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21.
公开(公告)号:US20170336534A1
公开(公告)日:2017-11-23
申请号:US15600020
申请日:2017-05-19
Applicant: THE CATHOLIC UNIVERSITY OF AMERICA
Inventor: Kevin F. Forbes , Ernest M. Zampelli
CPC classification number: G01W1/10 , F05B2260/8211 , G01W2001/006 , G01W2201/00 , G01W2203/00 , G06F16/23 , G06F17/10 , G06F17/18 , G06N20/00 , G06Q10/04 , G06Q50/06
Abstract: A computer system and method for improving the accuracy of predictions of the amount of renewable energy, such as solar energy and wind energy, available to an electric utility, and/or refine such predictions, by providing improved integration of meteorological forecasts. Coefficient values are calculated for a renewable energy generation model by performing a regression analysis with the forecasted level of renewable energy posted by the utility, forecasted weather conditions and measures of seasonality as explanatory variables. Accuracy is further enhanced through the inclusion of a large number of time series variables that reflect the systematic nature of the energy/weather system. The model also uses the original forecast posted by the system operator as well as variables to control for season.
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公开(公告)号:US20170334779A1
公开(公告)日:2017-11-23
申请号:US15597227
申请日:2017-05-17
Applicant: The Catholic University of America
Inventor: Weiliang GONG , Hui XU , Werner LUTZE , Ian PEGG
IPC: C04B28/00 , C04B22/08 , C04B24/26 , C09K8/42 , E21B33/14 , C04B22/06 , C04B14/22 , C04B103/22 , C04B103/12 , C04B103/32 , C04B111/00
CPC classification number: C04B28/006 , C04B14/22 , C04B22/062 , C04B22/08 , C04B24/26 , C04B2103/12 , C04B2103/22 , C04B2103/32 , C04B2111/00146 , C09K8/42 , C09K8/467 , E21B33/14 , Y02P40/165 , Y02W30/92 , Y02W30/94 , Y02W30/95 , C04B12/04 , C04B18/08 , C04B2103/24 , C04B14/047 , C04B14/062 , C04B14/106 , C04B14/14 , C04B14/18 , C04B18/141 , C04B18/146 , C04B18/162 , C04B22/066 , C04B22/008
Abstract: Three pumpable geopolymer compositions for well sealing application is disclosed herein. One pumpable geopolymer composition comprises: (i) less reactive aluminosilicate; (ii) more reactive aluminosilicate; (iii) alkaline silicate activator solution with a very low SiO2/M2O. Another pumpable geopolymer composition comprises: (i) less reactive aluminosilicate; (ii) more reactive aluminosilicate; (iii) alkaline silicate-free activator solution that may contain an alkali salt; and (iv) powdered alkali silicate glass. The third pumpable geopolymer composition comprises (i) less reactive aluminosilicate; (ii) more reactive aluminosilicate; (iii) alkaline low silicate activator solution; and (iv) powdered alkali silicate glass.
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23.
公开(公告)号:US20140329891A1
公开(公告)日:2014-11-06
申请号:US14337545
申请日:2014-07-22
Applicant: The Catholic University of America
Inventor: Venigalla B. RAO
IPC: C12N15/85
CPC classification number: C12N15/87 , C07K2319/10 , C07K2319/40 , C07K2319/61 , C12N2795/10122 , C12N2795/10123 , C12N2795/10142 , C12N2810/6009 , C12N2810/85 , C12N2810/859
Abstract: Described is T4 DNA packaging machine comprising: one or more DNA molecules packaged in a head of the T4 DNA packaging machine, one or more Hoc-fused proteins displayed on the head of the T4 DNA packaging machine, and one or more Soc-fused proteins displayed on the head of the T4 DNA packaging machine. Also described are methods of making and using such a T4 DNA packaging machine.
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24.
公开(公告)号:US20010044643A1
公开(公告)日:2001-11-22
申请号:US09737546
申请日:2000-12-18
Applicant: The Catholic University of America
Inventor: Theodore A. Litovitz
IPC: A61N001/00
Abstract: Methods and apparatus are described for the treatment of diseases by exposures to electromagnetic fields. Also, apparatus is described for focusing the biological effectiveness of such fields on specific cells, tissues or organs of a human or animal body.
Abstract translation: 描述了通过暴露于电磁场来治疗疾病的方法和装置。 此外,描述了将这些领域的生物学效力聚焦在人或动物体的特定细胞,组织或器官上的装置。
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公开(公告)号:US12037597B2
公开(公告)日:2024-07-16
申请号:US17488542
申请日:2021-09-29
Applicant: The Catholic University of America
Inventor: Venigalla B. Rao , Jingen Zhu
IPC: C12N15/86
CPC classification number: C12N15/86 , C12N2750/14133 , C12N2750/14134 , C12N2795/10133 , C12N2795/10134
Abstract: Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector.
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公开(公告)号:US20210054410A1
公开(公告)日:2021-02-25
申请号:US16990289
申请日:2020-08-11
Applicant: The Catholic University of America
Inventor: Venigalla B. RAO , Jingen ZHU
IPC: C12N15/86
Abstract: Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector.
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27.
公开(公告)号:US20200147207A1
公开(公告)日:2020-05-14
申请号:US16722124
申请日:2019-12-20
Applicant: The Catholic University of America
Inventor: Venigalla B. RAO
IPC: A61K39/295 , A61K39/02 , C07K19/00 , A61K39/07 , A61K39/385 , C07K14/005 , C07K14/32 , C07K14/24
Abstract: Bivalent immunogenic compositions against anthrax and plague are disclosed herein. One bivalent immunogenic composition comprises a triple fusion protein containing three antigens, F1 and V from Yersinia pestis and PA antigen from Bacillus anthracis fused in-frame and retaining structural and functional integrity of all three antigens. Another bivalent immunogenic composition comprises bacteriophage nanoparticles arrayed with these three antigens on the capsid surface of the bacteriophage nanoparticles. These bivalent immunogenic compositions are able to elicit robust immune response in a subject administered said the bivalent immunogenic compositions and provide protection to the subject against sequential or simultaneous challenge with both anthrax and plague pathogens.
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28.
公开(公告)号:US20180264102A1
公开(公告)日:2018-09-20
申请号:US15892772
申请日:2018-02-09
Applicant: The Catholic University of America
Inventor: Venigalla B. RAO
IPC: A61K39/295 , C07K19/00 , C07K14/24 , C07K14/32 , C07K14/005 , A61K39/385 , A61K39/07
Abstract: Bivalent immunogenic compositions against anthrax and plague are disclosed herein. One bivalent immunogenic composition comprises a triple fusion protein containing three antigens, F1 and V from Yersinia pestis and PA antigen from Bacillus anthracia fused in-frame and retaining structural and functional integrity of all three antigens. Another bivalent immunogenic composition comprises bacteriophage nanoparticles arrayed with these three antigens on the capsid surface of the bacteriophage nanoparticles. These bivalent immunogenic compositions are able to elicit robust immune response in a subject administered said the bivalent immunogenic compositions and provide protection to the subject against sequential or simultaneous challenge with both anthrax and plague pathogens.
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公开(公告)号:US09944679B2
公开(公告)日:2018-04-17
申请号:US14806751
申请日:2015-07-23
Applicant: THE CATHOLIC UNIVERSITY OF AMERICA
Inventor: Venigalla B. Rao , Wadad Alsalmi
IPC: C07K14/16 , C07K14/005 , C12N7/00 , A61K9/70 , A61K39/21 , C07K1/22 , C07K1/36 , A61K39/12 , A61K39/00
CPC classification number: C07K14/005 , A61K9/7023 , A61K39/00 , A61K39/12 , A61K39/21 , A61K2039/54 , A61K2039/627 , C07K1/22 , C07K1/36 , C07K14/162 , C07K2319/00 , C07K2319/20 , C07K2319/21 , C07K2319/22 , C07K2319/40 , C07K2319/50 , C12N7/00 , C12N2740/16022 , C12N2740/16043 , C12N2740/16051 , C12N2740/16111 , C12N2740/16122 , C12N2740/16134 , C12N2740/16234
Abstract: Provided herein are HIV vaccines that encompasses recombinant trimers that mimic native HIV-1 envelope trimers. Also provided are methods of administering to a subject in need thereof an HIV vaccine provided herein to elicit antibodies against a recombinant trimer in the subject. A recombinant trimer is formed by a recombinant protein comprising a recombinant HIV-1 gp140 fused to a tag through a linker at C-terminus of the recombinant HIV-1 gp140, wherein the linker is sufficiently long so that the tag is accessible for binding by a binding molecule bound on a solid matrix during purification of the recombinant trimer.
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公开(公告)号:US09919974B2
公开(公告)日:2018-03-20
申请号:US14193001
申请日:2014-02-28
Applicant: The Catholic University of America
Inventor: Weiliang Gong , Werner Lutze , Ian L. Pegg
CPC classification number: C04B38/02 , C04B28/006 , Y02P40/165 , Y02W30/92 , Y02W30/94 , Y02W30/95 , C04B12/04 , C04B14/06 , C04B14/106 , C04B14/28 , C04B14/303 , C04B18/08 , C04B18/141 , C04B18/162 , C04B20/002 , C04B20/0048 , C04B20/008 , C04B22/04 , C04B22/06 , C04B38/08 , C04B2103/0088 , C04B2103/22 , C04B2103/58
Abstract: A composite binder comprises: one or more Class F fly ash materials, one or more gelation enhancers, and one or more hardening enhancers, wherein each of the one or more Class F fly ash materials comprises 15 wt. % or less calcium oxide, and wherein the composite binder is a Portland cement-free binder for concrete. Also provided are Geopolymer Composite Cellular Concretes (GCCCs) including the composite binder and methods of making these GCCCs.
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