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11.发明申请Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure 有权系统，装置和方法，包括被配置为监测生物膜形成的导管，其具有被配置为数据结构的生物膜谱信息公开(公告)号：US20110152978A1
公开(公告)日：2011-06-23
申请号：US12927294
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
IPC分类号： A61N5/06
CPC分类号： A61L2/0011
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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12.发明授权Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject 有权用于向哺乳动物受试者靶向递送抗炎药物的装置，系统和方法公开(公告)号：US09078863B2
公开(公告)日：2015-07-14
申请号：US12590860
申请日：2009-11-13
申请人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61M31/00 , A61K31/192 , A61B5/00 , A61B5/11 , A61K31/195 , A61M37/00 , A61M5/30
CPC分类号： A61K31/192 , A61B5/1116 , A61B5/112 , A61B5/1126 , A61B5/4528 , A61K31/195 , A61M37/0015 , A61M2005/3022 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061
摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more substrates configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more microjet applicators supported by the one or more substrates and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.
摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括被配置为接触靠近哺乳动物受试者的关节骨的一个或多个关节的一个或多个身体轮廓的一个或多个基底; 一个或多个传感器被配置为检测所述一个或多个关节的一个或多个生理状况; 以及一个或多个由一个或多个基底支撑并且经配置以通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应于一个或多个传感器的微喷射施加器。
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13.发明授权Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject 有权用于向哺乳动物受试者靶向递送抗炎药物的装置，系统和方法公开(公告)号：US09050303B2
公开(公告)日：2015-06-09
申请号：US12661079
申请日：2010-03-09
申请人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61M31/00 , A61K31/192 , A61B5/00 , A61B5/11 , A61K31/195 , A61M37/00 , A61M5/30
CPC分类号： A61K31/192 , A61B5/1116 , A61B5/112 , A61B5/1126 , A61B5/4528 , A61K31/195 , A61M37/0015 , A61M2005/3022 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061
摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more sheaths configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more applicators supported by the one or more sheaths and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.
摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括构造成接触哺乳动物受试者的关节骨的一个或多个关节附近的一个或多个身体轮廓的一个或多个护套; 一个或多个传感器被配置为检测所述一个或多个关节的一个或多个生理状况; 以及由所述一个或多个护套支撑并且被配置为通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应所述一个或多个传感器的一个或多个施用器。
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14.发明授权公开(公告)号：US09005263B2
公开(公告)日：2015-04-14
申请号：US12592976
申请日：2009-12-03
申请人： Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61F7/12 , A61L2/03 , A61F2/30 , A61L2/00 , A61F2/00 , A61F2/48 , A61N1/20 , A61N1/372 , A61N1/378
CPC分类号： A61F2/02 , A61F2/30 , A61F2002/009 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/3068 , A61F2002/3084 , A61F2002/30932 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2250/0068 , A61F2310/00616 , A61L2/0011 , A61L2/0023 , A61L2/0029 , A61L2/0088 , A61L2/025 , A61L2/03 , A61N1/205 , A61N1/36 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
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公开(公告)号：US08789536B2
公开(公告)日：2014-07-29
申请号：US11998152
申请日：2007-11-27
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： A61M31/002 , A61B5/0008 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/42 , A61B5/4839 , A61B5/6882 , A61B7/008
摘要： Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.
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16.发明授权Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter 失效包括具有可声学致动的波导部件的导管的系统，装置和方法，用于将消毒刺激递送到靠近导管表面的区域公开(公告)号：US08753304B2
公开(公告)日：2014-06-17
申请号：US12927285
申请日：2010-11-10
申请人： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61M5/00
CPC分类号： A61L2/14 , A61F2/32 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2310/0097 , A61L2/0011 , A61L2/08 , A61L2202/14 , A61L2202/24 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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公开(公告)号：US08394638B2
公开(公告)日：2013-03-12
申请号：US12291542
申请日：2008-11-10
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： G01N37/00
CPC分类号： A61K49/0002 , G01N33/58 , Y10T436/13 , Y10T436/24
摘要： A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.
摘要翻译： 系统可以包括用于向受试者施用治疗剂的装置; 至少基本上与治疗剂同时地向受试者施用第一药学上可接受的标签剂的方法，所述第一药学上可接受的标记剂具有药代动力学特征; 第二药学上可接受的标签剂具有与第一药学上可接受的标签剂的药代动力学特征不同的药代动力学特征的方法。
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公开(公告)号：US08282593B2
公开(公告)日：2012-10-09
申请号：US12800791
申请日：2010-05-21
申请人： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61M5/00
CPC分类号： A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
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19.发明申请Systems, devices, and methods including catheters having UV-Energy emitting coatings 审中-公开包括具有UV能发射涂层的导管的系统，装置和方法公开(公告)号：US20110152751A1
公开(公告)日：2011-06-23
申请号：US12927296
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
CPC分类号： A61L2/0011
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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20.发明授权Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject 有权用于向哺乳动物受试者靶向递送抗炎药物的装置，系统和方法公开(公告)号：US08894630B2
公开(公告)日：2014-11-25
申请号：US12590859
申请日：2009-11-13
申请人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22 , A61K31/192 , A61K31/195
CPC分类号： A61K31/192 , A61K31/195
摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more substrates configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to monitor movement of the one or more body contours; and one or more applicators supported by the one or more substrates and configured to respond to the movement of the one or more body contours by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.
摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括被配置为接触靠近哺乳动物受试者的关节骨的一个或多个关节的一个或多个身体轮廓的一个或多个基底; 一个或多个传感器被配置为监测所述一个或多个身体轮廓的运动; 以及一个或多个施用器，由一个或多个基底支撑并且构造成通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应一个或多个身体轮廓的移动。
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