during the insertion, a signal processing module of the test meter measures an electrical characteristic via the electrical connector pin as the electrical connector pin travels along the electrical contact pad and across the meter identification feature. The method also includes identifying the analyte test strip, using the signal processing module, based on the electrical characteristic measured as the analyte test strip is inserted into the test meter and, thereafter, applying the bodily fluid sample to the analyte test strip upon notification by the test meter that the identification indicates that such applying is appropriate. The method then includes determining an analyte in the bodily fluid sample using the test meter only if the identification indicates that such determining is appropriate. The electrical contact pad of the analyte test strip employed in the method has a predetermined contact electrical characteristic value and the meter identification feature of the analyte test strip has a predetermined identification feature electrical characteristic value that is dissimilar from the predetermined contact electrical characteristic, thus providing for identification of the analyte test strip by the test meter.

摘要翻译： 用于测定体液样品中的分析物的方法包括将分析物测试条插入测试仪中。 该插入使得测试仪的电连接器针沿着分析物测试条的电接触垫并且在插入期间跨越设置在电接触垫上的电表识别特征传播。 此外，在插入期间，随着电连接器引脚沿着电接触垫行进并跨越电表识别特征，测试仪的信号处理模块经由电连接器引脚测量电特性。 该方法还包括基于当分析物测试条插入到测试仪中时测量的电特性，使用信号处理模块来识别分析物测试条，然后在通过下述方式将体液样品施加到分析物测试条上： 该测试仪器的识别表明此类应用是合适的。 该方法然后包括使用测试仪器确定体液样品中的分析物，只要该识别指示该确定是合适的。 在该方法中使用的分析物测试条的电接触垫具有预定的接触电特性值，并且分析物测试条的仪表识别特征具有与预定接触电特性不相似的预定识别特征电特性值，从而提供 用于通过测试仪识别分析物测试条。