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45 条记录 (耗时 0.03 秒)

    Method for producing polyunsaturated fatty acids
    11.
    发明授权
    Method for producing polyunsaturated fatty acids 有权

    公开(公告)号：US10190131B2

    公开(公告)日：2019-01-29

    申请号：US12280090

    申请日：2007-02-21

    申请人： Petra Cirpus ,  Jörg Bauer ,  Xiao Qiu ,  Guohai Wu ,  Bifang Cheng ,  Martin Truksa ,  Tom Wetjen

    发明人： Petra Cirpus ,  Jörg Bauer ,  Xiao Qiu ,  Guohai Wu ,  Bifang Cheng ,  Martin Truksa ,  Tom Wetjen

    IPC分类号： A61K31/20 ,  C12N15/82 ,  C12N9/02 ,  C12N9/10 ,  C12N15/52 ,  C12P7/64

    摘要： The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.

    Fatty acid elongase and uses thereof
    12.
    发明授权
    Fatty acid elongase and uses thereof 有权
    脂肪酸延长酶及其用途

    公开(公告)号：US09347049B2

    公开(公告)日：2016-05-24

    申请号：US13511386

    申请日：2010-11-23

    申请人： Jörg Bauer ,  Xiao Qiu ,  Patricia Vrinten

    发明人： Jörg Bauer ,  Xiao Qiu ,  Patricia Vrinten

    IPC分类号： C12N15/82 ,  C12N9/10 ,  C12N9/02 ,  C12P7/64

    CPC分类号： C12N9/1029 ,  C12N9/0083 ,  C12N15/8247 ,  C12P7/6427 ,  Y02P20/52

    摘要： The present invention relates to nucleic acids derived from Sphaeroforma arctica. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to linoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.

    摘要翻译： 本发明涉及来源于Sphaeroforma arctica的核酸。 本发明还涉及个体编码序列和由这些序列与其它序列组合编码的蛋白质以及将油酸转化为亚油酸至亚油酸的方法，以及花生四烯酸，二十碳五烯酸和/或二十二碳六烯酸 酸在植物中。

    Novel Omega-3 Fatty Acid Desaturase Family Members and Uses Thereof
    15.
    发明申请
    Novel Omega-3 Fatty Acid Desaturase Family Members and Uses Thereof 失效
    新型Omega-3脂肪酸去饱和酶家族成员及其用途

    公开(公告)号：US20090055973A1

    公开(公告)日：2009-02-26

    申请号：US11883134

    申请日：2006-02-07

    申请人： Patricia Vrinten ,  Xiao Qiu

    发明人： Patricia Vrinten ,  Xiao Qiu

    IPC分类号： C12N15/11 ,  C12N15/82 ,  C12N5/10 ,  C07K14/00 ,  A01H5/00 ,  C12Q1/68

    CPC分类号： C12N15/8234 ,  C12N9/0083 ,  C12N15/8247

    摘要： The present invention relates to the isolation of a second omega-3 fatty acid desaturase (FAD3) gene in flax (Linum usitatissimum) and its promoter region, as well as the identification of FAD3 mutant alleles, and the development of markers for wild type and mutated alleles. The FAD3 genes encode the enzymes which control omega-3 fatty acid desaturation and, thus, the levels of linolenic acid (18:3(n-3)). Accordingly, the molecules of the present invention can be utilized, for example, to develop markers for the mutations in flax FAD3 genes and for seed-specific modification of fatty acid and protein compositions in plant seeds.

    摘要翻译： 本发明涉及在亚麻（Linum usitatissimum）及其启动子区域中分离第二个ω-3脂肪酸去饱和酶（FAD3）基因，以及FAD3突变体等位基因的鉴定，以及野生型和 突变等位基因 FAD3基因编码控制ω-3脂肪酸去饱和的酶，从而编码亚麻酸（18：3（n-3））的水平。 因此，本发明的分子可以用于例如开发亚麻FAD3基因突变的标记物，以及植物种子中脂肪酸和蛋白质组合物的种子特异性修饰。

    Flax (Linum usitatissimum L.) seed-specific promoters
    16.
    发明授权
    Flax (Linum usitatissimum L.) seed-specific promoters 有权
    亚麻（Linum usitatissimum L.）种子特异性启动子

    公开(公告)号：US07473820B2

    公开(公告)日：2009-01-06

    申请号：US11655545

    申请日：2007-01-19

    申请人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

    发明人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

    IPC分类号： C12P7/62 ,  C12P11/00 ,  C07H21/04 ,  A01H1/00

    CPC分类号： C12N15/8234 ,  C07K14/415 ,  C12N15/8247

    摘要： The present invention is directed to promoters of flax conlinin and ω-3 desaturase genes. The promoters guide high levels of the expression exclusively in flax developing seeds. This specific expression pattern concomitant with the biosynthesis of storage lipids and proteins make these promoters particularly useful for seed-specific modification of fatty acid and protein compositions in plant seeds.

    摘要翻译： 本发明涉及亚麻精蛋白和ω-3去饱和酶基因的启动子。 启动子引导高水平的表达专门在亚麻发育种子。 这种特异性表达模式伴随着储存脂质和蛋白质的生物合成，使得这些启动子特别适用于植物种子中脂肪酸和蛋白质组成的种子特异性修饰。

    Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
    19.
    发明授权
    Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains 有权
    对所有长于18个碳链的所有ω-6脂肪酸具有特异性的新型ium ium ium ome 3去饱和酶的分离和表征

    公开(公告)号：US09029111B2

    公开(公告)日：2015-05-12

    申请号：US12438373

    申请日：2007-08-16

    申请人： Jörg Bauer ,  Guohai Wu ,  Xiao Qiu

    发明人： Jörg Bauer ,  Guohai Wu ,  Xiao Qiu

    IPC分类号： C12P7/64 ,  C12N9/02 ,  C12N15/52 ,  C12N9/04

    CPC分类号： C12P7/6472 ,  A61K8/64 ,  A61K8/922 ,  A61K31/202 ,  A61K2800/10 ,  A61Q19/00 ,  C12N9/0006 ,  C12N9/0083 ,  C12N9/0093 ,  C12N15/52 ,  C12P7/6427 ,  C12P7/6436

    摘要： The present invention relates to a polynucleotide encoding an omega 3 (ω-3) desaturase from Pythium irregulare with specificity to long chain polyunsaturated omega 6 (ω-6) fatty acids as well as a vector containing said polynucleotide, and a host cell containing the vector or the polynucleotide. Moreover, the present invention pertains to a polypeptide encoded by the said polynucleotide, antibodies against the polypeptide as well as a method for the manufacture of the polypeptide. Further, encompassed by the present invention are transgenic non-human organisms. Finally, the present invention relates to methods for the manufacture of compounds and oil- fatty acid- or lipid-containing compositions.

    摘要翻译： 本发明涉及编码具有对长链多不饱和ω-6（ω-6）脂肪酸的特异性的不锈菌的ω-3（ω-3）去饱和酶的多核苷酸以及含有所述多核苷酸的载体和含有 载体或多核苷酸。 此外，本发明涉及由所述多核苷酸编码的多肽，针对多肽的抗体以及制备多肽的方法。 此外，本发明包括转基因非人生物体。 最后，本发明涉及制备化合物和含油脂肪酸或含脂质的组合物的方法。