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公开(公告)号：US08900619B2
公开(公告)日：2014-12-02
申请号：US11827462
申请日：2007-07-11
申请人： Shrirang V. Ranade , Courtney Sikes , Mark Steckel
发明人： Shrirang V. Ranade , Courtney Sikes , Mark Steckel
IPC分类号： A61F2/00 , A61L27/54 , A61L31/16 , A61L29/14 , A61L27/58 , A61L29/08 , A61L31/14 , A61L27/34 , A61L31/10 , A61L29/16
CPC分类号： A61L27/58 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/604
摘要： According to one aspect of the invention, medical devices are provided which contain the following: (a) an interior region that contains at least one degradation promoting agent and (b) an exterior region disposed over the interior region that contains at least one biodegradable polymer and at least one therapeutic agent.
摘要翻译： 根据本发明的一个方面，提供了包含以下物质的医疗装置：（a）含有至少一种降解促进剂的内部区域和（b）设置在内部区域上的外部区域，其包含至少一种可生物降解的聚合物 和至少一种治疗剂。
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12.发明授权Drug release regions for medical devices, which include polycyclic-structure-containing polymers 有权用于医疗器械的药物释放区域，其包括含多环结构的聚合物公开(公告)号：US08067026B2
公开(公告)日：2011-11-29
申请号：US11079621
申请日：2005-03-14
摘要： According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain polymeric release regions that control the release of one or more therapeutic agents. The polymeric release regions, in turn, contain one or more polymers that contain one or more rigid, nonplanar polycyclic molecular structures. The therapeutic agent is disposed beneath or within the polymeric release region.
摘要翻译： 根据本发明的一个方面，提供了可植入或可插入的医疗装置，其包含控制一种或多种治疗剂的释放的聚合物释放区域。 聚合物释放区域又包含一种或多种含有一个或多个刚性非平面多环分子结构的聚合物。 治疗剂设置在聚合物释放区域的下方或内部。
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13.发明授权Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces 有权用于向疏水性医疗用品表面赋予生物活性的生物活性聚合物公开(公告)号：US07625552B2
公开(公告)日：2009-12-01
申请号：US11442773
申请日：2006-05-30
IPC分类号： A61K38/05 , A61K38/06 , A61K38/08 , A61K38/16 , A61K31/727 , A61K31/785 , C08G63/91
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/236 , A61L2300/25
摘要： According to an aspect of the present invention, bioactive polymers are provided which have (a) a hydrophilic bioactive portion and (b) at least one hydrophobic polymer group that is linked to the hydrophilic bioactive portion by a covalent linkage that contains a chain transfer agent residue. According to another aspect of the present invention, medical articles are provided with bioactive surface by coating them with a coating material that contains such bioactive polymers.
摘要翻译： 根据本发明的一个方面，提供了生物活性聚合物，其具有（a）亲水性生物活性部分和（b）通过含有链转移剂的共价键与亲水生物活性部分连接的至少一个疏水性聚合物基团 残留物 根据本发明的另一方面，通过用包含这种生物活性聚合物的涂层材料涂覆医疗制品来提供生物活性表面。
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公开(公告)号：US20090098176A1
公开(公告)日：2009-04-16
申请号：US12207839
申请日：2008-09-10
IPC分类号： A61K47/30 , C08G73/02 , C08F226/08 , C08B1/00 , C08B37/04 , C08B37/08 , C08L71/02 , A61K47/36 , A61K47/42 , A61F2/02 , A61K9/70 , A61K9/00 , A61K31/337 , A61K31/436 , A61K47/38 , C07K14/78 , C08F210/00 , C08G63/06 , C08G67/00 , C08G73/00 , C08G73/10
CPC分类号： A61L31/145 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/416
摘要： Described herein are implantable medical devices comprising a biocompatible polymer comprising a triggerable bioadhesive property that allows the device to adhere to body tissue. The triggerable bioadhesive property of the polymer can be triggered or activated by exposure to a stimulus. Also, the present invention pertains to methods of making an implantable medical device comprising a biocompatible polymer comprising a triggerable bioadhesive property that allows the device to adhere to body tissue.
摘要翻译： 本文描述的是可植入医疗装置，其包括生物相容性聚合物，其包含可触发的生物粘合性质，其允许该装置粘附于身体组织。 可以通过暴露于刺激物来触发或激活聚合物的可触发生物粘附性质。 此外，本发明涉及制造包括生物相容性聚合物的可植入医疗装置的方法，所述生物相容性聚合物包含允许装置粘附于身体组织的可触发的生物粘合性质。
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公开(公告)号：US20080050418A1
公开(公告)日：2008-02-28
申请号：US11827462
申请日：2007-07-11
申请人： Shrirang V. Ranade , Courtney Sikes , Mark Steckel
发明人： Shrirang V. Ranade , Courtney Sikes , Mark Steckel
IPC分类号： A61F2/04
CPC分类号： A61L27/58 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/604
摘要： According to one aspect of the invention, medical devices are provided which contain the following: (a) an interior region that contains at least one degradation promoting agent and (b) an exterior region disposed over the interior region that contains at least one biodegradable polymer and at least one therapeutic agent.
摘要翻译： 根据本发明的一个方面，提供了包含以下物质的医疗装置：（a）含有至少一种降解促进剂的内部区域和（b）设置在内部区域上的外部区域，其包含至少一种可生物降解的聚合物 和至少一种治疗剂。
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公开(公告)号：US09095364B2
公开(公告)日：2015-08-04
申请号：US13551849
申请日：2012-07-18
申请人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
发明人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
CPC分类号： A61B17/24 , A61B6/12 , A61M16/0057 , A61M16/04 , A61M16/0438 , A61M16/044 , A61M16/0445 , A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0816 , A61M25/0026 , A61M25/007 , A61M29/02 , A61M2205/32 , A61M2205/6081
摘要： A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway.
摘要翻译： 描述了医疗装置和系统，并且用于扩张患者的狭窄气道。 医疗装置包括近端，远端以及具有充气腔和远端的通气腔的轴系。 轴系具有近轴部分和远侧轴部分。 可膨胀的气球在远端轴部分附近位于远端的位置。 通气尖端在远侧轴部分上的球囊的远侧，并且具有一个或多个径向面对的开口。 用于治疗狭窄性气道的方法包括将医疗装置插入患者的气道中，并使气道扩张和通气。
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公开(公告)号：US20130184568A1
公开(公告)日：2013-07-18
申请号：US13551849
申请日：2012-07-18
申请人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
发明人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
CPC分类号： A61B17/24 , A61B6/12 , A61M16/0057 , A61M16/04 , A61M16/0438 , A61M16/044 , A61M16/0445 , A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0816 , A61M25/0026 , A61M25/007 , A61M29/02 , A61M2205/32 , A61M2205/6081
摘要： A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway.
摘要翻译： 描述了医疗装置和系统，并且用于扩张患者的狭窄气道。 医疗装置包括近端，远端以及具有充气腔和远端的通气腔的轴系。 轴系具有近轴部分和远侧轴部分。 可膨胀的气球在远端轴部分附近位于远端的位置。 通气尖端在远侧轴部分上的球囊的远侧，并且具有一个或多个径向面对的开口。 用于治疗狭窄性气道的方法包括将医疗装置插入患者的气道中，并使气道扩张和通气。
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公开(公告)号：US07914806B2
公开(公告)日：2011-03-29
申请号：US11444804
申请日：2006-06-01
CPC分类号： A61L29/041 , A61L27/16 , A61L29/16 , A61L31/048 , A61L31/16 , A61L2300/00 , C08L53/005
摘要： According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at least one therapeutic agent.
摘要翻译： 根据本发明的一个方面，提供了包含至少一个聚合物区域的医疗装置，所述至少一个聚合物区域包含（a）至少一种包含至少三个彼此不同的聚合物嵌段的嵌段共聚物，和（b）至少一种治疗 代理商
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