摘要:
Disclosed are: a novel compound which has both an antagonistic activity on an angiotensin II receptor and a PPARγ-activating activity and is therefore useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, arteriosclerosis, type-2 diabetes, diabetic complications, metabolic syndrome or the like; and a pharmaceutical composition containing the compound. Specifically disclosed are: a compound represented by general formula (I) (wherein the ring A represents a pyridine ring; the ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—R5 or a nitrogen atom; R1 represents a C1-6 alkyl group; R2 represents a C1-6 alkyl group or a C3-8 cycloalkyl group; and R3, R4, R5 independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group, a halo-C1-6 alkyl group, or a C1-6 alkoxy group which may have a substituent), a salt of the compound, or a solvate of the compound or the salt; and a pharmaceutical composition containing the compound, the salt or the solvate.
摘要:
The present invention provides a low molecular weight compound having EPO production-promoting action and/or hemoglobin production-promoting action. The present invention relates to a fused piperidine compound represented by the following general formula (1): (wherein, ring A represents a C10-14 aryl group or 5- to 10-membered heterocyclic group, X represents N—R7, a sulfur atom or an oxygen atom, R1, R2, R2′, R3 and R3′ independently represent a hydrogen atom, C1-6 alkyl group or C3-6 cycloalkyl group, and R4, R5 and R6 independently represent a hydrogen atom or halogen atom), or a salt thereof, or a solvate thereof.
摘要:
An ignition element mounting capacitor having an ignition element mounted on a capacitor, includes therein a first capacitor section and a second capacitor section, and first external terminal electrodes electrically connected to the first capacitor section and second external terminal electrodes electrically connected to the second capacitor section. The first capacitor section has a capacity for igniting ignition powder, and the second capacitor section has a function for removing noise which affects external circuits. Further, provided on the surface of the capacitor are third external terminal electrodes electrically connected to the ignition element. In this manner, the invention provides a squib enabling its size to be miniaturized and its quality to be improved, while keeping a high productivity, and hence provides a header assembly and a ignition element mounting capacitor as components of the squib and further provides a gas generator having such a squib installed therein for an air bag and a gas generator having the squib for a seat belt pretensioner.
摘要:
To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.
摘要:
There is provided an IP broadcast receiver apparatus capable of, even when the input of a stream is delayed, determining whether a stream is to be inputted later and displaying a picture when a stream is inputted. When the content providing side makes a request to set a streamstatus attribute to “play” in a display using BML, the IP broadcast receiver apparatus determines whether channel information has been acquired from an IP broadcast server. The IP broadcast receiver apparatus sets the streamstatus attribute to “play” if channel information has been acquired from the IP broadcast server and sets the streamstatus attribute to “stop” if channel information has not been acquired from the IP broadcast server.
摘要:
An operation device for a vehicle is provided that enables switching over of a plurality of operation menu display screens and switching over of a plurality of function display screens for in-vehicle equipment displayed on a monitor by tilting of an operating knob (30) in eight directions, pivoting of the operating knob (30) around its axis, and operation of a main switch (31) and a sub switch (32) provided on the operating knob (30). In this process, since the operating knob (30) is not pivoted around its axis without limit but it is restricted so that pivoting is possible only in a predetermined angle range, it is not necessary to change the grip on the operating knob (30) when pivoting the operating knob (30), the burden on the wrist is lessened, and the operability is improved. Moreover, since the main switch (31) and the sub switch (32) are provided on the operating knob (20), they can be operated without detaching the hand from the operating knob (30), thus further improving the operability.
摘要:
An interface device (15) is provided that includes an operating knob (30) for outputting an operation command signal to in-vehicle equipment, the operating knob (30) being provided with a palm rest portion (30a) for an occupant's palm to be placed on, and a switch (31) being disposed on the operating knob (30) within a region that a fingertip can reach while the palm is placed on the palm rest portion (30a). Since this determines the positional relationship between the switch (31) and the fingertip when the palm is placed on the palm rest portion (30a), even if the switch (31) is operated without being visually checked it is possible to prevent an erroneous operation from occurring and, moreover, the operability is remarkably improved. Furthermore, since tilting the operating knob (30), which is supported so that it can tilt in fore-and-aft and left-and-right directions, outputs an operation command signal to in-vehicle equipment, coupling this with operation of the switch (31) enables many types of operation command signal to be outputted.
摘要:
An ignition element mounting capacitor having an ignition element mounted on a capacitor, includes therein a first capacitor section and a second capacitor section, and first external terminal electrodes electrically connected to the first capacitor section and second external terminal electrodes electrically connected to the second capacitor section. The first capacitor section has a capacity for igniting ignition powder, and the second capacitor section has a function for removing noise which affects external circuits. Further, provided on the surface of the capacitor are third external terminal electrodes electrically connected to the ignition element. In this manner, the invention provides a squib enabling its size to be miniaturized and its quality to be improved, while keeping a high productivity, and hence provides a header assembly and a ignition element mounting capacitor as components of the squib and further provides a gas generator having such a squib installed therein for an air bag and a gas generator having the squib for a seat belt pretensioner.
摘要:
An infrared sensor includes a first substrate made of a thermoelectric conversion material and a second substrate. The first substrate is supported by posts made of an electrode material while being spaced apart from the second substrate. A sensing electrode and lead portions connected thereto are provided on the first substrate. The sensing electrode and the lead portions are covered with an infrared-absorbing film. The posts are connected to the lead portions, and external terminal connection electrodes are connected to the posts.
摘要:
A piezoelectric thin film resonator that ensures the strength of a membrane without degrading the resonant properties and which can be easily handled in mounting. The piezoelectric thin film resonator has a substrate, a thin film member, and reinforcing films. The thin film member has at least two support portions supported by the substrate and a floating portion disposed over the substrate with a space provided therebetween and supported by the support portions. The floating portion includes a pair of excitation electrodes facing each other and a piezoelectric thin film provided therebetween. The reinforcing films are formed in the vicinities of the boundaries between the floating portion and the support portions of the thin film member.