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公开(公告)号:US11191944B2
公开(公告)日:2021-12-07
申请号:US16750354
申请日:2020-01-23
Applicant: Magenta Medical Ltd.
Inventor: Yosi Tuval , Zev Sohn , Ehud Schwammenthal , Gad Lubinsky , Victor Troshin , Shaul Jacob Leisner Mustacchi , Yinnon Elisha , Yuri Sudin , Hagit Zemer Harel , Avi Rozenfeld
IPC: A61M1/12 , A61M1/10 , A61M60/148 , A61M60/419 , A61M60/422 , A61M60/818 , A61M60/829 , A61M60/857 , A61M60/896 , A61M60/414 , A61M60/135 , F04D29/52 , F04D29/54 , A61M60/205 , A61M60/122
Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube disposed within the subject's left ventricle. A frame is disposed within the distal portion of the tube. A pump disposed within the frame pumps blood through the tube. A distal-tip element defines a straight proximal portion that defines a longitudinal axis, and a curved distal portion that is shaped such as to curve in a first direction with respect to the longitudinal axis before passing through an inflection point and curving in a second direction with respect to the longitudinal axis, such that the curved distal portion defines a bulge on one side of the longitudinal axis. Other applications are also described.
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公开(公告)号:US20210052794A1
公开(公告)日:2021-02-25
申请号:US17078439
申请日:2020-10-23
Applicant: Magenta Medical Ltd.
Inventor: Yosi Tuval , Zev Sohn , Ehud Schwammenthal , Gad Lubinsky , Victor Troshin , Shaul Mustacchi , Yinnon Elisha , Yuri Sudin , Hagit Zemer Harel , Avi Rozenfeld
Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.
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公开(公告)号:US20210023286A1
公开(公告)日:2021-01-28
申请号:US17069570
申请日:2020-10-13
Applicant: Magenta Medical Ltd.
Inventor: Yosi Tuval , Zev SOHN , Ehud Schwammenthal , Gad Lubinsky
IPC: A61M1/10 , A61B5/0215 , A61M1/12 , F04D3/02 , F04D15/00 , F04D29/041 , F04D29/042 , F04D25/02 , A61B5/042 , F04D29/18 , F04D29/24 , F04D7/00
Abstract: Apparatus and methods are described including a blood pump catheter that includes an axial shaft, and an impeller disposed on the axial shaft. A motor drives the impeller to pump blood, by rotating the impeller. A drive cable extends from the motor to the axial shaft, the drive cable being configured to impart rotational motion from the motor to the impeller by rotating. A distal tip portion is disposed at a distal end of the blood pump catheter. The drive cable, the axial shaft, and the distal tip portion define a continuous lumen therethrough from outside the subject's body to the distal end of the blood pump catheter. The continuous lumen facilitates insertion of the blood pump catheter into the subject's body over a guidewire, and, subsequently, provides a channel through which the purging fluid flows. Other applications are also described.
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公开(公告)号:US20200254161A1
公开(公告)日:2020-08-13
申请号:US16859100
申请日:2020-04-27
Applicant: Magenta Medical Ltd.
Inventor: Ehud Schwammenthal , Yosi Tuval , Daniel Glozman , Tom Shtendel , Gad Lubinsky
Abstract: Apparatus and methods are described, including a blood pump that includes a catheter, a proximal impeller disposed on the catheter inside a proximal impeller housing, and which is configured to pump blood by rotating inside the proximal impeller housing. A distal impeller is disposed on the catheter inside a distal impeller housing, distally to the proximal impeller, and the distal impeller is configured to pump blood by rotating inside the distal impeller housing. A tubular element is disposed between the proximal impeller housing and the distal impeller housing, the tubular element being configured to have a tubular configuration during rotation of the proximal and distal impellers. Other applications are also described.
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公开(公告)号:US20190239998A1
公开(公告)日:2019-08-08
申请号:US16335786
申请日:2017-09-28
Applicant: MAGENTA MEDICAL LTD.
Inventor: Yosi Tuval , Ehud Schwammenthal , Daniel Glozman , Gad Lubinsky
IPC: A61F2/07 , A61B5/0215 , A61B5/00
CPC classification number: A61F2/07 , A61B5/0215 , A61B5/4836 , A61B5/6862 , A61F2/06 , A61F2002/068 , A61F2002/482 , A61F2210/0014 , A61F2230/001 , A61F2250/001 , A61F2250/0039
Abstract: Apparatus and methods are described including a tube (20) that defines a flared downstream portion (30) that diverges toward a downstream end (32) of the tube, and a flared upstream portion (26) that diverges toward an upstream end (28) of the tube, such that a central portion (34) of the tube is narrower than at the ends of the tube. The tube defines a plurality of lateral openings (36). A support frame (24) supports the tube within a subject's vena cava, such that the downstream portion is sealed with respect to the wall of the vena cava downstream of junctions of the vena cava with all of the subject's renal veins, and the upstream portion is sealed with respect to the inner wall of the vena cava upstream of junctions of the vena cava with all of the subject's renal veins. Other applications are also described.
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公开(公告)号:US20190209756A1
公开(公告)日:2019-07-11
申请号:US16278482
申请日:2019-02-18
Applicant: Magenta Medical Ltd.
Inventor: Yosi Tuval , Zev SOHN , Ehud Schwammenthal , Gad Lubinsky
CPC classification number: A61M1/122 , A61B5/0215 , A61B5/042 , A61M1/1008 , A61M1/1013 , A61M1/102 , A61M1/1031 , A61M1/1034 , A61M1/1036 , A61M1/1086 , A61M1/125 , A61M2205/3317 , A61M2205/3327 , A61M2205/3334 , A61M2205/3365 , A61M2205/50 , A61M2230/30 , F04D3/02 , F04D15/0066 , F04D25/02 , F04D29/041 , F04D29/042
Abstract: Apparatus and methods are described including placing a blood pump into a subject's body, the blood pump including an axial shaft, an impeller disposed on the axial shaft, and a drive cable extending from outside the subject's body to the axial shaft. The impeller is driven to pump blood from a distal end of the impeller to a proximal end of the impeller by imparting rotational motion to the impeller via the drive cable, in a given direction of rotation. At least a portion of the drive cable includes a plurality of wires disposed in a coiled configuration that is such that, in response to the drive cable rotating in the given direction of rotation, the plurality of wires disposed in the coiled configuration at least partially unwind, such that the portion of the drive cable shortens axially. Other applications are also described.
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公开(公告)号:US20250099741A1
公开(公告)日:2025-03-27
申请号:US18958196
申请日:2024-11-25
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi Tuval , Zev SOHN , Ehud Schwammenthal , Gad Lubinsky
IPC: A61M60/422 , A61B5/0215 , A61B5/283 , A61M60/13 , A61M60/135 , A61M60/148 , A61M60/174 , A61M60/237 , A61M60/40 , A61M60/414 , A61M60/419 , A61M60/50 , A61M60/531 , A61M60/538 , A61M60/554 , A61M60/806 , A61M60/818 , A61M60/824 , A61M60/825 , A61M60/829 , A61M60/833 , A61M60/857 , A61M60/896 , F04D3/02 , F04D7/00 , F04D15/00 , F04D25/02 , F04D29/041 , F04D29/042 , F04D29/18 , F04D29/24
Abstract: Apparatus and methods are described including deploying a pump head of a left-ventricular assist device in a subject's left ventricle. The pump head includes an axial shaft, and a radially-expandable impeller coupled to the axial shaft. A proximal radial bearing is disposed around the axial shaft proximally to the impeller, and a distal radial bearing is disposed around the axial shaft distally to the impeller. The interface between the axial shaft and the distal radial bearing is purged, by pumping purging fluid into a purging-fluid lumen defined by the left-ventricular assist device. Other applications are also described.
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公开(公告)号:US20250065100A1
公开(公告)日:2025-02-27
申请号:US18947762
申请日:2024-11-14
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi Tuval , Zev Sohn , Ehud Schwammenthal , Gad Lubinsky , Victor Troshin , Shaul Jacob Leisner Mustacchi , Yinnon Elisha , Yuri Sudin , Hagit Zemer Harel , Avi Rozenfeld
IPC: A61M60/148 , A61M60/122 , A61M60/126 , A61M60/13 , A61M60/135 , A61M60/205 , A61M60/216 , A61M60/237 , A61M60/414 , A61M60/419 , A61M60/422 , A61M60/531 , A61M60/804 , A61M60/808 , A61M60/818 , A61M60/825 , A61M60/829 , A61M60/857 , A61M60/894 , A61M60/896 , B05D1/02 , F04D29/38 , F04D29/52 , F04D29/54
Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a frame that includes proximal and distal frame portions that include struts that define cells, and a central frame portion that includes helical struts. An impeller is disposed inside the frame, the impeller being configured to rotate such as to pump blood from a left ventricle of a subject to an aorta of the subject. Other applications are also described.
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公开(公告)号:US12128227B2
公开(公告)日:2024-10-29
申请号:US17528807
申请日:2021-11-17
Applicant: MAGENTA MEDICAL LTD.
Inventor: Yosi Tuval , Yinnon Elisha , David Israeli , Gad Lubinsky , Victor Troshin , Shaul Mustacchi , Yuval Zipory , Avi Rozenfeld , Aurelie Benaddi , Gilad Moiseyev , Yuri Sudin
IPC: A61M60/237 , A61B5/021 , A61B5/0215 , A61M60/13 , A61M60/135 , A61M60/174 , A61M60/178 , A61M60/216 , A61M60/226 , A61M60/414 , A61M60/419 , A61M60/422 , A61M60/523 , A61M60/531 , A61M60/538 , A61M60/546 , A61M60/808 , A61M60/816 , A61M60/818 , A61M60/825 , A61M60/857 , A61M60/865 , A61M60/804 , A61M60/829
CPC classification number: A61M60/237 , A61B5/02141 , A61B5/0215 , A61M60/13 , A61M60/135 , A61M60/174 , A61M60/178 , A61M60/216 , A61M60/226 , A61M60/414 , A61M60/419 , A61M60/422 , A61M60/523 , A61M60/531 , A61M60/538 , A61M60/546 , A61M60/808 , A61M60/816 , A61M60/818 , A61M60/825 , A61M60/857 , A61M60/865 , A61B2562/0223 , A61M60/804 , A61M60/829 , A61M2205/3327 , A61M2207/00
Abstract: Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends of the structure, the first and second bushings being connected to one another by at least one elongate element. The elongate element is caused to radially expand and form at least one helical elongate element, at least partially by axially compressing the structure. The helical elongate element is coated with a coupling agent configured to enhance bonding between the helical elongate element and an elastomeric layer. The coated helical elongate element is coated with the elastomeric layer. Subsequently, an elastomeric film is coupled to the helical elongate element, such that the helical elongate element with the elastomeric film coupled thereto defines a blade of the impeller. Other applications are also described.
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公开(公告)号:US12090314B2
公开(公告)日:2024-09-17
申请号:US17574701
申请日:2022-01-13
Applicant: Magenta Medical Ltd.
Inventor: Yosi Tuval , Daniel Glozman , Gad Lubinsky
IPC: A61M1/00 , A61M60/139 , A61M60/148 , A61M60/17 , A61M60/237 , A61M60/414 , A61M60/806 , A61M60/825
CPC classification number: A61M60/414 , A61M60/139 , A61M60/148 , A61M60/17 , A61M60/237 , A61M60/806 , A61M60/825 , A61M2205/3334 , A61M2230/30
Abstract: Apparatus and methods are described including a tube configured to traverse an aortic valve of a subject. A frame is disposed within at least a portion of the tube. An impeller rotates such as to pump blood from the subject's left ventricle to the subject's aorta. The impeller is disposed inside the tube such that, when the impeller and the tube are deployed inside the subject, and prior to rotation of the impeller, a gap between an outer edge of the impeller and an inner surface of the tube is less than 1 mm. A rigid stabilizing element stabilizes the impeller with respect to the tube, such that during rotation of the impeller, a gap between the outer edge of the impeller and the inner surface of the tube is maintained. Other applications are also described.
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