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    Mechanical zoom imaging apparatus
    11.
    发明授权
    Mechanical zoom imaging apparatus 有权

    公开(公告)号：US09618733B2

    公开(公告)日：2017-04-11

    申请号：US14444709

    申请日：2014-07-28

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Steve Swihart ,  Evan Thrush ,  Evelio Perez ,  Kevin McDonald

    IPC: G02B15/14

    CPC classification number: G02B15/14

    Abstract: An imaging assembly for the viewing, imaging, and analysis of chemiluminescent or bioluminescent samples in gels or other substrates, in which an adjustable camera and lens module having a prime or fixed lens or a focusing lens is moved to change the field of view by shifting the focal plane of the camera and lens module. The imaging assembly can also include a mirror to bend or fold the optical path between the camera and lens module and the target area having a sample, in which the mirror can move in the same vertical direction as the camera and lens module. Further, the camera and lens module can be configured to more move in a diagonal direction relative to the location of the imaging target area. The imaging assembly can further have a duct system adaptable to adjust with the movement of the camera and lens module.

    CONTACT IMAGER
    12.
    发明申请
    CONTACT IMAGER 有权
    联系IMAGER

    公开(公告)号：US20160006910A1

    公开(公告)日：2016-01-07

    申请号：US14789717

    申请日：2015-07-01

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Yochanan Uri ,  Boaz Ran ,  Itay Barak ,  Steven Swihart ,  Evan Thrush

    IPC: H04N5/225

    CPC classification number: H04N5/2252 ,  G01N21/76 ,  G01N21/763 ,  G01N2201/0221

    Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.

    Abstract translation: 本文提供了用于检测发光和/或放射性信号的成像盒。 这样的盒可用于常见的生物测定，例如免疫测定，核苷酸检测测定和其他亲和测定。

    Method and composition for quantifying protein using tagged standards
    13.
    发明授权
    Method and composition for quantifying protein using tagged standards 有权

    公开(公告)号：US12259356B2

    公开(公告)日：2025-03-25

    申请号：US17544591

    申请日：2021-12-07

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Kenneth Oh ,  Carl Marlowe ,  Stephen L. Swihart ,  Evan Thrush ,  Michael Griffin

    IPC: G01N27/447 ,  G01N21/64 ,  G01N33/58 ,  G01N33/68

    Abstract: Methods and reference compositions for quantifying protein using tagged standards. In an exemplary method, a reference composition and a protein may be electrophoresed in respective lanes of a gel. The reference composition may include quantitation standards of different size and each including a tag present at a different concentration. The quantitation standards and the protein may be transferred from the gel to a solid support to create a blot. Luminescence may be detected from the blot to obtain respective luminescence values separately representing an abundance of the tag of each quantitation standard and an abundance of the protein. A quantity of the protein may be determined using the respective luminescence values.

    Electronic component assembly with thermally conductive structures for image sensors
    15.
    发明授权
    Electronic component assembly with thermally conductive structures for image sensors 有权

    公开(公告)号：US11553116B2

    公开(公告)日：2023-01-10

    申请号：US17108672

    申请日：2020-12-01

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： Stephen Swihart ,  Li Lu ,  Wade Jameson ,  Evan Thrush ,  Michael Griffin ,  Evelio Perez

    IPC: H04N5/225 ,  H05K7/20

    Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.

    DIGITAL IMAGING WITH MASKED PIXELS
    17.
    发明申请
    DIGITAL IMAGING WITH MASKED PIXELS 有权
    数字成像与屏蔽像素

    公开(公告)号：US20160028976A1

    公开(公告)日：2016-01-28

    申请号：US14563411

    申请日：2014-12-08

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Boaz Ran ,  Steve Swihart ,  Evan Thrush ,  Itay Barak

    IPC: H04N5/361 ,  H04N5/365

    CPC classification number: H04N5/361 ,  H04N5/365

    Abstract: One embodiment of the invention is directed to an imaging device comprising an image sensor comprising an array of pixels, and a mask coupled with the image sensor, the mask configured to darken at least one pixel in the array of pixels.

    Abstract translation: 本发明的一个实施例涉及一种包括包括像素阵列的图像传感器和与图像传感器耦合的掩模的成像装置，该掩模被配置为使像素阵列中的至少一个像素变暗。

    Mechanical Zoom Imaging Apparatus
    18.
    发明申请
    Mechanical Zoom Imaging Apparatus 有权
    机械变焦成像设备

    公开(公告)号：US20150029595A1

    公开(公告)日：2015-01-29

    申请号：US14444709

    申请日：2014-07-28

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Steve Swihart ,  Evan Thrush ,  Evelio Perez ,  Kevin McDonald

    IPC: G02B15/14

    CPC classification number: G02B15/14

    Abstract: An imaging assembly for the viewing, imaging, and analysis of chemiluminescent or bioluminescent samples in gels or other substrates, in which an adjustable camera and lens module having a prime or fixed lens or a focusing lens is moved to change the field of view by shifting the focal plane of the camera and lens module. The imaging assembly can also include a mirror to bend or fold the optical path between the camera and lens module and the target area having a sample, in which the mirror can move in the same vertical direction as the camera and lens module. Further, the camera and lens module can be configured to more move in a diagonal direction relative to the location of the imaging target area. The imaging assembly can further have a duct system adaptable to adjust with the movement of the camera and lens module.

    Abstract translation: 用于在凝胶或其它基底中观察，成像和分析化学发光或生物发光样品的成像组件，其中具有主要或固定透镜或聚焦透镜的可调节照相机和透镜模块移动以通过移动来改变视场 相机和镜头模块的焦平面。 成像组件还可以包括用于弯曲或折叠相机和透镜模块之间的光路的反射镜和具有样品的目标区域，其中反射镜可以在与相机和透镜模块相同的垂直方向上移动。 此外，相机和透镜模块可以被配置为相对于成像目标区域的位置在对角线方向上更多地移动。 成像组件还可以具有适于根据相机和透镜模块的运动进行调节的管道系统。

    IMAGE CAPTURE FOR LARGE ANALYTE ARRAYS
    19.
    发明申请
    IMAGE CAPTURE FOR LARGE ANALYTE ARRAYS 审中-公开
    大数据分析系统的图像捕获

    公开(公告)号：US20140106989A1

    公开(公告)日：2014-04-17

    申请号：US14056162

    申请日：2013-10-17

    Applicant: Bio-Rad Laboratories, Inc., LSG - LSD Division

    Inventor： John Barich ,  Renee Lemaire-Adkins ,  David Neaz ,  Ariel Notcovich ,  Paul Patt ,  Ryan Short ,  Steven Swihart ,  Evan Thrush

    IPC: G01N21/63

    Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.

    Abstract translation: 分析物阵列如电泳后的板状凝胶中的溶质，特别是超过3cm见方和高达25cm见方的高达25cm见方的阵列，通过以下方式成像5cm或更小的距离： 整个阵列并通过基于计算机的缝合技术将子图像拼接在一起，或者通过使用与分析物阵列共同延伸以形成阵列的单个图像的薄膜光响应元件阵列来拼接子图像。

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