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公开(公告)号：US20200339730A1
公开(公告)日：2020-10-29
申请号：US16924819
申请日：2020-07-09
Inventor： Keith Hearon , Landon D. Nash , Thomas Wilson , Duncan J. Maitland , Mark A. Wierzbicki
Abstract: An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.
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公开(公告)号：US20200222595A1
公开(公告)日：2020-07-16
申请号：US16777190
申请日：2020-01-30
Applicant: The Texas A&M University System
Inventor： Rachael Muschalek , Keith Hearon , Landon D. Nash , Duncan J. Maitland
Abstract: An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.
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公开(公告)号：US10265433B2
公开(公告)日：2019-04-23
申请号：US14661215
申请日：2015-03-18
Inventor： Duncan J. Maitland , Todd Lawrence Landsman , Tyler Joseph Touchet , Elizabeth L. Cosgriff-Hernandez , Thomas S. Wilson
Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
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公开(公告)号：US09670308B2
公开(公告)日：2017-06-06
申请号：US13797727
申请日：2013-03-12
Inventor： Pooja Singhal , Thomas S. Wilson , Elizabeth Cosgriff-Hernandez , Duncan J. Maitland
IPC: A61B17/08 , C08G18/66 , A61B17/00 , C08G63/00 , C08G63/685 , C08G71/04 , C08J9/00 , C08G18/10 , C08G18/08 , C08G18/16 , C08G18/73 , C08G101/00
CPC classification number: C08G18/6622 , A61B17/0057 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , C08G18/10 , C08G18/14 , C08G18/165 , C08G18/73 , C08G63/00 , C08G63/6852 , C08G71/04 , C08G2101/005 , C08G2101/0083 , C08G2230/00 , C08G2280/00 , C08J9/00 , C08J2375/06
Abstract: A device, system and method for treatment of an opening in vascular and/or septal walls including patent foramen ovale. The device has wings/stops on either end, an axis core covered in a shape memory foam and is deliverable via a catheter to the affected opening, finally expanding into a vascular or septal opening where it is held in place by the expandable shape memory stops or wings.
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公开(公告)号：US20160270961A1
公开(公告)日：2016-09-22
申请号：US14661215
申请日：2015-03-18
Inventor： Duncan J. Maitland , Todd Lawrence Landsman , Tyler Joseph Touchet , Elizabeth L. Cosgriff-Hernandez , Thomas S. Wilson
CPC classification number: A61L15/18 , A61F13/00017 , A61L15/26 , A61L15/425 , A61L15/46 , A61L24/0015 , A61L24/0036 , A61L24/0094 , A61L2300/106 , A61L2300/404 , A61L2400/16 , C08L75/04
Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
Abstract translation: 一种实施方案包括伤口敷料，其包括：具有第一和第二状态的形状记忆聚合物（SMP）泡沫，包括开孔; 和包含在细胞内的水凝胶（HG）; 其中（a）在第一位置，包括所述SMP泡沫和HG的复合物构造成位于所述SMP泡沫处于第一状态的出血组织附近; （b）在第二位置，当SMP泡沫在37℃下塑化时，将复合材料构造成相对于出血组织膨胀至第二状态，将SMP泡沫的玻璃化转变温度（Tg）降至25℃以下 在此描述其它实施例。
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Patent Agency Ranking
公开(公告)号：US20140277057A1
公开(公告)日：2014-09-18
申请号：US13798740
申请日：2013-03-13
Applicant: Jonathan Hartman , LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Jason M. Ortega , William J. Benett , Ward Small , Thomas S. Wilson , Duncan J. Maitland , Jonathan Hartman
IPC: A61M29/00
CPC classification number: A61B17/12113 , A61B17/12022 , A61B17/12031 , A61B17/12181 , A61B2017/0061 , A61B2017/00871 , A61B2017/12077
Abstract: A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.
Abstract translation: 一种用于治疗血管或静脉中的动脉瘤的系统，其中所述动脉瘤具有圆顶，内部和颈部。 该系统包括在圆顶和颈部之间的动脉瘤内部的形状记忆聚合物泡沫。 形状记忆聚合物泡沫具有包括具有第一孔径的第一多个孔和具有第二孔径的第二多个孔的孔。 第二孔径大于所述第一孔径。 第一个多孔的孔位于动脉瘤的颈部。 孔的第二个多重性位于动脉瘤的圆顶。
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公开(公告)号：US20250143710A1
公开(公告)日：2025-05-08
申请号：US19017931
申请日：2025-01-13
Inventor： Thomas S. Wilson , Ward Small, IV , William J. Benett , Jason M. Ortega , Duncan J. Maitland , Jonathan Hartman
Abstract: An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.
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公开(公告)号：US12220491B2
公开(公告)日：2025-02-11
申请号：US18586901
申请日：2024-02-26
Inventor： Duncan J. Maitland , Todd Lawrence Landsman , Tyler Joseph Touchet , Elizabeth L. Cosgriff-Hernandez , Thomas S. Wilson
Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
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公开(公告)号：US20240260967A1
公开(公告)日：2024-08-08
申请号：US18618018
申请日：2024-03-27
Inventor： Duncan J. Maitland , Todd L. Landsman , Jennifer N. Rodriguez , Anthony J. Boyle , Alan C. Glowczwski , Mark A. Wierzbicki
CPC classification number: A61B17/1219 , A61B17/12109 , A61B17/1215 , A61B17/12172 , A61B2017/00526 , A61B2017/00871 , A61B2017/00898 , A61B2017/12063
Abstract: An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit.
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公开(公告)号：US11958220B2
公开(公告)日：2024-04-16
申请号：US17977345
申请日：2022-10-31
Inventor： Jennifer N. Rodriguez , Duncan J. Maitland , Thomas S. Wilson
IPC: B29C44/56 , A61L31/06 , A61L31/14 , B29C65/00 , B29K75/00 , B29K105/04 , B32B5/18 , B32B5/32 , C08G18/32 , C08G18/73 , C08G101/00 , C08J9/38 , C08L75/04
CPC classification number: B29C44/5663 , A61L31/06 , A61L31/146 , B29C66/02242 , B32B5/18 , B32B5/32 , C08G18/3228 , C08G18/3278 , C08G18/3284 , C08G18/73 , C08J9/38 , C08L75/04 , A61L2400/16 , B29C2793/0045 , B29K2075/00 , B29K2105/046 , B29K2995/0093 , B32B2266/0278 , B32B2266/08 , B32B2535/00 , C08G2101/00 , C08J2205/052 , C08J2207/10 , C08J2375/04 , C08L2201/12 , C08L2203/14 , A61L31/06 , C08L75/04
Abstract: Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
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