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公开(公告)号：US20210389338A1
公开(公告)日：2021-12-16
申请号：US17412688
申请日：2021-08-26
Applicant: Meso Scale Technologies, LLC.
Inventor： Manish KOCHAR , Peter J. BOSCO , Ian D. CHAMBERLIN , Bandele JEFFREY-COKER , Eric M. JONES , Gary I. KRIVOY , Aaron H. LEIMKUEHLER , Pei-Ming WU , Kim-Xuan NGUYEN , Pankaj OBEROI , Louis W. PANG , Jennifer PARKER , Victor PELLICIER , Nicholas SAMMONS , George SIGAL , Jacob N. WOHLSTADTER , Michael L. VOCK , Stanley T. SMITH , Carl C. STEVENS , Rodger D. OSBORNE , Kenneth E. PAGE , Michael T. WADE , Jon WILLOUGHBY , Lei WANG , Don E. KRUEGER
IPC: G01N35/00 , B01L3/00 , B01L9/00 , G16H40/67 , G16H10/40 , G16H40/40 , F24F11/30 , G06K7/14 , G06Q10/08 , G06Q10/10
Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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公开(公告)号：US20210025896A1
公开(公告)日：2021-01-28
申请号：US17061095
申请日：2020-10-01
Applicant: Meso Scale Technologies, LLC
Inventor： Charles M. CLINTON , Eli N. Glezer , Bandele JEFFREY-COKER , Sandor L. KOVACS , Sudeep M. KUMAR , George SIGAL , Carl STEVENS , Michael Vock
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20250102511A1
公开(公告)日：2025-03-27
申请号：US18971325
申请日：2024-12-06
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Alexander K. TUCKER-SCHWARTZ , George SIGAL
Abstract: The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).
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公开(公告)号：US20240409983A1
公开(公告)日：2024-12-12
申请号：US18734455
申请日：2024-06-05
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： David ROUTENBERG , Evan GIZZIE , Alexander K. TUCKER-SCHWARTZ , George SIGAL , Khondaker RAHMAN , Deepak NANJAPPA
IPC: C12Q1/6823 , C12Q1/6806 , C12Q1/6834 , C12Q1/6851
Abstract: Provided herein are methods for analyzing a sample for an analyte using proximity-based extension, such as proximity extension strand displacement. Also provided are multiplexed methods for analyzing a sample using proximity-based extension. Provided herein are methods for screening for pairwise combination of binding moieties, for use in a sandwich-type assay. Also provided are compositions that find use in the present methods.
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公开(公告)号：US20240293822A1
公开(公告)日：2024-09-05
申请号：US18436879
申请日：2024-02-08
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Eli N. GLEZER , Stephen HIGGINS , Sandor KOVACS , Sudeep KUMAR , Kenneth PAGE , Kristian ROTH , George SIGAL
CPC classification number: B01L7/525 , B01L3/5027 , B01L2200/027 , B01L2200/0605 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/146 , B01L2200/16 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , C12Q1/686
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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Patent Agency Ranking
公开(公告)号：US20240280786A1
公开(公告)日：2024-08-22
申请号：US18596909
申请日：2024-03-06
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Ian D. CHAMBERLIN , Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Manish KOCHAR , Sandor KOVACS , D.T. LE , Aaron LEIMKUEHLER , George SIGAL , Leo TABAKIN , Jon WILLOUGHBY
CPC classification number: G02B7/36 , G01N21/253 , G01N21/6452 , G01N35/028
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US20240103002A1
公开(公告)日：2024-03-28
申请号：US18473064
申请日：2023-09-22
Applicant: Meso Scale Technologies, LLC.
Inventor： George SIGAL , Leonid DZANTIEV , Priscilla KRAI , Teri-Tu B. NGO
IPC: G01N33/569
CPC classification number: G01N33/56983 , G01N2333/065 , G01N2333/07 , G01N2469/20
Abstract: The invention relates to methods and kits for detecting one or more antibody biomarkers in a sample, wherein the antibody biomarker specifically binds a viral antigen. In embodiments, the viral antigen is a monkeypox virus (MPXV) antigen, a vaccinia virus (VACV) antigen, or combination thereof.
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公开(公告)号：US20230073180A1
公开(公告)日：2023-03-09
申请号：US17930196
申请日：2022-09-07
Applicant: Meso Scale Technologies, LLC.
Inventor： John H. KENTEN , George SIGAL
IPC: G01N1/18
Abstract: A sample collection device having a sample container, a solid phase binding material, and a container sealing component is presented. The sample container may have a housing that forms an opening for receiving a sample, and that encloses a space for holding the sample. The solid phase binding material may be disposed within the space enclosed by the housing of the sample container and may be adapted, when the sample contains an analyte, to bind specifically to the analyte. The container sealing component may be removably attachable to the sample container at the opening thereof, and may be adapted, when attached to the sample container, to form a seal around the opening of the sample container.
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公开(公告)号：US20220365106A1
公开(公告)日：2022-11-17
申请号：US17679663
申请日：2022-02-24
Applicant: Meso Scale Technologies, LLC.
Inventor： Manish KOCHAR , Peter J. BOSCO , Ian D. CHAMBERLIN , Bandele JEFFREY-COKER , Eric M. JONES , Gary I. KRIVOY , Don E. KRUEGER , Aaron H. LEIMKUEHLER , Pei-Ming WU , Kim-Xuan NGUYEN , Pankaj OBEROI , Louis W. PANG , Jennifer PARKER , Victor PELLICIER , Nicholas SAMMONS , George SIGAL , Jacob N. WOHLSTADTER , Michael L. VOCK , Stanley T. SMITH , Carl C. STEVENS , Rodger D. OSBORNE , Kenneth E. PAGE , Michael T. WADE , Jon WILLOUGHBY , Lei WANG
IPC: G01N35/00 , B01L3/00 , B01L9/00 , G16H40/67 , G16H10/40 , G16H40/40 , F24F11/30 , G06K7/14 , G06Q10/08 , G06Q10/10
Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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公开(公告)号：US20220019053A1
公开(公告)日：2022-01-20
申请号：US17492187
申请日：2021-10-01
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian CHAMBERLIN , Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Manish KOCHAR , Sandor KOVACS , D.T. Le , Aaron LEIMKUEHLER , George SIGAL , Leo TABAKIN , Jon WILLOUGHBY
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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