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公开(公告)号：US5287681A
公开(公告)日：1994-02-22
申请号：US4887
申请日：1993-01-19
Applicant: Geoffrey W. Vernon , James Goodwin
Inventor： Geoffrey W. Vernon , James Goodwin
CPC classification number: B29C66/83413 , B29C53/50 , B29C65/18 , B29C65/305 , B29C65/7835 , B29C65/7894 , B29C66/1122 , B29C66/4322 , B29C66/49 , B29C66/876 , B29C66/91212 , B29C66/91231 , B29C66/9161 , B65B29/02 , B65B51/16 , B65B9/067 , B29C66/91421 , B29C66/961 , B65B2009/063
Abstract: A flexible heat-sealable web is shaped continuously into a tubular cross-sectional shape, e.g. as an intermediate stage in the production of infusion bags comprising severed and sealed lengths of the tubular shape. The web is drawn along a shaped shoe and side margins of the web are folded over opposite sides of the shoe by rollers and fingers to place the opposite side edges of the web in overlapping relationship against the shoe. The overlapped edges pass between a roller mounted in the shoe and an external heated roller to be pressed between the two rollers in order to lap weld the edges together as the web travels along the shoe. The shoe continues to form the web downstream of the welding station into a flattened tube.
Abstract translation: 柔性可热封的网状物连续地成形为管状横截面形状，例如， 作为生产包括管状形状的切断和密封长度的输液袋的中间阶段。 幅材沿着成形的靴子被拉伸，并且纸幅的侧边缘通过辊和手指折叠在鞋的相对侧上，以使幅材的相对侧边缘与鞋子重叠。 重叠的边缘通过安装在鞋中的辊和被压在两个辊之间的外部加热辊，以便当织物沿鞋移动时将边缘焊接在一起。 鞋子继续在焊接站下游形成一个扁平的管子。
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12.发明授权Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation 有权用于分析CYP3A4细胞色素P450基因调控的转基因动物公开(公告)号：US08088968B2
公开(公告)日：2012-01-03
申请号：US12463246
申请日：2009-05-08
Applicant: Christopher Liddle , Bryan James Goodwin , Graham Robertson
Inventor： Christopher Liddle , Bryan James Goodwin , Graham Robertson
IPC: G01N33/00 , A01K67/00 , A01K67/027 , C12N5/00 , C12N15/11
CPC classification number: C12N15/8509 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2267/03 , A01K2267/0393 , A61K49/0008 , C12N9/0077
Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human.
Abstract translation: 本发明涉及产生非人转基因动物，其包含用于产生可检测量的报告分子的报道构建体，所述报道分子可操作地连接于来自位于基因转录位点的起始点之间的人CYP3A4基因的转录调节核酸分子，和 位于位于该位点上游13,000个核苷酸的位置。 本发明还涉及这些动物用于测定化合物，特别是但不排除地，异生物或类固醇对人类CYP3A4基因表达调节的影响的用途。
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13.发明申请COMPOSITIONS AND METHODS FOR FUNCTIONALIZING OR CROSSLINKING LIGANDS ON NANOPARTICLE SURFACES 审中-公开在纳米级表面上功能化或交联配体的组合物和方法公开(公告)号：US20110226995A1
公开(公告)日：2011-09-22
申请号：US13120335
申请日：2009-10-02
Applicant: Eric Tulsky , Wenxi Huang , James Goodwin , Weiwen Zhao
Inventor： Eric Tulsky , Wenxi Huang , James Goodwin , Weiwen Zhao
CPC classification number: G01N33/588 , B82Y15/00 , G01N33/54353 , G01N33/587
Abstract: This disclosure provides novel ways to modify/functionalize, including crosslink, ligands in the surface coating or molecules in other coatings on a nanoparticle, by using radical addition reactions to add a reactant group onto a ligand/molecule of a nanoparticle. Examples include using a functionalized benzophenone that can be attached or crosslinked to a ligand in the surface coating of a nanocrystal by photochemically-initiated radical addition.
Abstract translation: 本公开提供了通过使用自由基加成反应将反应物基团添加到纳米颗粒的配体/分子上来修饰/官能化包括交联在表面涂层中的配体或纳米颗粒上其它涂层中的分子的新方法。 实例包括使用可以通过光化学引发的自由基加成在纳米晶体的表面涂层中与配体连接或交联的官能化二苯甲酮。
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公开(公告)号：US20100146652A1
公开(公告)日：2010-06-10
申请号：US12629186
申请日：2009-12-02
Applicant: Christopher LIDDLE , Bryan James Goodwin
Inventor： Christopher LIDDLE , Bryan James Goodwin
CPC classification number: C12Q1/6897 , A01K2267/0393
Abstract: An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.
Abstract translation: 包含编码细胞色素P450（P450）CYP3A4产生或表达的转录增强子的核苷酸序列的分离的核酸分子，以及核酸分子用于筛选细胞和动物中CYP3A4表达的异种生物诱导化合物的用途。
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公开(公告)号：US07505455B1
公开(公告)日：2009-03-17
申请号：US09273238
申请日：1999-03-19
Applicant: James Goodwin , Joseph Meza , David Zalatimo
Inventor： James Goodwin , Joseph Meza , David Zalatimo
IPC: H04L12/28
CPC classification number: H04L12/40052
Abstract: A system is described having a network, a bus and an interface coupling the network to the bus. A host is coupled to the network and executes software to generate packets for communication on the network. A bus device is coupled to the bus. The interface and host coordinate to transport bus device packets between the host and the bus device via tunneling over the network.
Abstract translation: 描述了一种具有网络，总线和将网络耦合到总线的接口的系统。 主机耦合到网络并执行软件以产生用于在网络上进行通信的分组。 总线设备耦合到总线。 接口和主机坐标通过网络隧道传输主机和总线设备之间的总线设备数据包。
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Patent Agency Ranking
公开(公告)号：US07455892B2
公开(公告)日：2008-11-25
申请号：US10381690
申请日：2001-09-25
Applicant: Andrew James Goodwin , Luke Ward , Patrick Merlin , Jas Pal Singh Badyal
Inventor： Andrew James Goodwin , Luke Ward , Patrick Merlin , Jas Pal Singh Badyal
CPC classification number: B05D1/62 , B05B5/00 , B05B17/0623 , B05D1/10 , C23C16/4486 , C23C16/503 , H05H1/2475 , H05H2001/2481 , H05H2240/10
Abstract: A method for forming a coating on a substrate using an atmospheric pressure plasma discharge. The method comprises introducing an atomized liquid and/or solid coating-forming material into an atmospheric pressure plasma discharge and/or an ionized gas stream resulting therefrom, and exposing the substrate to the atomized coating-forming material. The application also described a method for polymerizing a polymer forming material, and further to apparatus for forming a coating on a substrate.
Abstract translation: 使用大气压等离子体放电在基板上形成涂层的方法。 该方法包括将雾化的液体和/或固体涂层形成材料引入到由其产生的大气压等离子体放电和/或电离气流中，并将基底暴露于雾化涂层形成材料。 本申请还描述了聚合物形成材料的聚合方法，还描述了在基材上形成涂层的装置。
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公开(公告)号：US20080227864A1
公开(公告)日：2008-09-18
申请号：US10598338
申请日：2005-02-23
Applicant: Bryan James Goodwin , Eugene Lee Stewart , Peter Jonathan Brown , Philippe Delerive
Inventor： Bryan James Goodwin , Eugene Lee Stewart , Peter Jonathan Brown , Philippe Delerive
IPC: A61K31/136 , A61P3/00 , A61P9/00
CPC classification number: A61K31/136
Abstract: Methods or prevention or treatment of diseases or conditions caused by low plasma apoA-1 levels, the use of LRH1 activators in such methods and methods for identification of compounds useful in such treatment.
Abstract translation: 方法或预防或治疗由低血浆apoA-1水平引起的疾病或病症，LRH1激活剂在这些方法中的应用和方法用于鉴定可用于此类治疗的化合物。
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公开(公告)号：US07349391B2
公开(公告)日：2008-03-25
申请号：US09272807
申请日：1999-03-19
Applicant: Avner Ben-Dor , James Goodwin , Joseph Meza , Mark S. Young , David Zalatimo
Inventor： Avner Ben-Dor , James Goodwin , Joseph Meza , Mark S. Young , David Zalatimo
CPC classification number: H04L12/40123 , H04L12/4633 , H04L12/6418 , H04L29/06 , H04L69/16 , H04L69/169 , H04L2012/6472
Abstract: A system is described having a network, a bus and an interface coupling the network to the bus. A host is coupled to the network and executes software to generate packets for communication on the network. A bus device is coupled to the bus. The interface and host coordinate to transport bus device packets between the host and the bus device via tunneling over the network.
Abstract translation: 描述了一种具有网络，总线和将网络耦合到总线的接口的系统。 主机耦合到网络并执行软件以生成用于在网络上进行通信的分组。 总线设备耦合到总线。 接口和主机坐标通过网络隧道传输主机和总线设备之间的总线设备数据包。
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公开(公告)号：US20060159812A1
公开(公告)日：2006-07-20
申请号：US11219588
申请日：2005-09-01
Applicant: James Goodwin , Andres Del Rosal , Ricardo Henriquez , Gilberto Garcia , Salvador Lopez
Inventor： James Goodwin , Andres Del Rosal , Ricardo Henriquez , Gilberto Garcia , Salvador Lopez
IPC: C12H1/04
Abstract: The present invention relates to methods for making an alcoholic beverage. In particular, the invention relates to methods for making an alcoholic beverage comprising distilling a first portion of an alcoholic mixture to provide a first distillate; distilling a second portion of the alcoholic mixture under conditions sufficient to provide a second distillate having a composition different from the first distillate; and admixing at least a portion of the first distillate and at least a portion of the second distillate to make a first blend. The first blend may optionally be aged, proof-adjusted, sparged with gas, and/or filtered to provide an alcoholic beverage. In one embodiment, the alcoholic beverage is tequila.
Abstract translation: 本发明涉及制造酒精饮料的方法。 特别地，本发明涉及制备含酒精饮料的方法，包括蒸馏第一部分醇混合物以提供第一馏出物; 在足以提供具有不同于第一馏出物的组成的第二馏出物的条件下蒸馏第二部分醇混合物; 以及混合所述第一馏出物和所述第二馏出物的至少一部分的至少一部分以制备第一共混物。 第一混合物可以任选地老化，校正调整，用气体喷射和/或过滤以提供酒精饮料。 在一个实施方案中，酒精饮料是龙舌兰酒。
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公开(公告)号：US06984489B1
公开(公告)日：2006-01-10
申请号：US09700991
申请日：1999-05-20
Applicant: Christopher Liddle , Bryan James Goodwin
Inventor： Christopher Liddle , Bryan James Goodwin
CPC classification number: C12Q1/6897 , A01K2267/0393
Abstract: An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression is disclosed, as are uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.
Abstract translation: 公开了包含编码细胞色素P450（P450）CYP3A4产生或表达的转录增强子的核苷酸序列的分离的核酸分子，核酸分子用于筛选细胞和动物中CYP3A4表达的异种生物诱导化合物的用途。
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