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公开(公告)号：US12083290B2
公开(公告)日：2024-09-10
申请号：US16841341
申请日：2020-04-06
发明人： S. Ray Isaacson
CPC分类号： A61M25/02 , A61M2025/024 , A61M2205/18 , A61M2205/3331 , A61M2205/3375 , G16H10/60
摘要： A method to manage flushing of a catheter assembly a clamp configured to clamp an extension tube of a catheter assembly. The clamp may include an acoustic sensor configured to detect fluid flowing through the extension tube. The clamp and the acoustic sensor may be disposed outside of the extension tube. The clamp may include a pinch clamp or a non-pinch clamp. The acoustic sensor may be embedded in the clamp. The method may include detecting, via the acoustic sensor, fluid flowing through the extension tube.
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公开(公告)号：US20240293055A1
公开(公告)日：2024-09-05
申请号：US18572964
申请日：2022-06-23
CPC分类号： A61B5/150022 , A61B5/150068 , A61B5/150259 , A61B5/150343 , A61B5/150748 , A61B5/151
摘要： A device for obtaining a blood sample may include a holder for receiving a sample source, the holder having an actuation portion and a port; a container engagement portion connected to the holder; and a collection container removably connectable to the container engagement portion, the container defining a collection cavity, wherein the actuation portion comprises at least two wings that are angled relative to a patient's finger held in the holder to create a pressure gradient towards a fingertip of the patient's finger.
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公开(公告)号：US12076146B2
公开(公告)日：2024-09-03
申请号：US17059598
申请日：2019-06-06
发明人： Peng Li , Scott Wentzell
IPC分类号： A61B5/15
CPC分类号： A61B5/150755 , A61B5/15003 , A61B5/150213 , A61B5/150251 , A61B5/150351
摘要： A blood separation device that decouples and separates the blood collection process from the plasma separation process is disclosed. The blood separation device includes a sample collection module, an activation module, and a separation module. Because the plasma separation happens after the blood separation device is disconnected from a patient, the device performance is no longer affected by patient blood pressure and needle gauge, and patient discomfort is greatly reduced.
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公开(公告)号：US20240280578A1
公开(公告)日：2024-08-22
申请号：US18627209
申请日：2024-04-04
CPC分类号： G01N33/582 , C08G61/02 , C08G2261/124 , C08G2261/1424 , C08G2261/148 , C08G2261/1644 , C08G2261/312 , C08G2261/3142
摘要： Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.
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公开(公告)号：US20240280395A1
公开(公告)日：2024-08-22
申请号：US18642437
申请日：2024-04-22
发明人： Gary SEARLE , Francis L. ROSS, III
IPC分类号： G01F11/02 , A61M5/142 , A61M5/168 , A61M5/172 , A61M5/178 , A61M5/31 , A61M5/315 , B65B3/00 , G01R33/07 , G16H20/17
CPC分类号： G01F11/027 , A61M5/14248 , A61M5/16804 , A61M5/16831 , A61M5/172 , A61M5/31511 , G01R33/072 , A61M5/1782 , A61M2005/3125 , A61M2205/3317 , A61M2205/3389 , A61M2205/3576 , A61M2205/50 , B65B3/003 , G16H20/17
摘要： A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to be attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing.
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公开(公告)号：US20240279734A1
公开(公告)日：2024-08-22
申请号：US18643870
申请日：2024-04-23
发明人： Stephen P.A. Fodor , Glenn K. Fu
IPC分类号： C12Q1/6874 , C12N15/10 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686 , C12Q1/6869 , C12Q1/6876 , G16B25/00 , G16B25/10 , G16B25/20 , G16B30/00
CPC分类号： C12Q1/6874 , C12N15/1065 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686 , C12Q1/6869 , C12Q1/6876 , G16B25/00 , G16B25/20 , G16B30/00 , G16B25/10
摘要： Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical molecules by attachment of a diverse set of labels. Each copy of a molecule randomly chooses from a non-depleting reservoir of diverse labels. Detection may be by a variety of methods including hybridization based or sequencing. Molecules that would otherwise be identical in information content can be labeled to create a separately detectable product that is unique or approximately unique in a collection. This stochastic transformation relaxes the problem of counting molecules from one of locating and identifying identical molecules to a series of binary digital questions detecting whether preprogrammed labels are present. The methods may be used, for example, to estimate the number of separate molecules of a given type or types within a sample.
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公开(公告)号：US20240277973A1
公开(公告)日：2024-08-22
申请号：US18642514
申请日：2024-04-22
发明人： Michael Garrison , Bart D. Peterson , Ralph L. Sonderegger , Jonathan Karl Burkholz , Nathan Mitchell
CPC分类号： A61M25/0606 , A61M5/158 , A61M5/1626 , A61M25/0097 , A61M25/0113 , A61M25/0631 , A61M25/0637 , A61M2005/1585 , A61M2025/0266 , A61M25/0693
摘要： An IV catheter system may have a catheter component and a needle component. The catheter component may have a catheter hub, a cannula extending distally from the catheter hub, and a push feature extending outward from the catheter hub. The push feature may have an outer surface that receives contact from a digit to move the IV catheter system from an insertion configuration, in which the needle is within the cannula, to a fluid delivery configuration, in which the needle is outside the catheter hub. The needle component may have a needle hub and a needle extending distally from the needle hub along an axis. The push feature may be formed of a flexible material that causes the push feature, in response to pressure exerted on the outer surface by a dressing securing the catheter component to a patient, to deflect the outer surface toward the cannula axis.
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公开(公告)号：US20240277945A1
公开(公告)日：2024-08-22
申请号：US18487655
申请日：2023-10-16
发明人： Richard CRONENBERG
CPC分类号： A61M5/3213 , A61M5/3202 , A61M5/3276 , A61M5/24 , A61M2005/2407 , A61M5/31525 , A61M5/31533 , A61M2005/3206 , A61M2005/3208 , A61M2207/10 , Y10T29/49822 , Y10T29/53
摘要： A removal device (121, 221) for removing and disposing of a pen needle (113, 213) connectable to a drug delivery device (111, 211) includes a body (123, 223) having a cavity (141, 241) for receiving the pen needle of the drug delivery device such that a patient end (116, 216) of a needle (115, 215) of the pen needle is covered by the body. An ejector (151, 251) is movably connected to the body (123, 223) for engaging the received pen needle (113, 213) and selectively ejecting the engaged pen needle from the body. The pen needle (113, 213) is securely retained within the removal device (121, 221) without exposing the needle (115, 215) of the pen needle until the pen needle (113, 213) can be properly disposed of, such as in a sharps container, thereby substantially preventing an accidental needle stick.
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公开(公告)号：US12067438B2
公开(公告)日：2024-08-20
申请号：US17922101
申请日：2021-11-01
发明人： Alfred Leibbrand , Nicolas Euvrard , Cédric Rivier , Gwenn Le Dimet , Damien Maréchal , Thierry Vasquez
IPC分类号： G06K19/07
CPC分类号： G06K19/0723
摘要： A tip cap assembly for coupling with a syringe body includes a luer lock adaptor, a rigid cap coupled to the luer lock adaptor; a rigid tip cap having distal end and proximal ends, the rigid tip cap being disposed at least partially within the rigid cap, a RFID tag positioned over the distal end of the tip cap, and an adhesive layer formed over the RFID tag. Also provided is RFID inlay for use with medical devices including a meshed substrate, and a RFID antenna and integrated circuit assembly adhered to the meshed substrate. A syringe and label assembly is disclosed, including a body having distal and proximal ends, a tip cap assembly having distal end and proximal ends, and a label at least partially surrounding the distal end of the syringe body and the proximal end of the tip cap, the label comprises an integrated RFID tag.
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公开(公告)号：US12060607B2
公开(公告)日：2024-08-13
申请号：US16846133
申请日：2020-04-10
发明人： Stephen P. A. Fodor , Glenn K. Fu
IPC分类号： C12Q1/6874 , C12N15/10 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686 , C12Q1/6869 , C12Q1/6876 , G16B25/00 , G16B25/20 , G16B30/00 , G16B25/10
CPC分类号： C12Q1/6874 , C12N15/1065 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686 , C12Q1/6869 , C12Q1/6876 , G16B25/00 , G16B25/20 , G16B30/00 , G16B25/10 , C12Q1/6809 , C12Q2565/102 , C12Q2537/157 , C12Q2525/191
摘要： Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical molecules by attachment of a diverse set of labels. Each copy of a molecule randomly chooses from a non-depleting reservoir of diverse labels. Detection may be by a variety of methods including hybridization based or sequencing. Molecules that would otherwise be identical in information content can be labeled to create a separately detectable product that is unique or approximately unique in a collection. This stochastic transformation relaxes the problem of counting molecules from one of locating and identifying identical molecules to a series of binary digital questions detecting whether preprogrammed labels are present. The methods may be used, for example, to estimate the number of separate molecules of a given type or types within a sample.
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