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    Compositions for treating keratinous materials containing a combination of a zwitterion polymer and a water insoluble non-volatile silicon
    13.
    发明授权
    Compositions for treating keratinous materials containing a combination of a zwitterion polymer and a water insoluble non-volatile silicon 失效
    用于处理含有两性离子聚合物和水不溶性非挥发性硅的组合的角质材料的组合物

    公开(公告)号：US06555100B1

    公开(公告)日：2003-04-29

    申请号：US09380087

    申请日：1999-10-19

    Applicant: Serge Restle ,  Danièle Cauwet-Martin

    Inventor： Serge Restle ,  Danièle Cauwet-Martin

    IPC: A61K706

    CPC classification number: A61K8/891 ,  A61K8/8158 ,  A61K8/894 ,  A61Q5/02

    Abstract: The invention relates to a composition for treating keratin substances, in particular the hair, containing, in a cosmetically and/or dermatologically acceptable aqueous medium, at least: a) one zwitterionic polymer resulting from the copolymerization of at least one monomer of formula (I):  in which R1 and R2, which may be identical or different, represent a hydrogen atom or a methyl radical, and R3, R4 and R5, which may be identical or different, represent a linear or branched alkyl radical containing from 1 to 4 carbon atoms, Z represents an NH group or an oxygen atom, n is an integer from 2 to 5, A− is an anion derived from an organic or inorganic acid, and at least one monomer of formula (II): R6—CH═CR7—COOH  (II)  in which R6 and R7, which may be identical or different, represent a hydrogen atom or a methyl radical; the said polymer being soluble in water to a concentration of 1% by weight at a pH below 6 and at 20° C.; b) one non-amino, non-volatile, water-insoluble silicone with a viscosity of greater than 3×10−5 m2/s (300 centistokes).

    Abstract translation: 本发明涉及一种用于处理在美容和/或皮肤病学上可接受的水性介质中的角蛋白物质，特别是毛发的组合物，至少包含：a）由至少一种式（I）的单体共聚得到的一种两性离子聚合物 ）：其中可以相同或不同的R 1和R 2表示氢原子或甲基，R 3，R 4和R 5可以相同或不同，表示含有1至4个的直链或支链烷基 碳原子，Z表示NH基或氧原子，n为2〜5的整数，A-为有机酸或无机酸的阴离子，和至少一种式（II）的单体：其中R6和 R 7可以相同或不同，表示氢原子或甲基;所述聚合物在pH低于6和20℃下可溶于水至1重量％的浓度; b） 氨基，非挥发性，水不溶性硅酮，粘度大于 3×10-5平方米/秒（300厘沲）。

    Detergent cosmetic composition comprising a silicone and an amphoteric polymer with fatty chains and use
    15.
    发明授权
    Detergent cosmetic composition comprising a silicone and an amphoteric polymer with fatty chains and use 失效
    洗涤剂化妆品组合物，其包含硅氧烷和具有脂肪链的两性聚合物和用途

    公开(公告)号：US06511671B1

    公开(公告)日：2003-01-28

    申请号：US09599831

    申请日：2000-06-23

    Applicant: Claude Dubief ,  Serge Restle ,  Géraldine Fack

    Inventor： Claude Dubief ,  Serge Restle ,  Géraldine Fack

    IPC: A61K706

    CPC classification number: A61Q19/10 ,  A61K8/8158 ,  A61K8/891 ,  A61K2800/5428 ,  A61Q5/02 ,  Y10S514/881

    Abstract: Detergent composition comprising, in a cosmetically acceptable medium, at least one washing base, at least one water-insoluble silicone and at least one amphoteric polymer comprising from 1 to 20 mol % of at least one monomeric unit chosen from (meth)acrylate and (meth)acrylamide types having at least one fatty chain, the fatty chain having from 8 to 30 carbon atoms. These compositions may possess improved cosmetic properties, in particular the sleeking of the hair. The compositions can be used for cleaning, care and styling of the hair.

    Abstract translation: 洗涤剂组合物，其在化妆品可接受的介质中包含至少一种洗涤碱，至少一种水不溶性硅氧烷和至少一种两性聚合物，其包含1至20摩尔％的至少一种选自（甲基）丙烯酸酯和（甲基）丙烯酸酯的单体单元， 具有至少一个脂肪链的甲基丙烯酰胺类型，所述脂肪链具有8至30个碳原子。 这些组合物可具有改善的化妆品性质，特别是头发的时尚。 组合物可用于清洁，护理和造型头发。

    Process for the preparation of 6-piperidino-2,4-diamino pyrimidine-3-oxide
    17.
    发明授权
    Process for the preparation of 6-piperidino-2,4-diamino pyrimidine-3-oxide 失效
    6-哌啶基-2,4-二氨基嘧啶-3-氧化物的制备方法

    公开(公告)号：US4985563A

    公开(公告)日：1991-01-15

    申请号：US225819

    申请日：1988-07-29

    Applicant: Jean Maignan ,  Serge Restle ,  Gerard Lang

    Inventor： Jean Maignan ,  Serge Restle ,  Gerard Lang

    IPC: A61K8/00 ,  A61K8/49 ,  A61Q5/00 ,  C07D239/48 ,  C07D239/50 ,  C07D239/52

    CPC classification number: C07D239/48 ,  C07D239/50 ,  Y02P20/55

    Abstract: In a first stage of a process for the preparation of 6-piperidino-2,4-diaminopyrimidine-3-oxide at least one of the two amino groups of a compound having formula (1): ##STR1## where x represents a halogen atom or OH group, is protected by an addition reaction with an isocyanate having formula:R--N=C=OIn this formula R represents an alkyl group, or one of the amino groups. The resulting urea derivative is then oxidized to produce the corresponding N-oxide which is then reacted with piperidine. The protective group(s) are then eliminated by reaction with an organic or inorganic base.

    Abstract translation: 在制备具有式（1）的化合物的两个氨基中的至少一个的6-哌啶基-2,4-二氨基嘧啶-3-氧化物的方法的第一阶段：其中x表示 通过与具有下式的异氰酸酯的加成反应来保护卤素原子或OH基团：RN = C = O在该式中，R表示烷基或氨基之一。 然后将所得的脲衍生物氧化以产生相应的N-氧化物，然后与哌啶反应。 然后通过与有机或无机碱反应除去保护基。

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