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    COMPOSITION
    4.
    发明申请
    COMPOSITION 审中-公开
    组成

    公开(公告)号：US20130224820A1

    公开(公告)日：2013-08-29

    申请号：US13452076

    申请日：2012-04-20

    申请人： Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    发明人： Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    IPC分类号： C12P3/00

    CPC分类号： A01N63/02 ,  C09D5/1606 ,  C12P3/00

    摘要： There is provided an anti-fouling composition comprising (i) a surface coating material; (ii) an enzyme obtained or obtainable from a marine organism; and (iii)(a) a substrate for the enzyme; and/or (b) a precursor enzyme and a precursor substrate, wherein the precursor enzyme and the precursor substrate are selected such that a substrate for the enzyme is generatable by action of the precursor enzyme on the precursor substrate; wherein the enzyme and the substrate are selected such that an anti-foulant compound is generatable by action of the enzyme on the substrate.

    摘要翻译： 提供了防污组合物，其包含（i）表面涂层材料; （ii）从海洋生物获得或可获得的酶; 和（iii）（a）酶的底物; 和/或（b）前体酶和前体底物，其中前体酶和前体底物被选择为使得酶的底物可以通过前体酶在前体基质上的作用产生; 其中选择酶和底物使得抗污垢化合物可通过酶在底物上的作用产生。

    Recombinant hexose oxidase
    5.
    发明授权
    Recombinant hexose oxidase 有权
    重组己糖氧化酶

    公开(公告)号：US08178090B2

    公开(公告)日：2012-05-15

    申请号：US12396954

    申请日：2009-03-03

    申请人： Peter Stougaard ,  Ole Cai Hansen ,  Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    发明人： Peter Stougaard ,  Ole Cai Hansen ,  Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    IPC分类号： A61K38/44 ,  A61K8/00 ,  A61K8/66 ,  C12N9/04 ,  A23K1/165 ,  A21D8/04 ,  C12N15/53 ,  C12N15/70 ,  C12N15/80

    CPC分类号： C12N9/0006 ,  A01N63/00

    摘要： Use of a preparation as an antimicrobial agent or as an anti-oxidant; wherein said preparation comprises a polypeptide having hexose oxidase activity, the polypeptide being in a substantially pure form, and said polypeptide comprises at least one amino acid sequence selected from the group consisting of (i)(SEQ ID NO: 1) Tyr-Glu-Pro-Tyr-Gly-Gly-Val-Pro (ii)(SEQ ID NO: 2) Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly- Tyr-Asp-X-X-X-Gly-Tyr-X-Val-Ser-Ser- (iii)(SEQ ID NO: 3) Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser- Asn-Leu-X-Phe- (iv)(SEQ ID NO: 4) Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His- Thr (v)(SEQ ID NO: 5) Tyr-Tyr-Phe-Lys (vi)(SEQ ID NO: 6) Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly- Thr-X-Asp (vii)(SEQ ID NO: 7) Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp (viii)(SEQ ID NO: 8) X-Ile-Arg-Asp-Phe-Tyr-Glu-Glu-Met where X represents an amino acid selected from the group consisting of Ala, Arg, Asn, Asp, Asx, Cys, Gln, Glu, Glx, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr and Val.

    摘要翻译： 使用制剂作为抗微生物剂或作为抗氧化剂; 其中所述制剂包含具有己糖氧化酶活性的多肽，所述多肽为基本上纯的形式，所述多肽包含至少一个选自下组的氨基酸序列：（i）（SEQ ID NO：1）Tyr-Glu- Pro-Tyr-Gly-Gly-Val-Pro（ii）（SEQ ID NO：2）Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly-Tyr-Asp-XXX -Gly-Tyr-X-Val-Ser-Ser-（iii）（SEQ ID NO：3）Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser-Asn-Leu -X-Phe-（iv）（SEQ ID NO：4）Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His-Thr（v）（SEQ ID NO： 5）Tyr-Tyr-Phe-Lys（vi）（SEQ ID NO：6）Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly-Thr-X-Asp ）（SEQ ID NO：7）Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp（viii）（SEQ ID NO：8）X-Ile-Arg-Asp-Phe-Tyr -Glu-Glu-Met，其中X表示选自Ala，Arg，Asn，Asp，Asx，Cys，Gln，Glu，Glx，Gly，His，Ile，Leu，Lys，Met，Phe， Pro，Ser，Thr， Trp，Tyr和Val。

    Recombinant hexose oxidase
    6.
    发明申请
    Recombinant hexose oxidase 有权
    重组己糖氧化酶

    公开(公告)号：US20090275103A1

    公开(公告)日：2009-11-05

    申请号：US12396954

    申请日：2009-03-03

    申请人： Peter Stougaard ,  Ole Cai Hansen ,  Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    发明人： Peter Stougaard ,  Ole Cai Hansen ,  Charlotte Horsmans Poulsen ,  Karsten Matthias Kragh

    IPC分类号： C12N9/04

    CPC分类号： C12N9/0006 ,  A01N63/00

    摘要： Use of a preparation as an antimicrobial agent or as an anti-oxidant; wherein said preparation comprises a polypeptide having hexose oxidase activity, the polypeptide being in a substantially pure form, and said polypeptide comprises at least one amino acid sequence selected from the group consisting of (i) (SEQ ID NO: 1) Tyr-Glu-Pro-Tyr-Gly-Gly-Val-Pro (ii) (SEQ ID NO: 2) Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly- Tyr-Asp-X-X-X-Gly-Tyr-X-Val-Ser-Ser- (iii) (SEQ ID NO: 3) Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser- Asn-Leu-X-Phe- (iv) (SEQ ID NO: 4) Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His- Thr (v) (SEQ ID NO: 5) Tyr-Tyr-Phe-Lys (vi) (SEQ ID NO: 6) Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly- Thr-X-Asp (vii) (SEQ ID NO: 7) Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp (viii) (SEQ ID NO: 8) X-Ile-Arg-Asp-Phe-Tyr-Glu-Glu-Met where X represents an amino acid selected from the group consisting of Ala, Arg, Asn, Asp, Asx, Cys, Gln, Glu, Glx, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr and Val.

    摘要翻译： 使用制剂作为抗微生物剂或作为抗氧化剂; 其中所述制剂包含具有己糖氧化酶活性的多肽，所述多肽为基本上纯的形式，所述多肽包含至少一个选自下组的氨基酸序列：（i）（SEQ ID NO：1）Tyr-Glu- Pro-Tyr-Gly-Gly-Val-Pro（ii）（SEQ ID NO：2）Ala-Ile-Ile-Asn-Val-Thr-Gly-Leu-Val-Glu-Ser-Gly-Tyr-Asp-XXX -Gly-Tyr-X-Val-Ser-Ser-（iii）（SEQ ID NO：3）Asp-Leu-Pro-Met-Ser-Pro-Arg-Gly-Val-Ile-Ala-Ser-Asn-Leu -X-Phe-（iv）（SEQ ID NO：4）Asp-Ser-Glu-Gly-Asn-Asp-Gly-Glu-Leu-Phe-X-Ala-His-Thr（v）（SEQ ID NO： 5）Tyr-Tyr-Phe-Lys（vi）（SEQ ID NO：6）Asp-Pro-Gly-Tyr-Ile-Val-Ile-Asp-Val-Asn-Ala-Gly-Thr-X-Asp ）（SEQ ID NO：7）Leu-Gln-Tyr-Gln-Thr-Tyr-Trp-Gln-Glu-Glu-Asp（viii）（SEQ ID NO：8）X-Ile-Arg-Asp-Phe-Tyr -Glu-Glu-Met，其中X表示选自Ala，Arg，Asn，Asp，Asx，Cys，Gln，Glu，Glx，Gly，His，Ile，Leu，Lys，Met，Phe， Pro，Ser，Thr，Trp，Tyr和Val。