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公开(公告)号：US20080183072A1
公开(公告)日：2008-07-31
申请号：US11664340
申请日：2007-03-30
申请人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
发明人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
IPC分类号： A61B5/05
CPC分类号： A61B5/1107 , A61B5/0031 , A61B5/686 , A61B8/12 , A61B8/488 , A61B8/56 , A61B2562/046 , A61N1/3627 , A61N1/365
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electro-mechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译： 提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。 在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。 使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。
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12.发明授权Systems, methods and apparatus for performing resection/ablation in a conductive medium 失效用于在导电介质中进行切除/消融的系统，方法和装置
公开(公告)号：US6113594A
公开(公告)日：2000-09-05
申请号：US678412
申请日：1996-07-02
申请人： George M. Savage
发明人： George M. Savage
CPC分类号： A61B18/149 , A61B18/1485 , A61B2018/00011 , A61B2018/00196 , A61B2018/00285 , A61B2018/00505 , A61B2018/00595 , A61B2018/00601 , A61B2018/1253 , A61B2018/126 , A61B2018/1412 , A61B2018/1472 , A61B2018/162 , A61B2018/1861 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： The invention provides methods, systems and apparatus for electrosurgically treating tissue particularly within the uterus and prostate. In an exemplary method, a surgical instrument comprising an elongate shaft having a proximal end and a distal end, an active electrode near the distal end, and a return electrode is introduced into the uterus. An electrically conductive fluid is then introduced into the uterus to distend the uterus and to form an electrically conductive path between the active electrode and the return electrode. The active electrode is then contacted against tissue within the body cavity. Current is passed between the active electrode and the return electrode while the active electrode is contacting the tissue. The active electrode is provided with a surface area which is selected to produce a power density sufficient to resect or coagulate tissue. The active electrode is then moved along and through the tissue to remove, coagulate or vaporize the tissue.
摘要翻译： 本发明提供了用于电疗治疗组织的方法，系统和装置，特别是在子宫和前列腺内。 在示例性方法中，包括具有近端和远端的细长轴，远端附近的活性电极和返回电极的外科器械引入到子宫中。 然后将导电流体引入子宫以扩张子宫，并在活性电极和返回电极之间形成导电路径。 然后将活性电极与体腔内的组织接触。 当活性电极与组织接触时，电流在有源电极和返回电极之间通过。 有源电极具有被选择以产生足以切除或凝结组织的功率密度的表面积。 然后，活性电极沿着并穿过组织移动，以去除，凝结或蒸发组织。
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公开(公告)号：US08121687B2
公开(公告)日：2012-02-21
申请号：US11718201
申请日：2005-10-31
申请人： Marc Jensen , Todd Thompson , Olivier Colliou , George M. Savage , Mark J. Zdeblick , Jeremy Frank , Lawrence W. Arne , Robert White
发明人： Marc Jensen , Todd Thompson , Olivier Colliou , George M. Savage , Mark J. Zdeblick , Jeremy Frank , Lawrence W. Arne , Robert White
IPC分类号： A61N1/18
CPC分类号： A61N1/056 , A61B5/1107 , A61B5/6851 , A61B5/6857 , A61B5/6858 , A61B5/686 , A61B2562/0266 , A61N1/08 , A61N1/3627
摘要： Methods for evaluating motion of a cardiac tissue location, e.g., heart wall, are provided. In the subject methods, timing of a signal obtain from a strain gauge stably associated with the tissue location of interest is employed to evaluate movement of the cardiac tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译： 提供了用于评估心脏组织位置例如心脏壁的运动的方法。 在本方法中，采用从与感兴趣的组织位置稳定相关联的应变仪获得的信号的定时来评估心脏组织位置的运动。 还提供了用于实践主题方法的系统，装置和相关组合物。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。
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公开(公告)号：US20080306394A1
公开(公告)日：2008-12-11
申请号：US12063097
申请日：2006-08-09
IPC分类号： A61B5/04
CPC分类号： A61B5/04011
摘要： A method for measuring the conduction velocity of a depolarization wave in a tissue employs a first satellite located within the tissue and a second that satellite is located within the tissue a distance away from the first satellite, e.g., by using the time of depolarization wave as reported from each satellite and the distance to determine velocity of the wave. Also provided are systems and kits that find use in accordance with the invention.
摘要翻译： 用于测量组织中去极化波的传导速度的方法使用位于组织内的第一卫星，并且第二卫星位于组织内距离第一卫星一定距离，例如通过使用去极化波的时间 报道从每颗卫星和距离来确定波的速度。 还提供了根据本发明使用的系统和试剂盒。
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15.发明申请Automated Optimization of Multi-Electrode Pacing for Cardiac Resynchronization 有权用于心脏再同步的多电极起搏的自动优化公开(公告)号：US20080294218A1
公开(公告)日：2008-11-27
申请号：US11909786
申请日：2006-03-31
申请人： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
发明人： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
IPC分类号： A61N1/06
CPC分类号： A61N1/3627 , A61N1/08 , A61N1/36185 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/3686 , A61N1/37247
摘要： One embodiment of the present invention provides a system for automatically optimizing CRT procedures using a multi-electrode pacing lead. During operation, the system performs a first set of iterations to select one or more satellites on one or more pacing leads inserted in a patient. A pacing lead includes a plurality of pacing satellites, and a pacing satellite includes a plurality of electrodes that can be individually addressed and used for transmitting or detecting electric signals. The system then performs a second set of iterations to select one or more electrodes on the selected satellites. The system further performs a third set of iterations to select one or more timing configurations for pacing signals transmitted through one or more of the selected electrodes.
摘要翻译： 本发明的一个实施例提供一种用于使用多电极起搏引线自动优化CRT程序的系统。 在操作期间，系统执行第一组迭代以在插入患者体内的一个或多个起搏引线上选择一个或多个卫星。 起搏引线包括多个起搏卫星，并且起搏卫星包括多个电极，其可单独寻址并用于发送或检测电信号。 然后，系统执行第二组迭代以选择所选卫星上的一个或多个电极。 该系统进一步执行第三组迭代以选择一个或多个定时配置，用于通过一个或多个所选择的电极发射的起搏信号。
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公开(公告)号：US6039748A
公开(公告)日：2000-03-21
申请号：US906358
申请日：1997-08-05
CPC分类号： A61B17/3498 , A61B17/32002 , A61B17/29 , A61B17/295 , A61B17/32053 , A61B17/3462 , A61B17/3496 , A61B2017/00353 , A61B2017/320024 , A61B2017/320775 , A61B2090/08021
摘要： A morcellator for removing large masses of tissues during laparoscopic procedures includes a rotationally fixed, axially movable inner tube disposed within a rotating cutting member. The cutting member is often disposed in the annular space between the inner tube and an outer tube. A laparoscopic grasping instrument is inserted through the lumen and draws the tissue proximally through the morcellator. As the cutting member severs tissue, the tissue is drawn into the fixed lumen of the inner tube. This prevents the cutting member from twisting the severed tissue, thereby preventing any degradation of the surgeon's control. A novel valve is provided to prevent loss of insufflation gas when no instrument traverses the lumen. The inner tube can be translated distally to protect tissues and/or other surgical implements against inadvertent contact with the cutting edge of the cutting member.
摘要翻译： 用于在腹腔镜手术过程中去除大块组织的分离器包括设置在旋转切割构件内的旋转固定的可轴向移动的内管。 切割构件通常设置在内管和外管之间的环形空间中。 将腹腔镜手术器械通过内腔插入并通过手术器向近侧抽出组织。 当切割构件切断组织时，组织被拉入内管的固定内腔。 这防止切割构件扭转被切断的组织，从而防止外科医生的控制的任何劣化。 提供了一种新颖的阀门，用于在没有仪器穿过管腔时防止吹入气体的损失。 内管可以向远侧平移以保护组织和/或其他外科手术器免于与切割构件的切割边缘的意外接触。
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公开(公告)号：US6032673A
公开(公告)日：2000-03-07
申请号：US912259
申请日：1997-08-15
CPC分类号： A61B18/1485 , A61B17/32 , A61B18/149 , A61B2018/00196 , A61B2018/00208 , A61B2018/00559 , A61B2018/00577 , A61B2018/00601 , A61B2018/00738 , A61B2018/00982 , A61B2018/1253 , A61B2018/1407 , A61B2018/1861 , A61B2090/064 , A61B2090/3614 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： The present invention provides a tissue resection device comprising a handle housing having a fluid infusion lumen. A shaft is reciprocatably mounted to the housing, the shaft having an aperture adjacent to a distal end and a fluid and tissue aspiration lumen extending from the aperture to a proximal end of the shaft. A cutting member is disposed adjacent to the aperture to sever tissue as the shaft is reciprocated, and an imaging mechanism on the housing is oriented toward the cutting member, thereby allowing the attending surgeon to optically direct the removal of body cavity tissue. A chopping mechanism is disposed within the lumen of the shaft to reduce the size of tissues passing through the lumen.
摘要翻译： 本发明提供一种组织切除装置，其包括具有流体输注腔的手柄壳体。 轴可往复运动地安装到壳体，该轴具有邻近远端的孔和从孔的远端延伸到轴的近端的流体和组织抽吸腔。 当所述轴往复运动时，切割构件邻近所述孔布置以切断组织，并且所述壳体上的成像机构朝向所述切割构件，从而允许所述外科医生光学地引导体腔组织的移除。 切割机构设置在轴的内腔内以减小穿过管腔的组织的尺寸。
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公开(公告)号：US08956287B2
公开(公告)日：2015-02-17
申请号：US12299303
申请日：2007-05-02
IPC分类号： G06Q50/00 , A61B5/00 , A61B5/07 , H01M8/02 , G06Q10/00 , G06Q50/22 , G06F19/00 , H04B13/00 , H01M8/00
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/0028 , A61B5/073 , A61B5/4833 , A61B5/4848 , G06F19/00 , G06F19/34 , G06F19/3418 , G06F19/345 , G06F19/3475 , G06Q10/00 , G06Q50/22 , G16H50/20 , H01M8/02 , H01M2220/10 , H04B13/005 , Y10S128/903 , Y10S128/92
摘要： Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.
摘要翻译： 提供了允许根据患者定制的治疗方案治疗患者的方法，系统和组合物。 本发明的实施方案包括从患者获得剂量给药信息并使用它来定制患者的治疗方案。 本发明的实施方案还包括基于定制的治疗方案制备并转发患者物理药物剂量。
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公开(公告)号：US07983751B2
公开(公告)日：2011-07-19
申请号：US12063097
申请日：2006-08-09
IPC分类号： A61N1/00
CPC分类号： A61B5/04011
摘要： A method for measuring the conduction velocity of a depolarization wave in a tissue employs a first satellite located within the tissue and a second that satellite is located within the tissue a distance away from the first satellite, e.g., by using the time of depolarization wave as reported from each satellite and the distance to determine velocity of the wave. Also provided are systems and kits that find use in accordance with the invention.
摘要翻译： 用于测量组织中去极化波的传导速度的方法使用位于组织内的第一卫星，并且第二卫星位于组织内距离第一卫星一定距离，例如通过使用去极化波的时间作为 报道从每颗卫星和距离来确定波的速度。 还提供了根据本发明使用的系统和试剂盒。
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公开(公告)号：US20110172521A1
公开(公告)日：2011-07-14
申请号：US13069223
申请日：2011-03-22
申请人： Mark ZDEBLICK , George M. SAVAGE
发明人： Mark ZDEBLICK , George M. SAVAGE
IPC分类号： A61B5/05
CPC分类号： A61N1/36528 , A61B5/05 , A61B5/1107
摘要： The inventive implantable Doppler tomography system allows, for the first time, the use of Doppler shift for purposes of tracking cardiac wall motion. The present inventive Doppler tomography system methods and devices provide a critical new tool in the physician's armamentarium which provides accurate, real time monitoring of the mechanical performance of the heart.
摘要翻译： 本发明的可植入多普勒层析成像系统首次允许使用多普勒频移来跟踪心脏壁运动。 本发明的多普勒层析成像系统方法和装置在医师装置中提供关键的新工具，其提供对心脏的机械性能的准确的实时监测。
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