EMULSIONS CONTAINING ARYLBORONIC ACIDS AND MEDICAL ARTICLES MADE THEREFROM
    25.
    发明申请
    EMULSIONS CONTAINING ARYLBORONIC ACIDS AND MEDICAL ARTICLES MADE THEREFROM 失效
    含有ARYLBONONIC酸的乳液及其制品

    公开(公告)号:US20110076337A1

    公开(公告)日:2011-03-31

    申请号:US12894983

    申请日:2010-09-30

    IPC分类号: A61K9/107 A61K47/36

    摘要: The invention provides emulsion compositions that include a hydrophobic compound and an arylboronic acid. An exemplary emulsion comprises a hydrophobic polymer and a halogenated arylboronic acid. Use of an arylboronic acid provides the emulsion with exceptional stability. The stability provides advantages for the formation of articles formed from the emulsion, including microparticles, as well as other implantable or injectable medical articles having polymeric matrices.

    摘要翻译: 本发明提供了包含疏水化合物和芳基硼​​酸的乳液组合物。 示例性的乳液包含疏水性聚合物和卤代芳基硼酸。 使用芳基硼酸提供了非常稳定的乳液。 稳定性为形成由乳液形成的制品提供了优点,包括微粒,以及具有聚合物基质的其它可植入或可注射的医疗制品。

    LIGAND-COUPLED INITIATOR POLYMERS AND METHODS OF USE
    26.
    发明申请
    LIGAND-COUPLED INITIATOR POLYMERS AND METHODS OF USE 审中-公开
    配体联合发射体聚合物及其使用方法

    公开(公告)号:US20110040057A1

    公开(公告)日:2011-02-17

    申请号:US12911578

    申请日:2010-10-25

    摘要: Initiator polymers having an initiator group and a ligand group are provided. The initiator polymers are capable of specifically binding to a receptor on a surface. Using a macromer system, the initiator polymers are useful for the formation of a polymeric matrix on the surface of a material. In particular, initiator polymers are provided that have specificity to pancreatic β cells and can be used to encapsulate cells for transplantation and the treatment of diabetes.

    摘要翻译: 提供了具有引发剂基团和配体基团的引发剂聚合物。 引发剂聚合物能够特异性结合表面上的受体。 使用大分子单体体系,引发剂聚合物可用于在材料表面上形成聚合物基质。 特别地,提供对胰腺特异性的引发剂聚合物; 细胞,可用于包封细胞进行移植和治疗糖尿病。

    Surface coating agents
    28.
    发明授权
    Surface coating agents 有权
    表面涂层剂

    公开(公告)号:US06603040B1

    公开(公告)日:2003-08-05

    申请号:US09888709

    申请日:2001-06-25

    申请人: Dale G. Swan

    发明人: Dale G. Swan

    IPC分类号: C07C30928

    摘要: Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule comprising an aromatic group; and Z comprises at least one charged group. The Y core can include an aromatic group such as a benzene radical, the charged groups Z can be independently selected from the organic acids that include sulfonic acid, carboxylic acid, and phosphoric acid, and the photoreactive species of X1 and X2 can independently be aryl ketones, such as those selected from the group acetophenone, benzophenone, anthraquinone, anthrone, and anthrone-like heterocycles, and their substituted derivatives. Examples of such coating agents include 4,5-bis(4-benzoylphenylmethyleneoxy) benzene-1,3-disulfonic acid di(potassium and/or sodium) salt, 2,5-bis(4-benzoylphenylmethyleneoxy) benzene-1,4-disulfonic acid di(potassium and/or sodium) salt (Compound II), and 2,5-bis(4-benzoylphenylmethyleneoxy) benzene-1-sulfonic acid monopotassium and/or monosodium salt.

    摘要翻译: 可用作表面包衣剂的化合物,包括下式的化合物:其中X1包含第一光反应性物质; X2包含第二光反应性物质; Y包含含有芳基的非聚合核心分子; Z包含至少一个带电基团。 Y芯可以包括苯基等芳基,带电基团Z可以独立地选自包括磺酸,羧酸和磷酸的有机酸,并且X1和X2的光反应性物质可以独立地为芳基 酮,例如选自苯乙酮,二苯甲酮,蒽醌,蒽酮和蒽酮类杂环的那些,及其取代的衍生物。 这种包衣剂的实例包括4,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1,3-二磺酸二(钾和/或钠)盐,2,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1,4- 盐(二盐酸盐)(化合物II)和2,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1-磺酸单钾盐和/或单钠盐。

    Surface coating agents
    29.
    发明授权
    Surface coating agents 有权
    表面涂层剂

    公开(公告)号:US06278018B1

    公开(公告)日:2001-08-21

    申请号:US09460551

    申请日:1999-12-14

    申请人: Dale G. Swan

    发明人: Dale G. Swan

    IPC分类号: C07C30928

    摘要: Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule comprising an aromatic group; and Z comprises at least one charged group. The Y core can include an aromatic group such as a benzene radical, the charged groups Z can be independently selected from the organic acids that include sulfonic acid, carboxylic acid, and phosphoric acid, and the photoreactive species of X1 and X2 can independently be aryl ketones, such as those selected from the group acetophenone, benzophenonie, anthraquinone, anthrone, and anthrone-like heterocycles, and their substituted derivatives. Examples of such coating agents include 4,5-bis(4-benzoylphenylmethyleneoxy) benzene-1,3-disulfonic acid di(potassium and/or sodium) salt, 2,5-bis(4-benzoylphenylmethyleneoxy)benzene-1,4-disulfonic acid di(potassium and/or sodium) salt (Compound II), and 2,5-bis(4-benzoylphenylmethyleneoxy)benzene-1-sulfonic acid monopotassium and/or monosodium salt.

    摘要翻译: 可用作表面包衣剂的化合物,包括下式的化合物:其中X1包含第一光反应性物质; X2包含第二光反应性物质; Y包含含有芳基的非聚合核心分子; Z包含至少一个带电基团。 Y芯可以包括苯基等芳基,带电基团Z可以独立地选自包括磺酸,羧酸和磷酸的有机酸,并且X1和X2的光反应性物质可以独立地为芳基 酮,例如选自苯乙酮,二苯甲酮,蒽醌,蒽酮和蒽酮类杂环的那些,及其取代的衍生物。 这种包衣剂的实例包括4,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1,3-二磺酸二(钾和/或钠)盐,2,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1,4- 盐(二盐酸盐)(化合物II)和2,5-双(4-苯甲酰基苯基亚甲基氧基)苯-1-磺酸单钾盐和/或单钠盐。

    Amino-poly(amidazoline-amide)
    30.
    发明授权
    Amino-poly(amidazoline-amide) 失效
    氨基聚(咪唑啉 - 酰胺)

    公开(公告)号:US4049598A

    公开(公告)日:1977-09-20

    申请号:US703035

    申请日:1976-07-06

    IPC分类号: C08G69/26 C08G69/34

    CPC分类号: C08G69/34 C08G69/265

    摘要: Amino-poly(imidazoline-amide) compositions are disclosed which are useful for occlusion in polyolefins to render them dyeable with acid textile dyes. Polyolefins are useful in textile fibers or filaments. The compositions are certain azelaic acid, polyamide-imidazoline products of a mixture of diethylene triamine and a diamine. Optionally, fatty compounds such as a dimeric fat acid or monomeric fatty acid or another, different aliphatic dicarboxylic acid may be present.

    摘要翻译: 公开了氨基 - 聚(咪唑啉 - 酰胺)组合物,其可用于聚烯烃中的封闭以使其可用酸性织物染料染色。 聚烯烃可用于纺织纤维或细丝。 组合物是二乙烯三胺和二胺的混合物的某些壬二酸,聚酰胺 - 咪唑啉产物。 任选地,可以存在脂肪化合物如二聚脂肪酸或单体脂肪酸或另一种不同的脂族二羧酸。