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    Ion Concentration Polarization-Electrocoagulation Hybrid Water Treatment System
    13.
    发明申请
    Ion Concentration Polarization-Electrocoagulation Hybrid Water Treatment System 有权
    离子浓度极化 - 电凝混合水处理系统

    公开(公告)号：US20170066665A1

    公开(公告)日：2017-03-09

    申请号：US14857133

    申请日：2015-09-17

    申请人： Massachusetts Institute of Technology

    发明人： Siwon Choi ,  Jongyoon Han

    IPC分类号： C02F1/463 ,  C02F1/46

    CPC分类号： C02F1/463 ,  B01D61/42 ,  B01D2311/2642 ,  C02F1/4604 ,  C02F1/469 ,  C02F2103/08 ,  C02F2201/46115

    摘要： Between two juxtaposed similar ion exchange membranes (AEMs or CEMs), an ion depletion zone and ion enrichment zone are generated under an electric field. As cations are selectively transferred through the CEMs, for example, anions are relocated in order to achieve electro-neutrality, resulting in the concentration drop (increase) in ion depletion (enrichment) zone. The use of a sacrificial metal anode allows electrocoagulation (EC) concurrently with ICP thereby permitting concentration of both ionic and non-ionic impurities to occur at the same time within the same cell or device.

    摘要翻译： 在两个并置的类似离子交换膜（AEM或CEM）之间，在电场下产生离子耗尽区和离子富集区。 当阳离子选择性地通过CEM转移时，例如，阴离子被重新定位以实现电中性，导致离子耗尽（富集）区域的浓度下降（增加）。 牺牲金属阳极的使用允许与ICP同时电凝（EC），从而允许离子和非离子杂质的浓度同时在相同的电池或器件内发生。

    METHOD OF PROFILING A SAMPLE COMPRISING A PLURALITY OF CELLS AND A SYSTEM FOR PERFORMING THE SAME
    16.
    发明申请
    METHOD OF PROFILING A SAMPLE COMPRISING A PLURALITY OF CELLS AND A SYSTEM FOR PERFORMING THE SAME 有权

    公开(公告)号：US20230039455A1

    公开(公告)日：2023-02-09

    申请号：US17758531

    申请日：2021-01-08

    申请人： Massachusetts Institute of Technology ,  National University Hospital (Singapore) Pte. Ltd.

    发明人： Jongyoon Han ,  Kerwin Zeming Kwek ,  Win Sen Kuan

    IPC分类号： B01L3/00

    摘要： The invention is to provide a method of profiling a sample comprising a plurality of cells, the method comprising: flowing cells from the sample through a first array of pillars to obtain one or more distribution profiles of cells sorted by the first array; flowing cells from the sample through a second array of pillars that is different from the first array of pillars to obtain on one or more distribution profiles of cells sorted by the second array; and deriving a biophysical signature of the sample based on at least the one or more distribution profiles of the cells sorted by the first array and/or the one or more distribution profiles of the cells sorted by the second array. The method further comprises determining a health status of a subject based on the biophysical signature of the sample. The invention is also to provide a sample profiling system. In various embodiments, the distribution profile of cells in the output regions is indicative of one or more biophysical properties of the cells, which may include the size and deformability of the cells. The pillars in the first array and the second array may have a shape selected from the group consisting of a substantially L shape and a substantially inverse L shape, mirror reflections thereof or combinations thereof.