-
公开(公告)号：US20180103861A1
公开(公告)日：2018-04-19
申请号：US15565044
申请日：2016-04-11
IPC分类号： A61B5/03 , A61B5/0205 , A61B5/026 , A61B5/0402 , A61B5/0476 , A61B5/029 , A61B5/00
CPC分类号： A61B5/031 , A61B5/0075 , A61B5/0205 , A61B5/021 , A61B5/0261 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/08 , A61B5/14546 , A61B5/14552 , A61B5/6814 , A61B5/7246 , A61B5/7278 , A61B2562/0238
摘要： A system and method for non-invasively monitoring intracranial pressure are provided. In some aspects, the method comprises acquiring diffuse correlation spectroscopy data at a temporal resolution greater than a pulsatile frequency of cerebral blood flow of a subject using one or more optical sensors placed about a subject, and determining a pulsatile cerebral blood flow using the acquired data, The method also includes correlating the determined pulsatile cerebral blood flow with physiological data acquired from the subject, and estimating an intracranial pressure based on the correlation. The method further includes generating a report indicative of the estimated intracranial pressure.
-
公开(公告)号：US10912504B2
公开(公告)日：2021-02-09
申请号：US15111721
申请日：2015-01-14
申请人： Canon U.S.A. Inc. , The General Hospital Corporation , Haruo Nakaji , Maria Angela Franceschini , David Boas , Erin Buckley , Pei-Yi Lin , Stefan Carp
发明人： Haruo Nakaji , Maria Angela Franceschini , David Boas , Erin Buckley , Pei-Yi Lin , Stefan Carp
IPC分类号： A61B5/1455 , A61B5/026 , A61B5/00 , A61B5/145
摘要： There is provided herewith an apparatus, probe, and method for the combination of near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). The apparatus, probe and method allow for the simultaneous detection of NIRS and DCS.
-
公开(公告)号：US20200375476A1
公开(公告)日：2020-12-03
申请号：US16970670
申请日：2019-02-18
发明人： Maria Angela Franceschini , Stefan Carp , Davide Tamborini , David Boas , Bruce Rosen , Megan Blackwell , Oleg Shatrovoy
摘要： An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.
-
公开(公告)号：US20180070831A1
公开(公告)日：2018-03-15
申请号：US15564686
申请日：2016-04-11
IPC分类号： A61B5/00 , A61B5/026 , A61B5/0205
CPC分类号： A61B5/031 , A61B5/0075 , A61B5/0205 , A61B5/021 , A61B5/0261 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/08 , A61B5/14546 , A61B5/14552 , A61B5/6814 , A61B5/7246 , A61B5/7278 , A61B2562/0238
摘要： A system and method for non-invasively estimating an absolute blood flow of a vascular region in a subject using optical data are provided. In some aspects, the method includes acquiring optical data from the vascular region using one or more optical sensors placed about the subject, and determining, using the optical data, an index of blood flow and. a blood volume associated with the vascular region. The method also includes computing a blood inflow and a blood outflow using the index of blood flow and the blood volume, and estimating an absolute blood flow using the blood inflow and blood outflow. The method further includes generating a report indicative of the absolute blood flow of the vascular region.
-
15.发明申请公开(公告)号：US20170248518A1
公开(公告)日：2017-08-31
申请号：US15431372
申请日：2017-02-13
IPC分类号： G01N21/47 , G01N33/483
CPC分类号： G01N21/4788 , G01N15/0211 , G01N21/4795 , G01N33/4833 , G01N2015/0065 , G01N2015/0222 , G01N2021/479 , G01N2021/4792
摘要： Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus. Speckle frames may be acquired by illuminating a coherent light and capturing back-scattered rays in parallel and cross-polarized states with respect to illumination. The speckle frames may be analyzed temporally to obtain diffuse reflectance profiles (DRPs) for the parallel-polarized and cross-polarized states. A scattering characteristic of particles in the biological tissue may be determined based on the DRPs, and a displacement characteristic may be determined based at least in part on a speckle intensity autocorrelation function and the scattering characteristic. A size characteristic of scattering particles may be determined based on the DRP for the parallel polarization state. The mechanical property may be calculated using the displacement and size characteristics.
-
16.发明申请NEAR-INFRARED SPECTROSCOPY AND DIFFUSE CORRELATION SPECTROSCOPY DEVICE AND METHODS 审中-公开近红外光谱和差分相关光谱仪器及方法公开(公告)号：US20160345880A1
公开(公告)日：2016-12-01
申请号：US15111721
申请日：2015-01-14
申请人： Haruo NAKAJI , Maria FRANCESCHIN , Davis BOAS , Erin BUCKLEY , Pei-Yi LIN , Stefan CARP , CANON U.S.A. INC. , THE GENERAL HOSPITAL CORPORATION
发明人： Haruo Nakaji , Maria Angela Franceschini , David Boas , Erin Buckley , Pei-Yi Lin , Stefan Carp
IPC分类号： A61B5/1455 , A61B5/145 , A61B5/00 , A61B5/026
CPC分类号： A61B5/14552 , A61B5/0261 , A61B5/14546 , A61B5/14553 , A61B5/4064 , A61B5/4866 , A61B5/7225 , A61B5/7278 , A61B2562/0233 , A61B2562/0238
摘要： There is provided herewith an apparatus, probe, and method for the combination of near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). The apparatus, probe and method allow for the simultaneous detection of NIRS and DCS.
摘要翻译： 本发明提供了用于近红外光谱（NIRS）和扩散相关光谱（DCS）组合的装置，探针和方法。 该装置，探头和方法允许同时检测NIRS和DCS。
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.024 秒)
