-
公开(公告)号:US5698574A
公开(公告)日:1997-12-16
申请号:US503183
申请日:1995-07-17
申请人: Bernd Riedl , Dieter Habich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus Dieter Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
发明人: Bernd Riedl , Dieter Habich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus Dieter Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
IPC分类号: C07D333/38 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/426 , A61K31/44 , A61K31/655 , A61P31/04 , C07D263/32 , C07D263/48 , C07D277/20 , C07D277/44 , C07D333/66 , C07D413/04 , C07D413/08 , C07D413/14 , C07D417/04 , C07D417/14 , C07D413/00
CPC分类号: C07D413/04 , C07D263/48 , C07D413/08 , C07D413/14 , C07D417/04
摘要: The present invention relates to 5-membered heteroaryl-oxazolidinones, to processes for their preparation and to their use as medicaments, in particular as antibacterial medicaments.
摘要翻译: 本发明涉及5元杂芳基 - 恶唑烷酮,其制备方法和用作药物,特别是抗菌药物。
-
公开(公告)号:US20120178780A1
公开(公告)日:2012-07-12
申请号:US13424111
申请日:2012-03-19
申请人: Jill E. WOOD , Hanno Wild , Daniel H. Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger A. Smith , Cheri Blum
发明人: Jill E. WOOD , Hanno Wild , Daniel H. Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger A. Smith , Cheri Blum
IPC分类号: A61K31/381 , A61K31/4155 , A61K31/437 , A61K31/34 , A61K31/40 , A61K31/404 , A61K31/427 , A61K31/4025 , C07D333/38 , C07D417/12 , C07D409/12 , C07D307/68 , C07D207/34 , C07D471/04 , A61P35/00 , A61K31/433
CPC分类号: C07D207/34 , C07D307/68 , C07D333/38 , C07D409/12 , C07D417/12 , C07D471/04
摘要: Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
摘要翻译: 治疗由raf激酶介导的肿瘤与取代的脲化合物及其化合物本身的方法。
-
公开(公告)号:US20100093803A1
公开(公告)日:2010-04-15
申请号:US12447207
申请日:2007-10-16
申请人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Hanno Wild , Peter Kolkhof , Hartmut Beck , Mario Jeske
发明人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Hanno Wild , Peter Kolkhof , Hartmut Beck , Mario Jeske
IPC分类号: A61K31/444 , C07D401/14
CPC分类号: C07D401/14
摘要: The present application relates to novel substituted dipyridyldihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
摘要翻译: 本申请涉及新的取代二吡啶基二氢吡喃酮衍生物,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管和血液疾病和肾脏的药物的用途 疾病和促进伤口愈合。
-
14.Substituted 2,5-diamidoindoles as ECE inhibitors for the treatment of cardiovascular diseases 失效
标题翻译: 取代的2,5-二氨基吲哚作为治疗心血管疾病的ECE抑制剂公开(公告)号:US07045544B2
公开(公告)日:2006-05-16
申请号:US10490821
申请日:2002-09-16
申请人: Jens-Kerim Ergüden , Thomas Krahn , Christian Schröder , Johannes-Peter Stasch , Stefan Weigand , Hanno Wild , Michael Brands
发明人: Jens-Kerim Ergüden , Thomas Krahn , Christian Schröder , Johannes-Peter Stasch , Stefan Weigand , Hanno Wild , Michael Brands
IPC分类号: A61K31/404 , A61K31/4439 , A61K31/433 , C07D209/40 , C07D405/12
CPC分类号: C07D401/12 , C07D209/42
摘要: The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals
摘要翻译: 本发明涉及式(I)化合物,其制备方法及其用作药物治疗人和/或动物疾病的方法
-
15.hIL-4 mutant proteins used as antagonists or partial agonists of human interleukin 4 失效
标题翻译: hIL-4突变蛋白用作人白细胞介素4的拮抗剂或部分激动剂公开(公告)号:US6130318A
公开(公告)日:2000-10-10
申请号:US765012
申请日:1996-12-19
申请人: Hanno Wild , Rudolf Hanko , Michael Dorschug , Hans-Dietrich Horlein , Jurgen Beunink , Heiner Apeler , Hermann Wehlmann , Walter Sebald
发明人: Hanno Wild , Rudolf Hanko , Michael Dorschug , Hans-Dietrich Horlein , Jurgen Beunink , Heiner Apeler , Hermann Wehlmann , Walter Sebald
CPC分类号: C07K14/5406 , A61K38/00
摘要: The present invention relates to novel hIL-4 mutant proteins, to processes for preparing them, and to their use as medicaments, in particular in overshooting, falsely regulated immune reactions and autoimmune diseases.
摘要翻译: PCT No.PCT / EP95 / 02358 371 1996年12月19日第 102(e)日期1996年12月19日PCT Filed 1995年6月19日PCT公布。 出版物WO96 / 01274 日本1996年1月18日本发明涉及新型hIL-4突变蛋白,其制备方法及其作为药物的用途,特别涉及过量,错误调节的免疫反应和自身免疫性疾病。
-
公开(公告)号:US08389520B2
公开(公告)日:2013-03-05
申请号:US12447192
申请日:2007-10-12
申请人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Jörg Keldenich , Metin Akbaba , Mario Jeske
发明人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Jörg Keldenich , Metin Akbaba , Mario Jeske
IPC分类号: A61K31/5377 , C07D413/14
CPC分类号: C07D487/04 , A61K31/427 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K45/06 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要: The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
-
17.SUBSTITUTED DIHYDROPYRAZOLONES AND USE THEREOF AS HIF-PROLYL-4 -HYDROXYLASE INHIBITORS 有权
标题翻译: 取代的二氢吡咯烷酮及其作为HIF-PROLYL-4-羟基酶抑制剂的用途公开(公告)号:US20120264704A1
公开(公告)日:2012-10-18
申请号:US12447201
申请日:2007-10-26
申请人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
发明人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
IPC分类号: A61K31/506 , C07D417/14 , A61K31/4439 , C07D413/14 , A61K31/5377 , A61K31/517 , A61K31/501 , A61K31/4709 , A61K31/497 , A61K31/55 , A61P7/10 , A61K31/616 , A61P31/04 , A61P35/00 , A61K31/7048 , A61P9/00 , A61P7/06 , A61P13/12 , C07D471/04 , A61K31/498 , A61K31/714 , C07D401/14
CPC分类号: C07D417/14 , C07D401/14
摘要: The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
摘要翻译: 本申请涉及新型取代的二氢吡喃酮衍生物,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管和血液疾病和肾脏的药物的用途 疾病和促进伤口愈合。
-
18.Use of substituted 2,5-diamidoindoles for the treatment of urological diseases 审中-公开
标题翻译: 取代的2,5-二酰氨基吲哚用于治疗泌尿系疾病公开(公告)号:US20060183753A1
公开(公告)日:2006-08-17
申请号:US10539203
申请日:2003-12-06
申请人: Jens Erguden , Thomas Krahn , Christian Schroder , Johannes Stasch , Stefan Weigand , Hanno Wild , Michael Brands , Stehan Siegel , Dirk Heimbach , Jorg Keldenich , Masaomi Tajimi , Hiroko Takagi
发明人: Jens Erguden , Thomas Krahn , Christian Schroder , Johannes Stasch , Stefan Weigand , Hanno Wild , Michael Brands , Stehan Siegel , Dirk Heimbach , Jorg Keldenich , Masaomi Tajimi , Hiroko Takagi
IPC分类号: A61K31/506 , A61K31/4439 , A61K31/405
CPC分类号: A61K31/433 , A61K31/404 , A61K31/405 , A61K31/4439
摘要: The present invention relates to the use of 2,5-diamidoindole derivatives for the preparation of medicaments for treating urological disorders in humans and/or animals.RCK 41-Foreign Countries
摘要翻译: 本发明涉及2,5-二酰氨基吲哚衍生物在制备用于治疗人和/或动物泌尿系统疾病的药物中的用途。
-
19.Substituted 2 5-diamidoindoles as ece inhibitors for the treatment of cardiovascular diseases 失效
标题翻译: 取代的2,5-二氨基吲哚作为治疗心血管疾病的ece抑制剂公开(公告)号:US20050038101A1
公开(公告)日:2005-02-17
申请号:US10490821
申请日:2002-09-16
申请人: Jens-Kerim Erguden , Thomas Krahn , Christian Schroder , Johannes-Peter Stasch , Stefan Weigand , Hanno Wild , Michael Brands
发明人: Jens-Kerim Erguden , Thomas Krahn , Christian Schroder , Johannes-Peter Stasch , Stefan Weigand , Hanno Wild , Michael Brands
IPC分类号: A61K31/404 , A61K31/427 , A61K31/433 , A61K31/4439 , A61P9/00 , A61P9/04 , A61P9/10 , C07D209/42 , C07D401/12 , C07D405/12 , C07D409/06 , C07D417/06 , C07D417/12 , A61K31/405 , C07D45/02
CPC分类号: C07D401/12 , C07D209/42
摘要: The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals.
摘要翻译: 本发明涉及式(I)化合物,其制备方法,以及其用于治疗人和/或动物疾病的药物。
-
公开(公告)号:US5869659A
公开(公告)日:1999-02-09
申请号:US785145
申请日:1997-01-13
申请人: Andreas Stolle , Dieter Habich , Bernd Riedl , Martin Ruppelt , Stephen Bartel , Walter Guarnieri , Hanno Wild , Rainer Endermann , Hein-Peter Kroll
发明人: Andreas Stolle , Dieter Habich , Bernd Riedl , Martin Ruppelt , Stephen Bartel , Walter Guarnieri , Hanno Wild , Rainer Endermann , Hein-Peter Kroll
IPC分类号: C07D471/04 , A61K31/42 , A61K31/425 , A61K31/435 , A61K31/66 , A61K31/675 , A61P31/00 , A61P31/04 , C07D263/58 , C07D291/08 , C07D413/04 , C07D417/04 , C07D417/14 , C07D498/04 , C07D513/04 , C07F9/6539 , C07F9/6558 , C07F9/6561 , C07F9/6581 , C07F9/6584 , C07D413/00 , C07D239/00 , C07D257/08 , C07D487/00
CPC分类号: C07D513/04 , C07F9/6561 , Y02P20/55
摘要: The present invention relates to heteroatom-containing cyclopentanopyridyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
摘要翻译: 本发明涉及含杂原子的环戊基吡啶基 - 恶唑烷酮,其制备方法及其作为药物的用途,特别是抗菌药物。
-
-
-
-
-
-
-
-
-