公开(公告)号：US11464977B2

公开(公告)日：2022-10-11

申请号：US17194943

申请日：2021-03-08

Applicant: Medtronic, Inc.

Inventor： Randal C. Schulhauser ,  Avram Scheiner ,  Linnea R. Lentz

IPC: A61N1/36 ,  A61B5/318 ,  A61B5/053 ,  A61N1/05 ,  A61B5/00 ,  A61B5/08

Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.

公开(公告)号：US20200072782A1

公开(公告)日：2020-03-05

申请号：US16116306

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: G01N27/327

Abstract: An electrochemical sensor may include a common reference electrode, at least one counter electrode, and a work electrode platform including a plurality of respective work electrodes. Each respective work electrode of the plurality of respective work electrodes may be electrically coupled to the common reference electrode and include a respective reagent substrate configured to react with a respective analyte to produce a signal indicative of a concentration of the respective analyte.

公开(公告)号：US20230293023A1

公开(公告)日：2023-09-21

申请号：US18163173

申请日：2023-02-01

Applicant: Medtronic, Inc.

Inventor： Elise J. Higgins ,  Yong K. Cho ,  Richard J. O’Brien ,  Randal C. Schulhauser

IPC: A61B5/0205 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/389 ,  A61B5/145 ,  A61B5/344 ,  A61B5/28 ,  A61B5/296 ,  A61B5/1464

CPC classification number: A61B5/02055 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/1464 ,  A61B5/28 ,  A61B5/296 ,  A61B5/344 ,  A61B5/389 ,  A61B5/4356 ,  A61B5/4362 ,  A61B5/7475 ,  A61B5/0245

Abstract: A system for sensing physiological traits of a maternal patient and a fetal patient carried by the maternal patient during a pregnancy using one or more sensors. The system may use the physiological traits sensed to define a maternal attribute for the maternal patient and a fetal attribute for the fetal patient, such as a heart rate, blood pressure, respiration rate, temperature, oxygen saturation level, or other attributes. The system is configured to compare the maternal attribute to a maternal limit describing a threshold for the maternal patient and/or compare the fetal attribute to a fetal limit describing a threshold for the fetal patient. The system is configured to issue a communication to the maternal patient and/or a clinician based on the comparisons. In examples, the system regularly communicates the maternal attribute and/or the fetal attribute to an output device of the maternal patient and/or a clinician.

公开(公告)号：US20230157762A1

公开(公告)日：2023-05-25

申请号：US17955941

申请日：2022-09-29

Applicant: Medtronic, Inc.

Inventor： Peter N. Braido ,  Randal C. Schulhauser ,  Niall F. Duffy ,  Julie A. Benton ,  Zhongping Yang ,  Richard J. O'Brien ,  Walton W. Baxter ,  Roy A. Wilsker ,  Tal Davidson ,  William C. Harding ,  Max L. Balter ,  Joseph D. Brannan ,  Mark L. Stiger ,  Keith D. Perkins

IPC: A61B34/20 ,  A61B34/37 ,  A61B90/00

CPC classification number: A61B34/20 ,  A61B34/37 ,  A61B90/37 ,  A61B2017/00207

Abstract: Disclosed herein are techniques for implementing an intelligent assistance (“IA”) or extended intelligence (“EI”) ecosystem for soft tissue luminal applications. In various embodiments, a computing system analyzes first layer input data (indicating movement, position, and/or relative distance for a person(s) and object(s) in a room) and second layer input data. The second layer input data includes sensor and/or imaging data of a patient. Based on the analysis, the computing system generates one or more recommendations for guiding a medical professional in navigating a surgical device(s) with respect to one or more soft tissue luminal portions of the patient. The recommendation(s) include at least one mapped guide toward, in, and/or around the one or more soft tissue luminal portions. The mapped guide can include data corresponding to at least three dimensions, e.g., a 3D image/video. The computing system can present the recommendation(s) as image-based output, using a user experience device.

公开(公告)号：US11623089B2

公开(公告)日：2023-04-11

申请号：US17930645

申请日：2022-09-08

Applicant: Medtronic, Inc.

Inventor： Randal C. Schulhauser ,  Avram Scheiner ,  Linnea R. Lentz

IPC: A61N1/36 ,  A61B5/318 ,  A61B5/053 ,  A61N1/05 ,  A61B5/00 ,  A61B5/08

Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.

公开(公告)号：US20220369961A1

公开(公告)日：2022-11-24

申请号：US17663657

申请日：2022-05-16

Applicant: Medtronic, Inc.

Inventor： Kamal Deep Mothilal ,  Michael D. Eggen ,  Ning Yu ,  John P. Keane ,  Shantanu Sarkar ,  Randal C. Schulhauser ,  David L. Probst ,  Mark R. Boone ,  Kenneth A. Timmerman ,  Stanley J. Taraszewski ,  Matthew A. Joyce ,  Amruta Paritosh Dixit ,  Kathryn E. Hilpisch ,  Kathryn Ann Milbrandt ,  Laura M. Zimmerman ,  Matthew L. Plante

IPC: A61B5/145 ,  A61B5/0205 ,  A61B5/00 ,  G16H50/20 ,  G16H50/30

Abstract: This disclosure is directed to systems and techniques for detecting change in patient health based upon patient data. In one example, a medical system comprising processing circuitry communicably coupled to a glucose sensor and configured to generate continuous glucose sensor measurements of a patient. The processing circuitry is further configured to: extract at least one feature from the continuous glucose sensor measurements over at least one time period, wherein the at least one feature comprises one or more of an amount of time within a pre-determined glucose level range, a number of hypoglycemia events, a number of hyperglycemia events, or one or more statistical metrics corresponding to the continuous glucose sensor measurements; apply a machine learning model to the at least one extracted feature to produce data indicative of a risk of a cardiovascular event; and generate output data based on the risk of the cardiovascular event.

公开(公告)号：US20220133999A1

公开(公告)日：2022-05-05

申请号：US17085963

申请日：2020-10-30

Applicant: Medtronic, Inc.

Inventor： Jason C. Lee ,  Hyun J. Yoon ,  Jon E. Thissen ,  Ashley L. Galarneau ,  Randal C. Schulhauser

IPC: A61M5/172 ,  G16H40/63 ,  G06N20/00

Abstract: A system for monitoring a patient includes one or more processors and a sensor device implemented in circuitry. The system is configured to measure, using the sensor device, an impedance of tissue of the patient and determine, using one or more processors, a physiological parameter comprising at least one of a heart rate, cardiac output, vascular tone, perfusion level, fluid status, respiration effort, or respiration rate of the patient based on the impedance of the tissue of the patient. The system is configured to facilitate therapy, using the one or more processors, based on the determined physiological parameter.

公开(公告)号：US10852268B2

公开(公告)日：2020-12-01

申请号：US16116306

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: G01N27/327 ,  G01N33/483

Abstract: An electrochemical sensor may include a common reference electrode, at least one counter electrode, and a work electrode platform including a plurality of respective work electrodes. Each respective work electrode of the plurality of respective work electrodes may be electrically coupled to the common reference electrode and include a respective reagent substrate configured to react with a respective analyte to produce a signal indicative of a concentration of the respective analyte.

公开(公告)号：US20200069226A1

公开(公告)日：2020-03-05

申请号：US16116346

申请日：2018-08-29

Applicant: Medtronic, Inc.

Inventor： Daniel Hahn ,  Mohsen Askarinya ,  James K. Carney ,  Patrick W. Kinzie ,  Jennifer Lorenz Marckmann ,  Randal C. Schulhauser ,  Santhisagar Vaddiraju ,  Akhil Srinivasan ,  David Probst ,  Alejo Chavez Gaxiola

IPC: A61B5/1468 ,  A61B5/145 ,  A61B5/053

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

公开(公告)号：US09839783B2

公开(公告)日：2017-12-12

申请号：US14340893

申请日：2014-07-25

Applicant: Medtronic, Inc.

Inventor： Randal C. Schulhauser ,  Ralph B. Danzl ,  Sharon Kohanna Murray ,  Michael F. Mattes

IPC: A61N1/37 ,  A61N1/39 ,  A61N1/36 ,  G01R33/028 ,  A61B5/055 ,  C23C14/34 ,  G01D5/242 ,  G01L1/16 ,  G01L1/18 ,  G01R33/00

CPC classification number: A61N1/3718 ,  A61B5/055 ,  A61N1/36128 ,  A61N1/37 ,  A61N1/3925 ,  C23C14/34 ,  G01D5/242 ,  G01L1/16 ,  G01L1/18 ,  G01R33/0052 ,  G01R33/0283 ,  G01R33/0286

Abstract: Magnetic field detectors include a proof mass suspended by deformable arms similar to a three dimensional accelerometer. The magnetic field detectors further include magnetically sensitive material present on the proof mass and/or deformable arms to cause movement of the proof mass and/or deformable arms when in the presence of a magnetic field. This movement is converted to an electrical signal and that electrical signal is compared to a reference to determine if a magnetic field of interest is present. The magnetic field detector may be included within an implantable medical device, and when the magnetic field detector indicates that a magnetic field of an MRI scanner is present, the implantable medical device may switch to an MRI mode of operation. The device may also switch back to a normal mode of operation once the MRI scanner is no longer detected such as after a predefined amount of time.