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21.发明申请BREAST IMPLANT WITH ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE 审中-公开具有对外部电源响应的分析仪传感器的乳腺植入物公开(公告)号：US20150327989A1
公开(公告)日：2015-11-19
申请号：US14809389
申请日：2015-07-27
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/076 , A61B5/14546 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2560/0219 , A61F2250/0085 , A61F2250/0096
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，多个传感器模块中的每一个被定向成检测与壳体相邻的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。
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公开(公告)号：US20140303660A1
公开(公告)日：2014-10-09
申请号：US13857038
申请日：2013-04-04
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
IPC: A61B17/32
CPC classification number: A61B17/32 , A61B17/32002 , A61B17/3211 , A61B34/75 , A61B90/90
Abstract: Described embodiments include a handheld or hand operated surgical instrument. The instrument includes an elongated member having a longitudinal axis and a handle portion. The instrument includes a working tip coupled to the elongated member. The instrument includes a sensor configured to detect a user-imparted hand tremble motion. The instrument includes a flexible beam element of the elongated member located in-between the handle portion and the working tip, and configured to reversibly bend, extend, or rotate with respect to the longitudinal axis. The instrument includes an actuator physically coupled to the flexible beam element and configured to reversibly bend, extend, or rotate the flexible beam element with respect to the longitudinal axis. The instrument includes a controller configured to stabilize the working tip by activating the actuator in a manner responsive to the detected user-imparted hand tremble motion in at least one degree of freedom.
Abstract translation: 所描述的实施例包括手持或手动手术器械。 仪器包括具有纵向轴线和手柄部分的细长构件。 仪器包括联接到细长构件的工作尖端。 该仪器包括被配置为检测用户传递的手颤动的传感器。 仪器包括位于手柄部分和工作尖端之间的细长构件的柔性梁元件，并且构造成相对于纵向轴线可逆地弯曲，延伸或旋转。 仪器包括物理地耦合到柔性梁元件并被配置为相对于纵向轴线可挠地弯曲，延伸或旋转柔性梁元件的致动器。 该仪器包括控制器，该控制器被配置为通过以至少一个自由度的方式响应于检测到的由用户传递的手颤动来激活致动器来稳定工作尖端。
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23.发明申请BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS AND INTERNAL POWER SOURCE 有权具有区域分析传感器和内部电源的BREAST植入物公开(公告)号：US20140296978A1
公开(公告)日：2014-10-02
申请号：US14301607
申请日：2014-06-11
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/076 , A61B5/14503 , A61B5/14507 , A61B5/14546 , A61B5/14735 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2560/0214 , A61B2560/0219 , A61B2560/0443 , A61B2562/028 , A61B2562/06 , A61B2562/162 , A61B2562/168 , G01N33/528 , G01N33/57415
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 多个传感器模块，其附接到所述壳体，所述传感器模块中的每一个被定向以检测所述多个隔室中的一个内的流体中的一种或多种分析物，其中所述多个传感器模块中的每一个包括唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。
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24.发明授权公开(公告)号：US08845739B2
公开(公告)日：2014-09-30
申请号：US13658982
申请日：2012-10-24
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61F2/30742 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30079 , A61F2002/30087 , A61F2002/30558 , A61F2002/30673 , A61F2002/30682 , A61F2002/30683 , A61F2002/3082 , A61F2002/3092 , A61F2002/3429 , A61F2002/3631 , A61F2002/482
Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo.
Abstract translation: 描述了假肢人工关节，包括髋关节，膝关节和肩关节。 在一些实施例中，人造关节假体包括：人造关节假体的面向骨的表面，所述面向对象的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 定位成邻近非接触表面定位的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转; 以及附接到所述流体偏转结构的机构，所述机构可操作以移动所述流体偏转结构以将滑液体在体内远离所述骨假体界面。
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25.发明授权公开(公告)号：US08795378B2
公开(公告)日：2014-08-05
申请号：US13629918
申请日：2012-09-28
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
IPC: A61F2/28
CPC classification number: A61F2/30 , A61F2/30742 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30079 , A61F2002/30087 , A61F2002/30558 , A61F2002/30673 , A61F2002/30682 , A61F2002/30683 , A61F2002/3082 , A61F2002/3092 , A61F2002/3429 , A61F2002/3631 , A61F2002/482
Abstract: Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid.
Abstract translation: 描述了人造关节假体，包括髋关节，膝关节和肩关节。 在一些方面，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨骼的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 连接到非接触表面的至少一个流体偏转结构，所述流体偏转结构被定位成在体内将滑液流引导离开骨假体界面; 以及至少一个颗粒保持结构，定位成接触滑液的定向流并被构造成保留存在于滑液内的颗粒。
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Patent Agency Ranking
26.发明申请公开(公告)号：US20140088718A1
公开(公告)日：2014-03-27
申请号：US13629918
申请日：2012-09-28
Applicant: ELWHA LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61F2/30742 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30079 , A61F2002/30087 , A61F2002/30558 , A61F2002/30673 , A61F2002/30682 , A61F2002/30683 , A61F2002/3082 , A61F2002/3092 , A61F2002/3429 , A61F2002/3631 , A61F2002/482
Abstract: Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid.
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公开(公告)号：US10780017B2
公开(公告)日：2020-09-22
申请号：US15406379
申请日：2017-01-13
Applicant: Elwha LLC
Inventor： Roderick A. Hyde , Kenneth G. Caldeira , Gary L. McKnight , Lowell L. Wood, Jr. , Dennis J. Rivet , Katherine A. Sharadin , Michael A. Smith
IPC: A61H9/00 , A61B5/0205 , A61M16/00 , A61B5/00 , A61B7/00 , A61F5/56 , A61B5/1455 , A61B5/08
Abstract: An embodiment of a system for treating sleep apnea includes a collar, a pump, a motor, a sensor, and a controller. The collar is configured to maintain an airway of a subject open while the subject is sleeping by applying, to a throat of the subject, a negative pressure having a magnitude, and the pump is configured to generate the negative pressure. The motor is configured to drive the pump, and the sensor is configured to generate a sense signal that is related to a degree to which the airway is open. And the controller is configured to vary the magnitude of the negative pressure in response to the sense signal. For example, one or more of the pump, motor, sensor, and controller can be secured to the collar such that the system is self-contained, i.e., the entire sleep-apnea system can be worn by the subject.
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公开(公告)号：US20200016435A1
公开(公告)日：2020-01-16
申请号：US16032623
申请日：2018-07-11
Applicant: ELWHA LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Jay Pierce , Katherine E. Sharadin , Michael A. Smith , Marc Stein , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR.
Abstract: A nerve modulation device includes a first ultrasound transducer and a second ultrasound transducer. The first and second ultrasound transducers are configured to emit a first and second ultrasound waves, respectively, that exhibit different frequencies. The first and second ultrasound transducers can emit the first and second ultrasound waves in directions that are selected to cause the first and second ultrasound waves to intersect with each other at an intersection site that is at or near a selected nerve. At the intersection site, the first and second ultrasound waves can non-linearly interact to form an acoustic wave exhibiting a frequency that is less than the frequencies of the first and second ultrasound waves. The acoustic wave can modulate a selected nerve.
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29.发明授权公开(公告)号：US09956531B2
公开(公告)日：2018-05-01
申请号：US14593110
申请日：2015-01-09
Applicant: Elwha LLC
Inventor： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC classification number: B01D67/0088 , A61M1/0088 , A61M1/1623 , A61M1/1631 , A61M2205/3334 , B01D69/12 , B01D2325/26
Abstract: A device and methods are disclosed herein for fluid removal during wound treatment or for removal or dialysis of components from blood or tissue. A device is disclosed that includes a multilayer membrane including a plurality of layers; an electroactive polymer within each layer; and a controller operably connected to sequentially activate the electroactive polymer to alter one or more sizes of the plurality of the variably-sized pores within one or more layers of the multilayer membrane. A device is disclosed that includes a multilayer membrane including a plurality of layers; an actuator operably attached to the plurality of layers of the multilayer membrane; and a controller operably activating the actuator to alter a relative lateral position of the two or more layers of the multilayer membrane to align two or more of the plurality of pores within the plurality of layers of the multilayer membrane.
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公开(公告)号：US20180090124A1
公开(公告)日：2018-03-29
申请号：US15683517
申请日：2017-08-22
Applicant: Elwha LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, JR.
CPC classification number: G10K11/345 , G10K11/34 , G10K11/343 , H04R1/40 , H04R2201/401
Abstract: The present disclosure provides systems and methods associated with acoustic transmitters, receivers, and antennas. Specifically, the present disclosure provides a transducer system for transmitting and receiving acoustic energy according to a determined acoustic emission/reception pattern. In various embodiments, an acoustic transducer system may include an array of sub-wavelength transducer elements each configured with an electromagnetic resonance at one of a plurality of electromagnetic frequencies. Each sub-wavelength transducer element may generate an acoustic emission in response to the electromagnetic resonance. A beam-forming controller may cause electromagnetic energy to be transmitted at select electromagnetic frequencies to cause a select subset of the sub-wavelength transducer elements to generate acoustic emissions according to a selectable acoustic transmission pattern. A common port may facilitate electromagnetic communication with each of the sub-wavelength transducer elements.
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