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公开(公告)号：US5797940A
公开(公告)日：1998-08-25
申请号：US866172
申请日：1997-05-30
IPC分类号： A61B17/32
CPC分类号： A61B17/32093 , A61B5/150022 , A61B5/15019 , A61B5/150259 , A61B5/150427 , A61B5/150916 , A61B5/15113 , A61B5/15128 , A61B5/15144
摘要： A device for making an adjustably sized incision in skin. The device comprises a housing having a slotted opening; a blade disposed within the housing for making an incision in skin; a blade triggering mechanism disposed within the housing, for propelling the blade through the slotted opening of the housing a given distance to make an incision of a predetermined size in the skin; and incision size adjusting mechanism associated with the housing for selectively adjusting the size of the incision. The incision size adjusting mechanism includes a cam disposed within the housing, the cam being manually movable relative to the housing for allowing the size of the incision to be adjusted by variably limiting the given distance the blade is propelled through the slotted opening of the housing according to the cam's position relative to the housing. In one embodiment, the cam adjusts the size of the incision by varying the incision's depth into the skin to produce blood sample volumes which are selectively increased or decreased according to a selected depth of the incision. This feature makes the device especially suitable for making skin incisions in adults or children. In another embodiment, the cam adjusts the size of the incision by varying the incision's depth into the skin and the incision's length in the skin to produce blood sample volumes which are selectively increased or decreased according to a selected depth and length of the incision. This feature makes the device especially suitable for making skin incisions in infants and toddlers.
摘要翻译： 用于在皮肤中制作可调节尺寸的切口的装置。 该装置包括具有开槽开口的壳体; 设置在所述壳体内用于在皮肤中形成切口的刀片; 刀片触发机构，其设置在所述壳体内，用于通过所述壳体的开槽开口推动所述刀片给定距离以在皮肤中切割预定尺寸; 以及与壳体相关联的切口尺寸调节机构，用于选择性地调节切口的尺寸。 所述切口尺寸调节机构包括设置在所述壳体内的凸轮，所述凸轮可手动地相对于所述壳体移动，以允许通过可变地限制所述刀片通过所述壳体的开槽开口被推进的给定距离来调节所述切口的尺寸， 到凸轮相对于壳体的位置。 在一个实施例中，凸轮通过改变切口进入皮肤的深度来调节切口的尺寸，以产生根据切口的选定深度选择性地增加或减少的血液样本体积。 该功能使得该装置特别适合于在成人或儿童中进行皮肤切口。 在另一个实施例中，凸轮通过改变切口在皮肤中的深度和皮肤中的切口长度来调节切口的尺寸，以产生根据切口的所选深度和长度选择性地增加或减少的血液样本体积。 该特征使得该装置特别适用于在婴儿和幼儿中进行皮肤切口。
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公开(公告)号：US5518006A
公开(公告)日：1996-05-21
申请号：US287828
申请日：1994-08-09
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150267 , A61B5/150343 , A61B5/150442 , A61B5/15144 , A61B5/150305
摘要： A blood sampling and transferring device including a disposable auto-pricking lancet and a reservoir integrated together for creating a skin incision and collecting a blood sample therefrom in a one-step operation. The reservoir is preferably funnel shaped with a large opening at one end for receiving the blood sample from the patient, and a small opening at the other end which is small enough to prevent unassisted passage of the collected blood therethrough. The blood sample can then be temporarily stored until such time as the sampling device is engaged with a blood testing device that has an aperture to accommodate the small opening of the reservoir and a pump to draw the blood from the reservoir for testing.
摘要翻译： 一种血液采集和传送装置，包括一次性自动穿刺刺血针和集成在一起的用于创建皮肤切口并且以一步操作收集血液样本的储存器。 储存器优选为漏斗形，其一端具有大的开口，用于接收来自患者的血液样本，另一端的小开口足够小以防止所收集的血液不通过其通过。 然后可以临时存储血液样本，直到采样装置与具有孔的血液检查装置接合以适应容器的小开口的时间以及从储存器抽取血液以进行测试的泵。
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公开(公告)号：US5496009A
公开(公告)日：1996-03-05
申请号：US319918
申请日：1994-10-07
CPC分类号： F16K99/0001 , F15C3/04 , F15C5/00 , F16K7/17 , F16K99/0015 , F16K99/0059 , F16K2099/008 , F16K2099/0084 , F16K2099/0086
摘要： A valve comprises a first rigid layer having a substantially planar first surface, a second rigid layer having a substantially planar second surface facing the first surface and a substantially planar third surface opposite the second surface and a flexible layer positioned between the first and second surfaces. A valve chamber is demarcated by a concave surface in the substantially planar first surface and one surface of the flexible layer and at least one first fluid passageway in the first rigid layer opens into the valve chamber at the concave surface to alternatively apply a vacuum and pressure thereto. A fluid chamber is demarcated by another surface of the flexible layer and a concave-convex surface in the substantially planar second surface which comprises an inner circular convex portion and a concentric annular outer concave portion. At least two second fluid passageways in the second rigid layer open into the valve chamber at the convex surface. When a vacuum is applied to the valve chamber, the flexible layer flexes to space the other surface of the flexible layer apart from the concave-convex surface to permit communication between the at least two second fluid passageways and when a pressure is applied to the valve chamber, the flexible layer flexes to dispose the other surface of the flexible layer on the concave-convex surface to prevent communication between the at least two second fluid passageways.
摘要翻译： 阀包括具有基本上平面的第一表面的第一刚性层，具有面向第一表面的基本平坦的第二表面的第二刚性层和与第二表面相对的基本平坦的第三表面以及位于第一表面和第二表面之间的柔性层。 阀室由基本平坦的第一表面和柔性层的一个表面中的凹表面划分，并且第一刚性层中的至少一个第一流体通道在凹表面处打开到阀室中，以交替地施加真空和压力 到此。 流体室由柔性层的另一个表面和基本平坦的第二表面中的凹凸表面划分，其包括内圆形凸部和同心环形外凹部。 第二刚性层中的至少两个第二流体通道在凸表面处进入阀室。 当向阀室施加真空时，柔性层挠曲以使柔性层的另一个表面与凹凸表面隔开，以允许至少两个第二流体通道之间的连通，并且当压力施加到阀 柔性层弯曲以将柔性层的另一表面设置在凹凸表面上，以防止至少两个第二流体通道之间的连通。
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公开(公告)号：US5836360A
公开(公告)日：1998-11-17
申请号：US823973
申请日：1997-03-25
申请人： Michael Gavin , James A. Mawhirt
发明人： Michael Gavin , James A. Mawhirt
CPC分类号： B01L3/508 , G01F19/00 , B01L2200/12 , B01L2400/0406
摘要： A volume-control receptacle has a reservoir with a bottom. The reservoir is adapted for receiving a fluid. The receptacle has a plurality of capillaries opening on the reservoir at a specific height above the bottom; the capillaries draw off the excess fluid from the receptacle, thereby leaving a specific amount of fluid in the reservoir. In a preferred embodiment, the volume-control receptacle is adapted for use with a disposable cuvette. The reservoir of the receptacle has a drain at the bottom connected to the cuvette for delivering the fluid to a testing instrument or other final application point. The volume-control receptacle has a lip projecting upward from a promontory of the receptacle. A rib extends downward from the lip to the bottom of the reservoir for guiding the fluid into the reservoir.
摘要翻译： 容积控制容器具有底部的容器。 容器适于接收流体。 容器具有在底部上方的特定高度处在储存器上开口的多个毛细管; 毛细管从容器中排出多余的液体，从而在容器中留下特定量的流体。 在优选实施例中，音量控制插座适于与一次性比色皿一起使用。 容器的储存器在底部具有连接到反应杯的排水口，用于将流体输送到测试仪器或其他最终施加点。 音量控制插座具有从插座的岬向上突出的唇部。 肋条从储存器的唇缘向底部延伸到底部，以将流体引导到储存器中。
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公开(公告)号：US5669764A
公开(公告)日：1997-09-23
申请号：US549958
申请日：1995-10-30
CPC分类号： G01N35/1095 , F04B43/06 , F04B53/1057 , Y10S417/01
摘要： An integral valve diaphragm pump has a first rigid layer, a second rigid layer and a flexible membrane therebetween. Concave surfaces in the two rigid layers form a pump. The pump includes an actuating chamber which is alternately connected to a source of pressure and a source of vacuum. A pump chamber is connected to a fluid source and a fluid receiver through a filling check valve and a dispensing check valve, respectively. Duckbill and spring loaded ball check valves are disclosed.
摘要翻译： 一体式阀隔膜泵具有第一刚性层，第二刚性层和其间的柔性膜。 两个刚性层中的凹面形成泵。 该泵包括一个致动室，该致动室交替地连接到一个压力源和一个真空源。 泵室分别通过填充止回阀和分配单向阀连接到流体源和流体接收器。 公开了鸭嘴和弹簧加载的球止回阀。
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16.发明授权Portable prothrombin time test apparatus and associated method of performing a prothrombin time test 失效便携式凝血酶原时间检测装置及其相关方法进行凝血酶原时间检测
公开(公告)号：US5591403A
公开(公告)日：1997-01-07
申请号：US617296
申请日：1996-03-18
申请人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
发明人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino , Albert Simone
CPC分类号： G01N33/4905 , G01N33/86 , Y10T436/10
摘要： A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined degree of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing control agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.
摘要翻译： 一种用于对患者血液进行凝血测试的便携式装置。 首先使用刺血针从患者抽血。 然后将血液供应到放置在测试装置内的一次性比色皿。 血液被吸入比色皿内的多个管道。 每个管道含有由血液再水合的干燥或冻干的活化剂。 每个导管中的血液然后往复运动跨越限制区域，直到发生预定的凝结程度。 由于在多个管道中监测凝固时间，因此可以确定给定样品的凝固时间。 在至少一个导管中存在归一化控制剂。 归一化控制剂抵抗血液样品中存在的抗凝血剂的任何作用，从而允许血液样品具有大致正常的凝血特性。 与未处理的血液同时测试归一化的血液，以提供参考值，可以判断测试系统的功能和样品的质量。
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公开(公告)号：US5137693A
公开(公告)日：1992-08-11
申请号：US559366
申请日：1990-07-30
申请人： James A. Mawhirt
发明人： James A. Mawhirt
CPC分类号： B01L9/06 , B65G2201/0261
摘要： The test tube holder includes an elongated tubular member which supports a pivot member and receives a removable adapter member. The adapter member accommodates a test tube and can be interchanged with another adapter member that accommodates a different size test tube. Biasing springs are provided in the adapter member to hold the test tube therein. The biasing force of the biasing springs against the test tube is predetermined to permit easy insertion and removal of the test tube from the adapter member. The test tube holder which includes the adapter member can be joined to other similar test tube holders in a manner which permits relative pivoting and tilting of one test tube holder with respect to another test tube holder. The test tube holder further includes a detent arrangement for inseparably detenting the adapter member in the tubular member when a test tube is present in the tubular member. Removal of the test tube from the test tube holder enables the adapter member to be separated from the tubular member.
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公开(公告)号：US5797921A
公开(公告)日：1998-08-25
申请号：US819426
申请日：1997-03-17
IPC分类号： A61B17/00 , A61B17/326 , A61B17/32
CPC分类号： A61B17/326 , A61B2017/0023
摘要： A method for circumcising a penis having a foreskin encircling the glans penis using an apparatus having a cap, a guide clamp, and a blade holder mechanism. The cap defines an interior space and has an outer surface. The glans penis of the penis is placed in the interior space defined by the cap. The foreskin of the penis is positioned around an outer surface of the cap. The clamp is positioned over the foreskin such that a portion of the foreskin is interposed between the clamp and specific features on the outer surface of the cap. The guide clamp is secured in a position over the foreskin of the penis crushing the skin to prevent bleeding. The blade holder mechanism is placed on the guide clamp and rotated around the guide clamp so that a blade carried by the blade holder mechanism cuts the foreskin. The blade is mounted on a flexible finger within the blade holder and as such is exposed for cutting only during use. At all other times the blade is safely contained within the blade holder body.
摘要翻译： 一种使用具有盖帽，引导夹具和刀片保持器机构的装置对具有包围阴茎龟头的包皮的阴茎进行包皮环切的方法。 盖子限定了内部空间并具有外表面。 阴茎的龟头阴茎被放置在由帽子限定的内部空间中。 阴茎的包皮围绕帽的外表面定位。 夹具定位在包皮上，使得一部分包皮插入在夹具和盖的外表面上的特定特征之间。 引导夹固定在阴茎包皮上方的位置，以破坏皮肤以防止出血。 刀片保持器机构被放置在引导夹具上并围绕引导夹具旋转，使得由刀片保持器机构承载的刀片切割包皮。 叶片安装在刀片保持器内的柔性指状物上，并且因此仅在使用期间暴露于切割。 在所有其他时间，刀片被安全地包含在刀片保持器本体内。
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19.发明授权Portable test apparatus and associated method of performing a blood coagulation test 失效便携式试验装置及进行凝血试验的相关方法
公开(公告)号：US5534226A
公开(公告)日：1996-07-09
申请号：US424063
申请日：1995-04-19
申请人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino
发明人： Michael Gavin , Catherine M. Cimini , Ming Huang , Anthony Kuklo, Jr. , James A. Mawhirt , Eduardo Marcelino
CPC分类号： G01N33/4905 , G01N33/86 , Y10T436/10
摘要： A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined device of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing consol agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.
摘要翻译： 一种用于对患者血液进行凝血测试的便携式装置。 首先使用刺血针从患者抽血。 然后将血液供应到放置在测试装置内的一次性比色皿。 血液被吸入比色皿内的多个管道。 每个管道含有由血液再水合的干燥或冻干的活化剂。 然后，每个导管中的血液往复运动跨越限制区域，直到发生凝固的预定装置。 由于在多个管道中监测凝固时间，因此可以确定给定样品的凝固时间。 在至少一个导管中存在归一化控制剂。 归一化调理剂抵消血液样品中存在的抗凝血剂的任何影响，从而允许血液样品具有大致正常的凝血特性。 与未处理的血液同时测试归一化的血液，以提供参考值，可以判断测试系统的功能和样品的质量。
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公开(公告)号：US4944924A
公开(公告)日：1990-07-31
申请号：US61252
申请日：1987-06-11
CPC分类号： B01L9/06 , G01N35/021
摘要： The test tube holder includes an elongated tubular member which supports a pivot member thereby rendering the tubular member and pivot member relatively pivotable with respect to each other. Latch members provided on the tubular member and pivot member are engagable with complementary shaped latch members of other test tube holders to form a linkage. The pivotal relationship between the tubular member and the pivot member permit pivotal movement of one test tube holder with respect to the longitudinal axis of another test tube holder. A pivotal connection between the latch members of adjacent test tube holders also permits tilting of one test tube holder with respect to another test tube holder in the linkage. An adapter member for holding test tubes is insertable in the tubular member and pivot member assembly. The adapter member accommodates one size test tube and can be interchanged with another adapter member that accommodates another size test tube. Thus, the linkage of test tube holders can include test tubes of different size. The relative pivotal movement between test tube holders in the linkage permits stacking of the linkage in a fan-fold arrangement. The tilting movement between test tube holders in a linkage permits mixing of the contents of a test tube or a group of test tubes independent of all others in the linkage before a sample is tested. Under this arrangement, a linkage of test tubes of unlimited length can be provided.
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