摘要:
The present invention is directed to bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as scaffolds for tissue engineering.
摘要:
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof. The web materials possess hemostatic properties.
摘要:
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.
摘要:
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.
摘要:
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.
摘要:
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.
摘要:
The present invention is directed to a method of making implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.
摘要:
A conditional access network is provide that generates and captures authenticated events. These authenticated events are securely generated responsive to communications between the network and processors, where the processors are embedded in associated targets or products. Events may be, for example, receiving targets into inventory, shipping targets to another entity, activating targets at a point of sale, or permanently disabling a defective target. These authenticated events are captured by the network, and used to support transactions. For example, the timely and trustworthy information derived from the authenticated events can be used to support financial, ownership, or regulatory transactions. In one use, the authenticated events enable a consignment business model where the distributor, retailer, and products all participate in the conditional access network. With the timely and accurate inventory, sales, and return information provided by the authenticated events, disputes over settlement are dramatically reduced.
摘要:
A system is provided for authenticating and securing product transactions. An integrated circuit is attached to a target, such as an optical disc or electronic device. The integrated circuit has an RF transceiver that is capable of establishing communication with an associated reading device. The integrated circuit also has a hidden memory, which can not be read externally, and a user memory. The hidden memory stores an authentication message, while the user memory stores readable authentication information. The hidden authentication message and the authentication information are related through a cryptographic process. However, even though the integrated circuit benefits from the cryptographic security, the integrated circuit only operates relatively simple logic operations. In this way, a highly secure transaction is enabled without requiring significant processing power or time at the integrated circuit. When the integrated circuit is placed near the reader, the reader reads the authentication information, and with the cooperation of a network operation center, uses the authentication information to derive an activation code. The reader passes the activation code to the integrated circuit, which compares the activation code to its hidden activation message. If they have a proper relationship, the communication has been authenticated, and the integrated circuit proceeds to perform an action.
摘要:
A method of treatment of a disease of the human or animal body mediated by PARP comprising administering to such a subject a therapeutically effective amount of a compound of formula: or an isomer, salt, solvate, chemically protected form, and prodrug thereof, wherein: A and B together represent an optionally substituted, fused aromatic ring; RC is represented by -L-RL, where L is of formula: —(CH2)n1-Qn2-(CH2)n3— wherein n1, n2 and n3 are each selected from 0, 1, 2 and 3, the sum of n1, n2 and n3 is 1, 2 or 3 and Q is selected from O, S, NH, C(═O) or —CR1R2—, where R1 and R2 are independently selected from hydrogen, halogen or optionally substituted C1-7 alkyl, or may together with the carbon atom to which they are attached form a C3-7 cyclic alkyl group, which may be saturated (a C3-7 cycloalkyl group) or unsaturated (a C3-7 cycloalkenyl group), or one of R1 and R2 may be attached to an atom in RL to form an unsaturated C3-7 cycloalkenyl group which comprises the carbon atoms to which R1 and R2 are attached in Q, —(CH2)n3— (if present) and part of RL; and RL is optionally substituted C5-20 aryl; and RN is selected from hydrogen, optionally substituted C1-7 alkyl, C3-20 heterocyclyl, and C5-20 aryl, hydroxy, ether, nitro, amino, amido, thiol, thioether, sulfoxide and sulfone.