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231.发明申请公开(公告)号：US20180325111A1
公开(公告)日：2018-11-15
申请号：US15773993
申请日：2016-10-31
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Yi Yan YANG , QingXing XU , Majad KHAN , Chuan YANG , Shrinivas VENKATARAMAN
CPC classification number: A01N43/32 , A01N33/12 , A01N37/44 , A61K47/59 , C02F1/50 , C08G73/02 , C08L79/08
Abstract: This invention relates to an antibacterial polymer-modified particle comprising a particle core, wherein a polymer is covalently bound to the particle core via a linker and said polymer comprises a branched, amphiphilic cationic polyalkylene imine backbone having amine or amino functional groups and wherein optionally all or some of the amine or amino groups of the polymer have been further reacted with amphiphilic cyclic carbonates carrying a quaternary ammonium group under formation of a urethane bond. In a preferred embodiment the core is a silica core functionalized with the polyelkyleneimine. The invention also relates to methods of making such particles and their use in water disinfection applications.
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公开(公告)号：US20180320000A1
公开(公告)日：2018-11-08
申请号：US15769709
申请日：2016-10-19
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Yugen ZHANG , Yuan YUAN
IPC: C09D5/14 , A61K31/4164 , A61K47/02 , C07F3/06
Abstract: A coating comprising a metal-organic framework, wherein the metal-organic framework having a zeolitic structure comprising at least one multivalent metal species and at least one organic ligand (such as zeolitic imidazolate framework (ZIF)). Said coating has a topography comprising an array of projections, and each projection having at least one tapered distal end. There is also provided a method of coating substrates with the disclosed coating and use of said coating as a disinfectant, an antiseptic, or an antibiotic. Such use is possible because the tapered distal end of the disclosed zeolitic structure exerting higher pressure on any microbial cell that comes into contact with the disclosed coating, thereby piercing through the cell membrane more easily, causing cell deformation and lysis.
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公开(公告)号：US10117946B2
公开(公告)日：2018-11-06
申请号：US14655223
申请日：2013-12-24
Applicant: Agency for Science, Technology and Research
Inventor： Michael R. Reithofer , Charlotte A. E. Hauser , Kiat Hwa Chan , Archana Mishra
IPC: A01N55/02 , A61K31/28 , A61K47/48 , A61K31/282 , A61K38/08 , A61K31/555
Abstract: The present invention relates to hydrogels comprising a first peptide with a covalently linked bioactive agent and optionally a second peptide. The present invention further relates to uses of the hydrogel for delivery of the bioactive agent or as an implant. The present invention further relates to drug delivery devices, implant, pharmaceutical or cosmetic compositions comprising the hydrogel. The present invention further relates to methods of local treatment of diseases and to methods for preparing the first peptide and the hydrogels.
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公开(公告)号：US20180311877A1
公开(公告)日：2018-11-01
申请号：US15772042
申请日：2016-10-27
Inventor： Mohamed Sultan Mohiddin SAIFULLAH , Siew Ling Karen CHONG , Yee Chong LOKE , Alvin CHENG , Nicholas LEONG
CPC classification number: B29C45/37 , B81C99/009 , B81C2201/0153 , B82Y40/00 , C23C14/14 , C23C14/34 , C25D1/10 , G03F7/0002
Abstract: An injection mold insert with hierarchical structures and a method for method of making such injection mold inserts are provided. The method includes imprinting a primary imprint structure on an article and imprinting a secondary imprint structure on the primary imprint structure on the article. The secondary imprint structure includes a plurality of shapes, each of the plurality of shapes being substantially smaller than shapes of the primary imprint structure. The method further includes bonding the article to a substrate, sputter-coating the article with a metal film as an electroforming seed layer, and electroforming the injection mold insert over the article. Finally, the method includes dissolving the article to define the injection mold insert having a negative replica of the primary and secondary imprint structures.
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公开(公告)号：US10111787B2
公开(公告)日：2018-10-30
申请号：US14424379
申请日：2013-08-26
Applicant: Agency for Science, Technology and Research
Inventor： Jackie Y. Ying , Guolin Xu , Rensheng Deng , Xiaojun Chen
Abstract: Various embodiments provide an apparatus for a diaper. The apparatus has two electrodes and an electronic device. The electronic device is coupled to the two electrodes. The two electrodes are operable to generate a potential difference when they are electrically connected together by ionized liquid. The electronic device is operable to generate an alarm signal when the potential difference is generated. Various other embodiments relate to a corresponding system, diaper and method of manufacturing an electrode.
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Patent Agency Ranking
公开(公告)号：US10107748B2
公开(公告)日：2018-10-23
申请号：US15033981
申请日：2014-11-04
Applicant: Agency for Science, Technology and Research
Inventor： Chi Lok Wong , Malini Olivo
IPC: G01N21/55 , G01N21/552 , G01N21/21
Abstract: An optical sensing device is provided, including a first polarizer, a second polarizer, wherein the first polarizer and the second polarizer have respective transmission axes aligned in orthogonal directions, an SPR sensor arrangement including an SPR sensing surface, the SPR sensor arrangement arranged to receive an incident light beam passed through a polarizer to be reflected at the SPR sensing surface and transmitted through a second polarizer to provide a transmitted light beam, a detector arrangement configured to detect the transmitted light beam, the transmitted light beam including a sensing signal and a reference signal, and a processor electrically coupled to the detector arrangement, the processor configured to perform a subtraction operation between the sensing signal and the reference signal. The optical sensing is based on a differential measurement scheme. The subtraction between the sensing signal and the reference signal cancels the common path noise and enhances the sensor resolution.
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公开(公告)号：US10098580B2
公开(公告)日：2018-10-16
申请号：US15037791
申请日：2014-11-19
Inventor： Ee Sin Ng , How Lung Eng , Wei Shih Derrick Chan , That Mon Htwe , Wiriyanto Darsono
Abstract: There is provided a hypermotor activity detection system, including: a video capture device configured to monitor a patient and obtain a video input; and a processing system configured to process the video input. The processing system includes: an optical flow module configured to carry out an optical flow analysis on a video input region determined from the video input, and further determine a flow field magnitude of the video input region; and a local motion reference module configured to obtain a local motion reference value. The local reference module includes: a division module; a sub-window flow module; a local motion magnitude module; and a local motion comparison module. Further, a corresponding method for detecting hypermotor activity is provided.
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公开(公告)号：US20180290882A1
公开(公告)日：2018-10-11
申请号：US15574349
申请日：2016-06-10
Applicant: Agency for Science, Technology and Research
Inventor： Daniel Minwoo Rhee , Peter Hyun Kee Chang
Abstract: According to various embodiments, there is provided a method for fabricating a semiconductor package, the method including forming a cap structure and a pillar from a first wafer; bonding the first wafer to a second wafer; and filling a gap between the pillar and the cap structure with a mold compound.
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公开(公告)号：US10094957B2
公开(公告)日：2018-10-09
申请号：US15470030
申请日：2017-03-27
Inventor： Wei Du , Tao Wang , Christian Albert Nijhuis , Hong-Son Chu , Lin Wu
Abstract: A method of producing electronic plasmons by applying a bias to a molecular tunnel junction to excite plasmons, in which the molecular tunnel junction contains a top metallic electrode formed of a eutectic metal alloy and a metal oxide, a bottom metallic electrode formed of a transition metal, and a self-assembled monolayer formed of a plurality of organic molecules disposed between the top metallic electrode and the bottom metallic electrode. Also disclosed are a molecular tunnel junction for producing electronic plasmons and a method for preparing such a molecular tunnel junction.
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公开(公告)号：US20180273657A1
公开(公告)日：2018-09-27
申请号：US15916133
申请日：2018-03-08
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Fuke Wang , Fei Wang , Chaobin He , Yi Ting Chong
Abstract: There is provided a resin formulation comprising a base acrylate monomer or oligomer, a solubilizing acrylate monomer or oligomer, a photoinitiator compound, a photoabsorber compound, and a photochromic dye, wherein the solubilizing acrylate monomer or oligomer comprises a functional group selected from the group consisting of hydroxyl, alkoxyl, carboxylic acid, amine, alkylamine, amide, alkylamide, alkylacrylate, acrylate, alkyl and heterocycloalkyl. There is also provided a method of preparing the resin formulation and uses of the resin formulation thereof.
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