Recombinant hexose oxidase
    23.
    发明授权
    Recombinant hexose oxidase 有权
    重组己糖氧化酶

    公开(公告)号:US08178090B2

    公开(公告)日:2012-05-15

    申请号:US12396954

    申请日:2009-03-03

    CPC分类号: C12N9/0006 A01N63/00

    摘要: Use of a preparation as an antimicrobial agent or as an anti-oxidant; wherein said preparation comprises a polypeptide having hexose oxidase activity, the polypeptide being in a substantially pure form, and said polypeptide comprises at least one amino acid sequence selected from the group consisting of (i)(SEQ ID NO: 1) Tyr-Glu-Pro-Tyr-Gly-Gly-Val-Pro (ii)(SEQ ID NO: 2) Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly- Tyr-Asp-X-X-X-Gly-Tyr-X-Val-Ser-Ser- (iii)(SEQ ID NO: 3) Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser- Asn-Leu-X-Phe- (iv)(SEQ ID NO: 4) Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His- Thr (v)(SEQ ID NO: 5) Tyr-Tyr-Phe-Lys (vi)(SEQ ID NO: 6) Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly- Thr-X-Asp (vii)(SEQ ID NO: 7) Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp (viii)(SEQ ID NO: 8) X-Ile-Arg-Asp-Phe-Tyr-Glu-Glu-Met where X represents an amino acid selected from the group consisting of Ala, Arg, Asn, Asp, Asx, Cys, Gln, Glu, Glx, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr and Val.

    摘要翻译: 使用制剂作为抗微生物剂或作为抗氧化剂; 其中所述制剂包含具有己糖氧化酶活性的多肽,所述多肽为基本上纯的形式,所述多肽包含至少一个选自下组的氨基酸序列:(i)(SEQ ID NO:1)Tyr-Glu- Pro-Tyr-Gly-Gly-Val-Pro(ii)(SEQ ID NO:2)Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly-Tyr-Asp-XXX -Gly-Tyr-X-Val-Ser-Ser-(iii)(SEQ ID NO:3)Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser-Asn-Leu -X-Phe-(iv)(SEQ ID NO:4)Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His-Thr(v)(SEQ ID NO: 5)Tyr-Tyr-Phe-Lys(vi)(SEQ ID NO:6)Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly-Thr-X-Asp )(SEQ ID NO:7)Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp(viii)(SEQ ID NO:8)X-Ile-Arg-Asp-Phe-Tyr -Glu-Glu-Met,其中X表示选自Ala,Arg,Asn,Asp,Asx,Cys,Gln,Glu,Glx,Gly,His,Ile,Leu,Lys,Met,Phe, Pro,Ser,Thr, Trp,Tyr和Val。