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公开(公告)号：US20120213831A1
公开(公告)日：2012-08-23
申请号：US13462004
申请日：2012-05-02
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
IPC: A61K9/14 , A61K31/4375 , A61K49/18 , A61K31/704 , A61P35/00 , B82Y5/00 , B82B1/00
CPC classification number: A61K9/1635 , A61K31/715 , A61K45/06 , A61L2430/36 , Y10T428/2982
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
Abstract translation: 本发明涉及包含生物相容的，可溶胀的，基本上亲水的，无毒的和基本上为球形的聚合物材料载体的可注射组合物，其能够有效地输送用于栓塞药物治疗的生物活性治疗因子。 本发明还涉及使用可注射组合物的栓塞基因治疗方法，特别是用于治疗血管生成和非血管生成依赖性疾病的方法。
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公开(公告)号：US08142815B2
公开(公告)日：2012-03-27
申请号：US10919257
申请日：2004-08-17
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further relates to methods of dermal augmentation, particularly for the treatment of skin contour deficiencies, using the injectable compositions.
Abstract translation: 本发明涉及可注射组合物，其包含生物相容性，可溶胀，亲水，无毒和基本上为球形的微球微球和用于皮肤增生的生物相容性载体。 本发明还涉及使用可注射组合物的皮肤增强方法，特别是用于治疗皮肤轮廓缺陷的方法。
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公开(公告)号：US20090186094A1
公开(公告)日：2009-07-23
申请号：US12197187
申请日：2008-08-22
Applicant: Jean-Marie Vogel , Egisto Boschetti , Richard Thomas
Inventor： Jean-Marie Vogel , Egisto Boschetti , Richard Thomas
IPC: A61K9/14
CPC classification number: A61K9/14 , A61K31/78 , A61K31/785 , A61L27/3804 , A61L27/3839 , A61L27/50 , A61L31/005 , A61L31/14 , A61L2400/06
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.
Abstract translation: 本发明涉及包含可用于组织膨胀的生物相容性，可溶胀，亲水，无毒和基本上为球形的微球的可注射组合物。 本发明还涉及使用可注射组合物的组织膨胀方法，特别是用于治疗胃食管反流病，尿失禁或尿反流疾病的方法。
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公开(公告)号：US20080220077A1
公开(公告)日：2008-09-11
申请号：US12122590
申请日：2008-05-16
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
CPC classification number: A61K9/1635 , A61K31/715 , A61K45/06 , A61L2430/36 , Y10T428/2982
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
Abstract translation: 本发明涉及包含生物相容的，可溶胀的，基本上亲水的，无毒的和基本上为球形的聚合物材料载体的可注射组合物，其能够有效地输送用于栓塞药物治疗的生物活性治疗因子。 本发明还涉及使用可注射组合物的栓塞基因治疗方法，特别是用于治疗血管生成和非血管生成依赖性疾病的方法。
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公开(公告)号：US20080118569A1
公开(公告)日：2008-05-22
申请号：US12009181
申请日：2008-01-16
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
CPC classification number: A61L27/3834 , A61K9/0024 , A61K9/08 , A61K9/1635 , A61K9/1658 , A61K9/167 , A61K35/12 , A61K35/28 , A61K35/34 , A61K35/36 , A61L2400/06 , C12N5/0075 , C12N2533/30
Abstract: The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.
Abstract translation: 本发明涉及包含与用于组织构建和产生的干细胞相关的生物相容性，亲水性，无毒性和基本上为球形的微球的可注射组合物。 本发明还涉及使用可注射组合物来治疗各种组织损伤和缺陷的组织结构和产生方法。
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Patent Agency Ranking
公开(公告)号：US06660301B1
公开(公告)日：2003-12-09
申请号：US09528991
申请日：2000-03-20
Applicant: Jean-Marie Vogel , Richard Thomas , Egisto Boschetti
Inventor： Jean-Marie Vogel , Richard Thomas , Egisto Boschetti
IPC: A61K914
CPC classification number: A61K9/14 , A61K9/0019 , A61K9/16 , A61K9/1635 , A61K9/1641 , A61K31/78 , A61K31/785 , A61K47/6925 , A61K47/6927 , A61K49/0442 , A61K49/048 , A61L27/38 , A61L27/50 , A61L31/005 , A61L31/14 , A61L2400/06
Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.
Abstract translation: 本发明涉及用于真皮增生和组织膨胀的弹性，亲水和基本上球形的微球。 本发明提供了包含微球和用于真皮增生的生物相容性载体的可注射组合物。 本发明还提供使用可注射组合物的皮肤增强和组织膨胀的方法，特别是用于治疗皮肤轮廓缺陷，胃食管反流病，尿失禁和尿反流疾病的方法。
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公开(公告)号：US10265271B2
公开(公告)日：2019-04-23
申请号：US12122590
申请日：2008-05-16
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
IPC: A61K9/16 , A61K31/715 , A61K45/06
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
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公开(公告)号：US08778333B2
公开(公告)日：2014-07-15
申请号：US12009181
申请日：2008-01-16
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
IPC: A61K35/12 , A61K9/14 , A61K9/50 , A61F2/02 , C12N11/08 , C12N5/071 , C12N5/074 , C12N5/0775 , C12N5/07
CPC classification number: A61L27/3834 , A61K9/0024 , A61K9/08 , A61K9/1635 , A61K9/1658 , A61K9/167 , A61K35/12 , A61K35/28 , A61K35/34 , A61K35/36 , A61L2400/06 , C12N5/0075 , C12N2533/30
Abstract: The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.
Abstract translation: 本发明涉及包含与用于组织构建和产生的干细胞相关的生物相容性，亲水性，无毒性和基本上为球形的微球的可注射组合物。 本发明还涉及使用可注射组合物来治疗各种组织损伤和缺陷的组织结构和产生方法。
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公开(公告)号：US20120141379A1
公开(公告)日：2012-06-07
申请号：US13371964
申请日：2012-02-13
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
CPC classification number: A61K9/1635 , A61K31/715 , A61K45/06 , A61L2430/36 , Y10T428/2982
Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
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公开(公告)号：US07338657B2
公开(公告)日：2008-03-04
申请号：US10220984
申请日：2001-03-15
Applicant: Jean-Marie Vogel , Egisto Boschetti
Inventor： Jean-Marie Vogel , Egisto Boschetti
CPC classification number: A61L27/3834 , A61K9/0024 , A61K9/08 , A61K9/1635 , A61K9/1658 , A61K9/167 , A61K35/12 , A61K35/28 , A61K35/34 , A61K35/36 , A61L2400/06 , C12N5/0075 , C12N2533/30
Abstract: The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.
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