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公开(公告)号：US20060036089A1
公开(公告)日：2006-02-16
申请号：US11240769
申请日：2005-10-03
申请人： Daniel Soppet , Paul Moore , Yanggu Shi , Steven Ruben , Craig Rosen , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Paul Young , George Komatsoulis , Jian Ni
发明人： Daniel Soppet , Paul Moore , Yanggu Shi , Steven Ruben , Craig Rosen , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Paul Young , George Komatsoulis , Jian Ni
IPC分类号： C07H21/04 , C12P21/06 , C07K14/705 , C07K14/47
摘要： The present invention relates to 33 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及33种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050208619A1
公开(公告)日：2005-09-22
申请号：US10878523
申请日：2004-06-29
申请人： Craig Rosen , Steven Ruben , Reinhard Ebner , Roxanne Duan , Jian Ni , Daniel Soppet , Paul Moore , Yanggu Shi , David LaFleur , Henrik Olsen , Charles Birse , George Komatsoulis
发明人： Craig Rosen , Steven Ruben , Reinhard Ebner , Roxanne Duan , Jian Ni , Daniel Soppet , Paul Moore , Yanggu Shi , David LaFleur , Henrik Olsen , Charles Birse , George Komatsoulis
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P9/10 , A61P17/02 , A61P17/06 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/00 , A61P31/04 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C07H21/04 , C07K14/47 , C07K16/18 , C07K2317/622 , C07K2319/30
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050010042A1
公开(公告)日：2005-01-13
申请号：US10919272
申请日：2004-08-17
申请人： Steven Ruben , Charles Birse , Roxanne Duan , Daniel Soppet , Craig Rosen , Yanggu Shi , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Jian Ni , Paul Young
发明人： Steven Ruben , Charles Birse , Roxanne Duan , Daniel Soppet , Craig Rosen , Yanggu Shi , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Jian Ni , Paul Young
IPC分类号： G01N33/50 , A61K31/711 , A61K38/00 , A61P1/04 , A61P7/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/06 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , G01N33/15 , G01N33/53 , C12Q1/68 , C07H21/04
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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公开(公告)号：US20050019866A1
公开(公告)日：2005-01-27
申请号：US10883936
申请日：2004-07-06
申请人： Jian Ni , Kevin Baker , Charles Birse , Michele Fiscella , George Komatsoulis , Craig Rosen , Daniel Soppet , Paul Young , Reinhard Ebner , D. Duan , Henrik Olsen , David La Fleur , Paul Moore , Yanggu Shi , Ping Wei , Kimberly Florence
发明人： Jian Ni , Kevin Baker , Charles Birse , Michele Fiscella , George Komatsoulis , Craig Rosen , Daniel Soppet , Paul Young , Reinhard Ebner , D. Duan , Henrik Olsen , David La Fleur , Paul Moore , Yanggu Shi , Ping Wei , Kimberly Florence
IPC分类号： G01N33/50 , A61K38/00 , A61K48/00 , A61P43/00 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04 , C12N9/42
CPC分类号： C07K14/70532 , A61K38/00 , C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050042667A1
公开(公告)日：2005-02-24
申请号：US10935098
申请日：2004-09-08
申请人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
发明人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
IPC分类号： C12N15/09 , A61K31/711 , A61K38/00 , A61K39/395 , A61K48/00 , A61P5/00 , A61P7/00 , A61P11/06 , A61P19/02 , A61P29/00 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K14/435 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/21 , C12N5/10 , C12Q1/68 , C07H21/04 , C12N9/00
摘要： The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及36种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20080020969A1
公开(公告)日：2008-01-24
申请号：US11780874
申请日：2007-07-20
申请人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
发明人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
IPC分类号： A61K38/00 , A61K48/00 , C07H21/00 , C07K14/00 , C12N15/00 , C12N15/87 , C12N5/06 , C12P21/04 , G01N33/53
摘要： The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及36种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20050032168A1
公开(公告)日：2005-02-10
申请号：US10896972
申请日：2004-07-23
申请人： Craig Rosen , George Komatsoulis , Kevin Baker , Charles Birse , Daniel Soppet , Henrik Olsen , Paul Moore , Ping Wei , Reinhard Ebner , D. Duan , Yanggu Shi , Gil Choi , Michele Fiscella , Jian Ni , Steven Ruben , Steven Barash
发明人： Craig Rosen , George Komatsoulis , Kevin Baker , Charles Birse , Daniel Soppet , Henrik Olsen , Paul Moore , Ping Wei , Reinhard Ebner , D. Duan , Yanggu Shi , Gil Choi , Michele Fiscella , Jian Ni , Steven Ruben , Steven Barash
IPC分类号： C12N15/09 , A61K31/00 , A61K31/7088 , A61K31/713 , A61K38/00 , A61K38/16 , A61K38/43 , A61K38/51 , A61K39/395 , A61K48/00 , A61P1/00 , A61P9/00 , A61P15/00 , A61P21/00 , A61P25/00 , A61P35/00 , A61P43/00 , C07H21/04 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/64 , C12N9/88 , C12N15/12 , C12N15/52 , C12N15/60 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/53 , G01N33/68
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K48/00 , A61K2039/505 , C07K14/705 , C07K16/18 , C07K2319/30 , C12N9/6424 , C12N2799/026 , C12Q1/6883 , G01N2500/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070015908A1
公开(公告)日：2007-01-18
申请号：US10866878
申请日：2004-06-15
申请人： Carrie Fischer , Craig Rosen , Daniel Soppet , Steven Ruben , Hla Kyaw , Yi Li , Zhizhen Zeng , David LaFleur , Paul Moore , Yanggu Shi , Henrik Olsen , Reinhard Ebner , Charles Birse
发明人： Carrie Fischer , Craig Rosen , Daniel Soppet , Steven Ruben , Hla Kyaw , Yi Li , Zhizhen Zeng , David LaFleur , Paul Moore , Yanggu Shi , Henrik Olsen , Reinhard Ebner , Charles Birse
CPC分类号： A01C23/024 , A61K38/00 , C07K14/47 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/5041 , G01N33/5047 , G01N33/505 , G01N33/5058 , G01N33/5091 , G01N33/68 , G01N33/6842 , G01N2500/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050064458A1
公开(公告)日：2005-03-24
申请号：US10863332
申请日：2004-06-09
申请人： Craig Rosen , Steven Ruben , Paul Moore , Paul Young , George Komatsoulis , Charles Birse , Roxanne Duan , Kimberly Florence , Daniel Soppet
发明人： Craig Rosen , Steven Ruben , Paul Moore , Paul Young , George Komatsoulis , Charles Birse , Roxanne Duan , Kimberly Florence , Daniel Soppet
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K39/395 , A61K48/00 , A61P1/04 , A61P7/00 , A61P7/04 , A61P7/06 , A61P9/10 , A61P11/06 , A61P17/02 , A61P17/06 , A61P17/12 , A61P19/02 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/04 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/566 , C07H21/04 , C12N9/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060099575A9
公开(公告)日：2006-05-11
申请号：US09949925
申请日：2001-09-12
申请人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
发明人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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