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公开(公告)号：US20190276817A1
公开(公告)日：2019-09-12
申请号：US16170980
申请日：2018-10-25
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/6874 , G01N33/543 , C12N15/11 , C12Q1/6876 , C12Q1/6806
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20180371540A1
公开(公告)日：2018-12-27
申请号：US16052486
申请日：2018-08-01
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/6869 , C12Q1/6855
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号：US20180051321A1
公开(公告)日：2018-02-22
申请号：US15718893
申请日：2017-09-28
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
CPC classification number: C12Q1/6806 , B01J2219/005 , B01J2219/00547 , B01J2219/00572 , B01J2219/00722 , C12N15/1006 , C12N15/1065 , C12Q2535/122 , C12Q2563/159
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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14.发明申请公开(公告)号：US20180015472A1
公开(公告)日：2018-01-18
申请号：US15717840
申请日：2017-09-27
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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15.发明申请公开(公告)号：US20170348691A1
公开(公告)日：2017-12-07
申请号：US15596754
申请日：2017-05-16
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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Patent Agency Ranking
公开(公告)号：US20170342404A1
公开(公告)日：2017-11-30
申请号：US15470814
申请日：2017-03-27
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/68 , C12N15/11 , G01N33/543
CPC classification number: C12N15/1065 , C12N15/11 , C12Q1/6806 , C12Q1/6874 , C12Q1/6876 , C12Q2600/112 , G01N33/5436
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20220154175A1
公开(公告)日：2022-05-19
申请号：US17517287
申请日：2021-11-02
Applicant: 10x Genomics, Inc.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/6806 , C12N15/11 , G01N33/543 , C12Q1/6876 , C12Q1/6874
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US11193121B2
公开(公告)日：2021-12-07
申请号：US16170980
申请日：2018-10-25
Applicant: 10X GENOMICS, INC.
Inventor： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC: C12N15/10 , C12Q1/6806 , C12N15/11 , G01N33/543 , C12Q1/6876 , C12Q1/6874
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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19.发明授权公开(公告)号：US10343166B2
公开(公告)日：2019-07-09
申请号：US15596754
申请日：2017-05-16
Applicant: 10X Genomics, Inc.
Inventor： Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号：US20180363029A1
公开(公告)日：2018-12-20
申请号：US16056231
申请日：2018-08-06
Applicant: 10X Genomics, Inc.
Inventor： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serger Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6806 , C12N15/10
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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