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    Method of treating epidural lesions
    11.
    发明授权
    Method of treating epidural lesions 失效
    治疗硬膜外病变的方法

    公开(公告)号：US5215105A

    公开(公告)日：1993-06-01

    申请号：US436316

    申请日：1989-11-14

    申请人： Grigory Kizelshteyn ,  James E. Heavner ,  Edward I. McNamara ,  Kenneth J. Daignault, Jr.

    发明人： Grigory Kizelshteyn ,  James E. Heavner ,  Edward I. McNamara ,  Kenneth J. Daignault, Jr.

    IPC分类号： A61B1/313 ,  A61B17/34 ,  A61M29/02

    CPC分类号： A61B17/3401 ,  A61B1/3135 ,  A61M29/02

    摘要： A method for treating fibrotic lesions in the epidural space of the spinal column includes the steps of percutaneously inserting into the epidural space and across a fibrous lesion, a catheter carrying a compliant, inflatable balloon which is expandable both radially and longitudinally, and, expanding the balloon radially so as to contact the walls of the epidural space and disrupt the fibers of the lesion, and thereafter expanding the balloon longitudinally within the epidural space so as to increase the area of contact between the balloon and the walls of the epidural space. An introducer for percutaneously inserting a catheter or other medical device into the epidural space includes a polymeric tubular shaft having a tapered, curved distal tip through which the catheter is advanced and retracted.

    摘要翻译： 用于治疗脊柱硬膜外腔中的纤维化病变的方法包括以下步骤：经皮插入硬膜外腔并穿过纤维性病变，导管承载径向和纵向可扩张的顺应性，可充气气囊，以及扩张 使其与硬膜外腔的壁接触并破坏病变的纤维，然后在硬膜外腔内纵向膨胀气球，以增加气囊与硬膜外腔壁之间的接触面积。 用于将导管或其他医疗装置经皮插入硬膜外腔的导引器包括聚合物管状轴，其具有锥形的弯曲远端，导管通过该远端尖进和缩回。

    Endovascular stent and delivery system
    12.
    发明授权
    Endovascular stent and delivery system 失效
    血管内支架和输送系统

    公开(公告)号：US5100429A

    公开(公告)日：1992-03-31

    申请号：US424660

    申请日：1989-10-20

    申请人： Edward L. Sinofsky ,  Gary L. Boseck ,  Edward I. McNamara

    发明人： Edward L. Sinofsky ,  Gary L. Boseck ,  Edward I. McNamara

    IPC分类号： A61B17/00 ,  A61B17/03 ,  A61F2/92

    CPC分类号： A61F2/92 ,  A61F2/958 ,  A61B17/00491 ,  A61B2017/005 ,  A61B2017/00513 ,  A61B2017/00517 ,  A61F2/07 ,  A61F2220/0008 ,  A61F2220/005 ,  A61M2025/1013 ,  Y10S128/08

    摘要： An uncured or partially cured, collagen-based material is delivered to a selected site in a blood vessel and is crosslinked in the blood vessel by laser energy or other suitable energy to form an endovascular stent. The collagen-based material can be delivered to the blood vessel as a coating on an inflatable balloon mounted on the distal end of a catheter. The collagen-based material can also be delivered to the blood vessel in liquid form and forced through a porous balloon to form a tubular configuration. The collagen-based material is preferably crosslinked by laser radiation carried through an optical fiber to a diffusing tip located within the balloon. In another embodiment, an endovascular stent is formed by rolling a flexible sheet of biologically-compatible material onto an outside surface of an inflatable balloon. A crosslinkable collagen-based adhesive is used to adhere overlapping portions of the sheet together in the blood vessel and can be used to attach the stent to an inside surface of the blood vessel. The collagen-based adhesive is crosslinked in the blood vessel by application of laser energy or other suitable energy. A photodegradable adhesive can be used on an inside surface of the stent to releasably attach the stent to the inflatable balloon.

    摘要翻译： 将未固化或部分固化的基于胶原的材料输送到血管中的选定部位，并通过激光能量或其它合适的能量在血管中交联以形成血管内支架。 基于胶原的材料可以作为安装在导管远端的可充气球囊上的涂层递送到血管。 胶原基材料也可以以液体形式输送到血管并被迫穿过多孔气球以形成管状构型。 基于胶原的材料优选通过穿过光纤的激光辐射交联到位于气囊内的扩散尖端。 在另一个实施例中，通过将可生物相容的材料的柔性片材滚动到可充气球囊的外表面上而形成血管内支架。 使用可交联胶原基粘合剂将片材的重叠部分粘附在血管中，并且可用于将支架附着到血管的内表面。 胶原基粘合剂通过施加激光能量或其他合适的能量在血管中交联。 可以在支架的内表面上使用可光降解的粘合剂以将支架可释放地附接到可充气球囊。

    Hot tip device with optical diagnostic capability
    13.
    发明授权
    Hot tip device with optical diagnostic capability 失效
    具有光学诊断功能的尖端装置

    公开(公告)号：US5009655A

    公开(公告)日：1991-04-23

    申请号：US356437

    申请日：1989-05-24

    申请人： Kenneth J. Daignault, Jr. ,  Edward I. McNamara ,  Edward L. Sinofsky

    发明人： Kenneth J. Daignault, Jr. ,  Edward I. McNamara ,  Edward L. Sinofsky

    IPC分类号： G02B23/24 ,  A61B18/20 ,  A61B18/28 ,  A61N5/06 ,  H01S3/10 ,  H01S3/101

    CPC分类号： A61B18/28

    摘要： A hot tip device, typically used for melting and plowing through stenotic deposits in a coronary artery, is provided with optical diagnostic capabilities. The device includes an elongated, flexible member, a filter glass heating element attached to the distal end of the flexible member and an optical fiber extending through the flexible member and optically coupled to the heating element. The filter glass heating element absorbs a first range of wavelengths for heating and passes a second range of wavelengths for irradiating the artery through the filter glass heating element. In a preferred embodiment, the flexible member is a steerable guidewire, and the filter glass heating element is heated by infrared radiation. Ultraviolet or visible radiation is used to stimulate fluorescence from deposits in the artery.