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公开(公告)号：US20050064543A1
公开(公告)日：2005-03-24
申请号：US10487078
申请日：2002-08-15
申请人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号：US20050033018A1
公开(公告)日：2005-02-10
申请号：US10477714
申请日：2002-05-16
申请人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
发明人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
IPC分类号： G01N33/50 , A61K45/00 , A61K49/00 , A61P1/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/06 , C07K14/47 , C07K14/705 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明提供鉴定和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与REMAP的异常表达相关的紊乱的方法。
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公开(公告)号：US20050191690A1
公开(公告)日：2005-09-01
申请号：US11100583
申请日：2005-04-07
申请人： Preeti Lal , Mariah Baughn , April Hafalia , Danniel Nguyen , Ameena Gandhi , Deborah Kallick , Jennifer Griffin , Henry Yue , Farrah Khan , Chandra Arvizu , Dyung M. Lu , Catherine Tribouley , Yan Lu , Narinder Chawla , Richard Graul , Monique Yao , Junming Yang , Jayakaxmi Ramkumar , Janice Au-Young , Vicki Elliott , Roberto Hernandez , Roderick Walsh , Mark Borowsky , Michael Thornton , Ann He
发明人： Preeti Lal , Mariah Baughn , April Hafalia , Danniel Nguyen , Ameena Gandhi , Deborah Kallick , Jennifer Griffin , Henry Yue , Farrah Khan , Chandra Arvizu , Dyung M. Lu , Catherine Tribouley , Yan Lu , Narinder Chawla , Richard Graul , Monique Yao , Junming Yang , Jayakaxmi Ramkumar , Janice Au-Young , Vicki Elliott , Roberto Hernandez , Roderick Walsh , Mark Borowsky , Michael Thornton , Ann He
IPC分类号： G01N33/50 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P3/00 , A61P9/00 , A61P25/00 , A61P31/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705 , A61K38/00
摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译： 本发明提供鉴定和编码GCREC的人G-蛋白偶联受体（GCREC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与GCREC异常表达相关的疾病的方法。
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公开(公告)号：US20070134680A1
公开(公告)日：2007-06-14
申请号：US11377409
申请日：2006-03-17
申请人： Y. Tang , Yalda Azimzai , Debopriya Das , Michael Thornton , Dyung Lu , Catherine Tribouley , Henry Yue , Ameena Gandhi , Narinder Chawla , Farrah Khan , Yan Lu , Monique Yao , April Hafalia , Vicki Elliott , Chandra Arvizu , Preeti Lal , Jayalaxmi Ramkumar , Danniel Nguyen , Mariah Baughn
发明人： Y. Tang , Yalda Azimzai , Debopriya Das , Michael Thornton , Dyung Lu , Catherine Tribouley , Henry Yue , Ameena Gandhi , Narinder Chawla , Farrah Khan , Yan Lu , Monique Yao , April Hafalia , Vicki Elliott , Chandra Arvizu , Preeti Lal , Jayalaxmi Ramkumar , Danniel Nguyen , Mariah Baughn
CPC分类号： C12Y301/01043 , A61K38/00 , C07H21/04 , C07K14/47 , C12N9/20
摘要： The invention provides human lipid metabolism molecules (LMM) and polynucleotides which identify and encode LMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LMM.
摘要翻译： 本发明提供了人类脂质代谢分子（LMM）和识别和编码LMM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与LMM的异常表达相关的障碍的方法。
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公开(公告)号：US20060024792A1
公开(公告)日：2006-02-02
申请号：US11241956
申请日：2005-10-04
申请人： Mariah Baughn , Richard Graul , Narinder Chawla , Ameena Gandhi , April Hafalia , Jayalaxmi Ramkumar , Catherine Tribouley , Michael Thornton , Deborah Kallick , Monique Yao , Vicki Elliott , Neil Burford , Farrah Khan , Henry Yue , Yan Lu , Chandra Arvizu , Roopa Reddy , Danniel Nguyen , Ernestine Lee , Dyung Lu , Craig Ison , Roderick Walsh , Jennifer Policky
发明人： Mariah Baughn , Richard Graul , Narinder Chawla , Ameena Gandhi , April Hafalia , Jayalaxmi Ramkumar , Catherine Tribouley , Michael Thornton , Deborah Kallick , Monique Yao , Vicki Elliott , Neil Burford , Farrah Khan , Henry Yue , Yan Lu , Chandra Arvizu , Roopa Reddy , Danniel Nguyen , Ernestine Lee , Dyung Lu , Craig Ison , Roderick Walsh , Jennifer Policky
IPC分类号： C07H21/04 , C12P21/06 , C07K14/705 , C12N1/21
CPC分类号： C07K14/705
摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
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公开(公告)号：US20050107588A1
公开(公告)日：2005-05-19
申请号：US10495148
申请日：2002-11-13
申请人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号： C07K14/47 , C07K14/705 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050048479A1
公开(公告)日：2005-03-03
申请号：US10311625
申请日：2001-06-26
申请人： Ameena Gandhi , Catherine Tribouley , Li Ding , Dyung Lu , Ernestine Lee , Henry Yue , Junming Yang , Mariah Baughn , Michael Thornton , Monique Yao , Narinder Chawla , Y Tang , Vicki Elliott , Yan Lu
发明人： Ameena Gandhi , Catherine Tribouley , Li Ding , Dyung Lu , Ernestine Lee , Henry Yue , Junming Yang , Mariah Baughn , Michael Thornton , Monique Yao , Narinder Chawla , Y Tang , Vicki Elliott , Yan Lu
IPC分类号： G01N33/50 , A61K38/00 , A61K38/51 , A61K45/00 , A61P9/00 , A61P15/00 , A61P21/00 , A61P21/04 , A61P25/00 , A61P27/00 , A61P43/00 , C07K16/40 , C07K16/46 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/88 , C12N15/09 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/573 , A01K67/00 , C07H21/04 , C12N9/22
CPC分类号： C12N9/88 , A01K2217/05 , A61K38/00 , C12Y406/01001 , C12Y406/01002
摘要： The invention provides human adenylyl and guanylyl cyclases (ADGUC) and polynucleotides which identify and encode ADGUC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ADGUC.
摘要翻译： 本发明提供鉴定和编码ADGUC的人腺苷酰和鸟苷酸环化酶（ADGUC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与ADGUC的异常表达相关的紊乱的方法。
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公开(公告)号：US20050227280A1
公开(公告)日：2005-10-13
申请号：US11140224
申请日：2005-05-31
申请人： Angelo Delegeane , Preeti Lal , April Hafalia , Chandra Arvizu , Narinder Chawla , Liam Kearney , Catherine Tribouley , Farrah Khan , Monique Yao , Mariah Baughn , Yalda Azimzai , Vicki Elliott , Danniel Nguyen , Ameena Gandhi , Junming Yang , Roberto Hernandez , Jennifer Policky , Dyung Aina Lu , Roopa Reddy , Henry Yue , Y. Tang
发明人： Angelo Delegeane , Preeti Lal , April Hafalia , Chandra Arvizu , Narinder Chawla , Liam Kearney , Catherine Tribouley , Farrah Khan , Monique Yao , Mariah Baughn , Yalda Azimzai , Vicki Elliott , Danniel Nguyen , Ameena Gandhi , Junming Yang , Roberto Hernandez , Jennifer Policky , Dyung Aina Lu , Roopa Reddy , Henry Yue , Y. Tang
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/10 , A61P1/16 , A61P3/10 , A61P7/02 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/10 , A61P21/04 , A61P25/00 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/48 , C12N9/64 , C12N15/09 , C12N15/55 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C12N9/6421 , A61K38/00 , C07H21/04 , C12N9/48
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
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公开(公告)号：US20060115813A1
公开(公告)日：2006-06-01
申请号：US10480962
申请日：2002-06-06
申请人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
发明人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号：US20070082341A1
公开(公告)日：2007-04-12
申请号：US11275596
申请日：2006-01-18
申请人： Preeti Lal , Monique Yao , Henry Yue , Ameena Gandhi , Y. Tang , Farrah Khan , Danniel Nguyen , Jennifer Policky , Debopriya Das , Jennifer Hillman , Narinder Walia , April Hafalia , Catherine Tribouley
发明人： Preeti Lal , Monique Yao , Henry Yue , Ameena Gandhi , Y. Tang , Farrah Khan , Danniel Nguyen , Jennifer Policky , Debopriya Das , Jennifer Hillman , Narinder Walia , April Hafalia , Catherine Tribouley
CPC分类号： C12N15/52 , A61K38/00 , C07K14/47 , C07K16/40 , C12Q1/6883
摘要： The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.
摘要翻译： 本发明提供了人类脂质代谢酶（LME）和识别和编码LME的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与LME异常表达相关的紊乱的方法。
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