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公开(公告)号：US20190324020A1
公开(公告)日：2019-10-24
申请号：US16399050
申请日：2019-04-30
发明人： Hirokazu OHBAYASHI , Kayoko FUJITA
IPC分类号： G01N33/53 , G01N33/58 , G01N33/535 , G01N33/532 , G01N33/536 , C12Q1/68
摘要： The present invention relates to a combination product for detecting a target marker simply and with high sensitivity. More specifically, the present invention relates to a combination product for detecting a target marker in a biological sample in combination with a target marker binding molecule which is capable of binding specifically to the target marker in the biological sample, the combination comprising, at least: (a) a first binding agent comprising a first binding molecule which is capable of directly or indirectly binding specifically to the target marker binding molecule, and a labeling substance; (b) a linker molecule which is capable of binding specifically to the first binding agent; and (c) a second binding agent which is capable of binding specifically to the linker molecule, and comprises a second binding molecule and a labeling substance.
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公开(公告)号：US20190025164A1
公开(公告)日：2019-01-24
申请号：US16139569
申请日：2018-09-24
摘要： An automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges an occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples in the first region, suspends a start of a treatment for the samples in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples in the first region when the horizontal direction movement unit is not occupied.
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公开(公告)号：US20170292899A1
公开(公告)日：2017-10-12
申请号：US15511481
申请日：2015-09-18
CPC分类号： G01N1/312 , G01N1/28 , G01N1/30 , G01N33/48 , G01N35/00029 , G01N35/00722 , G01N35/0095 , G01N2035/00138 , G01N2035/00356
摘要： Provided are an automatic tissue staining device and an automatic tissue staining method capable of advancing treatments according to precise treatment times without a hitch. The automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples on the one or more glass slides situated in the first region, suspends a start of a treatment for the samples on the one or more glass slides situated in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples on the one or more glass slides situated in the first region when the horizontal direction movement unit is not occupied.
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公开(公告)号：US20160121282A1
公开(公告)日：2016-05-05
申请号：US14980278
申请日：2015-12-28
CPC分类号： B01F13/0818 , B01F13/08 , B01F15/00902 , B01F15/06 , B01F15/065 , B01F2015/062 , B01L7/02 , B01L2200/147 , G01N2035/00346
摘要： Provided is a thermostat with reduced temperature difference within the tank when a solution is being heat-treated. Stirring guides (114) for guiding a water-flow generated by a stirring bar (113) to both ends of a tank (106) in the longitudinal direction are disposed on the bottom of the tank (106). Thus, the water-flow generated by the stirring bar (113) is efficiently guided to both ends of the tank (106) in the longitudinal direction while keeping its momentum, and therefore a circulating water-flow for homogenizing the temperature of the water within the tank (106) can be effectively generated.
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公开(公告)号：US20160003718A1
公开(公告)日：2016-01-07
申请号：US14759612
申请日：2014-01-08
IPC分类号： G01N1/31
CPC分类号： G01N1/312 , B01L3/52 , B01L9/52 , B01L9/527 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/0621 , B01L2200/0684 , B01L2300/047 , B01L2300/048 , B01L2300/0822 , B01L2300/0877 , B01L2400/0406 , G01N1/30 , G01N35/1002
摘要： A liquid filling aid that is placed on a plate-shaped member and defines a reaction chamber to be filled with a liquid, the aid includes a main body, a storage section that is formed in the main body and stores the liquid, a reaction section that is a recess formed at a bottom of the main body, a communication aperture for fluid communication between the storage section and the reaction section, and an air vent for communication between the reaction section and outside air, wherein the reaction section and an upper surface of the plate-shaped member define the reaction chamber and a liquid filling method including a step of placing the liquid filling aid on the plate-shaped member, and a step of discharging the liquid in an amount equal to or larger than the volume of the reaction chamber for supply to the storage section.
摘要翻译： 一种液体填充辅助剂，其被放置在板状构件上并限定要填充液体的反应室，所述助剂包括主体，形成在主体中并存储液体的储存部分，反应部分 是形成在主体的底部的凹部，用于存储部和反应部之间的流体连通的连通孔，以及用于反应部和外部空气之间连通的排气口，其中反应部和上表面 所述板状构件限定所述反应室，以及液体填充方法，包括将所述液体填充辅助剂放置在所述板状构件上的步骤，以及以等于或大于所述板状构件的体积的量排出所述液体的步骤 反应室供给储存部分。
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公开(公告)号：US11733131B2
公开(公告)日：2023-08-22
申请号：US16609074
申请日：2018-04-27
发明人： Shinobu Masuda , Ryohei Suzuki , Yuriko Kitano
摘要： The present invention is to provide a tissue slice selection method and an embedded block-preparing cassette which are capable of suppressing occurrence of errors in inspection results. The present invention makes it possible to suppress the occurrence of errors in inspection results by including: an embedded block-preparing process of preparing an embedded block by embedding both a biological tissue fragment and a standard substance in the same embedding agent; an embedded tissue slice preparing step of slicing the embedded block to prepare a sheet-like embedded tissue slice having a tissue slice and standard substance slices appearing on a surface thereof; and a tissue slice selecting step of selecting the tissue slice to be inspected, based on a light signal from the standard substance slice.
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公开(公告)号：US10119892B2
公开(公告)日：2018-11-06
申请号：US15511481
申请日：2015-09-18
摘要： An automatic tissue staining device includes a supply head that supplies a treatment fluid, a horizontal direction movement unit that moves the supply head in a horizontal direction, and a holding unit that holds a plurality of glass slides on which samples are set. The automatic tissue staining device further includes a control unit that judges an occupancy status of the horizontal direction movement unit in a condition that one or more of the glass slides are situated in a first region prior to supplying the treatment fluid from the supply head to one or more samples in the first region, suspends a start of a treatment for the samples in the first region when the horizontal direction movement unit is occupied, and permits the treatment for the samples in the first region when the horizontal direction movement unit is not occupied.
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公开(公告)号：US09719896B2
公开(公告)日：2017-08-01
申请号：US14759612
申请日：2014-01-08
CPC分类号： G01N1/312 , B01L3/52 , B01L9/52 , B01L9/527 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/0621 , B01L2200/0684 , B01L2300/047 , B01L2300/048 , B01L2300/0822 , B01L2300/0877 , B01L2400/0406 , G01N1/30 , G01N35/1002
摘要： A liquid filling aid that is placed on a plate-shaped member and defines a reaction chamber to be filled with a liquid, the aid includes a main body, a storage section that is formed in the main body and stores the liquid, a reaction section that is a recess formed at a bottom of the main body, a communication aperture for fluid communication between the storage section and the reaction section, and an air vent for communication between the reaction section and outside air, wherein the reaction section and an upper surface of the plate-shaped member define the reaction chamber and a liquid filling method including a step of placing the liquid filling aid on the plate-shaped member, and a step of discharging the liquid in an amount equal to or larger than the volume of the reaction chamber for supply to the storage section.
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公开(公告)号：US20160038943A1
公开(公告)日：2016-02-11
申请号：US14776546
申请日：2014-04-04
IPC分类号： B01L3/00
CPC分类号： B01L3/523 , B01L3/5457 , B01L2200/16 , B01L2300/021 , B01L2300/025 , B01L2300/04 , B01L2300/043 , B01L2300/0809 , B01L2300/0832 , B01L2300/0851 , G01N35/00 , G01N35/02
摘要： This receptacle containing a test reagent is provided with: an information display part, situated on the upper surface, for display of information relating to a test reagent contained in the receptacle body; and a lid part connected to the upper surface and rotatable with respect to the receptacle body, for opening and closing a passage hole. The lid part closes off the passage hole such that the information display part is visible.
摘要翻译： 容纳测试试剂的容器设置有：信息显示部，位于上表面，用于显示与容纳体内所含的试剂有关的信息; 以及盖部，其连接到所述上表面并且相对于所述容器主体可旋转，用于打开和关闭通道孔。 盖部分封闭通道孔，使信息显示部分可见。
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