公开(公告)号：US10674964B2

公开(公告)日：2020-06-09

申请号：US15962468

申请日：2018-04-25

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Dean Montgomery

IPC: A61B5/00 ,  A61B5/0205 ,  G16H20/30 ,  A61B5/1455 ,  A61B5/021 ,  A61B5/0295

Abstract: In some examples, a device includes processing circuitry configured to determine a set of correlation coefficient values for first and second physiological parameters. The processing circuitry is further configured to determine a metric of the correlation coefficient values for a first plurality of bins and for a second plurality of bins, wherein each bin of the first plurality has a first bin parameter and each bin of the second plurality of bins has a second bin parameter different than the first bin parameter. The processing circuitry is also configured to determine a composite estimate of a limit of autoregulation of the patient based on the metric for the first plurality of bins and the metric for the second plurality of bins. The processing circuitry is configured to determine an autoregulation status based on the composite estimate and output, for display via the display, an indication of the autoregulation status.

公开(公告)号：US20180014791A1

公开(公告)日：2018-01-18

申请号：US15648665

申请日：2017-07-13

Applicant: COVIDIEN LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Peter Galen

IPC: A61B5/00 ,  A61B5/1455 ,  A61B5/021

CPC classification number: A61B5/7275 ,  A61B5/021 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/7246 ,  G16H50/30

Abstract: A system for monitoring autoregulation includes an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient. The system also includes a controller having a processor configured to receive a blood pressure signal indicative of a blood pressure of the patient and the oxygen saturation signal, determine a change in the oxygen saturation signal and a change in the blood pressure signal over a period of time, and provide an indication that the patient's autoregulation is intact if the oxygen saturation changes by more than an oxygen saturation threshold and if the blood pressure changes by less than a blood pressure threshold during the period of time.

公开(公告)号：US20170105672A1

公开(公告)日：2017-04-20

申请号：US15293610

申请日：2016-10-14

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  James N. Watson ,  Dean Montgomery

IPC: A61B5/00 ,  A61B5/1455 ,  A61B5/02 ,  A61B5/026

CPC classification number: A61B5/4076 ,  A61B5/02028 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/0261 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/6801 ,  A61B5/7264 ,  A61B5/7275 ,  G16H20/40 ,  G16H40/63 ,  G16H50/20 ,  G16H50/30

Abstract: A system configured to monitor autoregulation includes a medical sensor configured to be applied to a patient and to generate a regional oxygen saturation signal. The system includes a controller having a processor configured to receive the regional oxygen saturation signal and a blood pressure signal and to determine a cerebral oximetry index (COx) based on the blood pressure signal and the regional oxygen saturation signal. The processor is also configured to apply a data clustering algorithm to cluster COx data points over a range of blood pressures, identify a first cluster of COx data points that corresponds to an intact autoregulation zone for the patient, and provide a first output indicative of the intact autoregulation zone for the patient.

公开(公告)号：US20170095161A1

公开(公告)日：2017-04-06

申请号：US15285634

申请日：2016-10-05

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  James N. Watson ,  Dean Montgomery

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/0205 ,  A61B5/02108 ,  A61B5/02125 ,  A61B5/022 ,  A61B5/14553 ,  A61B5/6814 ,  A61B5/6826 ,  A61B5/7246 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746

Abstract: A method for monitoring autoregulation includes, using a processor, receiving a blood pressure signal an oxygen saturation signal, and a regional oxygen saturation signal from a patient. The method also includes normalizing the regional oxygen saturation signal to correct for variation in the oxygen saturation signal based on a relationship between the oxygen saturation signal and the regional oxygen saturation signal. The method further includes determining a linear correlation between the blood pressure signal and the normalized regional oxygen saturation signal. The method still further includes providing a signal indicative of the patient's autoregulation status to an output device based on the linear correlation.

公开(公告)号：US12268478B2

公开(公告)日：2025-04-08

申请号：US17188708

申请日：2021-03-01

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Dean Montgomery ,  Andre Antunes

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/021 ,  A61B5/1455 ,  A61B5/20 ,  G16H10/60

Abstract: A system for monitoring autoregulation may include processing circuitry configured to receive a blood pressure signal indicative of an acquisition blood pressure of a patient at an acquisition site and an oxygen saturation signal indicative of an oxygen saturation of the patient. The processing circuitry may determine a cerebral autoregulation status value based on the blood pressure signal and the oxygen saturation signal. The processing circuitry may determine a non-cerebral autoregulation status value based on the cerebral autoregulation status value and an adjustment value. The processing circuitry provide to an output device a signal indicative of the non-cerebral autoregulation status value and a signal indicative of the cerebral autoregulation status value to enable a clinician to monitor the autoregulation status of the patient.

公开(公告)号：US20250031978A1

公开(公告)日：2025-01-30

申请号：US18913051

申请日：2024-10-11

Applicant: COVIDIEN LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Andre Antunes

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/021 ,  A61B5/145 ,  A61B5/20

Abstract: In some examples, a system is configured to determine a non-cerebral autoregulation status value of a patient using machine learning. In some examples, processing circuitry of the system is configured to determine, using a neural network algorithm that has been trained via machine learning training, an individualized adjustment value that is individualized for the patient, including inputting physiological data associated with the patient. The processing circuitry may determine a non-cerebral autoregulation status of the patient based on a cerebral autoregulation value of the patient based on the non-cerebral autoregulation status value of the patient and the adjustment value.

公开(公告)号：US20250009252A1

公开(公告)日：2025-01-09

申请号：US18755304

申请日：2024-06-26

Applicant: Covidien LP

Inventor： Andre Antunes ,  Dean Montgomery ,  Paul S. Addison ,  Philip C. Smit

IPC: A61B5/08 ,  A61B5/00 ,  A61B5/091

Abstract: Methods for improving the accurate determination of respiratory rate, the respiratory rate being measured or monitored from depth measurements from a non-contact monitoring system. The methods include analyzing a waveform obtained from a respiratory parameter and discarding data that does not meet criteria. The respiratory rate may be obtained from an original waveform, a processed waveform, or from a power spectrum derived from the original or processed waveform.

公开(公告)号：US20240057904A1

公开(公告)日：2024-02-22

申请号：US18497827

申请日：2023-10-30

Applicant: COVIDIEN LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Andre Antunes

IPC: A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14553 ,  A61B5/7264

Abstract: In some examples, a system is configured to determine, using a neural network algorithm of a cerebral autoregulation model, a cerebral autoregulation status of the patient based at least in part on a blood pressure of the patient over a period of time and regional cerebral oxygen saturation of the patient over the period of time.

公开(公告)号：US11877868B2

公开(公告)日：2024-01-23

申请号：US18052516

申请日：2022-11-03

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Philip Smit ,  André Antunes ,  Dean Montgomery

IPC: A61B5/00 ,  G08B21/18 ,  G08B29/20 ,  A61B5/1455 ,  G16H50/30 ,  G06N3/08

CPC classification number: A61B5/7275 ,  A61B5/14552 ,  A61B5/7264 ,  A61B5/7282 ,  A61B5/746 ,  G06N3/08 ,  G08B21/182 ,  G08B29/20 ,  G16H50/30 ,  A61B5/0022 ,  A61B5/6826

Abstract: Implementations described herein disclose a method of classifying oxygen level desaturation events. In one implementation, the method includes receiving input signal sequences, the input signals indicative of a physiological condition of a patient, generating an input sequence of oxygen saturation levels based on the input signal sequence, comparing the input sequence of oxygen saturation levels to a desaturation alarm threshold to determine a desaturation event, generating an input feature matrix based on at least one of the input signal sequences and the input sequence of oxygen saturation levels, and classifying based on the input feature matrix, using a neural network, the desaturation event being a severe desaturation event (SDE) or a non-severe desaturation event (non-SDE).

公开(公告)号：US11653840B2

公开(公告)日：2023-05-23

申请号：US16675394

申请日：2019-11-06

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James N. Watson ,  Dean Montgomery

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/02 ,  G16H40/63 ,  G16H50/30 ,  G16H50/20 ,  A61B5/021 ,  A61B5/026 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/03

CPC classification number: A61B5/0205 ,  A61B5/021 ,  A61B5/026 ,  A61B5/02028 ,  A61B5/14546 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/7246 ,  A61B5/742 ,  A61B5/743 ,  A61B5/7425 ,  G16H40/63 ,  G16H50/20 ,  G16H50/30 ,  A61B5/0059 ,  A61B5/0261 ,  A61B5/031

Abstract: A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.