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    Organic light-emitting devices
    1.
    发明授权
    Organic light-emitting devices 有权
    有机发光装置

    公开(公告)号：US06806491B2

    公开(公告)日：2004-10-19

    申请号：US10351070

    申请日：2003-01-24

    申请人： Yong Qiu ,  Yudi Gao ,  Peng Wei ,  Deqiang Zhang ,  Liduo Wang

    发明人： Yong Qiu ,  Yudi Gao ,  Peng Wei ,  Deqiang Zhang ,  Liduo Wang

    IPC分类号： H01L5100

    CPC分类号： H01L51/5048 ,  H01L51/0037 ,  H01L51/0042 ,  H01L51/0052 ,  H01L51/0059 ,  H01L51/0062 ,  H01L51/007 ,  H01L51/0077 ,  H01L51/0078 ,  H01L51/0081 ,  H01L51/5088 ,  Y10S977/95

    摘要： An organic light-emitting device including a transparent substrate, a first electrode layer, a second electrode layer, a hole-transporting layer, and a electron-transporting layer sandwiched between the first and second electrode layers, wherein the hole-transporting layer consists of organic multiple-quantum-well structure. The multiple-quantum-well structure has a period number of alternating layers formed of a layer of organic material A with wide energy gap and a layer of organic material B with narrow energy gap. Organic material A and organic material B are selected such that the highest occupied molecular orbital (HOMO) levels of organic material A are lower than those of organic material B and the lowest unoccupied molecular orbital (LUMO) levels of organic material A are higher than those of organic material B.

    摘要翻译： 一种有机发光装置，其包括透明基板，第一电极层，第二电极层，空穴传输层和夹在所述第一和第二电极层之间的电子传输层，其中所述空穴传输层由 有机多量子阱结构。 多量子阱结构具有由具有宽能隙的有机材料A层和具有窄能隙的有机材料B层形成的交替层的周期数。 选择有机材料A和有机材料B使得有机材料A的最高占据分子轨道（HOMO）水平低于有机材料B的有机材料B，并且有机材料A的最低未占分子轨道（LUMO）水平高于有机材料A 的有机材料B.

    n-Type doped organic materials and methods therefor
    4.
    发明授权
    n-Type doped organic materials and methods therefor 有权
    n型掺杂有机材料及其方法

    公开(公告)号：US09133130B2

    公开(公告)日：2015-09-15

    申请号：US13080564

    申请日：2011-04-05

    申请人： Peng Wei ,  Zhenan Bao

    发明人： Peng Wei ,  Zhenan Bao

    IPC分类号： H01L51/00 ,  H01L51/05 ,  H01L51/52 ,  C07D235/18 ,  B82Y10/00 ,  B82Y30/00 ,  C07D409/04 ,  C07D409/14

    CPC分类号： C07D235/18 ,  B82Y10/00 ,  B82Y30/00 ,  C07D409/04 ,  C07D409/14 ,  H01L51/0047 ,  H01L51/0048 ,  H01L51/005 ,  H01L51/0533 ,  H01L51/0545 ,  H01L51/0566 ,  H01L51/5004 ,  H01L51/5296 ,  Y02E10/549 ,  Y02P70/521

    摘要： In accordance with various embodiments, an organic electronic device includes an n-type dopant material including an imidazole-based material having a hydrogen-based material bonded between nitrogen atoms. The n-type dopant material n-dopes an organic material, and can be used to mitigate degradation in mobility due to conditions such as exposure to ambient atmosphere, which can effect an undesirable reduction in charge transport. Other embodiments are directed to carbon nanotubes or graphene structures with this type of n-type dopant, wherein the Fermi level for the carbon nanotubes or graphene structures is below −2.5 eV to effect such n-type doping.

    摘要翻译： 根据各种实施方案，有机电子器件包括n型掺杂剂材料，其包括在氮原子之间键合有氢基材料的咪唑类材料。 n型掺杂剂材料掺杂有机材料，并且可以用于减轻由于诸如暴露于环境大气的条件而导致的迁移率的降低，这可能导致电荷传输的不期望的减少。 其他实施方案涉及具有这种类型的n型掺杂剂的碳纳米管或石墨烯结构，其中碳纳米管或石墨烯结构的费米能级低于-2.5eV以实现这种n型掺杂。

    Fusion Protein Comprising Circularly Permuted Form Of Trail/Apo2L, Coding Gene And Use Thereof
    5.
    发明申请
    Fusion Protein Comprising Circularly Permuted Form Of Trail/Apo2L, Coding Gene And Use Thereof 有权
    融合蛋白包含循环形式的Trail / Apo2L，编码基因及其用途

    公开(公告)号：US20140342994A1

    公开(公告)日：2014-11-20

    申请号：US14344289

    申请日：2011-09-16

    申请人： Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

    发明人： Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

    IPC分类号： A61K38/17 ,  A61K45/06 ,  C07K14/47

    CPC分类号： A61K38/1761 ,  A61K38/00 ,  A61K45/06 ,  C07K14/47 ,  C07K14/4747 ,  C07K14/52 ,  C07K14/525 ,  C07K14/70575 ,  C07K14/7151 ,  C07K2319/21 ,  C07K2319/33 ,  C12N15/62 ,  C12N15/63

    摘要： Provided is a fusion protein comprising circularly permuted form of TRAIL, and the fusion protein contains circularly permuted form of TRAIL and oligopeptides located at the N-terminus and/or C-terminus of the permuted form. The oligopeptides contain a repeating sequence consisting of 3-10 histidines. The components of the circularly permuted form of TRAIL from N-terminus to C-terminus are: (a) amino acids 135-281 of TRAIL, (b) a linker, and (c) amino acids 121-135 of TRAIL or amino acids 114-135 of TRAIL or amino acids 95-135 of TRAIL or any fragments of amino acids 95-135 of TRAIL containing amino acids 121-135 of TRAIL. Also provided is a method for treating cancer by using the fusion protein.

    摘要翻译： 提供了包含循环形式的TRAIL的融合蛋白，并且融合蛋白包含位于置换形式的N末端和/或C末端的循环形式的TRAIL和寡肽。 寡肽含有由3-10组氨酸组成的重复序列。 从N末端到C末端的循环形式的TRAIL的组分是：（a）TRAIL的氨基酸135-281，（b）接头，和（c）TRAIL或氨基酸的氨基酸121-135 TRAIL的114-135或TRAIL的氨基酸95-135或含有TRAIL的第121-135位氨基酸的TRAIL的任何氨基酸95-135的片段。 还提供了通过使用融合蛋白治疗癌症的方法。

    Use Of Detection Of Aspartate Transaminase And Lactate Dehydrogenase In Early Evaluation Of Clinical Efficacy Of Antitumor Intervention Measure
    6.
    发明申请
    Use Of Detection Of Aspartate Transaminase And Lactate Dehydrogenase In Early Evaluation Of Clinical Efficacy Of Antitumor Intervention Measure 审中-公开
    使用天冬氨酸转氨酶和乳酸脱氢酶在早期评估抗肿瘤干预措施的临床疗效

    公开(公告)号：US20140206025A1

    公开(公告)日：2014-07-24

    申请号：US14240311

    申请日：2011-08-30

    申请人： Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

    发明人： Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

    IPC分类号： G01N33/50

    CPC分类号： G01N33/5091 ,  G01N33/57484 ,  G01N2333/904 ,  G01N2333/91188 ,  G01N2800/52

    摘要： The present invention relates to a method for early evaluation of clinical efficacy of antitumor intervention measure, comprising evaluating the efficacy of the antitumor intervention measure by assaying whether the content of a tumor-damaging biomarker(s) in the blood of a patient having tumor rises as compared to the baseline level before treatment within a time window after the patients receives at least one antitumor intervention measure. In preferable embodiments, the tumor-damaging biomarker(s) is selected from a group consisting of Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Lactate Dehydrogenase (LDH); said tumor is multiple myeloma; said antitumor intervention measure is the administration of CPT alone or the administration of CPT in combination with thalidomide.

    摘要翻译： 本发明涉及一种用于早期评估抗肿瘤干预措施的临床疗效的方法，包括通过测定患有肿瘤的患者的血液中的肿瘤损伤性生物标志物的含量是否上升来评估抗肿瘤干预措施的功效 与患者接受至少一种抗肿瘤干预措施后的时间窗内治疗前的基线水平相比。 在优选的实施方案中，肿瘤破坏性生物标志物选自丙氨酸氨基转移酶（ALT），天冬氨酸转氨酶（AST），乳酸脱氢酶（LDH）; 所述肿瘤是多发性骨髓瘤; 所述抗肿瘤干预措施是单独使用CPT或与沙利度胺组合使用CPT。

    Air-stable n-channel organic electronic devices
    7.
    发明授权
    Air-stable n-channel organic electronic devices 有权
    空气稳定的n沟道有机电子器件

    公开(公告)号：US09040400B2

    公开(公告)日：2015-05-26

    申请号：US13079879

    申请日：2011-04-05

    申请人： Peng Wei ,  Zhenan Bao ,  Joon Hak Oh

    发明人： Peng Wei ,  Zhenan Bao ,  Joon Hak Oh

    IPC分类号： H01L21/22 ,  H01L21/38 ,  H01L51/00 ,  B82Y10/00 ,  H01L51/05

    CPC分类号： H01L51/002 ,  B82Y10/00 ,  H01L51/0047 ,  H01L51/0094 ,  H01L51/0525 ,  H01L51/0545

    摘要： In connection with various example embodiments, an organic electronic device is provided with an organic material that is susceptible to decreased mobility due to the trapping of electron charge carriers in response to exposure to air. The organic material is doped with an n-type dopant that, when combined with the organic material, effects air stability for the doped organic material (e.g., exhibits a mobility that facilitates stable operation in air, such as may be similar to operation in inert environments). Other embodiments are directed to organic electronic devices n-doped and exhibiting such air stability.

    摘要翻译： 结合各种示例实施例，有机电子器件被提供有有机材料，其由于电子电荷载体响应于暴露于空气而被俘获而易于降低迁移率。 有机材料掺杂有n型掺杂剂，当与有机材料组合时，掺杂的有机材料具有空气稳定性（例如，表现出促进在空气中稳定运行的迁移率，例如可以类似于在惰性中的操作） 环境）。 其他实施方案涉及n掺杂并表现出这种空气稳定性的有机电子器件。

    AIR-STABLE N-CHANNEL ORGANIC ELECTRONIC DEVICES
    8.
    发明申请
    AIR-STABLE N-CHANNEL ORGANIC ELECTRONIC DEVICES 有权
    空气稳定的N沟道有机电子器件

    公开(公告)号：US20110248267A1

    公开(公告)日：2011-10-13

    申请号：US13079879

    申请日：2011-04-05

    申请人： Peng Wei ,  Zhenan Bao ,  Joon Hak Oh

    发明人： Peng Wei ,  Zhenan Bao ,  Joon Hak Oh

    IPC分类号： H01L21/22 ,  H01L29/04

    CPC分类号： H01L51/002 ,  B82Y10/00 ,  H01L51/0047 ,  H01L51/0094 ,  H01L51/0525 ,  H01L51/0545

    摘要： In connection with various example embodiments, an organic electronic device is provided with an organic material that is susceptible to decreased mobility due to the trapping of electron charge carriers in response to exposure to air. The organic material is doped with an n-type dopant that, when combined with the organic material, effects air stability for the doped organic material (e.g., exhibits a mobility that facilitates stable operation in air, such as may be similar to operation in inert environments). Other embodiments are directed to organic electronic devices n-doped and exhibiting such air stability.

    摘要翻译： 结合各种示例实施例，有机电子器件被提供有有机材料，其由于电子电荷载体响应于暴露于空气而被俘获而易于降低迁移率。 有机材料掺杂有n型掺杂剂，当与有机材料组合时，掺杂的有机材料具有空气稳定性（例如，表现出促进在空气中稳定运行的迁移率，例如可以类似于在惰性中的操作） 环境）。 其他实施方案涉及n掺杂并表现出这种空气稳定性的有机电子器件。

    Method for Isolating and Purifying Immuno-Modulating Polypeptide from Cow Placenta
    9.
    发明申请
    Method for Isolating and Purifying Immuno-Modulating Polypeptide from Cow Placenta 审中-公开
    牛胎盘分离和纯化免疫调节多肽的方法

    公开(公告)号：US20080319163A1

    公开(公告)日：2008-12-25

    申请号：US11911201

    申请日：2006-02-14

    申请人： Yuliang Wang ,  Qinghai Sheng ,  Xinping Fang ,  Wenshui Xia ,  Hongmei Zhai ,  Peng Wei

    发明人： Yuliang Wang ,  Qinghai Sheng ,  Xinping Fang ,  Wenshui Xia ,  Hongmei Zhai ,  Peng Wei

    IPC分类号： C07K7/06

    CPC分类号： A61K35/50 ,  A61K38/00 ,  C07K14/4715

    摘要： The present invention provides a method for isolating and purifying immuno-modulating polypeptide from cow placenta, which is characterized by using the steps of anion-exchange chromatography, gel exclusion chromatography and reverse-phase high performance liquid chromatography to isolate and purify immuno-modulating polypeptide from cow placenta, identifying its activity of stimulating lymphocyte proliferation in vitro by MTT method, then determining its molecular weight by MALDI-TOF-MS, its isoelectric point by CIEF and its amino acid sequence with analyzer for protein sequencing. Since the obtained immuno-modulating polypeptide by the method according to the present invention has more than 90% purity, its bioactivity can reach medicinal standards.

    摘要翻译： 本发明提供了一种从牛胎盘中分离和纯化免疫调节多肽的方法，其特征在于使用阴离子交换色谱法，凝胶排阻色谱法和反相高效液相色谱法分离和纯化免疫调节多肽 从牛胎盘中，通过MTT法鉴定其在体外刺激淋巴细胞增殖的活性，然后通过MALDI-TOF-MS测定其分子量，通过CIEF测定其等电点及其氨基酸序列与蛋白质测序分析仪。 由于通过本发明的方法获得的免疫调节多肽具有超过90％的纯度，因此其生物活性可达到医学标准。