利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

23 条记录 (耗时 0.029 秒)

    FLUORESCENT CYCLIC PEPTIDES, PREPARATION METHOD THEREOF AND USE OF THESE PEPTIDES FOR MEASURING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME
    11.
    发明申请
    FLUORESCENT CYCLIC PEPTIDES, PREPARATION METHOD THEREOF AND USE OF THESE PEPTIDES FOR MEASURING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME 有权
    荧光素环肽，其制备方法及其用途，用于测定蛋白酶的酶活性

    公开(公告)号：US20110256567A1

    公开(公告)日：2011-10-20

    申请号：US12737082

    申请日：2009-06-10

    申请人： Thomas Berthelot ,  Gérard Deleris

    发明人： Thomas Berthelot ,  Gérard Deleris

    IPC分类号： C12Q1/37 ,  C07K1/107 ,  C07K7/64

    CPC分类号： C12Q1/37 ,  C07K7/64 ,  G01N2333/95 ,  G01N2333/96494

    摘要： The invention pertains to a cyclic peptide comprising the following sequence: -S1-X1-S2-X2- wherein S1 is a first target peptide sequence of a protease enzyme E1, S2 is a second target peptide sequence of a protease enzyme E2, S1 and S2 possibly being the same or different, said first peptide sequence S1 and said second peptide sequence S2 comprising 4 to 14 amino acids, E1 and E2 possibly corresponding to the same protease enzyme or to two different protease enzymes, X1 is a probe carrying a fluorescent donor group and X2 is a probe carrying a fluorescent or non-fluorescent acceptor group. Application of these peptides to determination of the activity of protease enzymes.

    摘要翻译： 本发明涉及包含以下序列的环肽：-S1-X1-S2-X2-，其中S1是蛋白酶E1的第一个靶肽序列，S2是蛋白酶E2的第二个靶肽序列，S1和 S2可能相同或不同，所述第一肽序列S1和包含4至14个氨基酸的第二肽序列S2，E1和E2可能对应于相同的蛋白酶或两种不同的蛋白酶，X1是携带荧光 供体组，X2是携带荧光或非荧光受体组的探针。 应用这些肽来测定蛋白酶的活性。

    Chemical modification process for a deep polymeric matrix
    12.
    发明授权
    Chemical modification process for a deep polymeric matrix 有权
    深层聚合物基体的化学修饰方法

    公开(公告)号：US09453284B2

    公开(公告)日：2016-09-27

    申请号：US12772122

    申请日：2010-04-30

    申请人： Thomas Berthelot ,  Cécile Baudin

    发明人： Thomas Berthelot ,  Cécile Baudin

    IPC分类号： B05D3/06 ,  C23C18/16 ,  C08J3/28 ,  C08J7/12 ,  C08J7/16 ,  C23C18/18 ,  C23C18/20

    CPC分类号： C23C18/1601 ,  C08J3/28 ,  C08J7/123 ,  C08J7/16 ,  C08J2323/26 ,  C08J2327/18 ,  C23C18/18 ,  C23C18/1844 ,  C23C18/1893 ,  C23C18/2086 ,  Y10T428/1352

    摘要： The present invention relates to a process for chemically modifying, within its thickness, a polymer matrix chosen from matrices made of fluoropolymers and matrices made of aliphatic polymers, said process comprising at least one step consisting in irradiating said matrix with UV light having a wavelength of less than 300 nm in order to generate, within the thickness of said matrix, zones that have short polymer chains, formed by scission of the existing chains during the passage of the UV radiation and that have free radicals denoted hereinbelow as “activated zones”. The present invention also relates to the polymer matrix capable of being chemically modified by such a process.

    摘要翻译： 本发明涉及一种在其厚度内化学改性选自由含氟聚合物和由脂族聚合物制成的基质的基体的聚合物基体的方法，所述方法包括至少一个步骤，该步骤包括用波长为 小于300nm，以便在所述基质的厚度内产生具有短聚合物链的区域，其通过在UV辐射通过过程中现有链的断裂而形成，并且在下文中具有自由基作为“活化区”。 本发明还涉及能够通过这种方法化学改性的聚合物基质。

    PROCESS FOR PREPARING A METALLIZED SUBSTRATE, SAID SUBSTRATE AND USES THEREOF
    16.
    发明申请
    PROCESS FOR PREPARING A METALLIZED SUBSTRATE, SAID SUBSTRATE AND USES THEREOF 审中-公开
    用于制备金属化基板，合金基板及其用途的方法

    公开(公告)号：US20100310800A1

    公开(公告)日：2010-12-09

    申请号：US12772126

    申请日：2010-04-30

    申请人： Thomas Berthelot ,  Pascal Viel ,  Alexandre Garcia ,  Sébastien Roussel

    发明人： Thomas Berthelot ,  Pascal Viel ,  Alexandre Garcia ,  Sébastien Roussel

    IPC分类号： B32B1/02 ,  C25D11/18 ,  C08F8/42 ,  C08J3/28

    CPC分类号： C23C18/1601 ,  C08J3/28 ,  C08J7/123 ,  C08J7/16 ,  C08J2323/26 ,  C08J2327/18 ,  C23C18/18 ,  C23C18/1844 ,  C23C18/1893 ,  C23C18/2086 ,  Y10T428/1352

    摘要： The present invention relates to a process for preparing a metallized substrate, comprising the steps consisting in: grafting onto said substrate a compound of polymer type optionally bearing a group that is capable of chelating at least one metal ion; placing said compound of polymer type that is capable of chelating at least one metal ion in contact with at least one metal ion, and subjecting the compound of polymer type to conditions for reducing said chelated metal ion(s), and repeating the chelation/reduction steps until a metallized substrate is obtained. The present invention also relates to the substrate obtained during this process and to the uses thereof.

    摘要翻译： 本发明涉及一种制备金属化基材的方法，包括以下步骤：将所述聚合物类型的化合物接枝到所述基材上，所述聚合物类型的化合物任选地具有能够螯合至少一种金属离子的基团; 将能够螯合至少一种金属离子的聚合物类型的化合物与至少一种金属离子接触，并使聚合物类型的化合物进行还原所述螯合金属离子的条件，并重复螯合/还原 步骤直到获得金属化基底。 本发明还涉及在该方法中获得的基材及其用途。

    CHEMICAL MODIFICATION PROCESS FOR A DEEP POLYMERIC MATRIX
    18.
    发明申请
    CHEMICAL MODIFICATION PROCESS FOR A DEEP POLYMERIC MATRIX 有权
    一种深层聚合物基质的化学改性方法

    公开(公告)号：US20100311857A1

    公开(公告)日：2010-12-09

    申请号：US12772122

    申请日：2010-04-30

    申请人： Thomas Berthelot ,  Cécile Baudin

    发明人： Thomas Berthelot ,  Cécile Baudin

    IPC分类号： C08F2/46 ,  C08F14/22 ,  C08F10/02 ,  C08F22/10

    CPC分类号： C23C18/1601 ,  C08J3/28 ,  C08J7/123 ,  C08J7/16 ,  C08J2323/26 ,  C08J2327/18 ,  C23C18/18 ,  C23C18/1844 ,  C23C18/1893 ,  C23C18/2086 ,  Y10T428/1352

    摘要： The present invention relates to a process for chemically modifying, within its thickness, a polymer matrix chosen from matrices made of fluoropolymers and matrices made of aliphatic polymers, said process comprising at least one step consisting in irradiating said matrix with UV light having a wavelength of less than 300 nm in order to generate, within the thickness of said matrix, zones that have short polymer chains, formed by scission of the existing chains during the passage of the UV radiation and that have free radicals denoted hereinbelow as “activated zones”. The present invention also relates to the polymer matrix capable of being chemically modified by such a process.

    摘要翻译： 本发明涉及一种在其厚度内化学改性选自由含氟聚合物和由脂族聚合物制成的基质的基体的聚合物基体的方法，所述方法包括至少一个步骤，该步骤包括用波长为 小于300nm，以便在所述基质的厚度内产生具有短聚合物链的区域，其通过在UV辐射通过过程中现有链的断裂而形成，并且在下文中具有自由基作为“活化区”。 本发明还涉及能够通过这种方法化学改性的聚合物基质。