公开(公告)号：US10465217B2

公开(公告)日：2019-11-05

申请号：US14901532

申请日：2015-06-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun Ah Kim ,  Ju Hee Seo ,  Yong Uk Shin ,  So Young Kim ,  Sang Kyoum Kim ,  Kwang Ho Na ,  Jee Yeon Bae ,  Sung Kwang Son ,  Hye Ryun Yoo ,  Jin Geun Choi

IPC: C12N1/21 ,  C12N15/54 ,  C12N15/53 ,  C12N15/60 ,  C12N9/10 ,  C12P13/06 ,  C12N9/12 ,  C12N9/88 ,  C12N15/52

Abstract: Disclosed is a microorganism of Escherichia sp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the microorganism.

公开(公告)号：US10400256B2

公开(公告)日：2019-09-03

申请号：US15579188

申请日：2016-06-03

Applicant: CJ Cheiljedang Corporation

Inventor： Jee Yeon Bae ,  Ji Hyun Shim ,  Hyun Ah Kim ,  Juhee Seo ,  Yong Uk Shin ,  Jae Hee Lee ,  Sang Kyoum Kim ,  So Young Kim

IPC: C12P13/06 ,  C12P13/12 ,  C12N15/70 ,  C07K14/245

Abstract: The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.

公开(公告)号：US10378031B2

公开(公告)日：2019-08-13

申请号：US15765577

申请日：2016-10-13

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Imsang Lee ,  Sung Kwang Son ,  Hyeryun Yoo ,  Jae Hee Lee ,  Joo Hee Lee ,  Jin Sook Chang ,  Jin-Geun Choi ,  So Young Kim ,  Yong Uk Shin

IPC: C12N9/10 ,  C12N15/70 ,  C12P13/12

Abstract: The present disclosure relates to a novel O-acetylhomoserine sulfhydrylase variant, a polynucleotide encoding the same, a vector comprising the polynucleotide, a strain capable of expressing the variant, and a method for producing L-methionine using the variant.

公开(公告)号：US09834491B2

公开(公告)日：2017-12-05

申请号：US14219307

申请日：2014-03-19

Applicant: CJ Cheiljedang Corporation

Inventor： Han Won Lee ,  Young Lyeol Yang ,  So Young Kim ,  Yong Uk Shin ,  Jin Sook Chang ,  Hye Won Um ,  Young Hyoung Goh ,  Sung Hoo Jhon

IPC: C07C1/24 ,  C07D307/22 ,  C07D307/20 ,  C07D307/08 ,  C07D207/12 ,  C07C29/09 ,  C07C29/149 ,  C07C29/48

CPC classification number: C07C1/24 ,  C07C29/09 ,  C07C29/149 ,  C07C29/48 ,  C07C2529/40 ,  C07D207/12 ,  C07D307/08 ,  C07D307/20 ,  C07D307/22 ,  C07C11/04 ,  C07C31/12 ,  C07C31/08 ,  C07C31/202

Abstract: The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence of an acid catalyst. According to the present invention, O-acyl homoserine produced by a microorganism is used as a raw material for producing 1,4-butanediol, gamma-butyrolactone, tetrahydrofuran and the like, which are industrially highly useful. The O-acyl homoserine produced by a microorganism can substitute conventional petrochemical products, can solve environmental concerns, including the emission of pollutants and the exhaustion of natural resources, and can be continuously renewable so as not to exhaust natural resources.

公开(公告)号：US20170016037A1

公开(公告)日：2017-01-19

申请号：US15282416

申请日：2016-09-30

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： So Young Kim ,  Yong Uk Shin ,  In Kyung Heo ,  Hyun Ah Kim ,  Ju Eun Kim ,  Chang Il Seo ,  Sung Kwang Son ,  Sang Mok Lee ,  Sung Hoo Jhon ,  Han Jin Lee ,  Kwang Ho Na ,  Il Chul Kim

IPC: C12P13/12 ,  A23L33/175 ,  A61K47/02 ,  A61K9/08 ,  A61K31/20

CPC classification number: C12P13/12 ,  A23L33/175 ,  A23V2002/00 ,  A61K9/08 ,  A61K31/20 ,  A61K47/02 ,  C07C319/26 ,  C07C323/52

Abstract: The present invention relates to a method for enhancing the solubility of methionine. More particularly, the present invention relates to a method for increasing the solubility of methionine, in which mineral and sulfuric acid are added at an appropriate ratio to enhance the methionine solubility, thereby overcoming the problem of low solubility of methionine in water.

Abstract translation: 本发明涉及提高甲硫氨酸溶解度的方法。 更具体地说，本发明涉及增加甲硫氨酸的溶解度的方法，其中以适当的比例加入矿物和硫酸以提高甲硫氨酸的溶解度，从而克服了蛋氨酸在水中溶解度低的问题。