公开(公告)号：US20150131244A1

公开(公告)日：2015-05-14

申请号：US14395467

申请日：2013-04-03

Applicant: CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITE DE FRANCHE-COMTE

Inventor： Sylvain Ballandras ,  Bruno Francois

IPC: G01K11/26 ,  H05K1/18

CPC classification number: G01K11/265 ,  B23K1/0016 ,  B23K2101/38 ,  H01L2224/45014 ,  H01L2224/45147 ,  H01L2224/45169 ,  H01L2224/48091 ,  H01L2224/8592 ,  H01L2924/181 ,  H05K1/0293 ,  H05K1/0306 ,  H05K1/053 ,  H05K1/181 ,  H05K3/103 ,  H05K3/285 ,  H05K3/3426 ,  H05K2201/1006 ,  H05K2201/10068 ,  H05K2201/10075 ,  H05K2201/10083 ,  H05K2201/10098 ,  H05K2201/10151 ,  H05K2201/1028 ,  H05K2201/10287 ,  H05K2201/10977 ,  H05K2203/049 ,  Y02P70/611 ,  H01L2924/00014 ,  H01L2924/00012

Abstract: The electrical device (2, 202) according to the invention comprises a first electrical component (4) and a second electrical component (6) connected to each other via an electrical connection means (26) having an electrically insulating support plate (24), and a weld joint (22) deposited on the support plate (24).The weld joint (22) has a melting temperature (TO significantly lower than an ambient operating temperature (Ta) to which at least one of the two electrical components and the electrical connection means (26) are provided to be subjected.The electrical device (2) comprises a cement (28) that completely covers the exposed weld joint (22), the material of the cement (28) being chosen to maintain its adhesion and its tightness with respect to the weld joint (22) when the ambient operating temperature (Ta) is applied.

Abstract translation: 根据本发明的电气设备（2,202）包括通过具有电绝缘支撑板（24）的电连接装置（26）彼此连接的第一电气部件（4）和第二电气部件（6） 和沉积在支撑板（24）上的焊接接头（22）。 焊接接头（22）的熔融温度（TO显着低于设置有两个电气部件和电连接装置26中的至少一个）的环境工作温度（Ta），电气装置 2）包括完全覆盖暴露的焊接接头（22）的水泥（28），选择水泥（28）的材料以在环境工作温度下保持其粘合力及其相对于焊接接头（22）的密封性 （Ta）。

公开(公告)号：US20150004190A1

公开(公告)日：2015-01-01

申请号：US14374121

申请日：2013-01-25

Applicant: Institut National De La Sante Et De La Recherche Medicale (INSERM) ,  Universite Paris Descartes ,  Centre National de la Recherche Scientifique (C.N.R.S.) ,  Universite Paris Diderot - Paris 7

Inventor： Morgane Bomsel ,  Daniela Tudor

IPC: A61K39/21 ,  C12N7/00

CPC classification number: A61K39/21 ,  A61K39/12 ,  A61K2039/507 ,  A61K2039/53 ,  A61K2039/541 ,  A61K2039/55522 ,  C07K16/1063 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/34 ,  C07K2317/52 ,  C07K2317/76 ,  C07K2317/92 ,  C12N7/00 ,  C12N2740/16034 ,  C12N2740/16122 ,  C12N2740/16134 ,  C12N2795/14143

Abstract: Novel antibodies and peptides relating to HIV are disclosed, as are vaccine compositions containing such antibodies and peptides. The compounds and compositions of the invention are of use in prevention and treatment of HIV, and in particular for inducing mucosal immunity to HIV.

Abstract translation: 公开了与HIV相关的新型抗体和肽，以及含有这种抗体和肽的疫苗组合物。 本发明的化合物和组合物可用于预防和治疗HIV，特别是用于诱导对HIV的粘膜免疫。

公开(公告)号：US20140370611A1

公开(公告)日：2014-12-18

申请号：US14362707

申请日：2012-12-06

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) ,  ECOLE NORMALE SUPERIEURE

Inventor： Charlie Gosse ,  Annie Lemarchand ,  Ludovic Jullien ,  Thomas Le Saux ,  Kais Zrelli

IPC: G06F19/00

CPC classification number: G16C20/10 ,  B01J19/0033 ,  B01J19/0093 ,  B01J2219/00286 ,  B01J2219/00585 ,  B01J2219/00698 ,  B01J2219/00702 ,  B01J2219/00869 ,  B01J2219/00882 ,  B01J2219/00885 ,  B01J2219/00957 ,  B01J2219/00961 ,  B01J2219/0097 ,  B01J2219/00986 ,  B01J2219/00995 ,  G16C10/00 ,  Y10T436/143333

Abstract: The method according to the invention includes choosing a reaction presumed reaction mechanism; selecting, for said mechanism, at least one first function characteristic of a thermokinetic property that is invariant with the periodic variation frequency of a control parameter influencing said reaction, the first characteristic function being calculated at least from first-order oscillation amplitudes of the concentration of at least one of the species involved in said reaction. The method includes calculating a plurality of values of the first characteristic function from first-order oscillation amplitudes obtained experimentally and analyzing the calculated values of the first characteristic function to determine whether the first characteristic function is constant based on the calculated values, and if the first characteristic function is constant, assigning the presumed mechanism to said reaction.

Abstract translation: 根据本发明的方法包括选择反应推定的反应机理; 对于所述机理，选择与影响所述反应的控制参数的周期性变化频率不变的热动力学性质的至少一个第一函数特征，所述第一特征函数至少从第一特征函数的一阶振荡幅度 涉及所述反应的物质中的至少一种。 该方法包括从实验获得的一阶振荡幅度计算第一特征函数的多个值，并分析第一特征函数的计算值，以基于计算值确定第一特征函数是否恒定，以及如果第一特征函数 特征函数是恒定的，将推测机制分配给所述反应。

公开(公告)号：US20140302421A1

公开(公告)日：2014-10-09

申请号：US14350783

申请日：2012-10-10

Applicant: AREVA ,  ARMINES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Béatrice Sala ,  Frédéric Grasset ,  Elodie Tetard ,  Kamal Rahmouni ,  Abdelkader Sirat ,  Dominique Goeuriot ,  Baroudi Bendjeriou ,  Hisasi Takenouti

IPC: H01M4/90 ,  H01M4/88 ,  C25B11/04

CPC classification number: H01M4/8875 ,  C25B11/04 ,  H01M4/9016 ,  H01M4/9033 ,  H01M8/1213 ,  H01M2008/1293 ,  Y02P70/56

Abstract: The invention relates to an electrode for an electrochemical cell which exhibits good electron conductivity and good chemical conductivity, as well as good cohesion with the solid electrolyte of the electrochemical cell. To do this, this electrode is made from a ceramic, which is a perovskite doped with a lanthanide having one or more degrees of oxidation and with a complementary doping element taken from the following group: niobium, tantalum, vanadium, phosphorus, arsenic, antimony, bismuth.

Abstract translation: 本发明涉及电化学电池的电极，其具有良好的电子传导性和良好的化学导电性，以及与电化学电池的固体电解质的良好的内聚力。 为此，该电极由陶瓷制成，陶瓷是掺杂有镧系元素的钙钛矿，其具有一个或多个氧化度，并且具有取自以下组的互补掺杂元素：铌，钽，钒，磷，砷，锑 ，铋。

公开(公告)号：US20130165667A1

公开(公告)日：2013-06-27

申请号：US13777799

申请日：2013-02-26

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) ,  ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER ,  UNIVERSITE SIDI MOHAMMED BEN ABDELLAH

Inventor： Marc TAILLEFER ,  Hamid KADDOURI ,  Fouad OUAZZANI ,  Armelle OUALI

IPC: C07B37/02 ,  C07C41/06 ,  C07C253/30 ,  C07D231/12

CPC classification number: C07F9/5045 ,  C07F9/5022

Abstract: A method for the creation of a carbon-carbon (C—C) bond or of a carbon-heteroatom (C-HE) bond includes reacting a compound carrying a leaving group with a nucleophilic compound carrying a carbon atom or a heteroatom (HE) capable of replacing the leaving group, thus creating a C—C or C-HE bond, in which process the reaction is carried out in the presence of an effective amount of a catalytic system comprising at least one copper/butadienylphosphine complex.

Abstract translation: 产生碳 - 碳（CC）键或碳 - 杂原子（C-HE）键的方法包括使带有离去基团的化合物与携带碳原子的亲核化合物或能够 代替离去基团，从而产生CC或C-HE键，其中反应在有效量的包含至少一种铜/丁二烯基膦络合物的催化体系的存在下进行。

公开(公告)号：US20040235868A1

公开(公告)日：2004-11-25

申请号：US10793941

申请日：2004-03-08

Applicant: Centre National De La Recherche Scientifique (C.N.R.S.) ,  Institute of Experimental Botany ,  Academy of Science of the Czech Republic

Inventor： Laurent Meijer ,  Emile Bisagni ,  Michel Legraverend ,  Miroslav Strnad

IPC: A61K031/52 ,  C07D473/14

CPC classification number: C07D473/16

Abstract: This invention provides 2-, 6, and 9-substituted purine derivatives, particularly 2(1-R hydroxymethylpropylamino)-6-benzylamino-9-isopropyl purine, having, in particular, antiproliferative properties, and suitable for use as pharmaceutical compositions and herbicidal compositions. Also provided are pharmaceutical compositions and herbicidal compositions comprising the 2-, 6, and 9-substituted purine derivatives, and methods of treatment using the 2-, 6, and 9-substituted purine derivatives.

Abstract translation: 本发明提供了具有特别是抗增殖性质的2-，6-和9-取代的嘌呤衍生物，特别是2（1-R羟甲基丙基氨基）-6-苄氨基-9-异丙基嘌呤，并且适合用作药物组合物和除草剂 组合物。 还提供了包含2-，6和9-取代的嘌呤衍生物的药物组合物和除草组合物，以及使用2-，6和9-取代的嘌呤衍生物的治疗方法。

公开(公告)号：US20020049218A1

公开(公告)日：2002-04-25

申请号：US09986329

申请日：2001-11-08

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIGUE (C.N.R.S.)

Inventor： Laurent Meijer ,  Emile Bisagni ,  Michel Legraverend

IPC: A61K031/52 ,  C07D473/34

CPC classification number: C07D473/16

Abstract: This invention provides 2-, 6, and 9-substituted purine derivatives, particularly 2(1-R hydroxymethylpropylamino)-6-benzylamino-9-isopropyl purine, having, in particular, antiproliferative properties, and suitable for use as pharmaceutical compositions and herbicidal compositions. Also provided are pharmaceutical compositions and herbicidal compositions comprising the 2-, 6, and 9-substituted purine derivatives, and methods of treatment using the 2-, 6, and 9-substituted purine derivatives.

Abstract translation: 本发明提供了具有特别是抗增殖性质的2-，6-和9-取代的嘌呤衍生物，特别是2（1-R羟甲基丙基氨基）-6-苄氨基-9-异丙基嘌呤，并且适合用作药物组合物和除草剂 组合物。 还提供了包含2-，6和9-取代的嘌呤衍生物的药物组合物和除草组合物，以及使用2-，6和9-取代的嘌呤衍生物的治疗方法。