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11.发明授权Process for producing semiconductor nanocrystal cores, core-shell, core-buffer-shell, and multiple layer systems in a non-coordinating solvent utilizing in situ surfactant generation 失效使用原位表面活性剂生成的非配位溶剂中制备半导体纳米晶核，核 - 壳，核 - 缓冲壳和多层体系的方法公开(公告)号：US07193098B1
公开(公告)日：2007-03-20
申请号：US10804629
申请日：2004-03-19
摘要： A process for producing semiconductor nanocrystal cores, core-shell, core-buffer-shell, and multiple layer systems is disclosed. The process involves a non-coordinating solvent and in situ surfactant generation.
摘要翻译： 公开了一种制造半导体纳米晶核，核 - 壳，核 - 缓冲壳和多层系统的方法。 该方法涉及非配位溶剂和原位表面活性剂的产生。
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公开(公告)号：US08035016B2
公开(公告)日：2011-10-11
申请号：US12555609
申请日：2009-09-08
申请人： Earl J. Bergey , Adela Bonoiu , Supriya Mahajan , Paras N. Prasad , Indrajit Roy , Stanley A. Schwartz , Ken-Tye Yong
发明人： Earl J. Bergey , Adela Bonoiu , Supriya Mahajan , Paras N. Prasad , Indrajit Roy , Stanley A. Schwartz , Ken-Tye Yong
IPC分类号： A61P43/00 , C12N15/113
CPC分类号： C12N15/111 , A61K9/5115 , C12N15/113 , C12N2310/14 , C12N2320/32 , Y10S977/773
摘要： Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
摘要翻译： 提供了用于抑制一种或多种靶基因表达的方法和组合物。 组合物含有可通过与表面官能化金纳米棒（GNR）静电复合的RNA干扰（RNAi）抑制靶基因表达的RNA多核苷酸。 RNA多核苷酸不共价结合表面官能化的GNRs。 该方法涉及抑制个体中靶基因的表达。 该方法通过向个体施用有效量的含有可以通过RNAi抑制靶基因表达的RNA多核苷酸（例如siRNA）静电复合的表面官能化GNR的组合物来进行。 siRNA不与表面官能化的GNR共价结合。
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13.发明授权High density coupling of quantum dots to carbon nanotube surface for efficient photodetection 失效量子点高密度耦合到碳纳米管表面，以实现有效的光电检测公开(公告)号：US08003979B2
公开(公告)日：2011-08-23
申请号：US11673850
申请日：2007-02-12
CPC分类号： H01L51/0049 , B82Y10/00 , B82Y30/00 , H01L51/0037 , H01L51/0042 , H01L51/426 , H01L2251/308 , Y02E10/549 , Y02P70/521 , Y10S977/745 , Y10S977/847
摘要： The present invention relates to a method of preparing a carbon nanotube-quantum dot conjugate having a high density of quantum dots (QDs) on its surface. This method involves providing a plurality of semiconductor quantum dots and providing a thiol-functionalized carbon nanotube having a plurality of terminal thiol groups on its surface. The plurality of semiconductor quantum dots are attached to the surface of the carbon nanotube under conditions effective to yield a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention also relates to a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention further relates to a photodetector device. This device includes a substrate and a nanocomposite layer. The nanocomposite layer includes a plurality of the carbon nanotube-quantum dot conjugates previously described.
摘要翻译： 本发明涉及一种制备其表面上具有高密度量子点（QD）的碳纳米管 - 量子点共轭体的方法。 该方法包括提供多个半导体量子点，并在其表面上提供具有多个末端巯基的硫醇官能化碳纳米管。 在有效产生其表面上具有高密度的量子点的碳纳米管 - 量子点共轭体的条件下，多个半导体量子点附着在碳纳米管的表面上。 本发明还涉及其表面上具有高密度的量子点的碳纳米管 - 量子点共轭体。 本发明还涉及一种光检测器装置。 该器件包括衬底和纳米复合层。 纳米复合层包括前面描述的多个碳纳米管 - 量子点共轭物。
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公开(公告)号：US06514481B1
公开(公告)日：2003-02-04
申请号：US09718825
申请日：2000-11-22
申请人： Paras N. Prasad , Earl J. Bergey , Charles Liebow , Laurent Levy
发明人： Paras N. Prasad , Earl J. Bergey , Charles Liebow , Laurent Levy
IPC分类号： A61B5055
CPC分类号： B82Y5/00 , A61K47/64 , A61K47/6923 , A61N1/406 , A61N2/00 , Y10T436/24
摘要： The present invention provides novel nanosized particles termed as “nanoclinics” for therapeutic and/or diagnostic use. The particles have a core made of a therapeutic or diagnostic material surrounded by a shell. Further, the particles contain a targeting agent on the surface of the shell for specific recognition of targeted cells. A method is also provided for lysis of cells using DC magnetic field. Further, the present invention also provides a method for fabrication of nanoclinics that can target and lyse specific cells such as cancer cells.
摘要翻译： 本发明提供用于治疗和/或诊断用途的称为“纳米细胞学”的新型纳米尺寸颗粒。 颗粒具有由壳包围的治疗或诊断材料制成的芯。 此外，颗粒在壳的表面上含有靶向剂，用于特异性识别靶细胞。 还提供了使用DC磁场裂解细胞的方法。 此外，本发明还提供了可以靶向和裂解诸如癌细胞的特定细胞的纳米抗生素的制造方法。
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公开(公告)号：US20100125100A1
公开(公告)日：2010-05-20
申请号：US12555609
申请日：2009-09-08
申请人： Earl J. Bergey , Adela Bonoiu , Supriya Mahajan , Paras N. Prasad , Indrajit Roy , Stanley A. Schwartz , Ken-Tye Yong
发明人： Earl J. Bergey , Adela Bonoiu , Supriya Mahajan , Paras N. Prasad , Indrajit Roy , Stanley A. Schwartz , Ken-Tye Yong
IPC分类号： A61K31/7088 , A61P43/00
CPC分类号： C12N15/111 , A61K9/5115 , C12N15/113 , C12N2310/14 , C12N2320/32 , Y10S977/773
摘要： Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
摘要翻译： 提供了用于抑制一种或多种靶基因表达的方法和组合物。 组合物含有可通过与表面官能化金纳米棒（GNR）静电复合的RNA干扰（RNAi）抑制靶基因表达的RNA多核苷酸。 RNA多核苷酸不共价结合表面官能化的GNRs。 该方法涉及抑制个体中靶基因的表达。 该方法通过向个体施用有效量的含有可以通过RNAi抑制靶基因表达的RNA多核苷酸（例如siRNA）静电复合的表面官能化GNR的组合物来进行。 siRNA不与表面官能化的GNR共价结合。
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公开(公告)号：US20080128021A1
公开(公告)日：2008-06-05
申请号：US11850929
申请日：2007-09-06
申请人： Kaushik Roy Choudhury , Won Jin Kim , Yudhisthira Sahoo , Kwang Sup Lee , Paras N. Prasad , Alexander Cartwright , Ram B. Thapa
发明人： Kaushik Roy Choudhury , Won Jin Kim , Yudhisthira Sahoo , Kwang Sup Lee , Paras N. Prasad , Alexander Cartwright , Ram B. Thapa
CPC分类号： H01L51/426 , B82Y30/00 , H01L51/0035 , H01L51/0036 , H01L51/0038 , H01L51/0042 , Y02E10/549 , Y02P70/521
摘要： The present invention relates to a nanocomposite device comprising a polymeric matrix, semiconducting nanoparticles, and a semiconducting molecule having a field-effect mobility of at least 0.1 cm2/Vs. In addition, the present invention relates to a method of making a nanocomposite device. The method includes providing a mixture comprising a polymer, semiconducting nanoparticles, and a semiconducting molecule having a field-effect mobility of at least 0.1 cm2/Vs or a soluble precursor thereof, depositing the mixture on a substrate, and treating the mixture under conditions effective to produce a nanocomposite device comprising the polymeric matrix, semiconducting nanoparticles, and the semiconducting molecule having a field-effect mobility of at least 0.1 cm2/Vs. Thin film devices including the nanocomposite device are also disclosed.
摘要翻译： 本发明涉及包含聚合物基质，半导体纳米颗粒和具有至少0.1cm 2 / Vs的场效应迁移率的半导体分子的纳米复合材料装置。 另外，本发明涉及制造纳米复合器件的方法。 该方法包括提供包含聚合物，半导体纳米颗粒和具有至少0.1cm 2 / Vs的场效应迁移率的半导体分子或其可溶性前体的混合物，将该混合物沉积在基底上 并且在有效产生包含聚合物基质，半导体纳米颗粒和具有至少0.1cm 2 / Vs的场效应迁移率的半导体分子的纳米复合器件的条件下处理该混合物。 还公开了包括纳米复合器件的薄膜器件。
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17.发明授权Third order non-linear optically active composites, method of making same and photonic media comprising same 失效三阶非线性光学活性复合材料，其制备方法和包含其的光子介质
公开(公告)号：US5130362A
公开(公告)日：1992-07-14
申请号：US803667
申请日：1991-12-03
申请人： Paras N. Prasad , Frank E. Karasz , Yang Pang , Chichang J. Wung
发明人： Paras N. Prasad , Frank E. Karasz , Yang Pang , Chichang J. Wung
摘要： A composite having third order non-linear optical activity comprising, an organic polymer and an inorganic material. The organic polymer has third order nonlinear optical activity and the inorganic material is a sol-gel glass. The organic polymer or a precursor of the organic polymer is mutually soluble with a precursor of the sol-gel glass. The invention also includes photonic media having the above composite and a method of making the composite.
摘要翻译： 一种具有三阶非线性光学活性的复合材料，包括有机聚合物和无机材料。 有机聚合物具有三阶非线性光学活性，无机材料是溶胶 - 凝胶玻璃。 有机聚合物或有机聚合物的前体与溶胶 - 凝胶玻璃的前体相互溶解。 本发明还包括具有上述复合材料的光子介质和制备复合材料的方法。
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