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公开(公告)号:US20050107588A1
公开(公告)日:2005-05-19
申请号:US10495148
申请日:2002-11-13
申请人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号: C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , C07K14/47
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白(REMAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050176944A1
公开(公告)日:2005-08-11
申请号:US10487092
申请日:2002-08-16
申请人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人: Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号: C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要: Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译: 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子(INTSIG)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号:US20050123912A1
公开(公告)日:2005-06-09
申请号:US10486977
申请日:2002-08-14
申请人: Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人: Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号: C07K14/4702 , A61K38/00 , G01N2500/00
摘要: Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译: 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白(NAAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050064543A1
公开(公告)日:2005-03-24
申请号:US10487078
申请日:2002-08-15
申请人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人: Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号: G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要: Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US20050130145A1
公开(公告)日:2005-06-16
申请号:US10491355
申请日:2002-10-03
申请人: Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
发明人: Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
IPC分类号: A01K67/027 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/00 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , G01N37/00 , A61K38/17 , C07H21/04 , C12N9/00
CPC分类号: C07K14/47 , A01K2217/05 , C12N9/6421
摘要: Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US20060121459A1
公开(公告)日:2006-06-08
申请号:US10504973
申请日:2003-02-18
申请人: Narinder Chawla , Henry Yue , Thomas Richardson , Joseph Marquis , Patricia Lehr-Mason , Ann Gorvad , Shanya Becha , Amy Kable , Anita Swarnakar , Pei Jin , Phillip Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen Tran , April Hafalia , Mariah Baughn , Soo Lee , Xin Jiang , Alan Jackson , Reena Khare , Sean Bulloch
发明人: Narinder Chawla , Henry Yue , Thomas Richardson , Joseph Marquis , Patricia Lehr-Mason , Ann Gorvad , Shanya Becha , Amy Kable , Anita Swarnakar , Pei Jin , Phillip Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen Tran , April Hafalia , Mariah Baughn , Soo Lee , Xin Jiang , Alan Jackson , Reena Khare , Sean Bulloch
CPC分类号: C07K14/705 , C07K16/28
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码REMAP的人受体和膜相关蛋白(REMAP)和Q多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号:US20070225218A1
公开(公告)日:2007-09-27
申请号:US10481700
申请日:2002-06-26
申请人: Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
发明人: Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
IPC分类号: C12P21/00 , A61K38/00 , C07H21/04 , C07K14/00 , C12Q1/68 , G01N33/53 , C07K16/18 , C12N15/00 , C12N5/06
摘要: Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译: 本发明的各种实施方案提供了识别和编码EXMES的人细胞外信使(EXMES)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与异常表达EXMES相关的紊乱的方法。
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