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    Non-invasive screening of skin diseases by visible/near-infrared spectroscopy
    13.
    发明授权
    Non-invasive screening of skin diseases by visible/near-infrared spectroscopy 有权
    通过可见/近红外光谱对皮肤疾病进行非侵入性筛查

    公开(公告)号：US07280866B1

    公开(公告)日：2007-10-09

    申请号：US10089314

    申请日：2000-10-05

    申请人： Laura M. McIntosh ,  Michael Jackson ,  Henry Mantsch, II ,  James R. Mansfield ,  A. Neil Crowson ,  John W. P. Toole

    发明人： Laura M. McIntosh ,  Michael Jackson ,  Henry Mantsch, II ,  James R. Mansfield ,  A. Neil Crowson ,  John W. P. Toole

    IPC分类号： A61B5/00

    CPC分类号： A61B5/445 ,  A61B5/0075 ,  A61B5/444 ,  A61B5/7264 ,  G01N21/31 ,  G01N21/359 ,  G01N2021/3155 ,  G01N2201/129

    摘要： A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible/near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spectra (400-2500 nm) of skin neoplasms (actinic keratoses, basal cell carcinomata, banal common acquired melanocytic nevi, dysplastic melanocytic nevi, actinic lentigines and seborrheic keratoses) were collected by placing a fiber optic probe on the skin. Paired t-tests, repeated measures analysis of variance and linear discriminant analysis were used to determine whether significant spectral differences existed and whether spectra could be classified according to lesion type. Paired t-tests showed significant differences (p

    摘要翻译： 用于皮肤疾病诊断的非侵入性工具将是一种有用的临床辅助手段。 这项研究的目的是确定是否可以使用可见/近红外光谱来非侵入性地表征皮肤疾病。 通过放置光学纤维素收集体内可见光和近红外光谱（400-2500nm）的皮肤肿瘤（光化性角化病，基底细胞癌，平凡的获得性黑素细胞痣，发育不良的黑素细胞痣，光化性斑点和脂溢性角化病） 探测皮肤。 配对t检验，重复测量方差分析和线性判别分析用于确定是否存在显着的光谱差异，以及是否可以根据病变类型对光谱进行分类。 配对t检验显示在可见/近红外光谱的几个区域的正常皮肤和皮肤损伤之间显着差异（p <0.05）。 此外，通过方差分析发现病变组之间存在显着差异。 线性判别分析将良性病变的光谱与恶性或恶性病变相比较，准确度高。 可见/近红外光谱仪是用于筛选皮肤疾病的有希望的非侵入性技术。

    Chlorine free and reduced chlorine content polymer and resin compositions for adhesion to plastics
    14.
    发明申请
    Chlorine free and reduced chlorine content polymer and resin compositions for adhesion to plastics 审中-公开
    无氯和还原氯含量的聚合物和树脂组合物用于粘合塑料

    公开(公告)号：US20070123649A1

    公开(公告)日：2007-05-31

    申请号：US11699159

    申请日：2007-01-29

    申请人： Michael Jackson ,  Frank Stubbs ,  Joseph Mecozzi ,  Dean Smith ,  Hans Neubeck ,  David Rybarczyk ,  Kevin Smith ,  Rene Hoffman

    发明人： Michael Jackson ,  Frank Stubbs ,  Joseph Mecozzi ,  Dean Smith ,  Hans Neubeck ,  David Rybarczyk ,  Kevin Smith ,  Rene Hoffman

    IPC分类号： C08L51/00

    CPC分类号： C09D151/06 ,  C08F255/00 ,  C08F255/02 ,  C08L25/04 ,  C08L33/00 ,  C08L33/066 ,  C08L33/08 ,  C08L51/06 ,  C08L63/00 ,  C08L67/00 ,  C08L75/00 ,  C08L77/00 ,  C08L2666/02 ,  C09D133/066 ,  C09D133/08 ,  C09J151/06

    摘要： The present invention provides a composition comprising one or more than one isotactic, modified polypropylene (MPP) or polypropylene-α-olefin copolymer (MPP copolymer) and one or more than one polymer or resin, wherein said MPP or MPP copolymer is modified with one or more than one carboxyl or anhydride, preferably maleic acid or anhydride, or with one or more than one epoxy or hydroxyl group. Alternatively, the present invention provides a composition comprising an adduct which is the reaction product of one or more than one isotactic, modified polypropylene (MPP) or isotactic, modified polypropylene-α-olefin copolymer (MPP copolymer) with one or more than one carboxyl, anhydride, epoxy or hydroxyl functional reactant, polymer or resin. The composition may be used to make aqueous or solvent borne compositions for making primers, coatings, powder coatings, films, laminates, moldings and shaped-articles having good adhesion to thermoplastic polyolefins (TPO) or polyolefin, while partly or wholly avoiding use of environmentally harmful chlorinated polyolefin (CPO) additives. The isotactic MPP or MPP copolymer preferably has one or two terminal carboxyl, anhydride, epoxy or hydroxyl group. More preferably, the isotactic MPP or MPP copolymer has a low molecular weight and a melting point of from 70 to 145° C., preferably 80 to 105° C. for MPP copolymer and preferably 105 to 120° C. for an MPP homopolymer, and provides excellent penetration into TPO or polyolefin substrates.

    摘要翻译： 本发明提供了包含一种或多种全同立构改性聚丙烯（MPP）或聚丙烯-α-烯烃共聚物（MPP共聚物）和一种或多种聚合物或树脂的组合物，其中所述MPP或MPP共聚物用一种 或多于一个羧基或酸酐，优选马来酸或酸酐，或与一个或多于一个环氧基或羟基。 或者，本发明提供一种组合物，其包含加合物，其为一种或多于一种全同立构改性聚丙烯（MPP）或全同立构改性聚丙烯-α-烯烃共聚物（MPP共聚物）与一种或多于一种羧基的反应产物 ，酸酐，环氧或羟基官能反应物，聚合物或树脂。 该组合物可用于制备具有与热塑性聚烯烃（TPO）或聚烯烃具有良好粘附性的底漆，涂料，粉末涂料，薄膜，层压材料，模塑制品和成型制品的水性或溶剂型组合物，同时部分或完全避免使用环境 有害氯化聚烯烃（CPO）添加剂。 全同立构MPP或MPP共聚物优选具有一个或两个末端羧基，酸酐，环氧基或羟基。 更优选地，全同立构MPP或MPP共聚物对于MPP共聚物具有低分子量和70〜145℃，优选80〜105℃的熔点，优选MPP均聚物为105〜120℃， 并提供优异的渗透TPO或聚烯烃基材。

    Inorganic/organic-filled styrenic thermoplastic door skins
    15.
    发明申请
    Inorganic/organic-filled styrenic thermoplastic door skins 审中-公开
    无机/有机填充的苯乙烯热塑性门皮

    公开(公告)号：US20070077405A1

    公开(公告)日：2007-04-05

    申请号：US11241496

    申请日：2005-09-30

    申请人： Michael Jackson

    发明人： Michael Jackson

    IPC分类号： B32B7/02

    CPC分类号： B32B27/08 ,  B32B27/065 ,  B32B27/20 ,  B32B27/302 ,  B32B27/308 ,  B32B27/365 ,  B32B2262/06 ,  B32B2262/067 ,  B32B2262/101 ,  B32B2262/106 ,  B32B2264/10 ,  B32B2264/101 ,  B32B2266/0278 ,  B32B2274/00 ,  B32B2307/536 ,  B32B2307/712 ,  B32B2307/734 ,  B32B2607/00 ,  E04C2/22 ,  Y10T428/24975

    摘要： An article comprising a frame having an outer periphery with a multilayered, substantially planar skin secured thereto that is exposed to various environmental conditions is disclosed. The skin comprises a first layer exposed to the environmental conditions and a second layer shielded from the environmental conditions by the first layer. The first layer is substantially free of organic and/or inorganic fillers and comprises a copolymer of at least one ethylenically unsaturated monomer, at least one aromatic vinyl compound, and at least one acrylic ester elastomer. The second layer comprises a terpolymer of at least one ethylenically unsaturated monomer, at least one butadiene, and at least one aromatic vinyl compound and has at least one filler is dispersed therein in an amount of from about 5 to about 35 percent based on a total weight of the second layer.

    摘要翻译： 公开了一种包括具有外周边的框架，该框架具有固定到其上的多层，基本平坦的表面，其暴露于各种环境条件。 皮肤包括暴露于环境条件的第一层和由第一层屏蔽环境条件的第二层。 第一层基本上不含有机和/或无机填料，并且包含至少一种烯属不饱和单体，至少一种芳族乙烯基化合物和至少一种丙烯酸酯弹性体的共聚物。 第二层包含至少一种烯键式不饱和单体，至少一种丁二烯和至少一种芳族乙烯基化合物的三元共聚物，并且至少一种填料以基于总量的约5至约35％的量分散在其中 第二层的重量。

    System and method for vertical flight planning
    18.
    发明申请
    System and method for vertical flight planning 有权
    垂直飞行计划的系统和方法

    公开(公告)号：US20050283281A1

    公开(公告)日：2005-12-22

    申请号：US10871668

    申请日：2004-06-21

    申请人： Gary Hartmann ,  Michael Jackson ,  Brian O'Laughlin ,  Richard Snyder ,  Rosa Weber

    发明人： Gary Hartmann ,  Michael Jackson ,  Brian O'Laughlin ,  Richard Snyder ,  Rosa Weber

    IPC分类号： G01C21/00 ,  G05D1/00 ,  G05D1/06

    CPC分类号： G05D1/0607 ,  G01C21/00

    摘要： A method for performing performance prediction with respect to a vertical flight plan. A system performs performance prediction with respect to a vertical flight plan of an aircraft that includes determining which vertical flight plan rules of a plurality of vertical flight rules that have been loaded in a predictions processor are active by monitoring for criteria that are used to initiate or terminate one or more of the vertical flight plan rules. Aircraft state is predicted at waypoints along a lateral flight path in view of active vertical flight plan rules, and the predicted aircraft state is updated within an integrated flight plan database that stores prediction performance data associated with the aircraft's flight.

    摘要翻译： 一种用于对垂直飞行计划进行性能预测的方法。 系统对飞行器的垂直飞行计划执行性能预测，其包括通过监视用于启动的标准来确定已经加载在预测处理器中的多个垂直飞行规则的哪些垂直飞行计划规则是活动的 终止一个或多个垂直飞行计划规则。 考虑到主动垂直飞行计划规则，沿着侧向飞行路径的航路点预测飞行器状态，并且在集成的飞行计划数据库内更新预测的飞行器状态，该飞行器状态存储与飞行器的飞行相关联的预测演奏数据。

    Nanoclay modified waterborne compositions for coating plastic and methods for making the same
    19.
    发明申请
    Nanoclay modified waterborne compositions for coating plastic and methods for making the same 审中-公开
    用于涂覆塑料的Nanoclay改性水性组合物及其制备方法

    公开(公告)号：US20050059765A1

    公开(公告)日：2005-03-17

    申请号：US10938029

    申请日：2004-09-10

    申请人： William Finch ,  Michael Jackson ,  Dennis Lorah ,  Darren Marsh ,  David Rybarczyk ,  Frank Stubbs

    发明人： William Finch ,  Michael Jackson ,  Dennis Lorah ,  Darren Marsh ,  David Rybarczyk ,  Frank Stubbs

    IPC分类号： C08L101/00 ,  C08K3/34 ,  C09C1/42 ,  C09C3/10 ,  C09D5/02 ,  C09D7/12 ,  C09D123/14 ,  C09D123/28 ,  C09D201/00 ,  C08L1/00

    CPC分类号： C09D5/028 ,  B82Y30/00 ,  C01P2002/88 ,  C01P2004/20 ,  C01P2004/64 ,  C01P2006/33 ,  C09C1/42 ,  C09C3/10

    摘要： The present invention provides aqueous dispersion compositions comprising one or more than one of each of aqueous dispersions of water-dispersible polymers and aqueous nanocomposite dispersions of at least partially exfoliated layered silicates and water-insoluble polymers to enhance the thermal shock resistance of a waterborne coating, film, or article comprising the composition. Only 2 to 10 phr of the layered silicate, e.g. sodium montmorillonite surprisingly enhances thermal shock resistance. Optional fillers, such as nepheline syenite, may be added. Such compositions may be coated on automotive plastic, TPO or resinous substrates, and provide coatings having a 19 or greater thermal shock resistance according to Ford laboratory test method BI 107-05 when coated on TPO and baked for 15 minutes at from 74 to 90° C. Further, the present invention provides methods of making aqueous nanocomposite dispersions comprising mixing unmodified layered silicate and water insoluble neat resin in water to at least partially exfoliate the clay and subjecting the resulting mixture to high shear.

    摘要翻译： 本发明提供水分散体组合物，其包含水分散性聚合物的水分散体和至少部分剥离的层状硅酸盐和水不溶性聚合物的水性纳米复合物分散体中的一种或多于一种，以增强水性涂料的耐热冲击性， 膜或包含该组合物的制品。 仅2〜10phr层状硅酸盐，例如 钠蒙脱石令人惊奇地提高耐热冲击性。 可以加入任选的填料，如霞石正长岩。 这种组合物可以涂覆在汽车塑料，TPO或树脂基材上，并且当涂覆在TPO上时，根据福特实验室测试方法BI 107-05提供具有19或更高耐热冲击性的涂层，并且在74至90度下烘烤15分钟 C.此外，本发明提供了制备水性纳米复合物分散体的方法，其包括将未改性的层状硅酸盐和水不溶性纯树脂混合在水中至少部分地剥离粘土并使所得混合物经受高剪切。