公开(公告)号：US20160060492A1

公开(公告)日：2016-03-03

申请号：US14474958

申请日：2014-09-02

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ying Zhang ,  Albert I. Everaerts ,  Corrine Lipscomb

IPC: C09J133/08 ,  C08K5/11 ,  C08K5/50 ,  C08K5/07 ,  C08K5/13 ,  C08K5/01 ,  C08K5/05 ,  B32B37/12 ,  C08K5/09

CPC classification number: C08K5/07 ,  B32B37/12 ,  B32B2457/00 ,  C08G18/6225 ,  C08G18/6229 ,  C08G18/792 ,  C08K5/01 ,  C08K5/05 ,  C08K5/09 ,  C08K5/11 ,  C08K5/13 ,  C08K5/50 ,  C08K5/5435 ,  C09J11/06 ,  C09J133/066 ,  C09J175/04 ,  H01B1/22 ,  C08F2220/1858 ,  C08F2220/1875 ,  C08F220/20

Abstract: The present invention is an adhesive composition for stabilizing an electrical conductor. The adhesive composition includes a base polymer and an additive to interfere with photo-oxidation of metals. When the adhesive composition is in contact with the electrical conductor, the electrical conductor has less than about a 20% change in electrical resistance over a period of about 500 hours of light exposure.

Abstract translation: 本发明是用于稳定电导体的粘合剂组合物。 粘合剂组合物包括基础聚合物和用于干扰金属光氧化的添加剂。 当粘合剂组合物与电导体接触时，电导体在约500小时的曝光时间内具有小于约20％的电阻变化。

公开(公告)号：US20140343499A1

公开(公告)日：2014-11-20

申请号：US14361787

申请日：2012-11-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ying Zhang ,  Percy T. Fenn ,  Peter R. Johnson

IPC: A61K38/29 ,  A61K9/00 ,  A61M37/00

CPC classification number: A61K9/0021 ,  A61K9/0087 ,  A61K31/198 ,  A61K31/4172 ,  A61K38/225 ,  A61K38/23 ,  A61K38/28 ,  A61K38/29 ,  A61K38/47 ,  A61K47/183 ,  A61K47/22 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/214 ,  A61L2300/252 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  C12Y302/01007 ,  A61K2300/00

Abstract: A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.

Abstract translation: 公开了一种包括微针阵列和设置在微针上或其内的涂层的医疗装置和制造这种装置的方法。 该涂层包括肽治疗剂和氨基酸。 还公开了在微针阵列上用氨基酸稳定肽治疗剂的方法。 在一些情况下，肽治疗剂和氨基酸都具有净正电荷或两者具有净负电荷。 在一些情况下，肽治疗剂是组氨酸。

公开(公告)号：US20140046293A1

公开(公告)日：2014-02-13

申请号：US13791360

申请日：2013-03-08

Applicant: Radius Health, Inc. ,  3M Innovative Properties Company, a wholly owned subsidiary of 3M Company

Inventor： Gary Hattersley ,  Kris J. Hansen ,  Amy S. Determan ,  Ying Zhang

IPC: A61K38/29 ,  A61K9/00

Abstract: The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu22,25, Leu23,28,31, Aib29, Lys26,30]hPTHrP(1-34)NH2.

Abstract translation: 本发明提供了与皮内递送PTHrP和PTHrP类似物，特别是[Glu22,25，Leu23,28,31，Aib29，Lys26,30] hPTHrP（1-34）NH2相关的组合物，装置，方法和方法。

公开(公告)号：US20250034387A1

公开(公告)日：2025-01-30

申请号：US18715465

申请日：2022-12-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Dillon S. Gentekos ,  Lili Qie ,  Kumars Sakizadeh ,  Michael D. Zenner ,  Ying Zhang

IPC: C08L33/06 ,  B05D1/02 ,  B05D5/10 ,  C08F2/26 ,  C08F220/18 ,  C09J5/00 ,  C09J7/10 ,  C09J7/38 ,  C09J133/06

Abstract: A composition includes an acrylic polymer, an emulsifier, and water. The acrylic polymer includes monomer units of at least one alkyl acrylate or alkyl methacrylate, wherein alkyl has at least 8 carbon atoms. Not more than one percent by weight of monomer units include a carboxylic acid, sulfonic acid, or phosphonic acid, based on the total weight of monomer units in the acrylic polymer. The composition is an emulsion of the acrylic polymer in water. The composition is a spray adhesive composition and/or coagulates upon being subjected to shear forces. A process for making the composition and a method for making a bonded article using the composition are also described.

公开(公告)号：US11643494B2

公开(公告)日：2023-05-09

申请号：US17258231

申请日：2019-07-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Vasav Sahni ,  Saswata Chakraborty ,  Wayne S. Mahoney ,  Jason D. Clapper ,  Jacob P. Johnson ,  Ying Zhang ,  Albert I. Everaerts ,  Bryan V. Hunt ,  Richard B. Ross

IPC: C08F255/10 ,  C08L23/22 ,  C09J123/22 ,  C09J153/02

CPC classification number: C08F255/10 ,  C08L23/22 ,  C09J123/22 ,  C09J153/025 ,  C08L2205/03

Abstract: A composition is described comprising a styrene-isobutylene block copolymer; and at least one ethylenically unsaturated monomer. After curing the composition comprises polymerized units of the ethylenically unsaturated monomer. In some embodiments the ethylenically unsaturated groups are selected from (meth)acryl or vinyl ether. The composition is suitable for use as a (e.g. pressure sensitive) adhesive. Articles, methods of making an article, and methods of bonding are also described.

公开(公告)号：US20200095476A1

公开(公告)日：2020-03-26

申请号：US16483534

申请日：2018-03-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Vasav Sahni ,  Jason D. Clapper ,  Jacob P. Johnson ,  Ying Zhang

IPC: C09J7/38 ,  C09J7/40 ,  C09J11/06

Abstract: In one embodiment, an adhesive composition is described comprising a polyisobutylene polymer component, a styrene-isobutylene block copolymer, and optionally a tackifier. The polyisobutylene polymer component comprises one or more polyisobutylene polymers. The polyisobutylene polymer component has an average weight average molecular weight ranging from 15,000 g/mole to 300,000 g/mole. The weight ratio of block copolymer to polyisobutylene polymer of the adhesive composition is greater than 2.2:1. In some embodiments, the adhesive composition is a pressure sensitive adhesive.

公开(公告)号：US20140330198A1

公开(公告)日：2014-11-06

申请号：US14361802

申请日：2012-11-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ying Zhang ,  Percy T. Fenn ,  Peter R. Johnson

IPC: A61K47/22 ,  A61K47/18 ,  A61M37/00 ,  A61K38/28 ,  A61K38/47 ,  A61K38/29 ,  A61K38/22

CPC classification number: A61K9/0021 ,  A61K9/0087 ,  A61K31/198 ,  A61K31/4172 ,  A61K38/225 ,  A61K38/23 ,  A61K38/28 ,  A61K38/29 ,  A61K38/47 ,  A61K47/183 ,  A61K47/22 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/214 ,  A61L2300/252 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  C12Y302/01007 ,  A61K2300/00

Abstract: A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.

Abstract translation: 公开了一种包括微针阵列和设置在微针上或其内的涂层的医疗装置和制造这种装置的方法。 该涂层包括肽治疗剂和氨基酸。 还公开了在微针阵列上用氨基酸稳定肽治疗剂的方法。 在一些情况下，肽治疗剂和氨基酸都具有净正电荷或两者具有净负电荷。 在一些情况下，肽治疗剂是组氨酸。