Abstract:
This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human inteferon like alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.
Abstract translation:本申请涉及重组人类干扰素样蛋白。 在一个实施方案中,描述了与天然存在的人类干扰素如α2b(HuIFN-α2b)相比,通过基因改组技术产生的重组蛋白具有增强的抗病毒和抗增殖活性。 本发明包括编码蛋白质的多核苷酸和包含多核苷酸的重组载体和宿主细胞。 优选地,多核苷酸选自各自具有与SEQ ID:No.1至少93%相同的序列的多核苷酸,并且所述蛋白质选自蛋白质组,其各自具有与SEQ ID NO:至少85%相同的氨基酸序列 否:2.包含蛋白质的蛋白质和组合物可用于治疗对干扰素治疗(例如病毒性疾病和癌症)有反应的病症。
Abstract:
A method includes defining a placeholder widget having a property and defining a prototype graphical user interface (GUI) having an instance of the placeholder widget. The method also includes presenting the prototype GUI to a user, where an appearance of the instance of the placeholder widget is based on the property of the placeholder widget. The method further includes replacing the instance of the placeholder widget in the prototype GUI with an instance of another widget. In addition, the method includes updating the presentation of the prototype GUI using the instance of the other widget. Replacing the instance of the placeholder widget with the instance of the other widget could include transforming an instance of a lower fidelity placeholder widget into an instance of a higher fidelity widget. The property of the placeholder widget could include a textual property, an image property, and/or a graphics property.
Abstract:
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
Abstract:
Disclosed is a silicon condenser microphone including a backplate having a plurality of perforations therethrough, a diaphragm opposed from the backplate for forming a capacitor. The diaphragm includes a first part and a second part received in the first part, the second part being capable of vibrating relative to the backplate. The first part is connected to the ground and the second part is connected to a bias voltage.
Abstract:
A system and method for automatically generating an adaptive user interface for a plurality of appliances within a physical environment. Appliance description specifications of the appliances are generated from provided appliance functionality information and semantic information of related appliances and/or related environment information. The appliance description specifications can be analyzed to construct a semantic functionality relationship among the appliances and the adaptive user interface can be rendered based on an interface elements relationship which is a transformation of the semantic functionality relationship. The system has a user interface rendering module, which when run on a controller, implements the aforesaid appliance description specification generation and analysis, and adaptor modules, which when run on the appliances, maintain the appliance description specifications and allow exchange of same between the controller and appliances.
Abstract:
An electromagnetic shielding composite includes a polymer and a carbon nanotube film structure. The carbon nanotube structure includes a number of carbon nanotubes disposed in the polymer. The number of carbon nanotubes are parallel with each other.
Abstract:
The present invention provides a method for revamping an HF or sulphuric acid alkylation unit to an ionic liquid alkylation unit, wherein the HF or sulphuric acid alkylation unit comprise at least: -a reactor unit for contacting catalyst and hydrocarbon reactants; -a separator unit for separating a reactor effluent into a catalyst phase and an alkylate-comprising hydrocarbon phase; -a fractionator unit for fractionating the alkylate-comprising hydrocarbon phase into at least one stream comprising alkylate; -a catalyst phase recycle means to recycle at least part of the catalyst phase from the separator unit to the reactor unit; which method includes: -adapting the catalyst phase recycle means by providing a means for acid injection and/or a means for halohydrocarbon injection into the catalyst recycle means. The invention further provides a method for the production of alkylate.
Abstract:
The present invention provides a method for revamping an HF or sulphuric acid alkylation unit to an ionic liquid alkylation unit, wherein the HF or sulphuric acid alkylation unit comprise at least: a reactor unit for contacting catalyst and hydrocarbon reactants; a separator unit for separating a reactor effluent into a catalyst phase and an alkylate-comprising hydrocarbon phase; a fractionator unit for fractionating the alkylate-comprising hydrocarbon phase into at least one stream comprising alkylate; and which method includes: providing one or more cyclone units downstream of the reactor unit to separate at least part of the reactor effluent in a catalyst phase and a alkylate-comprising hydrocarbon phase.
Abstract:
A method for simulating magnetic resonance signals is proposed. A lattice array where each point in the array has several magnetic resonance sensitive particles is provided. Statistic property of each point is set. A raw magnetic resonance imaging data is calculated based on statistic property of each point and a magnetic resonance imaging sequence to be applied. A system for simulating magnetic resonance signals is further proposed. By considering statistic property of each point, it can distinguish every part of the object to be scanned and really reflect the structure of object without using a real magnetic resonance imaging device. It saves time and costs for avoiding several scanning by the real a magnetic resonance imaging device.
Abstract:
An tri-axis accelerometer is disclosed. The tri-axis accelerometer includes a mass, a first group of capacitance, a third group of capacitance being neighbor to the first group of capacitance. The mass defines an upper surface, a lower surface parallel to the upper surface and a side wall connecting the upper surface and the lower surface. The first group of capacitance includes a first movable electrode and the third group of capacitance includes a third movable electrode. The first movable electrode is perpendicular to the third movable electrode.