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公开(公告)号：US20190289828A1
公开(公告)日：2019-09-26
申请号：US16441313
申请日：2019-06-14
摘要： A system and method are disclosed for tracking animals, which may include production animals as well as pets. The system and method may comprise a tag system that is attached to an animal that generally has at least a near-field-communication (NFC) tag. The tag system comprises at least an NFC tag and a radio-frequency identification (RFID) tag. For NFC tags, such tags may be read with a portable computing device, such as a mobile telephone running NFC reader application software. The phone may communicate with a communications network and ultimately a computer server in order to relay information received from a respective electronic tag. The electronic tags may be fastened, embedded, or ingested by an animal. The electronic tags may be part of a mechanical coupling. Each mechanical coupling may comprise a different structure depending on the whether the tags are fastened to, embedded in, or ingested by the animal.
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22.发明授权公开(公告)号：US10383854B2
公开(公告)日：2019-08-20
申请号：US15286133
申请日：2016-10-05
IPC分类号： A61K31/42 , A61K31/231 , A61K31/44 , A61K31/4402 , A61K31/4745 , A61K31/7048 , A61K45/06 , A61K47/08 , A61K47/22 , A61K9/00 , A01N43/40 , A61K47/26 , A61K47/14 , A61K47/10 , A61K38/15 , A61K31/415 , A61K31/366 , A01N43/80 , A01N49/00 , A61K9/06 , A61K31/215 , A61K31/22
摘要： This invention relates to topical compositions for combating ectoparasites and endoparasites in animals, comprising at least one isoxazoline active agent and a pharmaceutically acceptable carrier, optionally in combination with one or more additional active agents. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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23.发明申请公开(公告)号：US20190249196A1
公开(公告)日：2019-08-15
申请号：US16393743
申请日：2019-04-24
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00 , A61K39/12
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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公开(公告)号：US10363300B2
公开(公告)日：2019-07-30
申请号：US15888718
申请日：2018-02-05
IPC分类号： A61K39/12 , A61K39/00 , A61K39/135 , C07K14/005 , C12N7/00 , A61K39/385 , C07K14/32
摘要： The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. The invention further encompasses methods of making or producing antigenic polypeptides or antigens.
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公开(公告)号：US20190216920A1
公开(公告)日：2019-07-18
申请号：US16262774
申请日：2019-01-30
IPC分类号： A61K39/255 , A61K39/12
CPC分类号： A61K39/255 , A61K39/12 , A61K2039/5254 , A61K2039/552 , C12N2710/16334 , C12N2740/13022 , C12N2830/60
摘要： The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
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公开(公告)号：US11964977B2
公开(公告)日：2024-04-23
申请号：US17324288
申请日：2021-05-19
发明人： Hannes Fiepko Koolman , Bart Herlé , Alan Long
IPC分类号： A61K31/5025 , A61P33/10 , C07D487/04
CPC分类号： C07D487/04 , A61P33/10
摘要： This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.-
公开(公告)号：US20240076321A1
公开(公告)日：2024-03-07
申请号：US18516237
申请日：2023-11-21
发明人： Luis Alejandro HERNANDEZ , Christine Margaret MUEHLENTHALER , Eric Martin VAUGHN , Gregory HAIWICK
IPC分类号： C07K14/005 , A61K39/12 , C12N7/00 , C12P21/02
CPC分类号： C07K14/005 , A61K39/12 , C12N7/00 , C12P21/02 , A61K39/00 , C12N2750/10022 , C12N2750/10023 , C12N2750/10034
摘要： Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of the same PCV2b and/or different subtype; the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of the same PCV2b or a different subtype; and/or the prevention or treatment of a disease caused by an infection with PCV2 of the same PCV2b and/or a different subtype. The present invention in particular relates to PCV2 subtype b (PCV2b) ORF2 proteins characterized in that they contain at least one mutation in the BC loop that such that the expressed protein is preferably expressed in a higher amount compared to a PCV2 ORF2 protein that does not contain such mutation.
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28.发明公开公开(公告)号：US20230175017A1
公开(公告)日：2023-06-08
申请号：US17812732
申请日：2022-07-15
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00
CPC分类号： C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00 , C12N2760/16163 , C12N2710/16363 , C12N2760/18163 , C12N2710/16334 , C12N2710/16343 , C12N2720/10034 , C12N2760/18134 , C12N2830/20 , C12N2830/50 , C12N2840/203 , C12N2710/16311
摘要： The invention relates to a bonding and forming device for an inner box of a paper box and surface paper. The bonding and forming device comprises a stand, a lifting platform, a paper box inner support member, a flanging pressing plate, an ejector pin, a left hairbrush, a right hairbrush, a first pushing part, a front hairbrush, a rear hairbrush and a second pushing part and also comprises a driving device, a first control device a second control device, a third control device, a fourth control device and a fifth control device, wherein the driving device is used for driving the ejector pin to rise or fall; the first control device is used for controlling the paper box inner support member to rise or fall; the second control device is used for controlling the left hairbrush and the right hairbrush to stretch; the third control device is used for controlling the first pushing part to stretch; the fourth control device is used for controlling the front hairbrush and the rear hairbrush to stretch; the fifth control device is used for controlling the second pushing part to stretch; an inhibiting device is arranged between the first control device and the driving device; and the paper box inner support member and the flanging pressing plate are respectively provided with a through hole for the ejector pin to pass through. By adopting the technical scheme, according to the bonding and forming device for the inner box of the paper box and the surface paper, provided by the invention, the inner box and other surfaces of the surface paper can be automatically bonded to be formed after a bottom plate of the inner box and the bottom surface of the surface paper are bonded. The degree of automation is high and the production efficiency is high.
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29.发明授权公开(公告)号：US11484528B2
公开(公告)日：2022-11-01
申请号：US16588439
申请日：2019-09-30
摘要： This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
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公开(公告)号：US20220201983A1
公开(公告)日：2022-06-30
申请号：US17457792
申请日：2021-12-06
发明人： James ALLAN , Samuel David BELL , Christian Helmut EPE , Loic Patrick LE HIR DE FALLOIS , Willy W. LEE , Jason J. LOCKLIN
IPC分类号： A01K27/00 , A61P33/00 , A61K31/422 , A01N43/80 , A61K9/00
摘要： Provided herein are long-acting antiparasitic devices comprising parasiticidal isoxazoline active agent for external use on an animal to treat and/or prevent parasitic infestations by ectoparasites, and in some embodiments, also parasitic infections. The disclosure also describes methods and uses of the antiparasitic external devices to treat and/or prevent parasitic infestations and/or infections in an animal.
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