公开(公告)号：US20140206025A1

公开(公告)日：2014-07-24

申请号：US14240311

申请日：2011-08-30

申请人： Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

发明人： Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

IPC分类号： G01N33/50

CPC分类号： G01N33/5091 ,  G01N33/57484 ,  G01N2333/904 ,  G01N2333/91188 ,  G01N2800/52

摘要： The present invention relates to a method for early evaluation of clinical efficacy of antitumor intervention measure, comprising evaluating the efficacy of the antitumor intervention measure by assaying whether the content of a tumor-damaging biomarker(s) in the blood of a patient having tumor rises as compared to the baseline level before treatment within a time window after the patients receives at least one antitumor intervention measure. In preferable embodiments, the tumor-damaging biomarker(s) is selected from a group consisting of Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Lactate Dehydrogenase (LDH); said tumor is multiple myeloma; said antitumor intervention measure is the administration of CPT alone or the administration of CPT in combination with thalidomide.

摘要翻译： 本发明涉及一种用于早期评估抗肿瘤干预措施的临床疗效的方法，包括通过测定患有肿瘤的患者的血液中的肿瘤损伤性生物标志物的含量是否上升来评估抗肿瘤干预措施的功效 与患者接受至少一种抗肿瘤干预措施后的时间窗内治疗前的基线水平相比。 在优选的实施方案中，肿瘤破坏性生物标志物选自丙氨酸氨基转移酶（ALT），天冬氨酸转氨酶（AST），乳酸脱氢酶（LDH）; 所述肿瘤是多发性骨髓瘤; 所述抗肿瘤干预措施是单独使用CPT或与沙利度胺组合使用CPT。

公开(公告)号：USD1014098S1

公开(公告)日：2024-02-13

申请号：US29889124

申请日：2023-04-08

申请人： Peng Wei

设计人： Peng Wei

摘要： FIG. 1 is a perspective view of a brush head, showing my new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation view thereof;
FIG. 4 is a left side elevation view thereof;
FIG. 5 is a right side elevation view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is a rear, top, and right side perspective view thereof; and,
FIG. 9 is an enlarged view of the portion labeled “9” encircled in FIG. 1.

公开(公告)号：US20080319163A1

公开(公告)日：2008-12-25

申请号：US11911201

申请日：2006-02-14

申请人： Yuliang Wang ,  Qinghai Sheng ,  Xinping Fang ,  Wenshui Xia ,  Hongmei Zhai ,  Peng Wei

发明人： Yuliang Wang ,  Qinghai Sheng ,  Xinping Fang ,  Wenshui Xia ,  Hongmei Zhai ,  Peng Wei

IPC分类号： C07K7/06

CPC分类号： A61K35/50 ,  A61K38/00 ,  C07K14/4715

摘要： The present invention provides a method for isolating and purifying immuno-modulating polypeptide from cow placenta, which is characterized by using the steps of anion-exchange chromatography, gel exclusion chromatography and reverse-phase high performance liquid chromatography to isolate and purify immuno-modulating polypeptide from cow placenta, identifying its activity of stimulating lymphocyte proliferation in vitro by MTT method, then determining its molecular weight by MALDI-TOF-MS, its isoelectric point by CIEF and its amino acid sequence with analyzer for protein sequencing. Since the obtained immuno-modulating polypeptide by the method according to the present invention has more than 90% purity, its bioactivity can reach medicinal standards.

摘要翻译： 本发明提供了一种从牛胎盘中分离和纯化免疫调节多肽的方法，其特征在于使用阴离子交换色谱法，凝胶排阻色谱法和反相高效液相色谱法分离和纯化免疫调节多肽 从牛胎盘中，通过MTT法鉴定其在体外刺激淋巴细胞增殖的活性，然后通过MALDI-TOF-MS测定其分子量，通过CIEF测定其等电点及其氨基酸序列与蛋白质测序分析仪。 由于通过本发明的方法获得的免疫调节多肽具有超过90％的纯度，因此其生物活性可达到医学标准。

公开(公告)号：US06806491B2

公开(公告)日：2004-10-19

申请号：US10351070

申请日：2003-01-24

申请人： Yong Qiu ,  Yudi Gao ,  Peng Wei ,  Deqiang Zhang ,  Liduo Wang

发明人： Yong Qiu ,  Yudi Gao ,  Peng Wei ,  Deqiang Zhang ,  Liduo Wang

IPC分类号： H01L5100

CPC分类号： H01L51/5048 ,  H01L51/0037 ,  H01L51/0042 ,  H01L51/0052 ,  H01L51/0059 ,  H01L51/0062 ,  H01L51/007 ,  H01L51/0077 ,  H01L51/0078 ,  H01L51/0081 ,  H01L51/5088 ,  Y10S977/95

摘要： An organic light-emitting device including a transparent substrate, a first electrode layer, a second electrode layer, a hole-transporting layer, and a electron-transporting layer sandwiched between the first and second electrode layers, wherein the hole-transporting layer consists of organic multiple-quantum-well structure. The multiple-quantum-well structure has a period number of alternating layers formed of a layer of organic material A with wide energy gap and a layer of organic material B with narrow energy gap. Organic material A and organic material B are selected such that the highest occupied molecular orbital (HOMO) levels of organic material A are lower than those of organic material B and the lowest unoccupied molecular orbital (LUMO) levels of organic material A are higher than those of organic material B.

摘要翻译： 一种有机发光装置，其包括透明基板，第一电极层，第二电极层，空穴传输层和夹在所述第一和第二电极层之间的电子传输层，其中所述空穴传输层由 有机多量子阱结构。 多量子阱结构具有由具有宽能隙的有机材料A层和具有窄能隙的有机材料B层形成的交替层的周期数。 选择有机材料A和有机材料B使得有机材料A的最高占据分子轨道（HOMO）水平低于有机材料B的有机材料B，并且有机材料A的最低未占分子轨道（LUMO）水平高于有机材料A 的有机材料B.

公开(公告)号：USD1002200S1

公开(公告)日：2023-10-24

申请号：US29892541

申请日：2023-05-18

申请人： Peng Wei

设计人： Peng Wei

摘要： FIG. 1 is a perspective view of a lint remover, showing my new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation view thereof;
FIG. 4 is a left side elevation view thereof;
FIG. 5 is a right side elevation view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is a rear, bottom, and left side perspective view thereof;
FIG. 9 is an exploded perspective view of a lint remover, viewed from front, left, and top direction; and,
FIG. 10 is a left side elevation view of FIG. 9.
The broken lines and greyed-out region illustrate portions of the article that form no part of the claimed design.

公开(公告)号：US11119462B2

公开(公告)日：2021-09-14

申请号：US16596093

申请日：2019-10-08

申请人： Renchang Dai ,  Guangyi Liu ,  Chen Yuan ,  Peng Wei ,  Yongli Zhu ,  Yi Lu ,  Zhijun Liao ,  Zhiwei Wang

发明人： Renchang Dai ,  Guangyi Liu ,  Chen Yuan ,  Peng Wei ,  Yongli Zhu ,  Yi Lu ,  Zhijun Liao ,  Zhiwei Wang

IPC分类号： G05B99/00 ,  G05B19/042

摘要： A power system energy management system with dynamic state estimation (DSE) is disclosed wherein system dynamic states are estimated using SCADA measurements, PMU measurements, signals of controllers, digital recorders, protection devices, and smart electronic devices. The DSE is solved first by Unscented Kalman Filter, and if the Unscented Kalman Filter is failed, weighted lease square is used to solve the DSE. If weighted lease square is failed, integration method is used to calculate the dynamic states. In another aspect, Unscented Kalman Filter, weighted lease square, and integration calculation are applied to solve the DSE by nodal parallel computing for each generation system.

公开(公告)号：US20210103263A1

公开(公告)日：2021-04-08

申请号：US16596093

申请日：2019-10-08

申请人： Renchang Dai ,  Guangyi Liu ,  Chen Yuan ,  Peng Wei ,  Yongli Zhu ,  Yi Lu ,  Zhijun Liao ,  Zhiwei Wang

发明人： Renchang Dai ,  Guangyi Liu ,  Chen Yuan ,  Peng Wei ,  Yongli Zhu ,  Yi Lu ,  Zhijun Liao ,  Zhiwei Wang

IPC分类号： G05B19/042

摘要： A power system energy management system with dynamic state estimation (DSE) is disclosed wherein system dynamic states are estimated using SCADA measurements, PMU measurements, signals of controllers, digital recorders, protection devices, and smart electronic devices. The DSE is solved first by Unscented Kalman Filter, and if the Unscented Kalman Filter is failed, weighted lease square is used to solve the DSE. If weighted lease square is failed, integration method is used to calculate the dynamic states. In another aspect, Unscented Kalman Filter, weighted lease square, and integration calculation are applied to solve the DSE by nodal parallel computing for each generation system.

公开(公告)号：US09289468B2

公开(公告)日：2016-03-22

申请号：US14344289

申请日：2011-09-16

申请人： Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

发明人： Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

IPC分类号： A61K38/16 ,  A61K38/12 ,  A61K38/00 ,  A61P35/00 ,  A61P35/02 ,  C07K1/00 ,  C07K14/00 ,  C07K17/00 ,  C07K16/00 ,  C12N1/20 ,  C12N15/00 ,  A61K39/00 ,  A61K39/385 ,  A61K38/17 ,  C07K14/715 ,  C07K14/47 ,  C07K14/525 ,  C12N15/63 ,  C12N15/62 ,  C07K14/705 ,  A61K45/06 ,  C07K14/52

CPC分类号： A61K38/1761 ,  A61K38/00 ,  A61K45/06 ,  C07K14/47 ,  C07K14/4747 ,  C07K14/52 ,  C07K14/525 ,  C07K14/70575 ,  C07K14/7151 ,  C07K2319/21 ,  C07K2319/33 ,  C12N15/62 ,  C12N15/63

摘要： Provided is a fusion protein comprising circularly permuted form of TRAIL, and the fusion protein contains circularly permuted form of TRAIL and oligopeptides located at the N-terminus and/or C-terminus of the permuted form. The oligopeptides contain a repeating sequence consisting of 3-10 histidines. The components of the circularly permuted form of TRAIL from N-terminus to C-terminus are: (a) amino acids 135-281 of TRAIL, (b) a linker, and (c) amino acids 121-135 of TRAIL or amino acids 114-135 of TRAIL or amino acids 95-135 of TRAIL or any fragments of amino acids 95-135 of TRAIL containing amino acids 121-135 of TRAIL. Also provided is a method for treating cancer by using the fusion protein.

摘要翻译： 提供了包含循环形式的TRAIL的融合蛋白，并且融合蛋白包含位于置换形式的N末端和/或C末端的循环形式的TRAIL和寡肽。 寡肽含有由3-10组氨酸组成的重复序列。 从N末端到C末端的循环形式的TRAIL的组分是：（a）TRAIL的氨基酸135-281，（b）接头，和（c）TRAIL或氨基酸的氨基酸121-135 TRAIL的114-135或TRAIL的氨基酸95-135或含有TRAIL的第121-135位氨基酸的TRAIL的任何氨基酸95-135的片段。 还提供了通过使用融合蛋白治疗癌症的方法。

公开(公告)号：US20120284147A1

公开(公告)日：2012-11-08

申请号：US13517912

申请日：2012-04-19

申请人： Qionglin Nie ,  Liang Yang ,  Renchen Huang ,  Yao Zhang ,  Peng Wei ,  Xiaolong Ma ,  Qun Wang

发明人： Qionglin Nie ,  Liang Yang ,  Renchen Huang ,  Yao Zhang ,  Peng Wei ,  Xiaolong Ma ,  Qun Wang

IPC分类号： G06Q30/06

CPC分类号： G06Q20/02 ,  G06Q20/12 ,  G06Q30/06

摘要： In a commerce transaction between a buyer and seller that involves transfer of an item, payment is made through an independent online payment system. A seller sends a threshold amount and a payment amount to a payment server for the transaction involving the item. The payment server creates an intermediate account based on the threshold amount and the payment amount. To proceed with the transaction, a buyer transfers a fund amount to the payment server. The payment server determines whether the fund amount is not less than the threshold amount, and if so, the payment server designates the fund amount as an account balance associated with the buyer in the intermediate account. The payment server then transfers funds corresponding to the payment amount from the intermediate account to an account designated by the seller after receiving a payment request indicating the buyer's receipt of the item.

摘要翻译： 在买卖双方涉及转让物品的商业交易中，通过独立的在线支付系统付款。 卖方向涉及该项目的交易的支付服务器发送阈值金额和支付金额。 支付服务器根据阈值金额和支付金额创建一个中间账户。 要进行交易，买方将支付金额转入付款服务器。 支付服务器确定基金金额是否不小于阈值金额，如果是，则支付服务器将基金金额指定为与中间账户中的买方相关联的账户余额。 然后，付款服务器在接收到指示买方接收到该项目的支付请求之后，将与中间帐户相对应的支付金额的资金转移到由卖方指定的账户。