公开(公告)号：US11963932B2

公开(公告)日：2024-04-23

申请号：US16695056

申请日：2019-11-25

Applicant: ICU Medical, Inc.

Inventor： John M. Seifert ,  Thomas F. Fangrow

IPC: A61J1/20 ,  A61J1/14 ,  A61J1/22

CPC classification number: A61J1/2048 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/201 ,  A61J1/2065 ,  A61J1/2072 ,  A61J1/2075 ,  A61J1/2079 ,  A61J1/2082 ,  A61J1/2089 ,  A61J1/2096 ,  A61J1/2055 ,  A61J1/2086 ,  A61J1/22 ,  A61J2200/10 ,  A61J2200/76 ,  Y10T29/49826 ,  Y10T29/49885 ,  Y10T137/0402

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial. In order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

公开(公告)号：US11938094B2

公开(公告)日：2024-03-26

申请号：US17716107

申请日：2022-04-08

Applicant: CareFusion 303, Inc.

Inventor： Todd Oda ,  Tomas Frausto ,  Dereck Ferdaws

IPC: A61J3/00 ,  A61J1/20

CPC classification number: A61J3/002 ,  A61J1/201 ,  A61J1/2058 ,  A61J1/2089

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle.

公开(公告)号：US20240058217A1

公开(公告)日：2024-02-22

申请号：US18267365

申请日：2021-12-17

Applicant: Jeff Price ,  Koska Family Limited

Inventor： Jeff Price ,  Marc Andrew Koska

IPC: A61J1/14 ,  A61J1/20 ,  A61J1/06

CPC classification number: A61J1/1406 ,  A61J1/1481 ,  A61J1/2096 ,  A61J1/2089 ,  A61J1/201 ,  A61J1/065

Abstract: A pre-filled blow-fill-seal (BFS) vial can have a fluid seal at one end thereof that can be breached by a piercing element within a connector when a neck of the BFS vial is fully inserted into the connector. The piercing element can comprise or define one or more fluid conduits that allow fluid to flow from an interior of the BFS vial to an outlet port of the connector, thereby allowing the contents to be dispensed from the BFS vial. The connector can facilitate coupling of the BFS vial for subsequent administration of the contents therein to a patient. For example, the outlet port of the connector can be coupled to an administration assembly, such as a syringe, nozzle, intravenous (IV) therapy device, or another device.

公开(公告)号：US20240050316A1

公开(公告)日：2024-02-15

申请号：US18258058

申请日：2021-12-17

Applicant: Congruence Medical Solutions, LLC

Inventor： Gautam Nithyanand Shetty

IPC: A61J1/20 ,  A61J1/14

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2048 ,  A61J1/1406

Abstract: Methods for administration of injectable fluids and a vial adapter for use with an injector and a vial containing the fluid. The adapter includes a vial retainer, a spacing disc, and a spacing arm. The vial retainer is sized to receive at least a portion of the vial, the stopper and the stopper retainer of the vial. The spacing disc includes a needle insertion port, and is spaced a predetermined distance from the vial retainer by the spacing arm. A distance an injector needle inserted through the port may extend through the stopper is limited by contact of the injector with the spacing disc.

公开(公告)号：US20240024199A1

公开(公告)日：2024-01-25

申请号：US18363887

申请日：2023-08-02

Applicant: Enable Injections, Inc.

Inventor： Dylan Bourelle ,  Matthew Huddleston ,  Joetta Renee Palmer ,  David Stefanchik

IPC: A61J1/20 ,  A61J1/14 ,  A61J1/16 ,  A61J1/18 ,  B01F31/20 ,  A61M5/20

CPC classification number: A61J1/2062 ,  A61J1/201 ,  A61J1/2037 ,  A61J1/2048 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/1406 ,  A61J1/16 ,  A61J1/18 ,  A61J1/2096 ,  B01F31/265 ,  A61M5/2066 ,  A61J1/20 ,  A61J2200/76 ,  A61J2205/20 ,  B01F2215/0454 ,  B01F2101/2202

Abstract: An automated transfer and mixing device receives an injection device, a lyophilized drug vial and a diluent vial and transfers diluent from the diluent vial to the lyophilized drug vial and shakes or vibrates the lyophilized drug vial to reconstitute the drug. The device then transfers the reconstituted drug from the lyophilized drug vial to the injection device.

公开(公告)号：US20240016702A1

公开(公告)日：2024-01-18

申请号：US18475661

申请日：2023-09-27

Applicant: CRISI Medical Systems, Inc.

Inventor： Walter John Bochenko

IPC: A61J1/20 ,  B65B3/00

CPC classification number: A61J1/2096 ,  B65B3/003 ,  A61J1/201 ,  A61J2205/10 ,  A61J2205/30 ,  A61J2205/60 ,  A61J2205/20 ,  A61J1/1418

Abstract: A medication and identification information transfer system is provided that includes a primary medication container, a secondary medication container, a secondary container label and a medication information transfer apparatus. The medication information transfer apparatus, when coupled to the primary medication container, can transfer information indicative of the contents of the primary medication container to a medication delivery device such as an intelligent injection site. The medication information transfer apparatus has a shape and size enabling it to be connected to an adapter for removal of medication from the primary medication container which enables transfer of the medication to a secondary container while simultaneously transferring information about the medication in the primary medication container to the injection site. In some implementations, the medication injection site can be placed on a fluid delivery line for infusion into a patient. Related apparatus, systems, methods and kits are also disclosed.

公开(公告)号：US20230404852A1

公开(公告)日：2023-12-21

申请号：US18036001

申请日：2021-11-09

Applicant: Becton, Dickinson and Company

Inventor： Paul Paia Marici

IPC: A61J1/20

CPC classification number: A61J1/2072 ,  A61J1/2096 ,  A61J1/201 ,  A61J1/2086

Abstract: A vial adapter includes a body having a component connection interface and a vial connection interface, a pressure equalization assembly including an equalization housing, an expandable member, and a valve member, with the equalization housing and the expandable member defining a space configured to expand from a first volume to a second volume larger than the first volume, and a piercing member. The equalization housing defining an equalization opening in fluid communication with the space and an intake opening in fluid communication with the valve member, with the valve member configured to allow air into the space from the intake opening and prevent air from the space to exit the intake opening. The equalization housing defines a channel in fluid communication with the equalization opening and the valve member.

公开(公告)号：US20230390160A1

公开(公告)日：2023-12-07

申请号：US18234432

申请日：2023-08-16

Applicant: RVL Skincare, PC

Inventor： Rita V. Linkner ,  Marc-Alan Levine

IPC: A61J1/20 ,  A61K38/48

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61K38/4893 ,  A61J1/2048 ,  A61J1/2079

Abstract: A vial adapter for reconstituting a drug and drawing a drug from a vial. The vial adapter includes a passageway for passage of a diluent into the vial to mix with and reconstitute the drug and a chamber containing the reconstituted drug drawn from the vial. A vacuum is applied through the adapter to draw the reconstituted drug from the vial. The reconstituted drug can be accessed in one or two ways, either via a luer locked syringe or via a needled syringe.

公开(公告)号：US11833279B2

公开(公告)日：2023-12-05

申请号：US17837090

申请日：2022-06-10

Applicant: Astaria Global, LLC

Inventor： David J. Lutz ,  William J. Cramer ,  Michael D. Duvall ,  Robert S. Shoemaker

IPC: A61M1/02 ,  B01L3/00 ,  A61K35/16 ,  A61J1/20 ,  A61K38/17 ,  A61K38/57

CPC classification number: A61M1/029 ,  A61J1/201 ,  A61J1/2062 ,  A61J1/2082 ,  A61J1/2096 ,  A61K35/16 ,  A61K38/1722 ,  A61K38/57 ,  B01L3/5021 ,  B01L3/50825 ,  A61M2202/0417 ,  B01L2300/0832 ,  B01L2400/0409 ,  B01L2400/0478

Abstract: A method includes: depositing whole blood into at least one separator tube; subjecting the at least one separator tube to a first centrifugal force to cause a combination of the first centrifugal force and separator gel within each separator tube of the at least one separator tube to separate plasma of the whole blood from red and white blood cells of the whole blood within the at least one separator tube, wherein the plasma includes α2M molecules; transferring one or more portions of the plasma from within the at least one separator tube and into at least one isolator; and subjecting the at least one isolator to a second centrifugal force to cause a combination of the second centrifugal force and a filter within each isolator of the at least one isolator to isolate the α2M molecules from other components of the plasma within the at least one isolator.

公开(公告)号：US11801199B2

公开(公告)日：2023-10-31

申请号：US17973877

申请日：2022-10-26

Applicant: Bristol-Myers Squibb Company

Inventor： Martin John McLoughlin ,  Chester Larrow ,  Mariano Mumpower

IPC: A61J1/20 ,  A61M5/14 ,  A61M5/142

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2058 ,  A61J1/2075 ,  A61M5/1407 ,  A61M5/1408 ,  A61M5/1409 ,  A61M5/1413 ,  A61M5/14248 ,  A61J1/2068

Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.