公开(公告)号：US20150359698A1

公开(公告)日：2015-12-17

申请号：US14628663

申请日：2015-02-23

Applicant: Worcester Polytechnic Institute

Inventor： Marko Popovic ,  Cagdas Onal ,  Daniil Effraimidis ,  Brian Jennings ,  Gregory D. McCarthy ,  Nicholas Corso

IPC: A61H3/00 ,  F15B15/10

CPC classification number: A61H3/00 ,  A61F2/68 ,  A61F2002/5066 ,  A61F2002/704 ,  A61F2002/74 ,  A61F2002/745 ,  A61F2002/748 ,  A61F2002/762 ,  A61F2002/7635 ,  A61H1/024 ,  A61H1/0277 ,  A61H1/0281 ,  A61H2201/1238 ,  A61H2201/1614 ,  A61H2201/1635 ,  A61H2201/164 ,  A61H2201/165 ,  A61H2201/5007 ,  A61H2201/5058 ,  A61H2201/5071 ,  A61H2201/5087 ,  F15B15/103

Abstract: Actuators and methods of use are provided. An actuator may comprise an inner member made from an elastic material and defining a compartment for receiving an actuating fluid, the inner member being moveable in a longitudinal direction from a relaxed state to an expanded state by introducing an actuating fluid into the inner member; and an outer member made from an inelastic material and being disposed around the elastic inner member to control expansion of the elastic inner member in a radial direction, the outer member being moveable from a folded relaxed configuration to an unfolded extended configuration as the inner member moves from the relaxed state to the expanded state, wherein the movement of the actuator between the relaxed state and the expanded state causes a movement of a structure to which the actuator is attached.

Abstract translation: 提供执行器和使用方法。 致动器可以包括由弹性材料制成并限定用于接收致动流体的隔室的内部构件，所述内部构件可以通过将致动流体引入到内部构件中而在纵向方向上从松弛状态向膨胀状态移动; 以及由非弹性材料制成并且设置在弹性内部构件周围的外部构件，以控制弹性内部构件沿径向的膨胀，外部构件可随着内部构件移动而从折叠的松弛构型移动到展开的延伸构型 从松弛状态到膨胀状态，其中致动器在松弛状态和膨胀状态之间的运动引起致动器附接到的结构的移动。

公开(公告)号：US20150310727A1

公开(公告)日：2015-10-29

申请号：US14694025

申请日：2015-04-23

Applicant: Worcester Polytechnic Institute

Inventor： James A. Beaulieu, JR. ,  Natasha Bonina ,  Lauren E. Lewis ,  Phyo Thinzar

IPC: G08B25/01

CPC classification number: G08B25/016

Abstract: A personal protection device carried or worn by a user has a simple actuator button and transmitter operable within a mesh network covering a monitored environment such as a college campus or industrial park transmits an exigent assistance call to a first responder such as security or DPS (Department of Public Safety) personnel for urgent response. The system for deploying and monitoring the personal protection devices distributes or otherwise transfers possession of an actuator device to a user, such that the actuator device is adapted for wearing or disposing on the user in anticipation of a sudden exigent situation. A distribution repository associates the actuator device with the user, in which the association is temporary for subsequent association with a second user to provide efficient reuse as devices are exchanged or no longer needed.

Abstract translation: 用户携带或佩戴的个人保护装置具有简单的执行器按钮和发送器，其可在覆盖受监控的环境的网状网络（例如大学校园或工业园区）内操作，将紧急援助呼叫传送到诸如安全性或DPS的第一响应者 的公共安全）人员进行紧急反应。 用于部署和监视个人保护装置的系统分配或以其他方式将执行器装置的所有权转移给用户，使得致动器装置适于在预期突然的紧急情况下佩戴或布置在使用者身上。 分发存储库将致动器设备与用户相关联，其中关联是临时的，用于随后与第二用户的关联，以在设备交换或不再需要时提供有效的重用。

公开(公告)号：US20150289775A1

公开(公告)日：2015-10-15

申请号：US14688465

申请日：2015-04-16

Applicant: Worcester Polytechnic Institute

Inventor： Ki Chon ,  Justin Bales ,  Bersain A. Reyes ,  Hugo F. Posada-Quintero

IPC: A61B5/0408 ,  B29C70/72 ,  B29C70/88 ,  A61B5/0478

CPC classification number: B29C70/885 ,  A61B5/0424 ,  A61B2560/0412 ,  A61B2562/0215 ,  A61B2562/125 ,  A61B2562/164 ,  A61B2562/18 ,  B29C39/10 ,  B29L2031/34 ,  B29L2031/753 ,  Y10T29/49117

Abstract: An epidermal electrode operable independently of the ambient environment, such as the presence of water, sweat, or dry conditions, and achieve a suitable impedance with the epidermal surface for transmitting electrical signals indicative of bodily physiological process such as ECG signals for heart monitoring. The hydrophobic surface mountable electrode including a flexible, conductive substrate of PDMS (Polydimethylsiloxane) with dispersed carbon black and having a substantially planar sensing area adapted for communication with an electrically sensitive surface such as a patient's skin, and an embedded conductor encapsulated in the substrate for connection to a monitor circuit, the terminal having electrical continuity with the planar sensing area.

Abstract translation: 可以独立于周围环境操作的表皮电极，例如存在水，汗水或干燥条件，并且与表皮表面实现适当的阻抗，用于传输指示身体生理过程的电信号，例如用于心脏监测的ECG信号。 所述疏水性表面可安装电极包括具有分散的炭黑并且具有适于与电敏感表面（例如患者皮肤）相通的基本平坦的感测区域的柔性导电性PDMS基质（聚二甲基硅氧烷），以及封装在所述衬底中的嵌入式导体 连接到监视器电路，该终端具有与平面检测区域的电连续性。

公开(公告)号：US20150168403A1

公开(公告)日：2015-06-18

申请号：US14575205

申请日：2014-12-18

Applicant: Worcester Polytechnic Institute

Inventor： Reeta Prusty Rao

IPC: G01N33/569

CPC classification number: G01N33/56961 ,  C12Q1/18 ,  G01N33/6872 ,  G01N2333/37 ,  G01N2500/04 ,  G01N2500/10

Abstract: The present invention relates to methods of screening for antifungal agents by identifying agents that bind to or otherwise inhibit indole-3-acetic acid (IAA) or that bind to or otherwise inhibit the expression or activity of a protein within the Yap family or a gene encoding a protein within the Yap family.

Abstract translation: 本发明涉及通过鉴定结合或以其它方式抑制吲哚-3-乙酸（IAA）或结合或以其它方式抑制Yap家族或基因内的蛋白质的表达或活性的试剂筛选抗真菌剂的方法 编码Yap家族内的蛋白质。

公开(公告)号：US09042367B2

公开(公告)日：2015-05-26

申请号：US14159796

申请日：2014-01-21

Applicant: The Trustees of Princeton University ,  Worcester Polytechnic Institute

Inventor： Donald Richard Brown ,  H. Vincent Poor ,  Boyang Zhang

IPC: H04W56/00

CPC classification number: H04W56/001 ,  H04W56/0035

Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for. Acoustic and radio-frequency signaling can be utilized.

Abstract translation: 提供了一种用于在多用户，无线通信系统中同步设备的相位和频率的系统和方法。 主信标信号由无线通信网络中的目的地节点发送到多个源节点。 次信标信号也在源节点之间交换。 使用主信标信号和次信标信号，节点产生用于控制源节点的局部相位和频率的局部相位和频率估计。 源节点然后基于估计的本地频率和相位在载波频率上将公共信息发送到目的地，使得所发送的信息的相位和频率被同步以促进目的地的带通信号的相干组合。 相位和频率同步可以应用于具有任何数量的源节点的无线通信系统，并且考虑到多普勒频移和移动平台的影响。 可以使用声学和射频信号。

公开(公告)号：US20150005739A1

公开(公告)日：2015-01-01

申请号：US14296109

申请日：2014-06-04

Applicant: Worcester Polytechnic Institute

Inventor： Glenn Gaudette ,  George D. Pins ,  Marsha Rolle ,  Jacques P. Guyette ,  Kevin Cornwall

IPC: A61L31/04 ,  A61L31/16 ,  C12N11/02

CPC classification number: A61L31/046 ,  A61B17/0469 ,  A61B17/06 ,  A61B17/06166 ,  A61B2017/00243 ,  A61B2017/00893 ,  A61L27/225 ,  A61L27/3826 ,  A61L27/3834 ,  A61L27/3873 ,  A61L31/16 ,  A61L2430/20 ,  C12N5/0068 ,  C12N11/02 ,  C12N2533/56

Abstract: Compositions that include microthreads are provided. The compositions can be fully or partially encased in a sleeve along at least a portion of their length and can include biological cells and, optionally, therapeutic agents. Also provided are methods for using the compositions to repair or ameliorate damaged or defective tissue, including cardiovascular tissue (e.g., the myocardium).

Abstract translation: 提供包括微丝的组合。 组合物可以沿其长度的至少一部分完全或部分地包封在套管中，并且可以包括生物细胞和任选的治疗剂。 还提供了使用组合物来修复或改善包括心血管组织（例如心肌）的损伤或缺陷组织的方法。

公开(公告)号：US20140222746A1

公开(公告)日：2014-08-07

申请号：US14167215

申请日：2014-01-29

Applicant: Worcester Polytechnic Institute

Inventor： Janice D. Gobert ,  Ryan S. Baker ,  Michael A. Sao Pedro

IPC: G06N5/02

CPC classification number: G09B19/00 ,  G06N5/022 ,  G06N5/025 ,  G06Q10/06398 ,  G09B5/00 ,  G09B5/02 ,  G09B7/02

Abstract: An assessment engine includes a definition of inquiry skills being assessed. Assessment models are used to infer skill demonstration as one or more students engage in inquiry within computerized simulations and/or microworlds. A pedagogical agent and/or help system provides real-time feedback to one or more students based on the assessment model outputs, and/or based on additional models that track one or more students developing proficiency across inquiry tasks over time. A pedagogical agent and/or help system for science inquiry tutoring responds in real-time on the basis of knowledge-engineered and data-mined assessment and/or tracking models.

Abstract translation: 评估引擎包括正在评估的查询技能的定义。 评估模型用于推测技能演示，因为一个或多个学生在计算机化模拟和/或微世界中进行查询。 教学代理和/或帮助系统基于评估模型输出，和/或基于跟踪一个或多个学生在一段时间内跨查询任务熟练度的附加模型来向一个或多个学生提供实时反馈。 用于科学咨询辅导的教学代理和/或帮助系统在知识设计和数据挖掘评估和/或跟踪模型的基础上实时响应。

公开(公告)号：US20130226845A1

公开(公告)日：2013-08-29

申请号：US13774981

申请日：2013-02-22

Applicant: WORCESTER POLYTECHNIC INSTITUTE

Inventor： Janice D. Gobert ,  Ermal Toto

IPC: G06N99/00

CPC classification number: G06N99/005 ,  G06F3/013 ,  G09B5/02 ,  G09B7/04 ,  G09B19/00 ,  G09B19/0069

Abstract: A digital instructional environment leverages an infrared eye-tracker to monitor a learner's reading and viewing of text and simulations for subject matter. The system detects out-of-order reading/viewing patterns that could lead to poor comprehension. The digital learning environment communicates with other tutorial components including simulation environments, pedagogical agents and may respond in real-time to such patterns with messages that guide learners (knowledge acquirers) to return to effective reading/viewing patterns so as to promote effective construction of mental model(s) developed during knowledge acquisition/learning.

Abstract translation: 数字教学环境利用红外眼睛跟踪器监视学习者的阅读和观看文本以及主题的模拟。 系统检测到可能导致理解差的无序阅读/查看模式。 数字学习环境与其他辅导组件（包括模拟环境，教学代理）进行通信，并且可以通过引导学习者（知识获取者）返回到有效的阅读/观看模式的消息来实时地回应这样的模式，以促进精神上的有效构建 在知识获取/学习过程中开发的模型。

公开(公告)号：US20130144180A1

公开(公告)日：2013-06-06

申请号：US13684979

申请日：2012-11-26

Applicant: Worcester Polytechnic Institute

Inventor： Ki H. Chon ,  Jinseok Lee

IPC: A61B5/046 ,  A61B5/04 ,  A61B5/0456

CPC classification number: A61B5/046 ,  A61B5/04012 ,  A61B5/0456

Abstract: Methods and systems for automatic detection of Atrial Fibrillation (AF) are disclosed. The methods and systems use time-varying coherence functions (TVCF) to detect AF. The TVCF is estimated by the multiplication of two time-varying transfer functions (TVTFs).

Abstract translation: 公开了自动检测心房颤动（AF）的方法和系统。 方法和系统使用时变相干函数（TVCF）来检测AF。 TVCF通过两个时变传递函数（TVTF）的乘法来估计。

公开(公告)号：US20250130162A1

公开(公告)日：2025-04-24

申请号：US18924362

申请日：2024-10-23

Applicant: Worcester Polytechnic Institute

Inventor： Ulkuhan Guler ,  Tuna B. Tufan ,  John A. McNeill

IPC: G01N21/31 ,  G01N33/00

Abstract: A wearable, miniaturized wireless device provides accurate measurement of transcutaneous carbon dioxide diffusing though the skin detects a luminescent response of a carbon dioxide-sensitive film, providing an accurate reflection of a person's blood carbon dioxide levels. The device employs a charge-to-digital converter (CDC) architecture operable for implementation of a time-domain dual lifetime referencing computation to measure transcutaneous carbon dioxide. This potential product enables highly accurate and precise measurements of transcutaneous carbon dioxide while minimizing interference from confounding factors.