公开(公告)号：US4391912A

公开(公告)日：1983-07-05

申请号：US188416

申请日：1980-09-18

申请人： Koichi Yoshida ,  Fusakazu Hayano

发明人： Koichi Yoshida ,  Fusakazu Hayano

IPC分类号： C12M3/02 ,  C12M3/06 ,  C12N5/02 ,  C12N5/06 ,  C12M3/00

CPC分类号： C12M29/16 ,  C12M25/10

摘要： A method of cultivating floating animal cells, such as lymphocytic cells, medullary tumor cells, medullary tumor cells obtained by the cell fusion with other cells, lymphoma cells, leukemic cells, leukocytic cells, mastocarcinoma cells, liver cancer cells, etc., which comprises introducing a culture medium in a cell culture unit comprising a shell and a plurality of hollow fibers enclosed in the shell, said hollow fiber being open at either end outside of the shell and having a pore diameter of from about 20 A to 10.sup.5 A, wherein the culture medium passes through the interior of the hollow fibers and the floating animal cells are cultivated in the space between the shell and the hollow fibers is disclosed. A floating animal cell culture unit for the method is also disclosed.

摘要翻译： 通过与其他细胞，淋巴瘤细胞，白血病细胞，白细胞细胞，乳腺癌细胞，肝癌细胞等的细胞融合获得的培养浮游动物细胞的方法，例如淋巴细胞，髓质肿瘤细胞，髓质肿瘤细胞，其包含 在细胞培养单元中引入培养基，所述细胞培养单元包括壳和围绕在壳中的多个中空纤维，所述中空纤维在壳外部的任一端开口并具有约20A至105A的孔径，其中 培养基通过中空纤维的内部，并且在壳和中空纤维之间的空间中培养浮动的动物细胞。 还公开了用于该方法的浮动动物细胞培养单元。

公开(公告)号：US4381397A

公开(公告)日：1983-04-26

申请号：US233414

申请日：1981-02-11

申请人： Koichi Yoshida ,  Toshiyuki Iwaisako ,  Junzo Masamoto ,  Katsuhiko Hamanaka ,  Hajime Komaki

发明人： Koichi Yoshida ,  Toshiyuki Iwaisako ,  Junzo Masamoto ,  Katsuhiko Hamanaka ,  Hajime Komaki

IPC分类号： B01J23/00 ,  B01J23/22 ,  B01J23/28 ,  B01J23/30 ,  B01J27/00 ,  B01J27/18 ,  C07B61/00 ,  C07D323/06

CPC分类号： C07D323/06

摘要： A method for synthesizing trioxane by heating and reacting an aqueous formaldehyde solution in the presence of a heteropolyacid. As the heteropolyacid, there is preferably used one that contains, as a coordinating element or coordinating elements, W, Mo, V or Nb alone or two or more of them.

公开(公告)号：US08662437B2

公开(公告)日：2014-03-04

申请号：US12680130

申请日：2007-09-25

申请人： Keitaro Harada ,  Masayoshi Yokoo ,  Koichi Yoshida ,  Akio Murakami

发明人： Keitaro Harada ,  Masayoshi Yokoo ,  Koichi Yoshida ,  Akio Murakami

IPC分类号： B65H59/04

CPC分类号： B65H59/04 ,  B65H59/043 ,  B65H59/387 ,  H01L31/022425 ,  Y02E10/50

摘要： When current collecting wires are laid in parallel with each other on a solar cell on which a photosensitive film is formed, a wire tension adjusting mechanism is provided which includes a bobbin holder shaft pivotally held on the side of a frame in a bobbin cassette in a wiring apparatus and a wire bobbin is detachably fixed on the bobbin holder shaft. The wire tension adjusting mechanism further includes a pre-load means for adjusting the torque of the bobbin holder shaft and the tension of each current collecting wire to be drawn out from the wire bobbin held by the bobbin shaft is adjusted.

摘要翻译： 当集电线在形成有感光膜的太阳能电池上彼此平行放置时，提供了一种线张力调节机构，其包括在筒管盒中的框架侧枢转地保持的筒管架轴 接线装置和线架可拆卸地固定在筒管架轴上。 线张力调节机构还包括用于调节筒管架轴的扭矩的预加载装置，并且调节从由筒管轴保持的线筒引出的每个集流线的张力。

公开(公告)号：US08156827B2

公开(公告)日：2012-04-17

申请号：US12403437

申请日：2009-03-13

申请人： Koichi Yoshida

发明人： Koichi Yoshida

IPC分类号： G01L1/04

CPC分类号： G01P15/123 ,  G01P15/0802 ,  G01P2015/0828

摘要： An external force detection device includes a weight portion, a supporting portion, and a beam portion provided in an SOI substrate which includes an upper layer and a lower layer that are capable of being etched with a first etching gas and sandwich an intermediate layer that is capable of being etched with a second etching gas. The weight portion is displaced in accordance with an external force to cause the beam portion to deform. The upper layer in a gap portion between the weight portion and the supporting portion is etched. The lower layer in the gap portion and the lower layer below the beam portion are etched. The intermediate layer in the gap portion is then etched. The groove formed by etching the upper layer has a multidirectional two-dimensional shape.

摘要翻译： 外力检测装置包括配重部分，支撑部分和设置在SOI衬底中的梁部分，该衬底包括能够用第一蚀刻气体蚀刻的上层和下层，并夹着中间层， 能够用第二蚀刻气体进行蚀刻。 重物部分根据外力而移位，使梁部变形。 在重量部分和支撑部分之间的间隙部分中的上层被蚀刻。 蚀刻间隙部分中的下层和光束部分下方的下层。 然后蚀刻间隙部分中的中间层。 通过蚀刻上层形成的凹槽具有多向二维形状。

公开(公告)号：US20110262453A1

公开(公告)日：2011-10-27

申请号：US13059931

申请日：2009-08-20

申请人： Samir E. Witta ,  Koichi Yoshida ,  Rafal Dziadziuszko ,  Fred R. Hirsch

发明人： Samir E. Witta ,  Koichi Yoshida ,  Rafal Dziadziuszko ,  Fred R. Hirsch

IPC分类号： A61K39/395 ,  A61P35/00 ,  A61K38/45 ,  C12Q1/02

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/57484 ,  G01N2333/705 ,  G01N2333/71 ,  G01N2800/52

摘要： The present invention relates to a method of predicting response of a cancer cell tissue to IGF-IR treatment. The inventors have observed a direct relationship between the expression of survivin, ErbB3 and E-cadherin and the response of cancer cells to IGF-IR treatment. This observation permits screening of tumor cells prior to treatment to determine whether the cancer will respond to IGF-IR treatment, and/or to monitor the efficacy of such a treatment by conducting “before and after” assessments of the expression of these markers

摘要翻译： 本发明涉及预测癌细胞组织对IGF-1R治疗的反应的方法。 本发明人观察到存活蛋白，ErbB3和E-钙粘蛋白的表达与癌细胞对IGF-1R处理的反应之间存在直接关系。 该观察允许在治疗之前筛选肿瘤细胞以确定癌症是否将响应于IGF-1R治疗，和/或通过对这些标记物的表达进行“前后”评估来监测这种治疗的功效

公开(公告)号：US07315110B2

公开(公告)日：2008-01-01

申请号：US11167912

申请日：2005-06-28

申请人： Koichi Yoshida

发明人： Koichi Yoshida

IPC分类号： H01T13/20

CPC分类号： H01T13/38 ,  H01T13/20

摘要： A spark plug according to the invention has a length and an outer side surface. The outer side surface includes a plurality of closed band-shaped regions arranged in the lengthwise direction of the spark plug, within each of which a plurality of identical marks, which represent the same piece of information concerning the spark plug, are formed at predetermined intervals in a circumferential direction of the spark plug. Further, the marks within each of the regions represent the piece of information different from that represented by the marks within any other one of the regions, and each of the marks within each of the regions is aligned in the lengthwise direction of the spark plug with one of the marks within any other one of the regions. With such formation of marks, the spark plug can be accurately identified without rotating it to a specific position during the identification process.

摘要翻译： 根据本发明的火花塞具有长度和外侧表面。 外侧表面包括沿着火花塞的长度方向布置的多个封闭带状区域，其中分别形成表示与火花塞相关的信息的多个相同的标记，并以预定间隔形成 在火花塞的圆周方向上。 此外，每个区域内的标记表示与该区域内的标记不同的信息，并且每个区域内的每个标记在火花塞的长度方向上对齐， 任何其他地区之一的标记之一。 通过这种标志的形成，可以在识别过程中将火花塞精确地识别而不将其旋转到特定位置。

公开(公告)号：US07275551B2

公开(公告)日：2007-10-02

申请号：US10258526

申请日：2001-04-12

申请人： Takafumi Kanaya ,  Kazuhisa Okada ,  Koichi Yoshida

发明人： Takafumi Kanaya ,  Kazuhisa Okada ,  Koichi Yoshida

IPC分类号： B08B3/00 ,  B08B3/06

CPC分类号： A23L3/3409 ,  A23B7/157 ,  A23B7/158 ,  A23B9/30 ,  A23L3/358 ,  A23L3/3589 ,  A23N12/02 ,  Y02A40/922

摘要： A food washing apparatus of the invention includes an ozonized water generator (10), a cylindrical washing tank (1) in which the food materials are put and which can rotate to wash the food materials, a drainage part (4) formed at a part of the washing tank (1) and including openings to such a degree that water passes through and the food materials do not pass through, and wash water pipings (2, 9) which are inserted and disposed in the washing tank (1) in an axial direction and in which water spray holes (2a, 2a) for spraying wash water including at least ozonized water are formed, and while at least one part of the wash water sprayed from the wash water pipings (2, 9) is draind from the washing tank (1) every rotation of the washing tank (1), washing of the food materials is performed. Further, there is also a method in which a receiving tank (8) for wash water drained from the washing tank (1) is provided, and at least one part of the wash water in the receiving tank (8) is returned to an inlet side of the ozonized water generator (10) to perform cyclic use of the wash water.

摘要翻译： 本发明的饮食洗涤装置包括臭氧水发生器（10），其中放置食物材料并可旋转以洗涤食物的圆筒形洗涤罐（1），形成在部分上的排出部分（4） 并且包括开口，使得水通过并且食品材料不通过的程度，并且将洗涤槽（1）中插入和设置的水管（2,9）清洗在 并且其中形成用于喷射包括至少臭氧化水的洗涤水的喷水孔（2a，2a），并且在从洗涤水管道（2,9）喷射的洗涤水的至少一部分被排出 从清洗槽（1）洗涤槽（1）旋转一周后，进行食品的清洗。 此外，还提供了一种从洗涤槽（1）排出的用于洗涤水的接收罐（8）的方法，并且容纳罐（8）中的洗涤水的至少一部分返回到入口 臭氧化水发生器（10）的一侧以循环使用洗涤水。

公开(公告)号：US20070216278A1

公开(公告)日：2007-09-20

申请号：US11717788

申请日：2007-03-14

申请人： Koichi Yoshida

发明人： Koichi Yoshida

IPC分类号： H01T13/20

CPC分类号： H01T13/20 ,  H01T13/32 ,  H01T13/36 ,  H01T13/39

摘要： A spark plug is disclosed as having a metal shell, a porcelain insulator fixedly secured to the metal shell, a center electrode and a ground electrode providing a spark discharge gap with the center electrode. The porcelain insulator has a through-bore partially exposed from an end face of the ground electrode in a surface area S1, as viewed from a distal end of the spark plug, and having a total surface area S2 falling in the relationship S1/S2≦0.3. The center electrode protrudes from the porcelain insulator with a protruding length L under the relationship L≦0.6 mm. A minimal value Hmin and a maximal value Hmax in distance between the ground electrode and the end face of the porcelain insulator lies in the relationship Hmax/Hmin≦1.3. Wall thickness T between the through-bore and an outer periphery of the porcelain insulator lies in the relationship T≦0.7 mm.

摘要翻译： 公开了一种火花塞，其具有金属壳，固定在金属壳上的瓷绝缘体，中心电极和与中心电极提供火花放电间隙的接地电极。 陶瓷绝缘体从火花塞的远端观察时，在表面区域S1中从接地电极的端面部分地露出贯通孔，总表面积S 2处于关系S 1 / S 2 <= 0.3。 中心电极以L <= 0.6mm的关系从瓷绝缘体突出长度为L。 接地电极与陶瓷绝缘体端面之间的距离最小值Hmin和最大值Hmax在Hmax / Hmin <= 1.3之间。 通孔与陶瓷绝缘体的外周之间的壁厚T在T <= 0.7mm的关系中。

公开(公告)号：US20050191838A1

公开(公告)日：2005-09-01

申请号：US11114084

申请日：2005-04-26

申请人： Shoriki Narita ,  Koichi Yoshida ,  Masahiko Ikeya ,  Takaharu Mae ,  Shinji Kanayama ,  Makoto Imanishi ,  Kazushi Higashi ,  Kenji Fukumoto ,  Hiroshi Wada

发明人： Shoriki Narita ,  Koichi Yoshida ,  Masahiko Ikeya ,  Takaharu Mae ,  Shinji Kanayama ,  Makoto Imanishi ,  Kazushi Higashi ,  Kenji Fukumoto ,  Hiroshi Wada

IPC分类号： H05K3/34 ,  B23K20/00 ,  H01L21/00 ,  H01L21/60 ,  H01L21/44

CPC分类号： H01L24/742 ,  H01L21/67138 ,  H01L21/67144 ,  H01L21/67248 ,  H01L24/11 ,  H01L2224/05568 ,  H01L2224/05573 ,  H01L2224/1134 ,  H01L2224/13099 ,  H01L2224/13144 ,  H01L2224/45144 ,  H01L2924/01004 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01023 ,  H01L2924/01025 ,  H01L2924/01033 ,  H01L2924/01039 ,  H01L2924/01047 ,  H01L2924/01052 ,  H01L2924/01065 ,  H01L2924/01073 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01327 ,  H01L2924/10329 ,  H01L2924/351 ,  Y10T29/4921 ,  H01L2924/00 ,  H01L2924/00014

摘要： A preheat device (160) is provided to execute, before forming bumps (16) to electrode parts (15), a pre-formation temperature control for bonding promotion to promote bonding between the electrode parts and the bumps during bump formation. Metal particles of the electrode parts can be changed to an appropriate state before the bump formation. Phenomenally, a bonding state between the electrode parts and the bumps can be improved as compared with the conventional art. In a further arrangement of the present invention, semiconductor components with bumps can be heated under a bonding strength improvement condition by a bonding stage (316) through controlling the heating by a controller (317).

摘要翻译： 提供预热装置（160），用于在形成凸起（16）到电极部件（15）之前执行用于粘接促进的预制温度控制，以促进在凸起形成期间电极部件和凸块之间的接合。 电极部分的金属颗粒可以在凸点形成之前变成适当的状态。 与现有技术相比，现在可以改善电极部分和凸块之间的结合状态。 在本发明的另一方面中，通过控制器（317）的加热来控制加热，可以通过接合台（316）在接合强度改善条件下加热具有凸块的半导体部件。

公开(公告)号：US06481616B2

公开(公告)日：2002-11-19

申请号：US09978872

申请日：2001-10-17

申请人： Makoto Imanishi ,  Akihiro Yamamoto ,  Hiroyuki Otani ,  Shinzo Eguchi ,  Takahiro Yonezawa ,  Kazushi Higashi ,  Koichi Yoshida ,  Kouji Hirotani

发明人： Makoto Imanishi ,  Akihiro Yamamoto ,  Hiroyuki Otani ,  Shinzo Eguchi ,  Takahiro Yonezawa ,  Kazushi Higashi ,  Koichi Yoshida ,  Kouji Hirotani

IPC分类号： B23K3102

CPC分类号： H01L21/68 ,  H01L21/321 ,  H01L24/11 ,  H01L24/81 ,  H01L2224/13099 ,  H01L2224/45144 ,  H01L2224/81205 ,  H01L2224/81801 ,  H01L2924/01004 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01027 ,  H01L2924/01033 ,  H01L2924/01039 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/14 ,  H01L2924/00

摘要： To eliminate breakage of electronic parts or defective bonding, and enhance reliability of electronic parts, in regulation of electronic parts in bump bonding device. A bump bonding device comprising a stage 1 for mounting and heating an electronic part, and a position regulating device including a rotatable regulating plate 2 having a side for positioning the electronic part, a plate 4 having a side for positioning the electronic part in collaboration with the regulating plate, and a regulating spring 5 for applying a regulating force to the regulating plate in order to press the electronic part to the plate 4.

摘要翻译： 为了消除电子零件的破损或接合不良，提高电子零件的可靠性，在凸块焊接装置中调节电子部件。 一种凸块接合装置，包括用于安装和加热电子部件的台架1和包括具有用于定位电子部件的侧面的可旋转调节板2的位置调节装置，具有用于与电子部件配合的侧面的板4 调节板和用于向调节板施加调节力以便将电子部件按压到板4的调节弹簧5。