公开(公告)号：US6045254A

公开(公告)日：2000-04-04

申请号：US996411

申请日：1997-12-22

Applicant: Michael Inbar ,  Sharon Igal

Inventor： Michael Inbar ,  Sharon Igal

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/20 ,  A61J9/00 ,  B65D20060101 ,  B65D25/08 ,  B65D51/28 ,  B65D81/32 ,  B01F11/00

CPC classification number: A61J11/04 ,  A61J9/00 ,  B65D25/087 ,  B65D51/2864 ,  B65D81/3255 ,  A61J1/2031 ,  A61J1/2093 ,  A61J11/008 ,  Y10S215/08

Abstract: A container for storing two components separately and then mixing them prior to use includes a housing having an opening and a neck portion, a displaceable member, and a closure member. The housing is formed with a first compartment and a second compartment intercommunicating at the neck portion. The displaceable member has a partition wall for sealing the neck portion. The displaceable member is formed such that the partition wall moves from a non-sealing position in which the first and second compartments intercommunicate to a sealing position in which the neck portion is sealed. The displaceable member also may feature at least one conduit for allowing introduction of a component through the opening into the housing. The closure member seals the at least one conduit of the displaceable member and/or the opening of the housing. The displaceable member may be moved by rotating, pushing or pulling and may be moveable by a portion exterior to the housing. The seal formed by the partition wall of the displaceable member may be reformable, i.e., capable of being resealed. A pre-packaged, single use, two compartment container according to some embodiments of the invention have an unremovable closure member, an unreformable seal, an unfastenable closure member after it has been removed or is constructed in a manner or of materials which allow only a single use. The two-compartment container may also include a dosing assembly for dispensing a predetermined quantity of mixed formulation.

Abstract translation: 用于分开存储两个部件，然后在使用之前混合的容器包括具有开口和颈部的壳体，可移位部件和封闭部件。 壳体形成有第一隔室和在颈部处相互连通的第二隔室。 可移位构件具有用于密封颈部的分隔壁。 可移动构件被形成为使得分隔壁从其中第一和第二隔室相互连通的非密封位置移动到颈部被密封的密封位置。 可移动构件还可以具有至少一个导管，用于允许通过开口将部件引入壳体。 封闭构件密封可移动构件的至少一个导管和/或壳体的开口。 可移动构件可以通过旋转，推动或拉动而移动，并且可以通过壳体外部的部分移动。 由可移动构件的分隔壁形成的密封件可以是可重新形成的，即可以被再密封。 根据本发明的一些实施例的预先封装的，单次使用的两个隔间容器具有不可移除的封闭构件，不可变形的密封件，在其被移除之后的不可松开的封闭构件或者以仅允许 单次使用 双室容器还可以包括用于分配预定量的混合制剂的计量组合件。

公开(公告)号：US5838510A

公开(公告)日：1998-11-17

申请号：US739877

申请日：1996-10-31

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: G11B5/012 ,  G11B20/18 ,  G11B27/34 ,  G11B27/36 ,  G11B33/10 ,  G11B5/027

CPC classification number: G11B5/012 ,  G11B20/1816 ,  G11B27/34 ,  G11B27/36 ,  G11B33/10

Abstract: The present invention relates to a method and apparatus for the measurement of defects in magnetic recording disks using a logarithmic amplifier. A magnetic head senses a magnetic field of a magnetic disk and creates a read signal having a varying amplitude. The test apparatus has a squarer which receives and squares the read signal. A logarithmic amplifier coupled to the squarer converts the squared signal to a logarithmic signal. The logarithmic signal is filtered by a first filter. A second filter coupled to the logarithmic amplifier provides an average of the peaks of the logarithmic signal. A digital-to-analog converter coupled to the second filter scales the output of the second filter. The test apparatus further comprises a comparator having a first input and a second input, where the first input is coupled to the first filter, and the second input is coupled to the digital-to-analog converter. The comparator provides an output signal in response to receiving a signal from the first filter having an amplitude that is lower than an average of a predetermined number of peak values of the signal, thereby indicating an error in the disk. In another embodiment, the test apparatus is implemented using a rectifier instead of a squarer.

Abstract translation: 本发明涉及使用对数放大器测量磁记录盘中的缺陷的方法和装置。 磁头感测磁盘的磁场并产生具有变化幅度的读取信号。 测试装置具有接收和平移读取信号的平方器。 耦合到平方的对数放大器将平方信号转换成对数信号。 对数信号由第一滤波器滤波。 耦合到对数放大器的第二滤波器提供对数信号的峰值的平均值。 耦合到第二滤波器的数模转换器缩放第二滤波器的输出。 测试装置还包括具有第一输入和第二输入的比较器，其中第一输入耦合到第一滤波器，并且第二输入耦合到数 - 模转换器。 比较器响应于从第一滤波器接收的信号具有低于信号的预定峰值值的平均值的幅度，从而指示盘中的错误，提供输出信号。 在另一个实施例中，使用整流器而不是平方器来实现测试装置。

公开(公告)号：US5314074A

公开(公告)日：1994-05-24

申请号：US971525

申请日：1992-11-03

Applicant: Michael Inbar ,  Gerald Slutzky ,  Mordechai Radushetzky ,  David Shitrit

Inventor： Michael Inbar ,  Gerald Slutzky ,  Mordechai Radushetzky ,  David Shitrit

IPC: B04B5/02 ,  G01N1/10 ,  G01N33/48 ,  G01N33/49 ,  B03D1/00

CPC classification number: G01N33/491

Abstract: In the performance of density gradient centrifugation back mixing after centrifugation is prevented by placing a snugly fitted layering insert within the vessel. The insert is capable of supporting the body of liquid dispersion to be centrifuged under regular gravity condition and enables bi-directional cross-flow during centrifugation. A small mesh filter plate may be placed on top of the layering insert.

Abstract translation: 在密度梯度离心的性能中，通过将紧密配合的层叠插入物放置在容器内来防止离心后的离心回流混合。 该插入件能够支持液体分散体在常规重力条件下离心，并在离心过程中实现双向交叉流动。 可以将小网状过滤板放置在分层插入件的顶部。

公开(公告)号：US4651105A

公开(公告)日：1987-03-17

申请号：US794308

申请日：1985-11-01

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: G01R19/04 ,  G11B20/18 ,  H03K5/153

CPC classification number: G01R19/04 ,  G11B20/1816

Abstract: A digital peak detecting circuit for receiving a pulse train of electrical signals having a frequency within a known frequency range and for converting the same into digital signals is shown. The digital peak detecting circuit includes an input circuit having a phase-locked loop for producing clock pulses at a frequency which is a preselected integer of the electrical signals frequency and for deriving therefrom an analog input signal. A pulse control circuit receives and counts a predetermined number of clock pulses and produces count enabling signals. A peak detecting circuit is provided which includes a comparator which has the analog input signal and a analog output signal voltage applied to the inputs thereof and which has an output coupled to the pulse control circuit. A digital counting circuit is responsive to count enabling signals by changing count direction and produces discrete digital output signals which are stored in a latch register at the time the digital counting circuit changes its count direction. A digital-to-analog converter produces the analog output signal voltage and it is applied to the comparator input for comparing the analog input signal with the analog output signal voltage and the comparator enables the digital counting circuit as long as the analog input signal is of a greater magnitude than the analog output signal voltage, and when this condition is reversed, the digital counting circuit is reversed in counting direction, and the binary value thereof is stored in the latch register.

Abstract translation: 一种数字峰值检测电路，用于接收具有在已知频率范围内的频率的电信号的脉冲序列并将其转换为数字信号。 数字峰值检测电路包括具有锁相环的输入电路，用于产生频率为电信号频率的预选整数的时钟脉冲，并从其中得到模拟输入信号。 脉冲控制电路接收并计数预定数量的时钟脉冲并产生计数使能信号。 提供了一种峰值检测电路，其包括具有模拟输入信号和施加到其输入的模拟输出信号电压的比较器，其具有耦合到脉冲控制电路的输出。 数字计数电路响应于通过改变计数方向对使能信号进行计数，并产生在数字计数电路改变其计数方向时存储在锁存寄存器中的离散数字输出信号。 数模转换器产生模拟输出信号电压，并将其应用于比较器输入，用于将模拟输入信号与模拟输出信号电压进行比较，只要模拟输入信号为 比模拟输出信号电压大一个数量级，当该条件反转时，数字计数电路在计数方向上反转，其二进制值存储在锁存寄存器中。

公开(公告)号：US4574234A

公开(公告)日：1986-03-04

申请号：US654809

申请日：1984-09-26

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: G01R19/04 ,  G11B20/18 ,  G01R15/12 ,  G01R23/12

CPC classification number: G11B20/1816 ,  G01R19/04

Abstract: An electrical measuring system for measuring selected parameters of electrical signals derived from magnetic recording and having a frequency within a known frequency range wherein the system includes an input stage having an automatic amplifier for selectively amplifying the electrical signals to a preselected amplitude level, a first circuit which includes a digital peak detecting circuit for producing digital signals representing peak amplitude and the amplitude of the electrical signals sampled at closely spaced intervals and wherein the digital peak detecting circuit includes circuitry for sampling the preselected amplitude level electrical signals at a frequency which is less than the frequency of the electrical signals, a second circuit which includes a first phase-locked loop circuit, a frequency dividing circuit and a second phase-locked loop circuit for producing an output signal representing the frequency of a remnant signal in the electrical signals which is applied to the digital peak detecting circuit for producing a digital signal representing the remnant signal magnitude, a third and fourth stage for producing direct current voltage signals representing the power magnitude of noise spectra and the DC content of a pulse train for deriving from the pulse widths of the electrical signals, respectively, and for applying the same to the digital peak detecting circuit to produce a digital representation thereof is shown. A method for processing electrical signals to produce digital representations of the amplitude, read-over-write ratio, signal-to-noise ratio and the average pulse widths thereof is shown.

Abstract translation: 一种电测量系统，用于测量从磁记录导出的电信号的选定参数，并且具有在已知频率范围内的频率，其中系统包括具有用于选择性地将电信号放大到预选幅度电平的自动放大器的输入级，第一电路 其包括数字峰值检测电路，用于产生表示峰值振幅的数字信号和以近间隔采样的电信号的振幅，并且其中数字峰值检测电路包括用于以小于等于的频率对预选的幅度电平电信号进行采样的电路 电信号的频率，第二电路，其包括第一锁相环电路，分频电路和第二锁相环电路，用于产生表示电信号中剩余信号频率的输出信号， 适用于 数字峰值检测电路，用于产生表示剩余信号幅度的数字信号;第三和第四级，用于产生表示噪声频谱的功率幅度的直流电压信号和用于从电气的脉冲宽度导出的脉冲串的DC内容 信号，并将其应用于数字峰值检测电路以产生其数字表示。 示出了用于处理电信号以产生幅度，读写比，信噪比及其平均脉冲宽度的数字表示的方法。

公开(公告)号：US3971952A

公开(公告)日：1976-07-27

申请号：US505530

申请日：1974-09-12

Applicant: Michael Inbar ,  Meir Shinitzky

Inventor： Michael Inbar ,  Meir Shinitzky

IPC: A61D13/00 ,  G01N21/64 ,  G01N21/38

CPC classification number: G01N21/6445

Abstract: Abnormal behavior of mammalian cells is detected in vitro by measuring the fluidity or an associated phenomenon of the lipid layer of the cell surface membrane. Abnormal behavior of cells, in particular if caused by malignant transformations, is associated with increase of fluidity of the liquid layer of the cell membrane, as compared with normal cells. The fluidity can be determined, e.g., by measuring the degree of fluorescence polarization of the radiation emitted from a suspension of cells labelled in the lipid layer with a fluorescent compound. 1,6-Diphenyl-1,3,5-hexatriene was found to be a suitable fluorescent probe.

Abstract translation: 通过测量细胞表面膜的脂质层的流动性或相关现象，在体外检测哺乳动物细胞的异常行为。 与正常细胞相比，特别是恶性转化引起的细胞的异常行为与细胞膜的液体层的流动性的增加相关。 流动性可以例如通过测量由荧光化合物在脂质层中标记的细胞的悬浮液发射的辐射的荧光偏振度来确定。 发现1,6-二苯基-1,3,5-己三烯是合适的荧光探针。

公开(公告)号：US08920318B2

公开(公告)日：2014-12-30

申请号：US11995107

申请日：2006-06-12

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: A61B5/00 ,  G06Q10/00 ,  G06F19/00 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/087

CPC classification number: A61B5/7275 ,  A61B5/0008 ,  A61B5/02055 ,  A61B5/024 ,  A61B5/02411 ,  A61B5/0464 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/083 ,  A61B5/087 ,  A61B5/14542 ,  A61B5/412 ,  G06F19/00 ,  G16H50/70

Abstract: Methods, systems and computer-readable code for generating a forecast of a life-threatening condition, for example sepsis, in a subject, for example an infant, are disclosed. According to some embodiments, the forecast is generated in accordance with measurement values for a plurality of different vital sign parameters. In exemplary embodiments, vital sign parameters from a plurality of physiological systems are used to generate the forecast of the life-threatening condition. In exemplary embodiments, at least one vital sign parameter is other than a cardiac parameter. Non-limiting exemplary vital sign parameters may include one or more of a heart rate parameter, a respiration rate parameter, a bradycardia parameter, a desaturation parameter, a temperature parameter (for example, body temperature) and a body mass parameter.

Abstract translation: 公开了用于在受试者例如婴儿中产生危及生命的状况（例如败血症）的预测的方法，系统和计算机可读代码。 根据一些实施例，根据多个不同生命体征参数的测量值来生成预测。 在示例性实施例中，使用来自多个生理系统的生命体征参数来产生对生命危险状况的预测。 在示例性实施例中，至少一个生命体征参数不同于心脏参数。 非限制性示例性生命体征参数可以包括心率参数，呼吸速率参数，心动过缓参数，去饱和参数，温度参数（例如体温）和身体质量参数中的一个或多个。

公开(公告)号：US20090163776A1

公开(公告)日：2009-06-25

申请号：US11995107

申请日：2006-06-12

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: A61B5/00

CPC classification number: A61B5/7275 ,  A61B5/0008 ,  A61B5/02055 ,  A61B5/024 ,  A61B5/02411 ,  A61B5/0464 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/083 ,  A61B5/087 ,  A61B5/14542 ,  A61B5/412 ,  G06F19/00 ,  G16H50/70

Abstract: Methods, systems and computer-readable code for generating a forecast of a life-threatening condition, for example sepsis, in a subject, for example an infant, are disclosed. According to some embodiments, the forecast is generated in accordance with measurement values for a plurality of different vital sign parameters. In exemplary embodiments, vital sign parameters from a plurality of physiological systems are used to generate the forecast of the life-threatening condition. In exemplary embodiments, at least one vital sign parameter is other than a cardiac parameter. Non-limiting exemplary vital sign parameters may include one or more of a heart rate parameter, a respiration rate parameter, a bradycardia parameter, a desaturation parameter, a temperature parameter (for example, body temperature) and a body mass parameter.

Abstract translation: 公开了用于在受试者例如婴儿中产生危及生命的状况（例如败血症）的预测的方法，系统和计算机可读代码。 根据一些实施例，根据多个不同生命体征参数的测量值来生成预测。 在示例性实施例中，使用来自多个生理系统的生命体征参数来产生对生命危险状况的预测。 在示例性实施例中，至少一个生命体征参数不同于心脏参数。 非限制性示例性生命体征参数可以包括心率参数，呼吸速率参数，心动过缓参数，去饱和参数，温度参数（例如体温）和身体质量参数中的一个或多个。

公开(公告)号：US20050125038A1

公开(公告)日：2005-06-09

申请号：US10499031

申请日：2002-12-16

Applicant: Michael Inbar ,  Moshe Olshevski

Inventor： Michael Inbar ,  Moshe Olshevski

IPC: A61J7/00 ,  A61J9/00 ,  A61J11/00 ,  A61J17/00

CPC classification number: A61J11/008 ,  A61J7/0046 ,  A61J7/0053 ,  A61J9/005 ,  A61J11/0085 ,  A61J17/001 ,  A61J17/006

Abstract: A single-dosage liquid medication dispensing unit, especially useful for newborns, babies, and young children, comprising a flexible container containing said liquid medication therein and having a nipple-shaped portion with an orifice for allowing sucking by a newborn, baby, or young child, wherein said orifice is initially in an inactive state and is adapted for being activated by a user just prior to being given to a newborn, baby, or young child for sucking. A method for delivering a single-dosage of a liquid medication is also disclosed.

Abstract translation: 一种单剂量液体药物分配单元，特别适用于新生儿，婴儿和幼儿，包括容纳所述液体药物的柔性容器，并具有带有孔口的乳头状部分，用于允许新生儿，婴儿或年轻人吸吮 小孩，其中所述孔口最初处于非活动状态，并且适于在给予新生儿，婴儿或幼儿进行吸吮之前由使用者激活。 还公开了用于递送单次剂量的液体药物的方法。

公开(公告)号：US5838153A

公开(公告)日：1998-11-17

申请号：US766901

申请日：1996-12-13

Applicant: Michael Inbar

Inventor： Michael Inbar

IPC: G01R33/12 ,  G11B5/012 ,  G11B20/10 ,  G11B27/36 ,  G11B33/10 ,  G01N27/72 ,  G11B5/09

CPC classification number: G11B20/10203 ,  G01R33/1207 ,  G11B27/36 ,  G11B5/012 ,  G11B33/10

Abstract: A disk certifier which analyzes a read signal generated from a disk of a hard disk drive. The read signal typically has a sinusoidal waveform with modulated peak amplitudes. The waveform is generally defined by the equation A.multidot.sin(wt).multidot.(1-m(t)), where the term m(t) is the amplitude modulation of the signal. The peak signal is provided to a phase lock loop circuit which generates a multiplier peak signal generally of the form sin(wt). The certifier includes a multiplier which multiplies the read signal by the multiplier read signal to provide a multiplied read signal described by the equation A/2.multidot.(1-cos 2(wt)).multidot.(1-m(t)). The multiplied read signal is filtered by a low pass filter which has a cut-off frequency Wc below w. The low pass filter provides a filtered multiplied read signal which is described by the equation A.multidot.(1-g(t)), wherein the term g(t) is the portion of m(t) with frequencies below Wc. The filtered multiplied read signal is then compared to a threshold value(s) to determine a pass/fail error condition of the read signal. The certifier also has a histogram circuit which detects, counts and stores the occurrence of each peak amplitude value of the read signal. The peak amplitude data can be processed to plot a histogram which shows how many times the read signal produced various peak amplitudes. The histogram can be used to determine the actual performance of the disk certifier.

Abstract translation: 磁盘验证器，用于分析从硬盘驱动器的磁盘生成的读取信号。 读信号通常具有调制峰值幅度的正弦波形。 波形通常由等式Axsin（wt）x（1-m（t））定义，其中项m（t）是信号的幅度调制。 峰值信号被提供给锁相环电路，其产生通常为sin（wt）形式的乘法器峰值信号。 验证器包括乘法器，其将读取信号乘以乘法器读取信号，以提供由等式A / 2x（1-cos 2（wt））×（1-m（t））描述的相乘的读取信号。 倍增的读取信号被低通滤波器滤波，低通滤波器的截止频率Wc低于w。 低通滤波器提供由等式Ax（1-g（t））描述的滤波乘法读信号，其中项g（t）是频率低于Wc的m（t）部分。 然后将经滤波的乘法读取信号与阈值（s）进行比较，以确定读取信号的通过/失败错误状况。 验证者还具有检测，计数和存储读取信号的每个峰值振幅值的出现的直方图电路。 可以处理峰值幅度数据来绘制直方图，显示读取信号产生各种峰值幅度的次数。 直方图可用于确定磁盘验证者的实际性能。