公开(公告)号：US12172131B2

公开(公告)日：2024-12-24

申请号：US18437727

申请日：2024-02-09

Applicant: EMD Millipore Corporation

Inventor： Christopher A. Scott ,  Kurt Greenizen ,  Paul Sydlowski

IPC: B01D63/08 ,  B01D61/18 ,  B01D61/20

Abstract: A funnel-less filtration device that attaches directly to a storage container such as a cell culture media bottle. The device includes a filter collar containing one or more membranes, an inlet with a coupling device for attaching the filter device to a supply of liquid to be filtered, an outlet at a lower portion of the collar, a vacuum port in the collar below the membrane(s) and a filtered vent in the collar above the membrane(s).

公开(公告)号：US12172108B2

公开(公告)日：2024-12-24

申请号：US17262356

申请日：2019-08-12

Applicant: EMD Millipore Corporation

Inventor： Michael James Susienka ,  Jeremy Perreault ,  Joseph Geringer ,  Brian Hillier ,  Joseph Muldoon ,  John Paul Amara

IPC: B01D63/08 ,  B01D27/14 ,  B01D35/30

Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

公开(公告)号：US20240309195A1

公开(公告)日：2024-09-19

申请号：US18578419

申请日：2022-08-22

Applicant: EMD Millipore Corporation

Inventor： Kevin Wu ,  Kelly Wolfe ,  Anja Dedeo ,  Ryan Amara ,  Gerard Libby ,  Paul Sydlowski ,  Katelyn Kavanaugh ,  Trisha Bailey ,  Nathan T. Allen

IPC: C08L33/26 ,  C08J9/28 ,  G01N27/447

CPC classification number: C08L33/26 ,  C08J9/28 ,  G01N27/44747 ,  C08J2333/26

Abstract: An acrylamide gel formulation for use in electrophoresis, and a system and method for electrophoretic gel casting. In some embodiments, the system comprises a UV-Vis curing light source, and an acrylamide formulation that allows a resolving gel and a stacking gel to be photopolymerized in a single step. In some embodiments, the resolving solution formulation comprises acrylamide and bis-acrylamide, Bis-Tris buffering agent, and lithium phenyl-2, 4, 6-trimethylbenzoyl-phosphinate (LAP) as a water-soluble photoinitiator, which allows the solution to be photopolymerized using UV radiation within a certain wavelength. In some embodiments, a dilution buffer formulation comprises acrylamide and bis-acrylamide, Bis-Tris buffering agent, and lithium phenyl-2, 4, 6-trimethyl-benzoyl-phosphinate (LAP). The dilution buffer may be added to the resolving solution in a selected amount in order to modify the concentration of the acrylamide to a desired concentration.

公开(公告)号：US12090436B2

公开(公告)日：2024-09-17

申请号：US18165543

申请日：2023-02-07

Applicant: EMD Millipore Corporation

Inventor： Joseph Geringer ,  Robert Castro ,  Martin Szyk ,  Sophie Daudenarde ,  Joseph Almasian

IPC: B01D46/42 ,  B01D46/00

CPC classification number: B01D46/4272 ,  B01D46/0004

Abstract: Port protection device particularly suited for an encapsulated filter unit. In certain embodiments, the protection device comprises a main body defining an internal region configured to receive a port or the like protruding from an encapsulated filter. In certain embodiments, the main body includes a slot that allows for easy removal of the protection device from the port or the like. A tube management system may be provided to receive and hold tubing. One suitable tube management system includes two spaced tangs that extend from the main body of the protection device and are configured to cooperatively receive and hold tubing between them.

公开(公告)号：US12059644B2

公开(公告)日：2024-08-13

申请号：US15301781

申请日：2015-06-23

Applicant: EMD Millipore Corporation

Inventor： Sal Giglia ,  David Nhiem ,  Sherry Ashby Leon ,  Gabriel Tkacik

IPC: B01D39/16

CPC classification number: B01D39/1623 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/065

Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.

公开(公告)号：US11975293B2

公开(公告)日：2024-05-07

申请号：US17655093

申请日：2022-03-16

Applicant: EMD Millipore Corporation

Inventor： Alison Dupont

IPC: B01D63/10 ,  B01D61/18 ,  C12M1/00 ,  B01D65/02 ,  B01D65/08

CPC classification number: B01D63/103 ,  C12M29/10 ,  B01D61/18 ,  B01D65/02 ,  B01D65/08 ,  B01D2311/04 ,  B01D2311/06 ,  B01D2313/143 ,  B01D2315/10 ,  C12M29/04

Abstract: Filter elements for perfusion systems and methods are provided. A filter element sheet includes a microporous membrane having a mean pore size of at least about 0.65 μm and a feed spacer comprising woven fibers and having an open area of at least about 35%. The filter element sheet can be arranged within a filter element, for example, in a spiral-wound format or in a cassette format. A perfusion system includes at least one filter element and a pump configured to control flow of a liquid feed through the at least one filter element.

公开(公告)号：US20230321574A1

公开(公告)日：2023-10-12

申请号：US18334925

申请日：2023-06-14

Applicant: EMD Millipore Corporation

Inventor： Akshat Gupta ,  Dana Kinzlmaier ,  Kara Pizzelli ,  Elizabeth Goodrich

IPC: B01D39/18 ,  B01D37/02 ,  D21C9/00 ,  C12M1/12 ,  B01D71/10

CPC classification number: B01D39/18 ,  B01D37/025 ,  D21C9/004 ,  D21C9/005 ,  C12M37/02 ,  B01D71/10

Abstract: Treatment methods for reduction of (1→3)-β-D-glucan leachables from cellulose-containing filter materials are described.

公开(公告)号：US20230302409A1

公开(公告)日：2023-09-28

申请号：US18034243

申请日：2021-11-16

Applicant: EMD Millipore Corporation

Inventor： Heejin Lee ,  Michael James Susienka ,  Johnathan Lawson ,  John Paul Amara ,  Joseph Michael Almasian ,  Sean Foley ,  James Ormond

IPC: B01D61/18 ,  B01D63/08

CPC classification number: B01D61/18 ,  B01D63/082 ,  B01D2313/54 ,  B01D2313/13 ,  B01D2313/105 ,  B01D2313/125 ,  B01D2313/16 ,  B01D2313/06 ,  B01D2313/041

Abstract: An apparatus for treating a biological fluid, comprising a plurality of filtration devices. In some embodiments, each of the plurality of filtration devices comprising at least one inlet and at least one outlet; and a first insert plate and a second insert plate opposite the first insert plate, wherein the plurality of filtration devices is disposed therebetween. In some embodiments, each filtration device has a vent port. A manifold for each of the inlets, outlets, and vent ports is optionally fluidly connected. In another embodiment, hose barb connectors or the like may be protected from damage and/or exposure by being recessed in the device or positioned at a periphery of the device. Embodiments include apparatus and methods to achieve dripless connect/disconnect and to reduce the number of sterile-to-sterile connections.

公开(公告)号：US11712647B2

公开(公告)日：2023-08-01

申请号：US17235071

申请日：2021-04-20

Applicant: EMD Millipore Corporation

Inventor： Akshat Gupta ,  Dana Kinzlmaier ,  Kara Pizzelli ,  Elizabeth Goodrich

IPC: B01D39/18 ,  B01D37/02 ,  D21C9/00 ,  B01D71/10 ,  C12M1/12

CPC classification number: B01D39/18 ,  B01D37/025 ,  B01D71/10 ,  C12M37/02 ,  D21C9/004 ,  D21C9/005

Abstract: Treatment methods for reduction of (1→3)-β-D-glucan leachables from cellulose-containing filter materials are described.

公开(公告)号：US11623816B2

公开(公告)日：2023-04-11

申请号：US17377606

申请日：2021-07-16

Applicant: EMD Millipore Corporation

Inventor： John Gugliotti ,  Michael Gugliotti

IPC: B65D85/24 ,  B65D33/16 ,  A61M5/32

Abstract: A needle protector, having a flexible material, a pocket defining an internal volume, a wrapping strap having a plurality of holes, and a main body disposed between the pocket and the wrapping strap; at least one rigid body or cylinder for placement within the internal volume; and; a pin for placement within one of the plurality of holes, wherein the pin is capable of releasably locking the pocket and the main body when the wrapping strap is wrapped around the pocket and the main body.