-
11.发明公开公开(公告)号：US20240317976A1
公开(公告)日：2024-09-26
申请号：US18610295
申请日：2024-03-20
Inventor： Lizhi XU , Hengjia ZHU , Zuochen WANG
CPC classification number: C08K9/04 , C08K3/22 , C08K7/02 , C08L29/04 , H01F1/445 , A61B34/73 , C08K2003/2275 , C08K2201/003 , C08K2201/01 , C08K2201/011 , C08L2205/16
Abstract: The present invention provides a class of magnetic hydrogels with tissue-mimetic mechanical properties and photothermal welding/healing capability. In these hydrogels, a hybrid network involving aramid nanofibers, functionalized Fe3O4 nanoparticles, and polyvinyl alcohol (PVA) is accomplished by a stepwise assembly of the functional components. The engineered interactions between nanoscale constituents enable facile materials processing and confer a combination of excellent mechanical properties, magnetism, water content and porosity.
-
12.发明公开公开(公告)号：US20240316557A1
公开(公告)日：2024-09-26
申请号：US18607538
申请日：2024-03-17
Inventor： Jingxuan TIAN , Ho Cheung SHUM , Aditi DEY POONAM , Lang NAN
CPC classification number: B01L3/502784 , B01L7/525 , B01L2200/0636 , B01L2200/0673 , B01L2200/147 , B01L2300/0883 , B01L2300/1822
Abstract: A portable, miniaturized microfluidic droplet-based digital polymerase chain reaction (PCR) device is provided. The device includes a droplet generation layer with a flow-focusing channel and multiple capillary channels, in which the flow-focusing channel has a flow focusing structure to generate droplets from a provided aqueous sample and extract oil, and the multiple capillary channels is configured to perform an oil extraction. An incubation layer includes heating plates, a microfluidic channel, and a container for conducting a PCR thermal cycling program. Controlled by a controller and powered by a power supplier, the PCR thermal cycling program involves maintaining predefined temperatures on each heating plate sequentially. This process ensures the heating of droplets to different temperatures at distinct times, facilitating precise and efficient PCR amplification.
-
公开(公告)号：US20240307427A1
公开(公告)日：2024-09-19
申请号：US18594986
申请日：2024-03-04
Inventor： Shing Fung Chow , Kam Hung Low , Si Nga Wong
IPC: A61K31/706 , A61K9/00 , A61K31/60
CPC classification number: A61K31/706 , A61K9/0075 , A61K31/60
Abstract: Provided is a cocrystals of remdesivir (RDV) composed of a 1:1 molar ratio of RDV and benzoic acid derivative. The benzoic acid derivative can be salicylic acid (SA). The RDV-SA cocrystal are formed by either liquid-assisted grinding or spray-drying, followed by thermal annealing to facilitate cocrystal formation. The RDV-SA cocrystals can be formulated as inhalable dry powders and included in a medicament for use in treatments for influenza viral infections, such as COVID-19. The inhalable RDV-SA cocrystal dry powders is suitable for deep lung delivery, with good dissolution performance.
-
Patent Agency Ranking
公开(公告)号：US20230194412A1
公开(公告)日：2023-06-22
申请号：US18082739
申请日：2022-12-16
Inventor： Kenneth Kin Yip WONG , Jiawei SHI , Mingsheng LI , Jiqiang KANG
IPC: G01N21/17 , H01S3/067 , H01S3/10 , H01S3/094 , H01S3/00 , H01S3/16 , H01S3/108 , G02F1/39 , H01S3/23 , H03F3/19 , G01N33/483
CPC classification number: G01N21/1702 , H01S3/06716 , H01S3/10038 , H01S3/094015 , H01S3/06791 , H01S3/1003 , H01S3/005 , H01S3/1608 , H01S3/1083 , G02F1/395 , H01S3/1616 , H01S3/2316 , H03F3/19 , G01N33/4833 , H03F2200/451 , H03F2200/294 , G01N2201/06113 , G01N2201/08 , G01N2201/0633 , G01N2201/103 , G01N2021/1706
Abstract: An optical-resolution photoacoustic microscopy (OR-PAM) system for visualizing water content deep in biological tissue uses an all-fiber 1930-nm hybrid optical parametrically-oscillating emitter. The emitter includes a tunable laser source whose output is amplified by a first erbium-doped fiber amplifier (EDFA). The output of the first amplifier is modulated with a Mach-Zehnder amplitude modulator that receives an RF signal with a nanosecond pulse width and a multiple kilohertz repetition rate. A second EDFA further amplifies the signal and passes it to a fiber circulator that in turn delivers it to a 1950/1550 mm fiber wavelength-division-multiplexing coupler WDM. The coupler introduces the signal to a cavity that includes a spool of highly nonlinear fiber and a Thulium-doped fiber amplifier TDFA. From the TDFA the signal reaches a 50/50 fiber coupler that sends part to a second output TDFA and guides part back to the cavity through a port of the WDM.
-
公开(公告)号：US20250101487A1
公开(公告)日：2025-03-27
申请号：US18472228
申请日：2023-09-22
Applicant: The University of Hong Kong , Advanced Biomedical Instrumentation Centre Limited , Centre for Virology, Vaccinology and Therapeutics Limited
Inventor： Sammer Ul HASSAN , Ho Cheung SHUM , Kai-Wang Kelvin TO , Ka Hei WAT
Abstract: The present invention relates to a SDFAST (Self Dilution for Faster Antimicrobial Susceptibility Testing), which is a microfluidic device that can perform self-dilution and does not require any pumps or valves to accomplish multiplexed microfluidic processes. SDFAST is designed using AutoCAD and fabricated using micro-milling machine. It consists of two polymethyl methacrylate (PMMA) rectangular plates which are in contact throughout the operation. The first plate is the bottom one that serves as lines of wells. The second plate is the top one that acts as a lid and seals the system. The second plate has complementary designs that echo the wells in the first plate, which allows fluidic channels to be formed.
-
16.发明公开公开(公告)号：US20240270916A1
公开(公告)日：2024-08-15
申请号：US18169722
申请日：2023-02-15
Inventor： Lizhi XU , Hegeng LI , Hongzhen Liu , Huimin HE , Zuochen WANG
CPC classification number: C08J9/0061 , C08J9/28 , C08J2201/0502 , C08J2205/044 , C08J2205/10 , C08J2329/04 , C08J2377/10 , C08J2429/04 , C08J2477/10 , H01L21/768
Abstract: A composite nanofiber aerogel (CNA) is formed from aramid nanofibers (ANFs) combined with polyvinyl alcohol (PVA). These nanoscale constituents of the aerogel form 3D networks with high nodal connectivity and strongly welded connectivity joints between fibrils so that the structure has high stiffness and strength compared to other polymeric aerogels and successive breakage of crosslinks at the connectivity nodes affords energy dissipation while maintaining the overall structural integrity. A specific class of CNA with a specific solid content may be used to form a thin firm with a composite nanofiber framework (CNFF) that is useful in the manufacture of kirigami wearable electronics.
-
公开(公告)号：US20240189907A1
公开(公告)日：2024-06-13
申请号：US18536120
申请日：2023-12-11
Inventor： Remi Rafael , Kwok Leung Chan
IPC: B22F10/18 , B22F10/20 , B29C64/118 , B29C64/194 , B29C64/371 , B33Y10/00 , B33Y30/00 , B33Y70/10
CPC classification number: B22F10/18 , B22F10/20 , B29C64/118 , B29C64/194 , B29C64/371 , B33Y10/00 , B33Y30/00 , B33Y70/10 , B29K2067/046
Abstract: A method for printing electronic components is based on the hybridization of Fused Deposition Modeling (FDM) and laser sintering. The method involves printing a layer of composite copper-based thermoplastic filament on a base. Then the filament is subjected to a laser beam so as to selectively remove the polymer matrix in a restricted area after printing to leave only the conductive particles forming a highly conductive network and sintering the conductive particles with the laser energy to reveal the conductive copper. Then, alternately repeating the printing and sintering steps on the filaments one on top of the other until a complete component of arbitrary geometry, including both insulative and conductive structures, is formed layer-by-layer.
-
18.发明公开公开(公告)号：US20240125774A1
公开(公告)日：2024-04-18
申请号：US18485856
申请日：2023-10-12
Inventor： Jingxuan Tian , Ho Cheung Shum , Yang Cao , Hao Yuan
IPC: G01N33/542
CPC classification number: G01N33/542
Abstract: A bioassay, which is a segregative phase separation system (SPSS) where a bioassay signal intensifier is presented. The bioassay signal intensifier is an aqueous two-phase system (ATPS) component that causes the signal to intensify in one aqueous phase of a plurality of phases formed from the bioassay composition. The source of the signal resulting from the inclusion of a test sample is selectively partitioned into one phase that can be of significantly lesser volume than in the bioassay absent the bioassay signal intensifier, such the signal's source is concentrated in that phase, and the signal is intensified.
-
-
-
-
-
-
-
Search Results
18
records
(took 0.017 seconds)
